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Gene Ontology Browser
Term Detail
GO term:exocytosis
Synonym: nonselective vesicle exocytosis
Synonym: vesicle exocytosis
GO id:GO:0006887
Definition:A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. This is the process in which most molecules are secreted from eukaryotic cells.
Number of paths to term: 10

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-asecretion by cell
                                        is-aacetylcholine secretion +
                                        is-aaspartate secretion +
                                        is-acatecholamine secretion +
                                        is-acontractile vacuole discharge
                                        is-aexocytosis [GO:0006887] (233 genes, 354 annotations)
                                                is-acalcium ion-dependent exocytosis +
                                                is-aconstitutive secretory pathway
                                                is-aexosomal secretion
                                                negatively-regulatesnegative regulation of exocytosis +
                                                is-aplatelet degranulation +
                                                positively-regulatespositive regulation of exocytosis +
                                                is-aregulated secretory pathway +
                                                regulatesregulation of exocytosis +
                                                is-asynaptic vesicle exocytosis +
                                                part-ofvesicle docking involved in exocytosis +
                                                part-ofvesicle tethering involved in exocytosis
                                        is-aextracellular matrix constituent secretion +
                                        is-aglutamate secretion +
                                        is-aglutamine secretion
                                        is-aglycine secretion +
                                        is-aoctopamine secretion +
                                        is-aprimary amine secretion +
                                        is-aprotein secretion +
                                        is-asecretion by lung epithelial cell involved in lung growth
                                        is-asecretion by the type IV secretion system +
                                        is-aserotonin secretion +
                                        is-asignal release +


Gene_Ontology
        is-abiological_process
                is-aestablishment of localization
                        is-aestablishment of localization in cell
                                is-asecretion by cell
                                        is-aacetylcholine secretion +
                                        is-aaspartate secretion +
                                        is-acatecholamine secretion +
                                        is-acontractile vacuole discharge
                                        is-aexocytosis [GO:0006887] (233 genes, 354 annotations)
                                                is-acalcium ion-dependent exocytosis +
                                                is-aconstitutive secretory pathway
                                                is-aexosomal secretion
                                                negatively-regulatesnegative regulation of exocytosis +
                                                is-aplatelet degranulation +
                                                positively-regulatespositive regulation of exocytosis +
                                                is-aregulated secretory pathway +
                                                regulatesregulation of exocytosis +
                                                is-asynaptic vesicle exocytosis +
                                                part-ofvesicle docking involved in exocytosis +
                                                part-ofvesicle tethering involved in exocytosis
                                        is-aextracellular matrix constituent secretion +
                                        is-aglutamate secretion +
                                        is-aglutamine secretion
                                        is-aglycine secretion +
                                        is-aoctopamine secretion +
                                        is-aprimary amine secretion +
                                        is-aprotein secretion +
                                        is-asecretion by lung epithelial cell involved in lung growth
                                        is-asecretion by the type IV secretion system +
                                        is-aserotonin secretion +
                                        is-asignal release +


Gene_Ontology
        is-abiological_process
                is-aestablishment of localization
                        is-atransport
                                is-asingle-organism transport
                                        is-asecretion
                                                is-asecretion by cell
                                                        is-aacetylcholine secretion +
                                                        is-aaspartate secretion +
                                                        is-acatecholamine secretion +
                                                        is-acontractile vacuole discharge
                                                        is-aexocytosis [GO:0006887] (233 genes, 354 annotations)
                                                                is-acalcium ion-dependent exocytosis +
                                                                is-aconstitutive secretory pathway
                                                                is-aexosomal secretion
                                                                negatively-regulatesnegative regulation of exocytosis +
                                                                is-aplatelet degranulation +
                                                                positively-regulatespositive regulation of exocytosis +
                                                                is-aregulated secretory pathway +
                                                                regulatesregulation of exocytosis +
                                                                is-asynaptic vesicle exocytosis +
                                                                part-ofvesicle docking involved in exocytosis +
                                                                part-ofvesicle tethering involved in exocytosis
                                                        is-aextracellular matrix constituent secretion +
                                                        is-aglutamate secretion +
                                                        is-aglutamine secretion
                                                        is-aglycine secretion +
                                                        is-aoctopamine secretion +
                                                        is-aprimary amine secretion +
                                                        is-aprotein secretion +
                                                        is-asecretion by lung epithelial cell involved in lung growth
                                                        is-asecretion by the type IV secretion system +
                                                        is-aserotonin secretion +
                                                        is-asignal release +


Gene_Ontology
        is-abiological_process
                is-aestablishment of localization
                        is-atransport
                                is-avesicle-mediated transport
                                        part-ofcargo loading into vesicle +
                                        is-acontractile vacuole discharge
                                        is-aearly endosome to late endosome transport +
                                        is-aearly endosome to recycling endosome transport +
                                        is-aendocytic recycling +
                                        is-aendocytosis +
                                        is-aexocytosis [GO:0006887] (233 genes, 354 annotations)
                                                is-acalcium ion-dependent exocytosis +
                                                is-aconstitutive secretory pathway
                                                is-aexosomal secretion
                                                negatively-regulatesnegative regulation of exocytosis +
                                                is-aplatelet degranulation +
                                                positively-regulatespositive regulation of exocytosis +
                                                is-aregulated secretory pathway +
                                                regulatesregulation of exocytosis +
                                                is-asynaptic vesicle exocytosis +
                                                part-ofvesicle docking involved in exocytosis +
                                                part-ofvesicle tethering involved in exocytosis
                                        is-aGolgi vesicle transport +
                                        part-ofmembrane budding +
                                        is-amultivesicular body sorting pathway
                                        is-aplasma membrane to endosome transport
                                        regulatesregulation of vesicle-mediated transport +
                                        is-aretrograde transport, endosome to Golgi +
                                        is-aretrograde transport, endosome to plasma membrane
                                        is-aretrograde transport, plasma membrane to Golgi
                                        part-ofSNARE complex disassembly +
                                        is-asynaptic vesicle transport +
                                        is-atranscytosis +
                                        part-ofvesicle docking +
                                        part-ofvesicle fusion +
                                        part-ofvesicle targeting +
                                        part-ofvesicle uncoating +
                                        is-avesicle-mediated transport involved in floral organ abscission +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-acellular localization
                                part-ofestablishment of localization in cell
                                        is-asecretion by cell
                                                is-aacetylcholine secretion +
                                                is-aaspartate secretion +
                                                is-acatecholamine secretion +
                                                is-acontractile vacuole discharge
                                                is-aexocytosis [GO:0006887] (233 genes, 354 annotations)
                                                        is-acalcium ion-dependent exocytosis +
                                                        is-aconstitutive secretory pathway
                                                        is-aexosomal secretion
                                                        negatively-regulatesnegative regulation of exocytosis +
                                                        is-aplatelet degranulation +
                                                        positively-regulatespositive regulation of exocytosis +
                                                        is-aregulated secretory pathway +
                                                        regulatesregulation of exocytosis +
                                                        is-asynaptic vesicle exocytosis +
                                                        part-ofvesicle docking involved in exocytosis +
                                                        part-ofvesicle tethering involved in exocytosis
                                                is-aextracellular matrix constituent secretion +
                                                is-aglutamate secretion +
                                                is-aglutamine secretion
                                                is-aglycine secretion +
                                                is-aoctopamine secretion +
                                                is-aprimary amine secretion +
                                                is-aprotein secretion +
                                                is-asecretion by lung epithelial cell involved in lung growth
                                                is-asecretion by the type IV secretion system +
                                                is-aserotonin secretion +
                                                is-asignal release +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        part-ofestablishment of localization
                                is-aestablishment of localization in cell
                                        is-asecretion by cell
                                                is-aacetylcholine secretion +
                                                is-aaspartate secretion +
                                                is-acatecholamine secretion +
                                                is-acontractile vacuole discharge
                                                is-aexocytosis [GO:0006887] (233 genes, 354 annotations)
                                                        is-acalcium ion-dependent exocytosis +
                                                        is-aconstitutive secretory pathway
                                                        is-aexosomal secretion
                                                        negatively-regulatesnegative regulation of exocytosis +
                                                        is-aplatelet degranulation +
                                                        positively-regulatespositive regulation of exocytosis +
                                                        is-aregulated secretory pathway +
                                                        regulatesregulation of exocytosis +
                                                        is-asynaptic vesicle exocytosis +
                                                        part-ofvesicle docking involved in exocytosis +
                                                        part-ofvesicle tethering involved in exocytosis
                                                is-aextracellular matrix constituent secretion +
                                                is-aglutamate secretion +
                                                is-aglutamine secretion
                                                is-aglycine secretion +
                                                is-aoctopamine secretion +
                                                is-aprimary amine secretion +
                                                is-aprotein secretion +
                                                is-asecretion by lung epithelial cell involved in lung growth
                                                is-asecretion by the type IV secretion system +
                                                is-aserotonin secretion +
                                                is-asignal release +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        part-ofestablishment of localization
                                is-atransport
                                        is-asingle-organism transport
                                                is-asecretion
                                                        is-asecretion by cell
                                                                is-aacetylcholine secretion +
                                                                is-aaspartate secretion +
                                                                is-acatecholamine secretion +
                                                                is-acontractile vacuole discharge
                                                                is-aexocytosis [GO:0006887] (233 genes, 354 annotations)
                                                                        is-acalcium ion-dependent exocytosis +
                                                                        is-aconstitutive secretory pathway
                                                                        is-aexosomal secretion
                                                                        negatively-regulatesnegative regulation of exocytosis +
                                                                        is-aplatelet degranulation +
                                                                        positively-regulatespositive regulation of exocytosis +
                                                                        is-aregulated secretory pathway +
                                                                        regulatesregulation of exocytosis +
                                                                        is-asynaptic vesicle exocytosis +
                                                                        part-ofvesicle docking involved in exocytosis +
                                                                        part-ofvesicle tethering involved in exocytosis
                                                                is-aextracellular matrix constituent secretion +
                                                                is-aglutamate secretion +
                                                                is-aglutamine secretion
                                                                is-aglycine secretion +
                                                                is-aoctopamine secretion +
                                                                is-aprimary amine secretion +
                                                                is-aprotein secretion +
                                                                is-asecretion by lung epithelial cell involved in lung growth
                                                                is-asecretion by the type IV secretion system +
                                                                is-aserotonin secretion +
                                                                is-asignal release +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        part-ofestablishment of localization
                                is-atransport
                                        is-avesicle-mediated transport
                                                part-ofcargo loading into vesicle +
                                                is-acontractile vacuole discharge
                                                is-aearly endosome to late endosome transport +
                                                is-aearly endosome to recycling endosome transport +
                                                is-aendocytic recycling +
                                                is-aendocytosis +
                                                is-aexocytosis [GO:0006887] (233 genes, 354 annotations)
                                                        is-acalcium ion-dependent exocytosis +
                                                        is-aconstitutive secretory pathway
                                                        is-aexosomal secretion
                                                        negatively-regulatesnegative regulation of exocytosis +
                                                        is-aplatelet degranulation +
                                                        positively-regulatespositive regulation of exocytosis +
                                                        is-aregulated secretory pathway +
                                                        regulatesregulation of exocytosis +
                                                        is-asynaptic vesicle exocytosis +
                                                        part-ofvesicle docking involved in exocytosis +
                                                        part-ofvesicle tethering involved in exocytosis
                                                is-aGolgi vesicle transport +
                                                part-ofmembrane budding +
                                                is-amultivesicular body sorting pathway
                                                is-aplasma membrane to endosome transport
                                                regulatesregulation of vesicle-mediated transport +
                                                is-aretrograde transport, endosome to Golgi +
                                                is-aretrograde transport, endosome to plasma membrane
                                                is-aretrograde transport, plasma membrane to Golgi
                                                part-ofSNARE complex disassembly +
                                                is-asynaptic vesicle transport +
                                                is-atranscytosis +
                                                part-ofvesicle docking +
                                                part-ofvesicle fusion +
                                                part-ofvesicle targeting +
                                                part-ofvesicle uncoating +
                                                is-avesicle-mediated transport involved in floral organ abscission +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-asecretion by cell
                                        is-aacetylcholine secretion +
                                        is-aaspartate secretion +
                                        is-acatecholamine secretion +
                                        is-acontractile vacuole discharge
                                        is-aexocytosis [GO:0006887] (233 genes, 354 annotations)
                                                is-acalcium ion-dependent exocytosis +
                                                is-aconstitutive secretory pathway
                                                is-aexosomal secretion
                                                negatively-regulatesnegative regulation of exocytosis +
                                                is-aplatelet degranulation +
                                                positively-regulatespositive regulation of exocytosis +
                                                is-aregulated secretory pathway +
                                                regulatesregulation of exocytosis +
                                                is-asynaptic vesicle exocytosis +
                                                part-ofvesicle docking involved in exocytosis +
                                                part-ofvesicle tethering involved in exocytosis
                                        is-aextracellular matrix constituent secretion +
                                        is-aglutamate secretion +
                                        is-aglutamine secretion
                                        is-aglycine secretion +
                                        is-aoctopamine secretion +
                                        is-aprimary amine secretion +
                                        is-aprotein secretion +
                                        is-asecretion by lung epithelial cell involved in lung growth
                                        is-asecretion by the type IV secretion system +
                                        is-aserotonin secretion +
                                        is-asignal release +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism transport
                                is-asecretion
                                        is-asecretion by cell
                                                is-aacetylcholine secretion +
                                                is-aaspartate secretion +
                                                is-acatecholamine secretion +
                                                is-acontractile vacuole discharge
                                                is-aexocytosis [GO:0006887] (233 genes, 354 annotations)
                                                        is-acalcium ion-dependent exocytosis +
                                                        is-aconstitutive secretory pathway
                                                        is-aexosomal secretion
                                                        negatively-regulatesnegative regulation of exocytosis +
                                                        is-aplatelet degranulation +
                                                        positively-regulatespositive regulation of exocytosis +
                                                        is-aregulated secretory pathway +
                                                        regulatesregulation of exocytosis +
                                                        is-asynaptic vesicle exocytosis +
                                                        part-ofvesicle docking involved in exocytosis +
                                                        part-ofvesicle tethering involved in exocytosis
                                                is-aextracellular matrix constituent secretion +
                                                is-aglutamate secretion +
                                                is-aglutamine secretion
                                                is-aglycine secretion +
                                                is-aoctopamine secretion +
                                                is-aprimary amine secretion +
                                                is-aprotein secretion +
                                                is-asecretion by lung epithelial cell involved in lung growth
                                                is-asecretion by the type IV secretion system +
                                                is-aserotonin secretion +
                                                is-asignal release +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory