Aldh1a2tm1Soc/Aldh1a2tm2Soc
Isl1tm1(cre)Tmj/Isl1+
involves: 129X1/SvJ
|
abnormal motor neuron innervation pattern |
J:112635
|
|
decreased motor neuron number |
J:112635
|
Bcortm1.1Vjba/Bcor+
Isl1tm1(cre)Sev/Isl1+
involves: 129S1/Sv
|
persistent truncus arteriosus |
J:296645
|
|
preweaning lethality, incomplete penetrance |
J:296645
|
Bcortm1.1Vjba/Y
Isl1tm1(cre)Sev/Isl1+
involves: 129S1/Sv
|
abnormal aortic arch morphology |
J:296645
|
|
lethality throughout fetal growth and development |
J:296645
|
|
perimembraneous ventricular septal defect |
J:296645
|
|
persistent truncus arteriosus |
J:296645
|
|
preweaning lethality, complete penetrance |
J:296645
|
|
syndactyly |
J:296645
|
Bmp4tm4Blh/Bmp4tm4Blh
Isl1tm1(cre)Sev/Isl1+
involves: 129 * 129S6/SvEvTac
|
abnormal embryonic cloaca development |
J:192045
|
|
abnormal external female genitalia morphology |
J:192045
|
|
abnormal fibula morphology |
J:192045
|
|
abnormal hindlimb bud morphology |
J:192045
|
|
abnormal limb development |
J:192045
|
|
abnormal renal/urinary system morphology |
J:192045
|
|
absent urinary bladder |
J:192045
|
|
anal stenosis |
J:192045
|
|
external male genitalia hypoplasia |
J:192045
|
|
renal hypoplasia |
J:192045
|
|
sirenomelia |
J:192045
|
Bmpr1atm2.1Bhr/Bmpr1atm2.2Bhr
Isl1tm1(cre)Sev/Isl1+
involves: 129S4/SvJae * 129S7/SvEvBrd
|
abnormal cardiomyocyte apoptosis |
J:107396
|
|
abnormal fetal cardiomyocyte proliferation |
J:107396
|
|
abnormal hindlimb bud morphology |
J:107396
|
|
abnormal hindlimb morphology |
J:107396
|
|
decreased cell proliferation |
J:107396
|
|
embryonic lethality during organogenesis, complete penetrance |
J:107396
|
|
persistent truncus arteriosus |
J:107396
|
|
small hindlimb buds |
J:107396
|
Brsk2tm2.1Jrs/Brsk2tm2.1Jrs
Isl1tm1(cre)Tmj/Isl1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
|
abnormal axon extension |
J:201695
|
|
abnormal proprioceptive neuron morphology |
J:201695
|
|
abnormal sensory neuron innervation pattern |
J:201695
|
|
absent gastric milk in neonates |
J:201695
|
|
bradykinesia |
J:201695
|
|
neonatal lethality, incomplete penetrance |
J:201695
|
|
normal
nervous system phenotype |
J:201695
|
Casz1tm1.1Flc/Casz1tm1.1Flc
Isl1tm1(cre)Tmj/Isl1+
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL
|
abnormal heart right ventricle morphology |
J:221324
|
|
abnormal heart shape |
J:221324
|
|
decreased mitotic index |
J:221324
|
|
heart right ventricle hypoplasia |
J:221324
|
|
lethality throughout fetal growth and development, complete penetrance |
J:221324
|
Dll4tm1Frad/Dll4+
Isl1tm1(cre)Tmj/Isl1+
involves: 129S1/Sv * 129X1/SvJ
|
abnormal cardiac outflow tract development |
J:308916
|
|
abnormal pulmonary valve morphology |
J:308916
|
|
double outlet right ventricle |
J:308916
|
|
overriding aortic valve |
J:308916
|
|
ventricular septal defect |
J:308916
|
Dvl3tm1Awb/Dvl3tm1Awb
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Isl1tm1(cre)Sev/Isl1+
involves: 129S4/SvJaeSor * 129S6/SvEvTac * Black Swiss
|
normal
cardiovascular system phenotype |
J:142392
|
Epha4tm1.1Bzh/Epha4tm1.1Bzh
Isl1tm1(cre)Sev/Isl1+
Tg(Hlxb9-GFP)1Tmj/0
involves: 129S/Sv * Black Swiss * C57BL/6J * CD-1 * FVB/N
|
abnormal abducens nerve morphology |
J:243785
|
|
abnormal innervation |
J:243785
|
Etv1tm1Wds/Etv1tm1.1Wds
Isl1tm1(cre)Tmj/Isl1+
involves: 129X1/SvJ
|
abnormal proprioceptive neuron morphology |
J:83461
|
Fgf8tm1Mrc/Fgf8tm2Moon
Isl1tm1(cre)Sev/Isl1+
involves: 129S/Sv * Black Swiss * C57BL/6
|
abnormal cardiac epithelial to mesenchymal transition |
J:143444
|
|
abnormal cardiac outflow tract development |
J:143444
|
|
abnormal conotruncal ridge morphology |
J:143444
|
|
persistent truncus arteriosus |
J:143444
|
Fgf8tm2Moon/Fgf8tm1Mrc
Isl1tm1(cre)Sev/Isl1+
involves: 129S/Sv
|
abnormal heart right ventricle morphology |
J:109475
|
|
abnormal truncus arteriosus septation |
J:109475
|
|
embryonic lethality during organogenesis, incomplete penetrance |
J:109475
|
|
increased apoptosis |
J:109475
|
|
persistent truncus arteriosus |
J:109475
|
|
small pharyngeal arch |
J:109475
|
Gt(ROSA)26Sortm1(RARA*)Soc/Gt(ROSA)26Sortm1(RARA*)Soc
Isl1tm1(cre)Tmj/Isl1+
involves: 129X1/SvJ
|
decreased motor neuron number |
J:135403
|
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Isl1tm2Sev/Isl1tm2Sev
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
|
abnormal dorsal root ganglion morphology |
J:141110
|
|
abnormal sensory neuron innervation pattern |
J:141110
|
|
abnormal trigeminal ganglion morphology |
J:141110
|
|
decreased chemical nociceptive threshold |
J:141110
|
|
dorsal root ganglion hypoplasia |
J:141110
|
|
neonatal lethality, complete penetrance |
J:141110
|
Hand2tm1Dsr/Hand2tm2.1Dsr
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Isl1tm1(cre)Tmj/Isl1+
involves: 129S4/SvJaeSor * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
|
abnormal heart development |
J:169213
|
Hand2tm1Dsr/Hand2tm2.1Dsr
Isl1tm1(cre)Tmj/Isl1+
involves: 129 * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
|
abnormal cardiac outflow tract development |
J:169213
|
|
embryonic lethality during organogenesis, complete penetrance |
J:169213
|
|
heart right ventricle hypoplasia |
J:169213
|
|
increased apoptosis |
J:169213
|
Irx3tm3Hui/Irx3tm3Hui
Irx5tm3Hui/Irx5tm3Hui
Isl1tm1(cre)Sev/Isl1+
involves: 129S/Sv
|
abnormal cardiac outflow tract development |
J:189007
|
|
abnormal interatrial septum morphology |
J:189007
|
|
atrial septal defect |
J:189007
|
|
atrioventricular septal defect |
J:189007
|
|
double outlet right ventricle |
J:189007
|
|
persistent truncus arteriosus |
J:189007
|
Isl1tm1(cre)Sev/Isl1+
Pax9tm1Rbal/Pax9tm1.1Hpt
involves: 129 * C57BL/6J
|
aberrant origin of the right subclavian artery |
J:311535
|
|
abnormal common carotid artery morphology |
J:311535
|
|
normal
craniofacial phenotype |
J:311535
|
|
double outlet right ventricle |
J:311535
|
|
ectopic thymus |
J:311535
|
|
interrupted aortic arch |
J:311535
|
|
preaxial polydactyly |
J:311535
|
|
thymus hypoplasia |
J:311535
|
|
ventricular septal defect |
J:311535
|
Isl1tm1(cre)Sev/Isl1+
Msx1tm1Rilm/Msx1+
Pax9tm1Rbal/Pax9tm1.1Hpt
involves: 129 * CD-1
|
aberrant origin of the right subclavian artery |
J:311535
|
|
abnormal hyoid bone greater horn morphology |
J:311535
|
|
abnormal hyoid bone lesser horn morphology |
J:311535
|
|
abnormal hyoid bone morphology |
J:311535
|
|
abnormal inferior horn of thyroid cartilage morphology |
J:311535
|
|
abnormal superior horn of thyroid cartilage morphology |
J:311535
|
|
craniofacial phenotype |
J:311535
|
|
neonatal lethality, complete penetrance |
J:311535
|
|
preaxial polydactyly |
J:311535
|
Isl1tm1(cre)Sev/Isl1+
Juntm4Wag/Jun+
Not Specified
|
interrupted aortic arch, type b |
J:199412
|
Isl1tm1(cre)Sev/Isl1+
Tg(CAG-lacZ,-BMPR1A*,-EGFP)1Mis/0
involves: 129S7/SvEvBrd
|
atrioventricular septal defect |
J:189007
|
Isl1tm1(cre)Tmj/Isl1+
Mapttm1(Ewsr1/Etv4)Arbr/Mapt+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
|
abnormal dorsal root ganglion morphology |
J:100886
|
|
abnormal sensory neuron innervation pattern |
J:100886
|
|
abnormal sensory neuron morphology |
J:100886
|
|
decreased muscle spindle number |
J:100886
|
Isl1tm1(cre)Tmj/Isl1+
Tg(SOD1*G37R)1Dwc/0
involves: 129X1/SvJ * C57BL/6
|
axon degeneration |
J:109131
|
|
premature death |
J:109131
|
Isl1tm1(cre)Tmj/Isl1+
Shc1tm9Paw/Shc1tm9.1Paw
involves: 129S1/Sv * 129X1/SvJ
|
no abnormal phenotype detected |
J:122927
|
Isl1tm1(cre)Tmj/Isl1+
Shc1tm9Paw/Shc1tm9Paw
involves: 129S1/Sv * 129X1/SvJ
|
no abnormal phenotype detected |
J:122927
|
Isl1tm1(cre)Tmj/Isl1+
Phox2btm3.1Jbr/Phox2btm3.1Jbr
involves: 129S2/SvPas * 129X1/SvJ
|
abnormal pterygopalatine ganglion morphology |
J:157532
|
|
absent petrosal ganglion |
J:157532
|
Isl1tm1(cre)Tmj/Isl1+
Zfp503tm1Lif/Zfp503tm1Lif
Tg(CAG-cat,-EGFP)1Rbns/0
involves: 129 * 129X1/SvJ * C57BL/6 * C57BL/6J
|
abnormal dorsal striatum morphology |
J:286635
|
|
abnormal striatum morphology |
J:286635
|
|
abnormal ventral striatum morphology |
J:286635
|
Isl1tm1Gan/Isl1tm2Gan
Pou4f2tm1(ALPP)Whk/Pou4f2tm2Whk
Tg(Six3-cre)69Frty/?
involves: 129S6/SvEvTac * C57BL/6 * DBA/2
|
optic nerve hypoplasia |
J:134978
|
|
retina ganglion cell degeneration |
J:134978
|
Isl1tm1Tmj/Isl1tm1Tmj
Pou4f1tm1Et/Pou4f1tm1Et
involves: 129 * C57BL/6
|
abnormal brain development |
J:141110
|
|
embryonic growth arrest |
J:141110
|
|
embryonic lethality during organogenesis, complete penetrance |
J:141110
|
Isl1tm2Gan/Isl1tm2Gan
Pou4f2tm1(ALPP)Whk/Pou4f2tm2Whk
Tg(Six3-cre)69Frty/?
involves: 129S6/SvEvTac * C57BL/6 * DBA/2
|
optic nerve hypoplasia |
J:134978
|
|
retina ganglion cell degeneration |
J:134978
|
Juntm1Pa/Juntm4Wag
Isl1tm1(cre)Sev/Isl1+
involves: 129P2/OlaHsd * 129S/Sv * 129X1/SvJ * C57BL/6J
|
normal
cardiovascular system phenotype |
J:199412
|
|
normal
embryo phenotype |
J:199412
|
Juntm4Wag/Juntm4Wag
Isl1tm1(cre)Sev/Isl1+
involves: 129P2/OlaHsd * 129S/Sv
|
abnormal aortic valve morphology |
J:199412
|
|
abnormal cardiac outflow tract development |
J:199412
|
|
abnormal pharyngeal arch artery morphology |
J:199412
|
|
abnormal pulmonary valve cusp morphology |
J:199412
|
|
abnormal pulmonary valve morphology |
J:199412
|
|
double outlet right ventricle |
J:199412
|
|
interrupted aortic arch, type b |
J:199412
|
|
normal
mortality/aging |
J:199412
|
|
retroesophageal right subclavian artery |
J:199412
|
|
semilunar valve hyperplasia |
J:199412
|
|
ventricular septal defect |
J:199412
|
Maftm1.1Cbm/Maftm2.1Cbm
Isl1tm1(cre)Tmj/Isl1+
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * SJL
|
abnormal axon morphology |
J:181639
|
|
abnormal coat/ hair morphology |
J:181639
|
|
abnormal Meissner's corpuscle morphology |
J:181639
|
|
abnormal nervous system electrophysiology |
J:181639
|
|
abnormal pacinian corpuscle morphology |
J:181639
|
|
axon degeneration |
J:181639
|
|
decreased body weight |
J:181639
|
|
decreased nerve conduction velocity |
J:181639
|
|
decreased pacinian corpuscle number |
J:181639
|
|
impaired coordination |
J:181639
|
|
small pacinian corpuscles |
J:181639
|
Nkx2-5tm1Krc/Nkx2-5tm1Krc
Isl1tm1(cre)Sev/Isl1+
involves: 129 * C57BL/6
|
abnormal cardiac outflow tract development |
J:214093
|
|
absent heart right ventricle |
J:214093
|
|
embryonic lethality during organogenesis, complete penetrance |
J:214093
|
Nkx2-5tm1Krc/Nkx2-5tm1Krc
Isl1tm1(cre)Tmj/Isl1+
involves: 129X1/SvJ * C57BL/6
|
abnormal cardiac outflow tract development |
J:214093
|
|
abnormal conotruncal ridge morphology |
J:214093
|
|
abnormal heart right ventricle morphology |
J:214093
|
|
abnormal myocardial trabeculae morphology |
J:214093
|
|
cyanosis |
J:214093
|
|
decreased heart right ventricle size |
J:214093
|
|
double outlet right ventricle |
J:214093
|
|
heart right ventricle hypoplasia |
J:214093
|
|
perinatal lethality |
J:214093
|
|
persistent truncus arteriosus |
J:214093
|
Nrg1tm1Cbm/Nrg1tm3Cbm
Isl1tm1(cre)Tmj/Isl1+
involves: 129P2/OlaHsd * 129X1/SvJ
|
abnormal muscle spindle morphology |
J:80793
|
|
abnormal proprioceptive neuron morphology |
J:80793
|
|
decreased Schwann cell number |
J:80793
|
Phox2btm3.1Jbr/Phox2btm3.1Jbr
Isl1tm1(cre)Tmj/Isl1+
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * DBA/2
|
abnormal neuron differentiation |
J:155885
|
|
abnormal neuron physiology |
J:155885
|
|
decreased body size |
J:155885
|
|
postnatal lethality, complete penetrance |
J:155885
|
Rspo3tm1Arte/Rspo3tm1Arte
Isl1tm1(cre)Sev/Isl1+
involves: 129 * C57BL/6
|
abnormal cardiac outflow tract development |
J:214093
|
|
abnormal heart right ventricle morphology |
J:214093
|
|
blood vessel congestion |
J:214093
|
|
embryonic lethality during organogenesis, complete penetrance |
J:214093
|
|
pericardial edema |
J:214093
|
|
thin myocardium |
J:214093
|
Rspo3tm1Arte/Rspo3tm1Arte
Isl1tm1(cre)Tmj/Isl1+
involves: 129X1/SvJ * C57BL/6
|
decreased heart right ventricle size |
J:214093
|
|
double outlet right ventricle |
J:214093
|
|
lethality throughout fetal growth and development, complete penetrance |
J:214093
|
|
pericardial edema |
J:214093
|
Smotm1Amc/Smotm2Amc
Isl1tm1(cre)Sev/Isl1+
involves: 129S/Sv * 129X1/SvJ
|
abnormal aortic arch morphology |
J:110602
|
|
abnormal cardiac neural crest cell migration |
J:110602
|
|
abnormal cardiac outflow tract development |
J:110602
|
|
abnormal sixth pharyngeal arch artery morphology |
J:110602
|
|
atrial septal defect |
J:110602
|
|
perinatal lethality |
J:110602
|
|
persistent truncus arteriosus |
J:110602
|
|
right aortic arch |
J:110602
|
|
transposition of great arteries |
J:110602
|
|
ventricular septal defect |
J:110602
|
Smotm2Amc/Smotm2Amc
Isl1tm1(cre)Tmj/Isl1+
involves: 129S/Sv * 129X1/SvJ
|
abnormal blood circulation |
J:204743
|
|
abnormal heart right ventricle morphology |
J:204743
|
|
blood vessel atresia |
J:204743
|
|
persistent truncus arteriosus |
J:204743
|
Stk11tm1.1Rdp/Stk11tm1.1Rdp
Isl1tm1(cre)Tmj/Isl1+
involves: 129S6/SvEvTac * 129X1/SvJ
|
abnormal cerebral cortex morphology |
J:201695
|
|
normal
behavior/neurological phenotype |
J:201695
|
|
decreased tumor-free survival time |
J:201695
|
|
increased gastrointestinal tumor incidence |
J:201695
|
|
normal
nervous system phenotype |
J:201695
|
|
thin cerebral cortex |
J:201695
|
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