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All mouse models of psychotic disorder with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | schizophrenia | \Akt1tm1Mbb/\Akt1tm1Mbb | involves: 129P2/OlaHsd * C57BL/6 | J:185487 | View | |||
| schizophrenia | \Chrna7tm1Bay/\Chrna7tm1Bay | B6.129S7-Chrna7tm1Bay/J | J:214099 | View | ||||
| schizophrenia | \Disc1m1H/\Disc1m1H | B6N.C(C3H)-Disc1m1H | J:229661 | View | ||||
| schizophrenia | \Disc1Rgsc1390/\Disc1Rgsc1390 | B6.Cg-Disc1Rgsc1390 | J:120634 | View | ||||
| schizophrenia | \Disc1tm1(DISC1/DISC1FP1,DISC1FP1/DISC1,DISC1)Xzho/\Disc1del | 129S2/SvPasCrl-Disc1del Disc1tm1(DISC1/DISC1FP1,DISC1FP1/DISC1,DISC1)Xzho | J:214737 | View | ||||
| schizophrenia | \Disc1tm1Kara/\Disc1+ | B6.129S6-Disc1tm1Kara | J:107244 | View | ||||
| schizophrenia | \Disc1tm1Kara/\Disc1tm1Kara | B6.129S6-Disc1tm1Kara | J:107244 | View | ||||
| schizophrenia | \Dtnbp1sdy/\Dtnbp1sdy | B6J.D2-Dtnbp1sdy | J:197066, J:223954 | View | ||||
| schizophrenia | \Dtnbp1sdy/\Dtnbp1sdy | DBA/2J-Dtnbp1sdy/J | J:143912 | View | ||||
| schizophrenia |
\Ncstntm1.1Sud/\Ncstntm1.1Sud \Olig1tm1(cre)Rth/\Olig1+ |
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ | J:234705 | View | ||||
| schizophrenia | \Tg(Camk2a-ESR1/Disc1*)2698.1Sva/0 | involves: C57BL/6 * C57BL/6NTac | J:127235 | View | ||||
| schizophrenia | \Tg(Disc1/EGFP)M19Sshe/0 | involves: C57BL/6JCrl * CBA/CaCrl | J:143557 | View | ||||
| | schizoaffective disorder | \Gria1tm1Rsp/\Gria1tm1Rsp | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:167264 | View | |||
| schizoaffective disorder | \Gria1tm1Rsp/\Gria1tm1Rsp | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J | J:167264 | View | ||||
| schizophrenia | \Avpr1atm1Dgen/\Avpr1atm1Dgen | involves: 129P2/OlaHsd * C57BL/6 | J:101679 | View | ||||
| schizophrenia | \Bace1tm1Pcw/\Bace1tm1Pcw | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:133643 | View | ||||
| schizophrenia | \Chst3tm1Dgen/\Chst3tm1Dgen | involves: 129P2/OlaHsd * C57BL/6 | J:101679 | View | ||||
| schizophrenia | \ckr/\ckr | involves: C3H/HeRos * C57BL/10Ros | J:87399 | View | ||||
| schizophrenia | \Cplx2tm1Bros/\Cplx2tm1Bros | B6NCrl.Cg-Cplx2tm1Bros | J:175056 | View | ||||
| schizophrenia | \Csmd1tm1Lex/\Csmd1tm1Lex | involves: 129S5/SvEvBrd * C57BL/6NTac | J:209700 | View | ||||
| schizophrenia | \Ctsctm1Dgen/\Ctsctm1Dgen | involves: 129P2/OlaHsd * C57BL/6 | J:101679 | View | ||||
| schizophrenia | \Grin1tm1Bhk/\Grin1tm1Bhk | involves: 129P2/OlaHsd * C57BL/6 * DBA/2 | J:57125 | View | ||||
| schizophrenia | \Grm5tm1Rod/\Grm5tm1Rod | B6.129-Grm5tm1Rod | J:268239 | View | ||||
| schizophrenia | \Hivep2tm1Sis/\Hivep2tm1Sis | either: (involves: BALB/cA * C57BL/6NCrlj * CBA/JNCrlj) or (involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj) | J:263351 | View | ||||
| schizophrenia | \Hivep2tm1Sis/\Hivep2tm1Sis | involves: C57BL/6NCrlj * CBA/JNCrlj | J:271912 | View | ||||
| schizophrenia | \Kif3btm1Noh/\Kif3b+ | involves: 129S4/SvJae * C57BL/6J | J:286227 | View | ||||
| schizophrenia | \Lrrtm1tm1.1Jaru/\Lrrtm1tm1.1Jaru | involves: C57BL/6 * C57BL/6J | J:174350 | View | ||||
| schizophrenia | \Map2k7tm1Pngr/\Map2k7+ | involves: 129P2/OlaHsd * C57BL/6J | J:188339 | View | ||||
| schizophrenia | \Map6tm1Job/\Map6+ | involves: 129S2/SvPas * C57BL/6 | J:225083 | View | ||||
| schizophrenia | \Map6tm1Job/\Map6tm1Job | either: 129S2/SvPas or (involves: 129S2/SvPas * BALB/c) | J:79099 | View | ||||
| schizophrenia | \Map6tm1Job/\Map6tm1Job | involves: 129S2/SvPas * C57BL/6 | J:225083 | View | ||||
| schizophrenia | \Mdktm1Tmu/\Mdktm1Tmu | B6.129S2-Mdktm1Tmu | J:151029 | View | ||||
| schizophrenia | \Nlgn2tm1.1Gchn/\Nlgn2tm1.1Gchn | involves: 129S/SvEv * C57BL/6J | J:272181 | View | ||||
| schizophrenia | \Nr4a2tm1Tpe/\Nr4a2+ | B6.129P2-Nr4a2tm1Tpe | J:147544 | View | ||||
| schizophrenia | \Nrg1tm2Zhou/\Nrg1+ | involves: 129S4/SvJae * C57BL/6 | J:81106 | View | ||||
| schizophrenia | \Nrg3tm1.1Plet/\Nrg3tm1.1Plet | involves: C57BL/6 | J:270199 | View | ||||
| schizophrenia | \Nrxn1tm1Sud/\Nrxn1tm1Sud | involves: 129 * C57BL/6 | J:153748 | View | ||||
| schizophrenia |
\Pdgfrbtm1Msas/\Pdgfrbtm1Msas \Tg(Nes-cre)1Nogu/0 |
B6J.Cg-Pdgfrbtm1Msas Tg(Nes-cre)1Nogu | J:229179 | View | ||||
| schizophrenia | \Plcb1tm1Hssh/\Plcb1tm1Hssh | involves: 129/Sv * C57BL/6 | J:151070 | View | ||||
| schizophrenia | \Pparaem1Tyrb/\Pparaem1Tyrb | C57BL/6J-Pparaem1Tyrb | J:313946 | View | ||||
| schizophrenia | \Ppm1gtm1Dgen/\Ppm1g+ | involves: 129P2/OlaHsd * C57BL/6 | J:101679 | View | ||||
| schizophrenia |
\Ppp3r1tm1Stl/\Ppp3r1tm1Stl \Tg(Camk2a-cre)CW2Stl/0 |
C57BL/6-Ppp3r1tm1Stl Tg(Camk2a-cre)CW2Stl | J:73203, J:84640 | View | ||||
| schizophrenia | \Relnrl/\Reln+ | B6.Cg-Relnrl | J:223944 | View | ||||
| schizophrenia | \Relnrl/\Reln+ | B6C3Fe a/a-Relnrl/J | J:107996 | View | ||||
| schizophrenia | \Setd1aem1Yzhg/\Setd1a+ | B6.Cg-Setd1aem1Yzhg | J:328716 | View | ||||
| schizophrenia | \Shank3tm4.1Gfng/\Shank3tm4.1Gfng | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:230887 | View | ||||
| schizophrenia | \Slc6a1tm1Mlit/\Slc6a1tm1Mlit | B6.129S1-Slc6a1tm1Mlit | J:204368 | View | ||||
| schizophrenia | \Slc6a3tm1Mca/\Slc6a3tm1Mca | involves: 129P2/OlaHsd | J:31328 | View | ||||
| schizophrenia | \Snap25Bdr/\Snap25+ | involves: BALB/cAnNCrl | J:119733 | View | ||||
| schizophrenia | \Sp4tm3(Sp4)Krc/\Sp4tm3(Sp4)Krc | involves: 129S1/Sv * 129X1/SvJ * Black Swiss | J:163637 | View | ||||
| schizophrenia | \Srgap3tm1.1Zi/\Srgap3tm1.1Zi | B6.129(SJL)-Srgap3tm1.1Zi | J:192388 | View | ||||
| schizophrenia | \Srrrgsc1872/\Srrrgsc1872 | C57BL/6JJcl-Srrrgsc1872 | J:151337 | View | ||||
| schizophrenia | \Srrtm1.2Jtc/\Srrtm1.2Jtc | involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 | J:158266 | View | ||||
| schizophrenia | \Syngap1tm1Rlh/\Syngap1+ | involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J | J:194146 | View | ||||
| schizophrenia | \Taar1tm1Tdw/\Taar1tm1Tdw | involves: 129S1/Sv * C57BL/6J | J:141501 | View | ||||
| schizophrenia | \Tg(Camk2a-Magi2)1Shlee/? | C57BL/6J-Tg(Camk2a-Magi2)1Shlee | J:218971 | View | ||||
| schizophrenia |
\Tg(Camk2a-tTA)1Mmay/0 \Tg(tetO-Gnas)1593Mpke/0 |
B6.Cg-Tg(Camk2a-tTA)1Mmay Tg(tetO-Gnas)1593Mpke | J:166114 | View | ||||
| schizophrenia | \Tg(Thy1-Tcf4)1Mjro/0 | involves: C57BL/6N * FVB/N | J:197081 | View | ||||
| schizophrenia | \YwhazGt(OST432062)Lex/\YwhazGt(OST432062)Lex | either: B6.129S5-YwhazGt(OST432062)Lex or C.129S5-YwhazGt(OST432062)Lex or (involves: 129S5/SvEvBrd * 129T2/SvEmsWehi)) | J:217297 | View | ||||
| schizophrenia | \Zfp521tm1Nohk/\Zfp521tm1Nohk | B6J.Cg-Zfp521tm1Nohk | J:214267 | View | ||||
| schizophrenia | \Zfp804aem1Yqd/\Zfp804aem1Yqd | involves: C57BL/6 * FVB/N | J:312498 | View | ||||
| schizophrenia | \Zic2tm1Jaru/\Zic2+ | involves: 129S4/SvJae * C57BL/6J | J:174352 | View | ||||
| | schizophrenia | \Del(16Dgcr2-Hira)3Aam/\+ | involves: 129S7/SvEvBrd * C57BL/6J | J:158957 | View | |||
| Transgenes and Other Mutations | schizophrenia | \Tg(Camk2a-DISC1)10Asaw/0 | C57BL/6-Tg(Camk2a-DISC1)10Asaw | J:124683, J:194985 | View | |||
| schizophrenia | \Tg(Camk2a-DISC1)37Asaw/0 | C57BL/6-Tg(Camk2a-DISC1)37Asaw | J:124683, J:194985 | View | ||||
| schizophrenia | \Tg(Camk2a-DISC1)37Asaw/\Tg(Camk2a-DISC1)37Asaw | C57BL/6-Tg(Camk2a-DISC1)37Asaw | J:194985 | View | ||||
| schizophrenia |
\Tg(Eno2tTA)5030Nes/0 \Tg(tetO-NRG1_i4)6Ajla/0 |
involves: C57BL/6 * C57BL/6J * SJL | J:231737 | View | ||||
| schizophrenia |
\Tg(GFAP-tTA)6Hyms/0 \Tg(tetO-HMOX1)6Hyms/0 |
involves: FVB/N | J:186620 | View | ||||
| schizophrenia 9 |
\Tg(Camk2a-tTA)1Mmay/0 \Tg(tetO-DISC1*)1001Plet/0 |
involves: C57BL/6 * CBA * SJL | J:146881 | View | ||||
| schizophrenia 9 |
\Tg(tetO-DISC1*)70Plet/0 \Tg(Camk2a-tTA)1Mmay/0 |
involves: C57BL/6 * CBA * SJL | J:146881 | View | ||||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | schizophrenia | \Csmd1tm1Lex/\Csmd1tm1Lex | B6;129S5-Csmd1tm1Lex/Mmucd | J:194991 | View | |||
| schizophrenia | \Rtn4rrgsc1836/\Rtn4rrgsc1836 | C57BL/6JJcl-Rtn4rrgsc1836 | J:176996 | View | ||||
| schizophrenia | \Rtn4rtm1Gogo/\Rtn4rtm1Gogo | involves: 129 * C57BL/6J | J:130368 | View | ||||