pancreatic carcinoma Disease Ontology Browser

Disease Ontology Browser

pancreatic carcinoma (DOID:4905)
Alliance: disease page
Synonyms: carcinoma of pancreas; exocrine cancer; Exocrine pancreas carcinoma; Pancreatic carcinoma, familial; Pancreatic carcinoma, familial
Alt IDs: OMIM:260350, EFO:0002618, MESH:C562463, NCI:C3850, UMLS_CUI:C0235974
Definition: A pancreas cancer that derives_from epithelial cells located_in the exocrine pancreas.

Term Browser
Genes (6)
Models (44)

Disease References using Mouse Models (79)

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Gene: Kras

Allelic Composition	Genetic Background	Reference	Phenotypes
Krastm1Bbd/Kras+ Trp53tm1Brd/Trp53+ Tg(Cela1-tTA)#Eps/? Tg(tetO-cre)3Jig/?	involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * FVB/N	J:119988	View
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+ Ptf1atm1.1(cre)Cvw/Ptf1a+ Tg(tetO-Kras*G12D)#Rdp/0 Trp53tm1Brn/Trp53+	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N	J:186194	View
Krastm1Bbd/Krastm1Bbd Tg(Cela1-tTA)#Eps/? Tg(tetO-cre)3Jig/?	involves: 129S1/Sv * 129X1/SvJ * FVB/N	J:119988	View
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+ Ptf1atm1.1(cre)Cvw/Ptf1a+ Tg(tetO-Kras*G12D)#Rdp/0 Trp53tm1Brn/Trp53tm1Brn	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N	J:186194	View
Krastm4Tyj/Kras+ Ptf1atm1.1(cre)Cvw/Ptf1a+ Tg(MUC1)79.24Gend/0	B6.Cg-Kras^tm4Tyj Ptf1a^{tm1.1(cre)Cvw} Tg(MUC1)79.24Gend	J:234412	View
Tg(Ela-KRASG12D)9Eps/0 Tg(Mt1-TGFBR2)AM3Epb/0	involves: C57BL/6 * FVB	J:231759	View
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+ Ptf1atm1.1(cre)Cvw/Ptf1a+ Tg(tetO-Kras2)12Hev/0 Trp53tm1Tyj/Trp53+	involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6J * FVB/N	J:184378	View
Krastm4Tyj/Kras+ Tg(CAG-Bgeo,-tsA58T)T26Ichi/0 Tg(Pdx1-cre)6Tuv/0	involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB/N	J:214846	View
Krastm4Tyj/Kras+ Ptf1atm1.1(cre)Cvw/Ptf1a+	involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ	J:87973	View
Krastm4Tyj/Kras+ Tg(Pdx1-cre)6Tuv/0 Trp53tm1Gev/Trp53tm1Gev	involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB/N	J:220300	View
Brca2tm1Brn/Brca2tm1Cam Krastm4Tyj/Kras+ Trp53tm3Tyj/Trp53+ Tg(Pdx1-cre)6Tuv/0	involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB/N	J:166678	View
Krastm4Tyj/Kras+ Ptentm1Hwu/Pten+ Tg(Pdx1-cre)89.1Dam/0	involves: 129S4/SvJae * BALB/c * C57BL/6	J:164210	View
Krastm4Tyj/Kras+ Ptentm1Hwu/Ptentm1Hwu Tg(Pdx1-cre)89.1Dam/0	involves: 129S4/SvJae * BALB/c * C57BL/6 * CBA	J:164210	View
Cdkn2atm4Rdp/Cdkn2atm4Rdp Krastm4Tyj/Kras+ Tg(Pdx1-cre)89.1Dam/0	involves: 129S4/SvJae * C57BL/6 * CBA	J:187012	View
Krastm4Tyj/Kras+ Tg(Pdx1-cre)6Tuv/?	involves: 129S4/SvJae * FVB/N	J:87973	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Gene: Myc

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Ela1-Myc)158Bri/0	involves: C57BL/6 * SJL	J:76992	View
Tg(Ela1-Myc)159Bri/0	involves: C57BL/6 * SJL	J:76992	View
Tg(Ela1-Myc)160Bri/0	involves: C57BL/6 * SJL	J:76992	View
Tg(CAG-Bgeo,-tTA,-EGFP)2A11Kuw/0 Tg(Pdx1-cre)6Tuv/0 Tg(tetO-MYC)36Bop/0	involves: 129P2/OlaHsd * FVB/N	J:197052	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma

Allelic Composition	Genetic Background	Reference	Phenotypes
Krastm1Bbd/Kras+ Trp53tm1Brd/Trp53+ Tg(Cela1-tTA)#Eps/? Tg(tetO-cre)3Jig/?	involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * FVB/N	J:119988	View
Rb1tm2Brn/Rb1tm2Brn Trp53tm1Brn/Trp53tm1Brn Tg(Ren-cre)#Kwg/0	involves: 129 * 129P2/OlaHsd	J:216559	View
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+ Ptf1atm1.1(cre)Cvw/Ptf1a+ Tg(tetO-Kras*G12D)#Rdp/0 Trp53tm1Brn/Trp53+	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N	J:186194	View
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+ Ptf1atm1.1(cre)Cvw/Ptf1a+ Tg(tetO-Kras*G12D)#Rdp/0 Trp53tm1Brn/Trp53tm1Brn	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N	J:186194	View
Tg(Ela1-Tgfa)150Bri/0 Trp53tm1Tyj/Trp53+	involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL	J:67389	View
Tg(Ela1-Tgfa)150Bri/0 Trp53tm1Tyj/Trp53tm1Tyj	involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL	J:67389	View
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+ Ptf1atm1.1(cre)Cvw/Ptf1a+ Tg(tetO-Kras2)12Hev/0 Trp53tm1Tyj/Trp53+	involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6J * FVB/N	J:184378	View
Krastm4Tyj/Kras+ Tg(Pdx1-cre)6Tuv/0 Trp53tm1Gev/Trp53tm1Gev	involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB/N	J:220300	View
Brca2tm1Brn/Brca2tm1Cam Krastm4Tyj/Kras+ Trp53tm3Tyj/Trp53+ Tg(Pdx1-cre)6Tuv/0	involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB/N	J:166678	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Transgene: Tg(Cela1-luc,Cela1-TAg)#Nzh

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Cela1-luc,Cela1-TAg)#Nzh/0	involves: FVB/N	J:207960	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Transgene: Tg(Ela1-Myc)158Bri

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Ela1-Myc)158Bri/0	involves: C57BL/6 * SJL	J:76992	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Transgene: Tg(Ela1-Myc)159Bri

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Ela1-Myc)159Bri/0	involves: C57BL/6 * SJL	J:76992	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Transgene: Tg(Ela1-Myc)160Bri

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Ela1-Myc)160Bri/0	involves: C57BL/6 * SJL	J:76992	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Transgene: Tg(Ela1-TAg)18Bri

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Ela1-TAg)18Bri/0	involves: C57BL/6 * SJL	J:76995	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Transgene: Tg(Ela1-TAg)19Bri

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Ela1-TAg)19Bri/0	involves: C57BL/6 * SJL	J:76995	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Transgene: Tg(Ins2-Tag*,-flpe)#Gne

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Ins2-Tag*,-flpe)#Gne/0	involves: C57BL/6J	J:187012	View
Tg(Ins2-Tag*,-flpe)#Gne/0	Not Specified	J:188693	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Transgene: Tg(RIP1-Tag)2Dh

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(RIP1-Tag)2Dh/0	involves: C57BL/6J * DBA/2J	J:50695	View
Bcl2l1tm1.1Mam/Bcl2l1tm1.1Mam Tg(RIP1-Tag)2Dh/0	involves: 129S6/SvEvTac * C57BL/6 * DBA	J:146436	View
Bcl2l1tm1.1Mam/Bcl2l1tm1.1Mam Tg(Ins2-cre)25Mgn/0 Tg(RIP1-Tag)2Dh/0	involves: 129S6/SvEvTac * C57BL/6 * DBA	J:146436	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Transgene: Tg(RIR-Tag)87Dh

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(RIR-Tag)87Dh/0	involves: C57BL/6J * DBA/2J	J:50695	View

Mouse Models

Human Disease Modeled: pancreatic carcinoma
Associated Mouse Transgene: Tg(tetO-MYC)36Bop

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(CAG-Bgeo,-tTA,-EGFP)2A11Kuw/0 Tg(Pdx1-cre)6Tuv/0 Tg(tetO-MYC)36Bop/0	involves: 129P2/OlaHsd * FVB/N	J:197052	View

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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