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Gene Ontology Browser
Term Detail
GO term:type B pancreatic cell differentiation
Synonym: pancreatic B cell differentiation
Synonym: pancreatic beta cell differentiation
GO id:GO:0003309
Definition:The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.
Number of paths to term: 21

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-aepithelial cell differentiation
                                                        is-acolumnar/cuboidal epithelial cell differentiation
                                                                is-aglandular epithelial cell differentiation
                                                                        is-aenteroendocrine cell differentiation
                                                                                is-apancreatic A cell differentiation +
                                                                                is-apancreatic D cell differentiation +
                                                                                is-apancreatic PP cell differentiation +
                                                                                is-atype B pancreatic cell differentiation [GO:0003309] (23 genes, 29 annotations)
                                                                                        part-oftype B pancreatic cell development +
                                                                                        part-oftype B pancreatic cell fate commitment


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-aendocrine pancreas development
                                        part-ofpancreatic A cell differentiation +
                                        part-ofpancreatic D cell differentiation +
                                        part-ofpancreatic epsilon cell differentiation +
                                        part-ofpancreatic PP cell differentiation +
                                        part-oftype B pancreatic cell differentiation [GO:0003309] (23 genes, 29 annotations)
                                                part-oftype B pancreatic cell development +
                                                part-oftype B pancreatic cell fate commitment


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-aorgan development
                                        is-apancreas development
                                                part-ofendocrine pancreas development
                                                        part-ofpancreatic A cell differentiation +
                                                        part-ofpancreatic D cell differentiation +
                                                        part-ofpancreatic epsilon cell differentiation +
                                                        part-ofpancreatic PP cell differentiation +
                                                        part-oftype B pancreatic cell differentiation [GO:0003309] (23 genes, 29 annotations)
                                                                part-oftype B pancreatic cell development +
                                                                part-oftype B pancreatic cell fate commitment


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-asystem development
                                        is-aendocrine system development
                                                part-ofendocrine pancreas development
                                                        part-ofpancreatic A cell differentiation +
                                                        part-ofpancreatic D cell differentiation +
                                                        part-ofpancreatic epsilon cell differentiation +
                                                        part-ofpancreatic PP cell differentiation +
                                                        part-oftype B pancreatic cell differentiation [GO:0003309] (23 genes, 29 annotations)
                                                                part-oftype B pancreatic cell development +
                                                                part-oftype B pancreatic cell fate commitment


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-asystem development
                                        part-oforgan development
                                                is-apancreas development
                                                        part-ofendocrine pancreas development
                                                                part-ofpancreatic A cell differentiation +
                                                                part-ofpancreatic D cell differentiation +
                                                                part-ofpancreatic epsilon cell differentiation +
                                                                part-ofpancreatic PP cell differentiation +
                                                                part-oftype B pancreatic cell differentiation [GO:0003309] (23 genes, 29 annotations)
                                                                        part-oftype B pancreatic cell development +
                                                                        part-oftype B pancreatic cell fate commitment


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-atissue development
                                        is-aepithelium development
                                                part-ofepithelial cell differentiation
                                                        is-acolumnar/cuboidal epithelial cell differentiation
                                                                is-aglandular epithelial cell differentiation
                                                                        is-aenteroendocrine cell differentiation
                                                                                is-apancreatic A cell differentiation +
                                                                                is-apancreatic D cell differentiation +
                                                                                is-apancreatic PP cell differentiation +
                                                                                is-atype B pancreatic cell differentiation [GO:0003309] (23 genes, 29 annotations)
                                                                                        part-oftype B pancreatic cell development +
                                                                                        part-oftype B pancreatic cell fate commitment


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-aepithelial cell differentiation
                                                        is-acolumnar/cuboidal epithelial cell differentiation
                                                                is-aglandular epithelial cell differentiation
                                                                        is-aenteroendocrine cell differentiation
                                                                                is-apancreatic A cell differentiation +
                                                                                is-apancreatic D cell differentiation +
                                                                                is-apancreatic PP cell differentiation +
                                                                                is-atype B pancreatic cell differentiation [GO:0003309] (23 genes, 29 annotations)
                                                                                        part-oftype B pancreatic cell development +
                                                                                        part-oftype B pancreatic cell fate commitment


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-aendocrine pancreas development
                                        part-ofpancreatic A cell differentiation +
                                        part-ofpancreatic D cell differentiation +
                                        part-ofpancreatic epsilon cell differentiation +
                                        part-ofpancreatic PP cell differentiation +
                                        part-oftype B pancreatic cell differentiation [GO:0003309] (23 genes, 29 annotations)
                                                part-oftype B pancreatic cell development +
                                                part-oftype B pancreatic cell fate commitment


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-aendocrine system development
                                                        part-ofendocrine pancreas development
                                                                part-ofpancreatic A cell differentiation +
                                                                part-ofpancreatic D cell differentiation +
                                                                part-ofpancreatic epsilon cell differentiation +
                                                                part-ofpancreatic PP cell differentiation +
                                                                part-oftype B pancreatic cell differentiation [GO:0003309] (23 genes, 29 annotations)
                                                                        part-oftype B pancreatic cell development +
                                                                        part-oftype B pancreatic cell fate commitment


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-apancreas development
                                                                part-ofendocrine pancreas development
                                                                        part-ofpancreatic A cell differentiation +
                                                                        part-ofpancreatic D cell differentiation +
                                                                        part-ofpancreatic epsilon cell differentiation +
                                                                        part-ofpancreatic PP cell differentiation +
                                                                        part-oftype B pancreatic cell differentiation [GO:0003309] (23 genes, 29 annotations)
                                                                                part-oftype B pancreatic cell development +
                                                                                part-oftype B pancreatic cell fate commitment


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-apancreas development
                                        part-ofendocrine pancreas development
                                                part-ofpancreatic A cell differentiation +
                                                part-ofpancreatic D cell differentiation +
                                                part-ofpancreatic epsilon cell differentiation +
                                                part-ofpancreatic PP cell differentiation +
                                                part-oftype B pancreatic cell differentiation [GO:0003309] (23 genes, 29 annotations)
                                                        part-oftype B pancreatic cell development +
                                                        part-oftype B pancreatic cell fate commitment


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-aendocrine system development
                                                        part-ofendocrine pancreas development
                                                                part-ofpancreatic A cell differentiation +
                                                                part-ofpancreatic D cell differentiation +
                                                                part-ofpancreatic epsilon cell differentiation +
                                                                part-ofpancreatic PP cell differentiation +
                                                                part-oftype B pancreatic cell differentiation [GO:0003309] (23 genes, 29 annotations)
                                                                        part-oftype B pancreatic cell development +
                                                                        part-oftype B pancreatic cell fate commitment


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-apancreas development
                                                                part-ofendocrine pancreas development
                                                                        part-ofpancreatic A cell differentiation +
                                                                        part-ofpancreatic D cell differentiation +
                                                                        part-ofpancreatic epsilon cell differentiation +
                                                                        part-ofpancreatic PP cell differentiation +
                                                                        part-oftype B pancreatic cell differentiation [GO:0003309] (23 genes, 29 annotations)
                                                                                part-oftype B pancreatic cell development +
                                                                                part-oftype B pancreatic cell fate commitment


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-aendocrine system development
                                                        part-ofendocrine pancreas development
                                                                part-ofpancreatic A cell differentiation +
                                                                part-ofpancreatic D cell differentiation +
                                                                part-ofpancreatic epsilon cell differentiation +
                                                                part-ofpancreatic PP cell differentiation +
                                                                part-oftype B pancreatic cell differentiation [GO:0003309] (23 genes, 29 annotations)
                                                                        part-oftype B pancreatic cell development +
                                                                        part-oftype B pancreatic cell fate commitment


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-apancreas development
                                                                part-ofendocrine pancreas development
                                                                        part-ofpancreatic A cell differentiation +
                                                                        part-ofpancreatic D cell differentiation +
                                                                        part-ofpancreatic epsilon cell differentiation +
                                                                        part-ofpancreatic PP cell differentiation +
                                                                        part-oftype B pancreatic cell differentiation [GO:0003309] (23 genes, 29 annotations)
                                                                                part-oftype B pancreatic cell development +
                                                                                part-oftype B pancreatic cell fate commitment


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-aepithelial cell differentiation
                                                        is-acolumnar/cuboidal epithelial cell differentiation
                                                                is-aglandular epithelial cell differentiation
                                                                        is-aenteroendocrine cell differentiation
                                                                                is-apancreatic A cell differentiation +
                                                                                is-apancreatic D cell differentiation +
                                                                                is-apancreatic PP cell differentiation +
                                                                                is-atype B pancreatic cell differentiation [GO:0003309] (23 genes, 29 annotations)
                                                                                        part-oftype B pancreatic cell development +
                                                                                        part-oftype B pancreatic cell fate commitment


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-aepithelial cell differentiation
                                                        is-acolumnar/cuboidal epithelial cell differentiation
                                                                is-aglandular epithelial cell differentiation
                                                                        is-aenteroendocrine cell differentiation
                                                                                is-apancreatic A cell differentiation +
                                                                                is-apancreatic D cell differentiation +
                                                                                is-apancreatic PP cell differentiation +
                                                                                is-atype B pancreatic cell differentiation [GO:0003309] (23 genes, 29 annotations)
                                                                                        part-oftype B pancreatic cell development +
                                                                                        part-oftype B pancreatic cell fate commitment


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-aendocrine pancreas development
                                        part-ofpancreatic A cell differentiation +
                                        part-ofpancreatic D cell differentiation +
                                        part-ofpancreatic epsilon cell differentiation +
                                        part-ofpancreatic PP cell differentiation +
                                        part-oftype B pancreatic cell differentiation [GO:0003309] (23 genes, 29 annotations)
                                                part-oftype B pancreatic cell development +
                                                part-oftype B pancreatic cell fate commitment


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-aendocrine system development
                                                        part-ofendocrine pancreas development
                                                                part-ofpancreatic A cell differentiation +
                                                                part-ofpancreatic D cell differentiation +
                                                                part-ofpancreatic epsilon cell differentiation +
                                                                part-ofpancreatic PP cell differentiation +
                                                                part-oftype B pancreatic cell differentiation [GO:0003309] (23 genes, 29 annotations)
                                                                        part-oftype B pancreatic cell development +
                                                                        part-oftype B pancreatic cell fate commitment


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-apancreas development
                                                                part-ofendocrine pancreas development
                                                                        part-ofpancreatic A cell differentiation +
                                                                        part-ofpancreatic D cell differentiation +
                                                                        part-ofpancreatic epsilon cell differentiation +
                                                                        part-ofpancreatic PP cell differentiation +
                                                                        part-oftype B pancreatic cell differentiation [GO:0003309] (23 genes, 29 annotations)
                                                                                part-oftype B pancreatic cell development +
                                                                                part-oftype B pancreatic cell fate commitment


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-apancreas development
                                        part-ofendocrine pancreas development
                                                part-ofpancreatic A cell differentiation +
                                                part-ofpancreatic D cell differentiation +
                                                part-ofpancreatic epsilon cell differentiation +
                                                part-ofpancreatic PP cell differentiation +
                                                part-oftype B pancreatic cell differentiation [GO:0003309] (23 genes, 29 annotations)
                                                        part-oftype B pancreatic cell development +
                                                        part-oftype B pancreatic cell fate commitment


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory