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Human Disease and Mouse Model Detail
Human Disease Pancreatic Cancer
OMIM ID: 260350
Synonyms Pancreatic Acinar Carcinoma; Pancreatic Cancer; Pancreatic Carcinoma
View all models View ALL (29) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Gene is associated with the disease in this species
      Mouse Homologs Human Homologs Mouse Models Mouse : Human
Homology Class
     Kras* KRAS* View 15 models 1:1 Homology
Trp53* TP53* View 8 models 1:1 Homology
     Brca2* BRCA2 View 1 model 1:1 Homology
Cdkn2a* CDKN2A View 5 models 1:1 Homology
Pten* PTEN View 2 models 1:1 Homology
     Smad4 SMAD4*   1:1 Homology
Stk11 STK11*   1:1 Homology
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Tg(CAG-Bgeo,-tsA58T)T26Ichi View 1 model
  Tg(CAG-Bgeo,-tTA,-EGFP)2A11Kuw View 1 model
  Tg(Cela1-luc,Cela1-TAg)#Nzh View 1 model
  Tg(Cela1-tTA)#Eps View 2 models
  Tg(Ela1-Myc)158Bri View 1 model
  Tg(Ela1-Myc)159Bri View 1 model
  Tg(Ela1-Myc)160Bri View 1 model
  Tg(Ela1-TAg)18Bri View 1 model
  Tg(Ela1-TAg)19Bri View 1 model
  Tg(RIP1-Tag)2Dh View 3 models
  Tg(RIR-Tag)87Dh View 1 model
  Tg(tetO-Kras2)12Hev View 1 model
  Tg(TetO-MYC)36Bop View 1 model
References Disease References using Mouse Models (35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.20
The Jackson Laboratory