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Gene Ontology Browser
Term Detail
GO term:filopodium
GO id:GO:0030175
Alternate id: GO:0030028
Definition:Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.
CommentsA filopodium may be approximately 0.1 um wide, 5-10 um long, and up to 50 um long in axon growth cones; contain a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward. Note that filopodia on dendritic shafts are distinct from other types of filopodia (even those found in dendritic growth cones) and may react differently to stimuli, as shown in PMID:12904473.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-acell projection
                                        is-aactin-based cell projection
                                                part-ofactin filament bundle of actin-based cell projection +
                                                is-afilopodium [GO:0030175] (79 genes, 94 annotations)
                                                        part-ofactin filament bundle of filopodium
                                                        is-adendritic filopodium
                                                        part-offilopodium membrane
                                                        part-offilopodium tip
                                                        is-agrowth cone filopodium
                                                is-amicrovillus +
                                                is-astereocilium +


obsolete Gene_Ontology
        is-acellular_component
                is-acell part
                        is-acell projection
                                is-aactin-based cell projection
                                        part-ofactin filament bundle of actin-based cell projection +
                                        is-afilopodium [GO:0030175] (79 genes, 94 annotations)
                                                part-ofactin filament bundle of filopodium
                                                is-adendritic filopodium
                                                part-offilopodium membrane
                                                part-offilopodium tip
                                                is-agrowth cone filopodium
                                        is-amicrovillus +
                                        is-astereocilium +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory