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Gene Ontology Browser
Term Detail
GO term:filopodium
GO id:GO:0030175
Definition:Thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.
CommentsA filopodium may be approximately 0.1 um wide, 5-10 um long, and up to 50 um long in axon growth cones; may contain a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward. Note that filopodia on dendritic shafts are distinct from other types of filopodia (even those found in dendritic growth cones) and may react differently to stimuli, as shown in PMID:12904473.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-acell projection
                                        is-aarchaeal-type flagellum
                                        is-abacterial-type flagellum +
                                        is-ableb
                                        is-abrush border +
                                        is-acell hair
                                        part-ofcell projection part +
                                        is-acilium +
                                        is-acytoneme
                                        is-adendritic cell dendrite
                                        is-afilopodium [GO:0030175] (61 genes, 71 annotations)
                                                is-adendritic filopodium
                                                part-offilopodium membrane
                                                part-offilopodium tip
                                        is-aglial cell projection +
                                        is-ahaustorium +
                                        is-ainvadopodium +
                                        is-alamellipodium +
                                        is-amacropinocytic cup +
                                        is-amating projection +
                                        is-amicrospike
                                        is-amicrovillus +
                                        is-amuscle cell projection +
                                        is-aneuron projection +
                                        is-aoral apparatus +
                                        is-apilus +
                                        is-aplant cell papilla +
                                        is-apollen tube +
                                        is-apseudopodium +
                                        is-arhabdomere +
                                        is-aroot hair +
                                        is-aruffle +
                                        is-auropod +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-acell projection
                                is-aarchaeal-type flagellum
                                is-abacterial-type flagellum +
                                is-ableb
                                is-abrush border +
                                is-acell hair
                                part-ofcell projection part +
                                is-acilium +
                                is-acytoneme
                                is-adendritic cell dendrite
                                is-afilopodium [GO:0030175] (61 genes, 71 annotations)
                                        is-adendritic filopodium
                                        part-offilopodium membrane
                                        part-offilopodium tip
                                is-aglial cell projection +
                                is-ahaustorium +
                                is-ainvadopodium +
                                is-alamellipodium +
                                is-amacropinocytic cup +
                                is-amating projection +
                                is-amicrospike
                                is-amicrovillus +
                                is-amuscle cell projection +
                                is-aneuron projection +
                                is-aoral apparatus +
                                is-apilus +
                                is-aplant cell papilla +
                                is-apollen tube +
                                is-apseudopodium +
                                is-arhabdomere +
                                is-aroot hair +
                                is-aruffle +
                                is-auropod +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory