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Term Detail
GO term:nucleocytoplasmic transport
Synonym: nucleocytoplasmic shuttling
GO id:GO:0006913
Alternate id: GO:0000063
Definition:The directed movement of molecules between the nucleus and the cytoplasm.
CommentsNote that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane, and is not traversed.
Number of paths to term: 4

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-acellular localization
                                part-ofestablishment of localization in cell
                                        is-aintracellular transport
                                                is-anuclear transport
                                                        is-amicrotubule-dependent intracellular transport of viral material towards nucleus
                                                        is-anucleocytoplasmic transport [GO:0006913] (385 genes, 593 annotations)
                                                                negatively-regulatesnegative regulation of nucleocytoplasmic transport +
                                                                is-anuclear export +
                                                                is-anuclear import +
                                                                positively-regulatespositive regulation of nuclear envelope permeability
                                                                positively-regulatespositive regulation of nucleocytoplasmic transport +
                                                                regulatesregulation of nucleocytoplasmic transport +
                                                        is-anucleolus to nucleoplasm transport
                                                        is-aprotein targeting to nucleus +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-acellular localization
                                is-aintracellular transport
                                        is-anuclear transport
                                                is-amicrotubule-dependent intracellular transport of viral material towards nucleus
                                                is-anucleocytoplasmic transport [GO:0006913] (385 genes, 593 annotations)
                                                        negatively-regulatesnegative regulation of nucleocytoplasmic transport +
                                                        is-anuclear export +
                                                        is-anuclear import +
                                                        positively-regulatespositive regulation of nuclear envelope permeability
                                                        positively-regulatespositive regulation of nucleocytoplasmic transport +
                                                        regulatesregulation of nucleocytoplasmic transport +
                                                is-anucleolus to nucleoplasm transport
                                                is-aprotein targeting to nucleus +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-aestablishment of localization in cell
                                        is-aintracellular transport
                                                is-anuclear transport
                                                        is-amicrotubule-dependent intracellular transport of viral material towards nucleus
                                                        is-anucleocytoplasmic transport [GO:0006913] (385 genes, 593 annotations)
                                                                negatively-regulatesnegative regulation of nucleocytoplasmic transport +
                                                                is-anuclear export +
                                                                is-anuclear import +
                                                                positively-regulatespositive regulation of nuclear envelope permeability
                                                                positively-regulatespositive regulation of nucleocytoplasmic transport +
                                                                regulatesregulation of nucleocytoplasmic transport +
                                                        is-anucleolus to nucleoplasm transport
                                                        is-aprotein targeting to nucleus +


obsolete Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-aintracellular transport
                                                is-anuclear transport
                                                        is-amicrotubule-dependent intracellular transport of viral material towards nucleus
                                                        is-anucleocytoplasmic transport [GO:0006913] (385 genes, 593 annotations)
                                                                negatively-regulatesnegative regulation of nucleocytoplasmic transport +
                                                                is-anuclear export +
                                                                is-anuclear import +
                                                                positively-regulatespositive regulation of nuclear envelope permeability
                                                                positively-regulatespositive regulation of nucleocytoplasmic transport +
                                                                regulatesregulation of nucleocytoplasmic transport +
                                                        is-anucleolus to nucleoplasm transport
                                                        is-aprotein targeting to nucleus +


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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory