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Gene Ontology Browser
Term Detail
GO term:cytoskeleton
GO id:GO:0005856
Definition:Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
Number of paths to term: 6

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-aintracellular organelle
                                                        is-aintracellular non-membrane-bounded organelle
                                                                is-aaster +
                                                                is-abacterial nucleoid +
                                                                is-abacterial thylakoid +
                                                                is-acentriole
                                                                is-acentrosome +
                                                                is-achlorosome +
                                                                is-achromosome +
                                                                is-acontractile fiber +
                                                                is-acrystalloid
                                                                is-acytoskeleton [GO:0005856] (1816 genes, 3729 annotations)
                                                                        is-aactin cytoskeleton +
                                                                        is-acortical cytoskeleton +
                                                                        part-ofcytoskeletal part +
                                                                        part-ofgoblet cell theca
                                                                        is-aintermediate filament cytoskeleton +
                                                                        is-amicrotubule cytoskeleton +
                                                                        is-aperinuclear theca +
                                                                        is-aseptin cytoskeleton +
                                                                        is-aspectrin-associated cytoskeleton
                                                                is-adeuterosome
                                                                is-agas vesicle +
                                                                is-agoblet cell theca
                                                                is-akinetochore +
                                                                is-alipid particle +
                                                                is-amitochondrial cloud
                                                                is-amitochondrial nucleoid +
                                                                is-anematocyst
                                                                is-anucleolus +
                                                                is-aplastid nucleoid +
                                                                is-apodosome
                                                                is-apolyhedral organelle +
                                                                is-aribonucleoprotein granule +
                                                                is-aribosome +
                                                                is-aspectrosome
                                                                is-aspindle +
                                                                is-astereocilium bundle +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-aintracellular organelle
                                                is-aintracellular non-membrane-bounded organelle
                                                        is-aaster +
                                                        is-abacterial nucleoid +
                                                        is-abacterial thylakoid +
                                                        is-acentriole
                                                        is-acentrosome +
                                                        is-achlorosome +
                                                        is-achromosome +
                                                        is-acontractile fiber +
                                                        is-acrystalloid
                                                        is-acytoskeleton [GO:0005856] (1816 genes, 3729 annotations)
                                                                is-aactin cytoskeleton +
                                                                is-acortical cytoskeleton +
                                                                part-ofcytoskeletal part +
                                                                part-ofgoblet cell theca
                                                                is-aintermediate filament cytoskeleton +
                                                                is-amicrotubule cytoskeleton +
                                                                is-aperinuclear theca +
                                                                is-aseptin cytoskeleton +
                                                                is-aspectrin-associated cytoskeleton
                                                        is-adeuterosome
                                                        is-agas vesicle +
                                                        is-agoblet cell theca
                                                        is-akinetochore +
                                                        is-alipid particle +
                                                        is-amitochondrial cloud
                                                        is-amitochondrial nucleoid +
                                                        is-anematocyst
                                                        is-anucleolus +
                                                        is-aplastid nucleoid +
                                                        is-apodosome
                                                        is-apolyhedral organelle +
                                                        is-aribonucleoprotein granule +
                                                        is-aribosome +
                                                        is-aspectrosome
                                                        is-aspindle +
                                                        is-astereocilium bundle +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-aintracellular organelle
                                                is-aintracellular non-membrane-bounded organelle
                                                        is-aaster +
                                                        is-abacterial nucleoid +
                                                        is-abacterial thylakoid +
                                                        is-acentriole
                                                        is-acentrosome +
                                                        is-achlorosome +
                                                        is-achromosome +
                                                        is-acontractile fiber +
                                                        is-acrystalloid
                                                        is-acytoskeleton [GO:0005856] (1816 genes, 3729 annotations)
                                                                is-aactin cytoskeleton +
                                                                is-acortical cytoskeleton +
                                                                part-ofcytoskeletal part +
                                                                part-ofgoblet cell theca
                                                                is-aintermediate filament cytoskeleton +
                                                                is-amicrotubule cytoskeleton +
                                                                is-aperinuclear theca +
                                                                is-aseptin cytoskeleton +
                                                                is-aspectrin-associated cytoskeleton
                                                        is-adeuterosome
                                                        is-agas vesicle +
                                                        is-agoblet cell theca
                                                        is-akinetochore +
                                                        is-alipid particle +
                                                        is-amitochondrial cloud
                                                        is-amitochondrial nucleoid +
                                                        is-anematocyst
                                                        is-anucleolus +
                                                        is-aplastid nucleoid +
                                                        is-apodosome
                                                        is-apolyhedral organelle +
                                                        is-aribonucleoprotein granule +
                                                        is-aribosome +
                                                        is-aspectrosome
                                                        is-aspindle +
                                                        is-astereocilium bundle +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-aintracellular organelle
                                        is-aintracellular non-membrane-bounded organelle
                                                is-aaster +
                                                is-abacterial nucleoid +
                                                is-abacterial thylakoid +
                                                is-acentriole
                                                is-acentrosome +
                                                is-achlorosome +
                                                is-achromosome +
                                                is-acontractile fiber +
                                                is-acrystalloid
                                                is-acytoskeleton [GO:0005856] (1816 genes, 3729 annotations)
                                                        is-aactin cytoskeleton +
                                                        is-acortical cytoskeleton +
                                                        part-ofcytoskeletal part +
                                                        part-ofgoblet cell theca
                                                        is-aintermediate filament cytoskeleton +
                                                        is-amicrotubule cytoskeleton +
                                                        is-aperinuclear theca +
                                                        is-aseptin cytoskeleton +
                                                        is-aspectrin-associated cytoskeleton
                                                is-adeuterosome
                                                is-agas vesicle +
                                                is-agoblet cell theca
                                                is-akinetochore +
                                                is-alipid particle +
                                                is-amitochondrial cloud
                                                is-amitochondrial nucleoid +
                                                is-anematocyst
                                                is-anucleolus +
                                                is-aplastid nucleoid +
                                                is-apodosome
                                                is-apolyhedral organelle +
                                                is-aribonucleoprotein granule +
                                                is-aribosome +
                                                is-aspectrosome
                                                is-aspindle +
                                                is-astereocilium bundle +


Gene_Ontology
        is-acellular_component
                is-aorganelle
                        is-aintracellular organelle
                                is-aintracellular non-membrane-bounded organelle
                                        is-aaster +
                                        is-abacterial nucleoid +
                                        is-abacterial thylakoid +
                                        is-acentriole
                                        is-acentrosome +
                                        is-achlorosome +
                                        is-achromosome +
                                        is-acontractile fiber +
                                        is-acrystalloid
                                        is-acytoskeleton [GO:0005856] (1816 genes, 3729 annotations)
                                                is-aactin cytoskeleton +
                                                is-acortical cytoskeleton +
                                                part-ofcytoskeletal part +
                                                part-ofgoblet cell theca
                                                is-aintermediate filament cytoskeleton +
                                                is-amicrotubule cytoskeleton +
                                                is-aperinuclear theca +
                                                is-aseptin cytoskeleton +
                                                is-aspectrin-associated cytoskeleton
                                        is-adeuterosome
                                        is-agas vesicle +
                                        is-agoblet cell theca
                                        is-akinetochore +
                                        is-alipid particle +
                                        is-amitochondrial cloud
                                        is-amitochondrial nucleoid +
                                        is-anematocyst
                                        is-anucleolus +
                                        is-aplastid nucleoid +
                                        is-apodosome
                                        is-apolyhedral organelle +
                                        is-aribonucleoprotein granule +
                                        is-aribosome +
                                        is-aspectrosome
                                        is-aspindle +
                                        is-astereocilium bundle +


Gene_Ontology
        is-acellular_component
                is-aorganelle
                        is-anon-membrane-bounded organelle
                                is-aintracellular non-membrane-bounded organelle
                                        is-aaster +
                                        is-abacterial nucleoid +
                                        is-abacterial thylakoid +
                                        is-acentriole
                                        is-acentrosome +
                                        is-achlorosome +
                                        is-achromosome +
                                        is-acontractile fiber +
                                        is-acrystalloid
                                        is-acytoskeleton [GO:0005856] (1816 genes, 3729 annotations)
                                                is-aactin cytoskeleton +
                                                is-acortical cytoskeleton +
                                                part-ofcytoskeletal part +
                                                part-ofgoblet cell theca
                                                is-aintermediate filament cytoskeleton +
                                                is-amicrotubule cytoskeleton +
                                                is-aperinuclear theca +
                                                is-aseptin cytoskeleton +
                                                is-aspectrin-associated cytoskeleton
                                        is-adeuterosome
                                        is-agas vesicle +
                                        is-agoblet cell theca
                                        is-akinetochore +
                                        is-alipid particle +
                                        is-amitochondrial cloud
                                        is-amitochondrial nucleoid +
                                        is-anematocyst
                                        is-anucleolus +
                                        is-aplastid nucleoid +
                                        is-apodosome
                                        is-apolyhedral organelle +
                                        is-aribonucleoprotein granule +
                                        is-aribosome +
                                        is-aspectrosome
                                        is-aspindle +
                                        is-astereocilium bundle +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory