pancreatic carcinoma Disease Ontology Browser

Disease Ontology Browser

pancreatic carcinoma (DOID:4905)
Alliance: disease page
Synonyms: carcinoma of pancreas; exocrine cancer; Exocrine pancreas carcinoma; Pancreatic carcinoma, familial
Alt IDs: OMIM:260350, EFO:0002618, NCI:C3850, UMLS_CUI:C0235974
Definition: A pancreas cancer that derives_from epithelial cells located_in the exocrine pancreas.

Term Browser
Genes (40)
Models (45)

Disease References using Mouse Models (87)

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Gene: Kras

Allelic Composition	Genetic Background	Reference	Phenotypes
\Krastm1Bbd/\Kras+ \Trp53tm1Brd/\Trp53+ \Tg(Cela1-tTA)#Eps/? \Tg(tetO-cre)3Jig/?	involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * FVB/N	J:119988	View
\Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/\Gt(ROSA)26Sor+ \Ptf1atm1.1(cre)Cvw/\Ptf1a+ \Tg(tetO-Kras*G12D)#Rdp/0 \Trp53tm1Brn/\Trp53+	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N	J:186194	View
\Krastm1Bbd/\Krastm1Bbd \Tg(Cela1-tTA)#Eps/? \Tg(tetO-cre)3Jig/?	involves: 129S1/Sv * 129X1/SvJ * FVB/N	J:119988	View
\Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/\Gt(ROSA)26Sor+ \Ptf1atm1.1(cre)Cvw/\Ptf1a+ \Tg(tetO-Kras*G12D)#Rdp/0 \Trp53tm1Brn/\Trp53tm1Brn	involves: 129P2/OlaHsd * 129S/Sv * 129X1/SvJ * C57BL/6 * FVB/N	J:186194	View
\Krastm4Tyj/\Kras+ \Ptf1atm1.1(cre)Cvw/\Ptf1a+ \Tg(MUC1)79.24Gend/0	B6.Cg-Kras^tm4Tyj Ptf1a^{tm1.1(cre)Cvw} Tg(MUC1)79.24Gend	J:234412	View
\Krastm4Tyj/\Kras+ \Tg(Pdx1-cre)6Tuv/0 \Trp53tm1Gev/\Trp53tm1Gev	involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB/N	J:220300	View
\Krastm4Tyj/\Kras+ \Tg(CAG-Bgeo,-tsA58T)T26Ichi/0 \Tg(Pdx1-cre)6Tuv/0	involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB/N	J:214846	View
\Brca2tm1Brn/\Brca2tm1Cam \Krastm4Tyj/\Kras+ \Trp53tm3Tyj/\Trp53+ \Tg(Pdx1-cre)6Tuv/0	involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB/N	J:166678	View
\Krastm4Tyj/\Kras+ \Ptf1atm1.1(cre)Cvw/\Ptf1a+	involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ	J:87973	View
\Krastm4Tyj/\Kras+ \Ptentm1Hwu/\Pten+ \Tg(Pdx1-cre)89.1Dam/0	involves: 129S4/SvJae * BALB/c * C57BL/6	J:164210	View
\Krastm4Tyj/\Kras+ \Ptentm1Hwu/\Ptentm1Hwu \Tg(Pdx1-cre)89.1Dam/0	involves: 129S4/SvJae * BALB/c * C57BL/6 * CBA	J:164210	View
\Cdkn2atm4Rdp/\Cdkn2atm4Rdp \Krastm4Tyj/\Kras+ \Tg(Pdx1-cre)89.1Dam/0	involves: 129S4/SvJae * C57BL/6 * CBA	J:187012	View
\Krastm4Tyj/\Kras+ \Tg(Pdx1-cre)6Tuv/?	involves: 129S4/SvJae * FVB/N	J:87973	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Gene: Myc

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(Ela1-Myc)158Bri/0	involves: C57BL/6 * SJL	J:76992	View
\Tg(Ela1-Myc)159Bri/0	involves: C57BL/6 * SJL	J:76992	View
\Tg(Ela1-Myc)160Bri/0	involves: C57BL/6 * SJL	J:76992	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Transgene: Tg(Cela1-luc,Cela1-TAg)#Nzh

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(Cela1-luc,Cela1-TAg)#Nzh/0	involves: FVB/N	J:207960	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Transgene: Tg(Ela1-Myc)158Bri

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(Ela1-Myc)158Bri/0	involves: C57BL/6 * SJL	J:76992	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Transgene: Tg(Ela1-Myc)159Bri

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(Ela1-Myc)159Bri/0	involves: C57BL/6 * SJL	J:76992	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Transgene: Tg(Ela1-Myc)160Bri

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(Ela1-Myc)160Bri/0	involves: C57BL/6 * SJL	J:76992	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Transgene: Tg(Ela1-TAg)18Bri

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(Ela1-TAg)18Bri/0	involves: C57BL/6 * SJL	J:76995	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Transgene: Tg(Ela1-TAg)19Bri

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(Ela1-TAg)19Bri/0	involves: C57BL/6 * SJL	J:76995	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Transgene: Tg(Ins2-Tag*,-flpe)#Gne

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(Ins2-Tag*,-flpe)#Gne/0	involves: C57BL/6J	J:187012	View
\Tg(Ins2-Tag*,-flpe)#Gne/0	Not Specified	J:188693	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Transgene: Tg(RIP1-Tag)2Dh

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(RIP1-Tag)2Dh/0	involves: C57BL/6J * DBA/2J	J:50695	View
\Bcl2l1tm1.1Mam/\Bcl2l1tm1.1Mam \Tg(Ins2-cre)25Mgn/0 \Tg(RIP1-Tag)2Dh/0	involves: 129S6/SvEvTac * C57BL/6 * DBA	J:146436	View
\Bcl2l1tm1.1Mam/\Bcl2l1tm1.1Mam \Tg(RIP1-Tag)2Dh/0	involves: 129S6/SvEvTac * C57BL/6 * DBA	J:146436	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Transgene: Tg(RIR-Tag)87Dh

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(RIR-Tag)87Dh/0	involves: C57BL/6J * DBA/2J	J:50695	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Transgene: Tg(tetO-MYC)36Bop

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(CAG-Bgeo,-tTA,-EGFP)2A11Kuw/0 \Tg(Pdx1-cre)6Tuv/0 \Tg(tetO-MYC)36Bop/0	involves: 129P2/OlaHsd * FVB/N	J:197052	View

Mouse Models