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Gene Ontology Browser
Term Detail
GO term:negative regulation of synaptic plasticity
Synonym: down regulation of synaptic plasticity
Synonym: down-regulation of synaptic plasticity
Synonym: downregulation of synaptic plasticity
Synonym: inhibition of synaptic plasticity
GO id:GO:0031914
Definition:A process that decreases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
Number of paths to term: 13

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-aregulation of synapse structure or activity
                                        is-aregulation of synaptic plasticity
                                                is-along term synaptic depression +
                                                is-along-term synaptic potentiation +
                                                is-anegative regulation of synaptic plasticity [GO:0031914] (4 genes, 4 annotations)
                                                        is-anegative regulation of synaptic metaplasticity
                                                is-apositive regulation of synaptic plasticity +
                                                is-aregulation of long term synaptic depression +
                                                is-aregulation of long-term synaptic potentiation +
                                                is-aregulation of neuronal synaptic plasticity +
                                                is-aregulation of synaptic metaplasticity +
                                                is-aregulation of synaptic plasticity by chemical substance +
                                                is-ashort-term synaptic potentiation


obsolete Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of cellular process
                                is-aregulation of cell communication
                                        is-amodulation of synaptic transmission
                                                is-aregulation of synaptic plasticity
                                                        is-along term synaptic depression +
                                                        is-along-term synaptic potentiation +
                                                        is-anegative regulation of synaptic plasticity [GO:0031914] (4 genes, 4 annotations)
                                                                is-anegative regulation of synaptic metaplasticity
                                                        is-apositive regulation of synaptic plasticity +
                                                        is-aregulation of long term synaptic depression +
                                                        is-aregulation of long-term synaptic potentiation +
                                                        is-aregulation of neuronal synaptic plasticity +
                                                        is-aregulation of synaptic metaplasticity +
                                                        is-aregulation of synaptic plasticity by chemical substance +
                                                        is-ashort-term synaptic potentiation


obsolete Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of signaling
                                is-amodulation of synaptic transmission
                                        is-aregulation of synaptic plasticity
                                                is-along term synaptic depression +
                                                is-along-term synaptic potentiation +
                                                is-anegative regulation of synaptic plasticity [GO:0031914] (4 genes, 4 annotations)
                                                        is-anegative regulation of synaptic metaplasticity
                                                is-apositive regulation of synaptic plasticity +
                                                is-aregulation of long term synaptic depression +
                                                is-aregulation of long-term synaptic potentiation +
                                                is-aregulation of neuronal synaptic plasticity +
                                                is-aregulation of synaptic metaplasticity +
                                                is-aregulation of synaptic plasticity by chemical substance +
                                                is-ashort-term synaptic potentiation


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-aregulation of cell communication
                                        is-amodulation of synaptic transmission
                                                is-aregulation of synaptic plasticity
                                                        is-along term synaptic depression +
                                                        is-along-term synaptic potentiation +
                                                        is-anegative regulation of synaptic plasticity [GO:0031914] (4 genes, 4 annotations)
                                                                is-anegative regulation of synaptic metaplasticity
                                                        is-apositive regulation of synaptic plasticity +
                                                        is-aregulation of long term synaptic depression +
                                                        is-aregulation of long-term synaptic potentiation +
                                                        is-aregulation of neuronal synaptic plasticity +
                                                        is-aregulation of synaptic metaplasticity +
                                                        is-aregulation of synaptic plasticity by chemical substance +
                                                        is-ashort-term synaptic potentiation


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        is-acell-cell signaling
                                                is-asynaptic signaling
                                                        is-atrans-synaptic signaling
                                                                is-aanterograde trans-synaptic signaling
                                                                        is-achemical synaptic transmission
                                                                                regulatesmodulation of synaptic transmission
                                                                                        is-aregulation of synaptic plasticity
                                                                                                is-along term synaptic depression +
                                                                                                is-along-term synaptic potentiation +
                                                                                                is-anegative regulation of synaptic plasticity [GO:0031914] (4 genes, 4 annotations)
                                                                                                        is-anegative regulation of synaptic metaplasticity
                                                                                                is-apositive regulation of synaptic plasticity +
                                                                                                is-aregulation of long term synaptic depression +
                                                                                                is-aregulation of long-term synaptic potentiation +
                                                                                                is-aregulation of neuronal synaptic plasticity +
                                                                                                is-aregulation of synaptic metaplasticity +
                                                                                                is-aregulation of synaptic plasticity by chemical substance +
                                                                                                is-ashort-term synaptic potentiation


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        regulatesregulation of cell communication
                                                is-amodulation of synaptic transmission
                                                        is-aregulation of synaptic plasticity
                                                                is-along term synaptic depression +
                                                                is-along-term synaptic potentiation +
                                                                is-anegative regulation of synaptic plasticity [GO:0031914] (4 genes, 4 annotations)
                                                                        is-anegative regulation of synaptic metaplasticity
                                                                is-apositive regulation of synaptic plasticity +
                                                                is-aregulation of long term synaptic depression +
                                                                is-aregulation of long-term synaptic potentiation +
                                                                is-aregulation of neuronal synaptic plasticity +
                                                                is-aregulation of synaptic metaplasticity +
                                                                is-aregulation of synaptic plasticity by chemical substance +
                                                                is-ashort-term synaptic potentiation


obsolete Gene_Ontology
        is-abiological_process
                is-aregulation of biological process
                        is-aregulation of cellular process
                                is-aregulation of cell communication
                                        is-amodulation of synaptic transmission
                                                is-aregulation of synaptic plasticity
                                                        is-along term synaptic depression +
                                                        is-along-term synaptic potentiation +
                                                        is-anegative regulation of synaptic plasticity [GO:0031914] (4 genes, 4 annotations)
                                                                is-anegative regulation of synaptic metaplasticity
                                                        is-apositive regulation of synaptic plasticity +
                                                        is-aregulation of long term synaptic depression +
                                                        is-aregulation of long-term synaptic potentiation +
                                                        is-aregulation of neuronal synaptic plasticity +
                                                        is-aregulation of synaptic metaplasticity +
                                                        is-aregulation of synaptic plasticity by chemical substance +
                                                        is-ashort-term synaptic potentiation


obsolete Gene_Ontology
        is-abiological_process
                is-aregulation of biological process
                        is-aregulation of signaling
                                is-amodulation of synaptic transmission
                                        is-aregulation of synaptic plasticity
                                                is-along term synaptic depression +
                                                is-along-term synaptic potentiation +
                                                is-anegative regulation of synaptic plasticity [GO:0031914] (4 genes, 4 annotations)
                                                        is-anegative regulation of synaptic metaplasticity
                                                is-apositive regulation of synaptic plasticity +
                                                is-aregulation of long term synaptic depression +
                                                is-aregulation of long-term synaptic potentiation +
                                                is-aregulation of neuronal synaptic plasticity +
                                                is-aregulation of synaptic metaplasticity +
                                                is-aregulation of synaptic plasticity by chemical substance +
                                                is-ashort-term synaptic potentiation


obsolete Gene_Ontology
        is-abiological_process
                is-asignaling
                        regulatesregulation of signaling
                                is-amodulation of synaptic transmission
                                        is-aregulation of synaptic plasticity
                                                is-along term synaptic depression +
                                                is-along-term synaptic potentiation +
                                                is-anegative regulation of synaptic plasticity [GO:0031914] (4 genes, 4 annotations)
                                                        is-anegative regulation of synaptic metaplasticity
                                                is-apositive regulation of synaptic plasticity +
                                                is-aregulation of long term synaptic depression +
                                                is-aregulation of long-term synaptic potentiation +
                                                is-aregulation of neuronal synaptic plasticity +
                                                is-aregulation of synaptic metaplasticity +
                                                is-aregulation of synaptic plasticity by chemical substance +
                                                is-ashort-term synaptic potentiation


obsolete Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                is-acell-cell signaling
                                        is-asynaptic signaling
                                                is-atrans-synaptic signaling
                                                        is-aanterograde trans-synaptic signaling
                                                                is-achemical synaptic transmission
                                                                        regulatesmodulation of synaptic transmission
                                                                                is-aregulation of synaptic plasticity
                                                                                        is-along term synaptic depression +
                                                                                        is-along-term synaptic potentiation +
                                                                                        is-anegative regulation of synaptic plasticity [GO:0031914] (4 genes, 4 annotations)
                                                                                                is-anegative regulation of synaptic metaplasticity
                                                                                        is-apositive regulation of synaptic plasticity +
                                                                                        is-aregulation of long term synaptic depression +
                                                                                        is-aregulation of long-term synaptic potentiation +
                                                                                        is-aregulation of neuronal synaptic plasticity +
                                                                                        is-aregulation of synaptic metaplasticity +
                                                                                        is-aregulation of synaptic plasticity by chemical substance +
                                                                                        is-ashort-term synaptic potentiation


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                is-acell-cell signaling
                                        is-asynaptic signaling
                                                is-atrans-synaptic signaling
                                                        is-aanterograde trans-synaptic signaling
                                                                is-achemical synaptic transmission
                                                                        regulatesmodulation of synaptic transmission
                                                                                is-aregulation of synaptic plasticity
                                                                                        is-along term synaptic depression +
                                                                                        is-along-term synaptic potentiation +
                                                                                        is-anegative regulation of synaptic plasticity [GO:0031914] (4 genes, 4 annotations)
                                                                                                is-anegative regulation of synaptic metaplasticity
                                                                                        is-apositive regulation of synaptic plasticity +
                                                                                        is-aregulation of long term synaptic depression +
                                                                                        is-aregulation of long-term synaptic potentiation +
                                                                                        is-aregulation of neuronal synaptic plasticity +
                                                                                        is-aregulation of synaptic metaplasticity +
                                                                                        is-aregulation of synaptic plasticity by chemical substance +
                                                                                        is-ashort-term synaptic potentiation


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        is-acell-cell signaling
                                                is-asynaptic signaling
                                                        is-atrans-synaptic signaling
                                                                is-aanterograde trans-synaptic signaling
                                                                        is-achemical synaptic transmission
                                                                                regulatesmodulation of synaptic transmission
                                                                                        is-aregulation of synaptic plasticity
                                                                                                is-along term synaptic depression +
                                                                                                is-along-term synaptic potentiation +
                                                                                                is-anegative regulation of synaptic plasticity [GO:0031914] (4 genes, 4 annotations)
                                                                                                        is-anegative regulation of synaptic metaplasticity
                                                                                                is-apositive regulation of synaptic plasticity +
                                                                                                is-aregulation of long term synaptic depression +
                                                                                                is-aregulation of long-term synaptic potentiation +
                                                                                                is-aregulation of neuronal synaptic plasticity +
                                                                                                is-aregulation of synaptic metaplasticity +
                                                                                                is-aregulation of synaptic plasticity by chemical substance +
                                                                                                is-ashort-term synaptic potentiation


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        regulatesregulation of cell communication
                                                is-amodulation of synaptic transmission
                                                        is-aregulation of synaptic plasticity
                                                                is-along term synaptic depression +
                                                                is-along-term synaptic potentiation +
                                                                is-anegative regulation of synaptic plasticity [GO:0031914] (4 genes, 4 annotations)
                                                                        is-anegative regulation of synaptic metaplasticity
                                                                is-apositive regulation of synaptic plasticity +
                                                                is-aregulation of long term synaptic depression +
                                                                is-aregulation of long-term synaptic potentiation +
                                                                is-aregulation of neuronal synaptic plasticity +
                                                                is-aregulation of synaptic metaplasticity +
                                                                is-aregulation of synaptic plasticity by chemical substance +
                                                                is-ashort-term synaptic potentiation


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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory