Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Smad3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SMAD3
- Mouse genes Smad3
- Rat genes Smad3
- Zfish genes smad3a,smad3b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Smad3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008013	beta-catenin binding	Smad3	IDA		Rat	PMID:20097766\|RGD:11079190
Molecular Function	GO:0043425	bHLH transcription factor binding	SMAD3	IPI	UniProtKB:Q99081	Human	PMID:21828274
Molecular Function	GO:0003682	chromatin binding	Smad3	IDA		Mouse	PMID:16619037
Molecular Function	GO:0031490	chromatin DNA binding	Smad3	IDA		Mouse	MGI:MGI:3696631\|PMID:16224064
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	SMAD3	IDA		Human	PMID:21947082
Molecular Function	GO:0070410	co-SMAD binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:8774881
Molecular Function	GO:0070410	co-SMAD binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:9111321
Molecular Function	GO:0070410	co-SMAD binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:9311995
Molecular Function	GO:0070410	co-SMAD binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:9732876
Molecular Function	GO:0005518	collagen binding	Smad3	IPI	PR:Q3U962	Mouse	PMID:14559231
Molecular Function	GO:0005518	collagen binding	Smad3	IPI	PR:P08121	Mouse	PMID:14559231
Molecular Function	GO:0005518	collagen binding	Smad3	IPI	PR:Q01149	Mouse	PMID:14559231
Molecular Function	GO:0017151	DEAD/H-box RNA helicase binding	SMAD3	IPI	UniProtKB:P17844	Human	PMID:18548003
Molecular Function	GO:0003677	DNA binding	SMAD3	IDA		Human	PMID:28467929
Molecular Function	GO:0003677	DNA binding	Smad3	IDA		Mouse	MGI:MGI:6252929\|PMID:27336669
Molecular Function	GO:0003677	DNA binding	Smad3	IDA		Rat	PMID:16959941\|RGD:1599906
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	SMAD3	IDA		Human	PMID:24378993
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	SMAD3	IMP		Human	PMID:24378993
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	SMAD3	IDA		Human	PMID:25605017
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	SMAD3	IMP		Human	PMID:26311719
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Smad3	IPI	ENSEMBL_GeneID:ENSG00000127445	Mouse	MGI:MGI:6158712\|PMID:24964035
Molecular Function	GO:0003700	DNA-binding transcription factor activity	SMAD3	IDA		Human	PMID:9111321
Molecular Function	GO:0003700	DNA-binding transcription factor activity	SMAD3	IDA		Human	PMID:10823886
Molecular Function	GO:0003700	DNA-binding transcription factor activity	SMAD3	IDA		Human	PMID:21947082
Molecular Function	GO:0003700	DNA-binding transcription factor activity	SMAD3	IDA		Human	PMID:9732876
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Smad3	IDA		Mouse	PMID:12943993
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Smad3	IDA		Rat	PMID:12702545\|RGD:1299323
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	SMAD3	IDA		Human	PMID:21947082
Molecular Function	GO:0140297	DNA-binding transcription factor binding	SMAD3	IPI	UniProtKB:O75593	Human	PMID:21828274
Molecular Function	GO:0001217	DNA-binding transcription repressor activity	SMAD3	IDA		Human	PMID:28467929
Molecular Function	GO:0003690	double-stranded DNA binding	Smad3	IDA		Mouse	PMID:15282343
Molecular Function	GO:0019899	enzyme binding	Smad3	IPI	RGD:2053	Rat	PMID:22073128\|RGD:8554355
Molecular Function	GO:0019899	enzyme binding	Smad3	IPI	UniProtKB:P27008	Rat	PMID:22073128\|RGD:8554355
Molecular Function	GO:0042802	identical protein binding	SMAD3	IPI	UniProtKB:P84022	Human	PMID:18729074
Molecular Function	GO:0042802	identical protein binding	SMAD3	IPI	UniProtKB:P84022	Human	PMID:22045334
Molecular Function	GO:0042802	identical protein binding	Smad3	IPI	PR:Q8BUN5	Mouse	PMID:21724602
Molecular Function	GO:0035259	nuclear glucocorticoid receptor binding	SMAD3	IPI	UniProtKB:P04150	Human	PMID:12902338
Molecular Function	GO:0031962	nuclear mineralocorticoid receptor binding	SMAD3	IPI	UniProtKB:P22199	Human	PMID:12902338
Molecular Function	GO:0016922	nuclear receptor binding	SMAD3	IPI	UniProtKB:P37231	Human	PMID:31023188
Molecular Function	GO:0019902	phosphatase binding	SMAD3	IPI	UniProtKB:P35813	Human	PMID:16751101
Molecular Function	GO:1990841	promoter-specific chromatin binding	Smad3	IDA		Mouse	PMID:18802055
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9WVQ1	Human	PMID:10681527
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:O00255	Human	PMID:11274402
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13573	Human	PMID:11278756
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P98082	Human	PMID:11387212
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:O95405	Human	PMID:12154125
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P12755	Human	PMID:14525983
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q8N6I1	Human	PMID:14612439
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q14511,UniProtKB:Q96J02	Human	PMID:15051726
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:O43524	Human	PMID:15084259
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:O95405	Human	PMID:15231748
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:15231748
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:15350224
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q09472	Human	PMID:15588252
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9Y2U8	Human	PMID:15647271
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q03112-1	Human	PMID:15897867
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:O92972:PRO_0000278742	Human	PMID:16007207
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q2VWA4	Human	PMID:16200078
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q93062	Human	PMID:17099224
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P84550	Human	PMID:17292623
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P12755	Human	PMID:17469184
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P12757-1	Human	PMID:17469184
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:O15397	Human	PMID:17785517
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P17844	Human	PMID:18548003
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9NRR4	Human	PMID:18548003
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9GZV5	Human	PMID:18568018
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:O00308	Human	PMID:18729074
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:18729074
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13573	Human	PMID:18729074
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q15796	Human	PMID:18729074
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q93009	Human	PMID:18729074
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9BZ29	Human	PMID:18729074
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9HAU4	Human	PMID:18729074
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P52926	Human	PMID:18832382
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P12755	Human	PMID:19032343
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P12755	Human	PMID:19049980
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13547	Human	PMID:19049980
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9HAZ2	Human	PMID:19049980
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13526	Human	PMID:19122240
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:19135894
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9H6Z4	Human	PMID:19289081
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9NYA4	Human	PMID:20061380
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P84022	Human	PMID:20129061
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q01543	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:O00308	Human	PMID:21258410
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:21297662
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9H4X1	Human	PMID:21307346
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:O43524	Human	PMID:21532621
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:21532621
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:21597466
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:O75593	Human	PMID:21828274
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9Y4E8	Human	PMID:21947082
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13501	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q15796	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q16822	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q5D1E8	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q93009	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q96EP0	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q99836	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9BYW2	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9BZL4	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9H2X0	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9Y3Q8	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:22045334
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9HAU4	Human	PMID:22045334
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P12755	Human	PMID:22442258
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:22442258
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q96PZ7	Human	PMID:22538441
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q96AC1	Human	PMID:23723426
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P08238\|UniProtKB:P0DMV8	Human	PMID:24613385
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P0DMV8,UniProtKB:Q9UNE7	Human	PMID:24613385
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9UNE7	Human	PMID:24613385
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:O15165	Human	PMID:24627487
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P50222	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q08117	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q8IXK0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q8N684	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q8WW24	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9H0M0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9H2G9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:O95405	Human	PMID:25502805
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:25502805
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P0DOE7	Human	PMID:25556234
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P10070	Human	PMID:25670079
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:O00308	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:O43186	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P50222	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q08117-2	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q8IXK0-5	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q8N5R6	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q8N684-3	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9H0M0	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9H2G9	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q64729	Human	PMID:26680585
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q16665	Human	PMID:28471448
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q14511	Human	PMID:29899023
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:O95405	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q08117	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q8N5R6	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:E9PSE9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:O75593	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P0C264	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P20618	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P46934-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q13485	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q6NX45	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q86YD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9H0M0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9H2G9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9HAU4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P17612	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P27986-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P29466-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P48730-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q06481-5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q15583	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q8WXH2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:Q9UQM7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:O95405	Human	PMID:9865696
Molecular Function	GO:0005515	protein binding	SMAD3	IPI	UniProtKB:P36896	Human	PMID:9892009
Molecular Function	GO:0005515	protein binding	Smad3	IPI	UniProtKB:P46938\|UniProtKB:P97471	Mouse	MGI:MGI:4939579\|PMID:21145499
Molecular Function	GO:0005515	protein binding	Smad3	IPI	UniProtKB:O95551	Mouse	MGI:MGI:3813431\|PMID:18039968
Molecular Function	GO:0005515	protein binding	Smad3	IPI	UniProtKB:Q8VIM5	Mouse	MGI:MGI:3696631\|PMID:16224064
Molecular Function	GO:0005515	protein binding	Smad3	IPI	UniProtKB:P97471	Mouse	MGI:MGI:3829534\|PMID:18268325
Molecular Function	GO:0005515	protein binding	Smad3	IPI	UniProtKB:P97471	Mouse	MGI:MGI:5305872\|PMID:22045334
Molecular Function	GO:0005515	protein binding	Smad3	IPI	UniProtKB:P97471	Mouse	MGI:MGI:5508709\|PMID:22442258
Molecular Function	GO:0005515	protein binding	Smad3	IPI	UniProtKB:P20263\|UniProtKB:P97471	Mouse	MGI:MGI:5315322\|PMID:22036565
Molecular Function	GO:0005515	protein binding	Smad3	IPI	UniProtKB:Q15327	Mouse	MGI:MGI:5294529\|PMID:20599664
Molecular Function	GO:0005515	protein binding	Smad3	IPI	UniProtKB:Q9DBX1	Mouse	MGI:MGI:5317995\|PMID:21990365
Molecular Function	GO:0005515	protein binding	Smad3	IPI	PR:P10085	Mouse	PMID:11711431
Molecular Function	GO:0005515	protein binding	Smad3	IPI	PR:Q62261	Mouse	PMID:12543979
Molecular Function	GO:0005515	protein binding	Smad3	IPI	PR:A7M7C7	Mouse	PMID:21937600
Molecular Function	GO:0005515	protein binding	Smad3	IPI	UniProtKB:Q6PGA9	Mouse	PMID:16619037
Molecular Function	GO:0005515	protein binding	Smad3	IPI	PR:O70477	Mouse	PMID:14764653
Molecular Function	GO:0005515	protein binding	Smad3	IPI	PR:Q61656	Mouse	PMID:15464984
Molecular Function	GO:0005515	protein binding	Smad3	IPI	PR:Q08775	Mouse	PMID:15990875
Molecular Function	GO:0005515	protein binding	Smad3	IPI	PR:P41778	Mouse	PMID:14764653
Molecular Function	GO:0005515	protein binding	Smad3	IPI	PR:Q6NZM9	Mouse	PMID:15990875
Molecular Function	GO:0005515	protein binding	Smad3	IPI	PR:O35295	Mouse	PMID:15282343
Molecular Function	GO:0005515	protein binding	Smad3	IPI	PR:O88559	Mouse	PMID:15150273
Molecular Function	GO:0005515	protein binding	Smad3	IPI	PR:P42669	Mouse	PMID:15282343
Molecular Function	GO:0005515	protein binding	Smad3	IPI	PR:Q9Z2V6	Mouse	PMID:15990875
Molecular Function	GO:0005515	protein binding	Smad3	IPI	PR:O35625	Mouse	PMID:16601693
Molecular Function	GO:0005515	protein binding	Smad3	IPI	PR:A2A935	Mouse	PMID:17467076
Molecular Function	GO:0005515	protein binding	Smad3	IPI	PR:P97471	Mouse	PMID:21724602
Molecular Function	GO:0005515	protein binding	Smad3	IPI	UniProtKB:P47196	Rat	PMID:16362038\|RGD:8553856
Molecular Function	GO:0005515	protein binding	Smad3	IPI	UniProtKB:O35740	Rat	PMID:16619037\|RGD:8554622
Molecular Function	GO:0005515	protein binding	Smad3	IPI	RGD:2401	Rat	PMID:16959941\|RGD:1599906
Molecular Function	GO:0005515	protein binding	Smad3	IPI	UniProtKB:P59595	Rat	PMID:18055455\|RGD:39458009
Molecular Function	GO:0005515	protein binding	smad3a	IPI	ZFIN:ZDB-GENE-031030-4	Zfish	PMID:16890162
Molecular Function	GO:0005515	protein binding	smad3b	IPI	ZFIN:ZDB-GENE-031030-4	Zfish	PMID:16890162
Molecular Function	GO:0042803	protein homodimerization activity	SMAD3	IPI	UniProtKB:P84022	Human	PMID:8774881
Molecular Function	GO:0019901	protein kinase binding	SMAD3	IPI	UniProtKB:Q9H2X6	Human	PMID:12874272
Molecular Function	GO:0070412	R-SMAD binding	SMAD3	IPI	UniProtKB:P84022	Human	PMID:20129061
Molecular Function	GO:0070412	R-SMAD binding	SMAD3	IPI	UniProtKB:Q15796	Human	PMID:9311995
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	SMAD3	IDA		Human	PMID:18832382
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	SMAD3	IDA		Human	PMID:21947082
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	SMAD3	IDA		Human	PMID:24378993
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	SMAD3	IDA		Human	PMID:31582430
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Smad3	IDA		Mouse	MGI:MGI:5688819\|PMID:25065622
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	SMAD3	IPI	UniProtKB:P26367	Human	PMID:17251190
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	SMAD3	IPI	UniProtKB:P01100	Human	PMID:9732876
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	SMAD3	IPI	UniProtKB:P05412	Human	PMID:9732876
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Smad3	IPI	UniProtKB:B7ZQJ9	Mouse	MGI:MGI:4399035\|PMID:11937490
Molecular Function	GO:0043565	sequence-specific DNA binding	SMAD3	IDA		Human	PMID:10823886
Molecular Function	GO:0043565	sequence-specific DNA binding	Smad3	IDA		Rat	PMID:12702545\|RGD:1299323
Molecular Function	GO:0043565	sequence-specific DNA binding	Smad3	IDA		Rat	PMID:16205635\|RGD:2300406
Molecular Function	GO:0043565	sequence-specific DNA binding	Smad3	IDA		Rat	PMID:16891311\|RGD:1625706
Molecular Function	GO:0043565	sequence-specific DNA binding	Smad3	IDA		Rat	PMID:22073128\|RGD:8554355
Molecular Function	GO:0043565	sequence-specific DNA binding	smad3a	IPI	ZFIN:ZDB-GENE-000616-6	Zfish	PMID:21159776
Molecular Function	GO:0046332	SMAD binding	Smad3	IPI	RGD:3033	Rat	PMID:16959941\|RGD:1599906
Molecular Function	GO:0032810	sterol response element binding	SMAD3	IGI	UniProtKB:P01137	Human	PMID:25605017
Molecular Function	GO:0000976	transcription cis-regulatory region binding	SMAD3	IDA		Human	PMID:9732876
Molecular Function	GO:0001223	transcription coactivator binding	SMAD3	IPI	UniProtKB:Q9ULJ6	Human	PMID:16777850
Molecular Function	GO:0005160	transforming growth factor beta receptor binding	SMAD3	IPI	UniProtKB:P36897	Human	PMID:9311995
Molecular Function	GO:0043130	ubiquitin binding	SMAD3	IDA		Human	PMID:18794808
Molecular Function	GO:0031625	ubiquitin protein ligase binding	SMAD3	IPI	UniProtKB:Q9HCE7	Human	PMID:11278251
Molecular Function	GO:0031625	ubiquitin protein ligase binding	SMAD3	IPI	UniProtKB:Q9HAU4	Human	PMID:19122240
Molecular Function	GO:0008270	zinc ion binding	SMAD3	IDA		Human	PMID:12686552
Cellular Component	GO:0000785	chromatin	SMAD3	IDA		Human	PMID:21828274
Cellular Component	GO:0005737	cytoplasm	SMAD3	IDA		Human	PMID:12446380
Cellular Component	GO:0005737	cytoplasm	SMAD3	IDA		Human	PMID:21145499
Cellular Component	GO:0005737	cytoplasm	SMAD3	IDA		Human	PMID:21947082
Cellular Component	GO:0005737	cytoplasm	SMAD3	IDA		Human	PMID:9311995
Cellular Component	GO:0005737	cytoplasm	Smad3	IDA		Mouse	MGI:MGI:5009194\|PMID:11160896
Cellular Component	GO:0005737	cytoplasm	Smad3	IDA		Mouse	MGI:MGI:4939579\|PMID:21145499
Cellular Component	GO:0005737	cytoplasm	Smad3	IDA		Rat	PMID:17545585\|RGD:2300403
Cellular Component	GO:0005829	cytosol	SMAD3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	SMAD3	IGI	UniProtKB:Q96AC1	Human	PMID:23723426
Cellular Component	GO:0071144	heteromeric SMAD protein complex	SMAD3	IPI		Human	PMID:15350224
Cellular Component	GO:0071144	heteromeric SMAD protein complex	SMAD3	IDA		Human	PMID:21828274
Cellular Component	GO:0005637	nuclear inner membrane	SMAD3	IDA		Human	PMID:15647271
Cellular Component	GO:0005654	nucleoplasm	SMAD3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SMAD3	IDA		Human	PMID:12446380
Cellular Component	GO:0005634	nucleus	SMAD3	IDA		Human	PMID:16007207
Cellular Component	GO:0005634	nucleus	SMAD3	IDA		Human	PMID:21145499
Cellular Component	GO:0005634	nucleus	SMAD3	IDA		Human	PMID:21947082
Cellular Component	GO:0005634	nucleus	SMAD3	IDA		Human	PMID:25893292
Cellular Component	GO:0005634	nucleus	SMAD3	IDA		Human	PMID:9311995
Cellular Component	GO:0005634	nucleus	SMAD3	IGI	UniProtKB:Q96AC1	Human	PMID:23723426
Cellular Component	GO:0005634	nucleus	Smad3	IDA		Mouse	MGI:MGI:5009194\|PMID:11160896
Cellular Component	GO:0005634	nucleus	Smad3	IDA		Mouse	MGI:MGI:4939579\|PMID:21145499
Cellular Component	GO:0005634	nucleus	Smad3	IDA		Mouse	PMID:12943993
Cellular Component	GO:0005634	nucleus	Smad3	IDA		Mouse	PMID:15282343
Cellular Component	GO:0005634	nucleus	Smad3	IDA		Rat	PMID:16959941\|RGD:1599906
Cellular Component	GO:0005634	nucleus	Smad3	IDA		Rat	PMID:17545585\|RGD:2300403
Cellular Component	GO:0005634	nucleus	Smad3	IDA		Rat	PMID:22073128\|RGD:8554355
Cellular Component	GO:0005634	nucleus	Smad3	IDA		Rat	PMID:16690606\|RGD:15023472
Cellular Component	GO:0005634	nucleus	Smad3	IDA		Rat	PMID:20097766\|RGD:11079190
Cellular Component	GO:0005886	plasma membrane	Smad3	IDA		Mouse	PMID:12543979
Cellular Component	GO:0032991	protein-containing complex	Smad3	IDA		Rat	PMID:16959941\|RGD:1599906
Cellular Component	GO:0043235	receptor complex	SMAD3	IMP		Human	PMID:8774881
Cellular Component	GO:0071141	SMAD protein complex	SMAD3	IDA		Human	PMID:18832382
Cellular Component	GO:0071141	SMAD protein complex	SMAD3	IDA		Human	PMID:21947082
Cellular Component	GO:0005667	transcription regulator complex	SMAD3	IPI		Human	PMID:25060702
Cellular Component	GO:0005667	transcription regulator complex	SMAD3	IDA		Human	PMID:21947082
Cellular Component	GO:0005667	transcription regulator complex	Smad3	IDA		Rat	PMID:16891311\|RGD:1625706
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	SMAD3	IMP		Human	PMID:15107418
Biological Process	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Smad3	IMP		Rat	PMID:11839804\|RGD:2301029
Biological Process	GO:0032924	activin receptor signaling pathway	SMAD3	IMP		Human	PMID:15150278
Biological Process	GO:0030325	adrenal gland development	Smad3	IDA		Rat	PMID:12844345\|RGD:728125
Biological Process	GO:0045216	cell-cell junction organization	SMAD3	IMP		Human	PMID:18505915
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	SMAD3	IDA		Human	PMID:12902338
Biological Process	GO:0098586	cellular response to virus	Smad3	IDA		Mouse	PMID:18802055
Biological Process	GO:0048589	developmental growth	Smad3	IGI	MGI:MGI:108051	Mouse	PMID:15183723
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	Smad3	IGI	MGI:MGI:108051	Mouse	PMID:15183723
Biological Process	GO:0048617	embryonic foregut morphogenesis	Smad3	IGI	MGI:MGI:108051	Mouse	PMID:15183723
Biological Process	GO:0009880	embryonic pattern specification	Smad3	IGI	MGI:MGI:108051	Mouse	PMID:15183723
Biological Process	GO:0007492	endoderm development	Smad3	IGI	MGI:MGI:108051	Mouse	PMID:15183723
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	SMAD3	IMP		Human	PMID:15334054
Biological Process	GO:0007369	gastrulation	Smad3	IGI	MGI:MGI:108051	Mouse	PMID:15183723
Biological Process	GO:0001947	heart looping	Smad3	IGI	MGI:MGI:108051	Mouse	PMID:15183723
Biological Process	GO:0006955	immune response	SMAD3	IMP		Human	PMID:16886151
Biological Process	GO:0002520	immune system development	Smad3	IGI	MGI:MGI:108051	Mouse	PMID:15183723
Biological Process	GO:0001701	in utero embryonic development	Smad3	IGI	MGI:MGI:108051	Mouse	PMID:15183723
Biological Process	GO:0007254	JNK cascade	Smad3	IMP		Mouse	PMID:18802055
Biological Process	GO:0070306	lens fiber cell differentiation	Smad3	IMP		Mouse	PMID:17215516
Biological Process	GO:0001889	liver development	Smad3	IGI	MGI:MGI:108051	Mouse	PMID:15183723
Biological Process	GO:0000165	MAPK cascade	Smad3	IMP		Mouse	PMID:18802055
Biological Process	GO:0007498	mesoderm development	smad3a	IMP	ZFIN:ZDB-MRPHLNO-050119-1	Zfish	ZFIN:ZDB-PUB-170709-3
Biological Process	GO:0007498	mesoderm development	smad3a	IGI	ZFIN:ZDB-GENE-990630-14	Zfish	PMID:28687631
Biological Process	GO:0001707	mesoderm formation	Smad3	IMP	MGI:MGI:1857696	Mouse	PMID:15084457
Biological Process	GO:0043066	negative regulation of apoptotic process	Smad3	IDA		Rat	PMID:14517210\|RGD:2300426
Biological Process	GO:1903243	negative regulation of cardiac muscle hypertrophy in response to stress	Smad3	IGI	RNAcentral:URS0000554A4F_10116	Rat	PMID:27038547\|RGD:11535100
Biological Process	GO:0030308	negative regulation of cell growth	SMAD3	IDA		Human	PMID:8774881
Biological Process	GO:0008285	negative regulation of cell population proliferation	SMAD3	IMP		Human	PMID:14555988
Biological Process	GO:0008285	negative regulation of cell population proliferation	Smad3	IDA		Rat	PMID:15987742\|RGD:2300418
Biological Process	GO:0051481	negative regulation of cytosolic calcium ion concentration	SMAD3	IDA		Human	PMID:27038547
Biological Process	GO:0045599	negative regulation of fat cell differentiation	SMAD3	IDA		Human	PMID:19816956
Biological Process	GO:0010629	negative regulation of gene expression	SMAD3	IMP		Human	PMID:24378993
Biological Process	GO:0050728	negative regulation of inflammatory response	Smad3	IMP		Mouse	MGI:MGI:1352043\|PMID:10559937
Biological Process	GO:0061767	negative regulation of lung blood pressure	Smad3	IGI	RNAcentral:URS0000554A4F_10116	Rat	PMID:27038547\|RGD:11535100
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	Smad3	IGI	MGI:MGI:1316736	Mouse	PMID:15150273
Biological Process	GO:0033689	negative regulation of osteoblast proliferation	Smad3	IMP		Mouse	MGI:MGI:5285145\|PMID:21035443
Biological Process	GO:0042177	negative regulation of protein catabolic process	Smad3	IDA		Rat	PMID:16690606\|RGD:15023472
Biological Process	GO:0042177	negative regulation of protein catabolic process	Smad3	IMP		Rat	PMID:20097766\|RGD:11079190
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	SMAD3	IMP		Human	PMID:14555988
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	SMAD3	IDA		Human	PMID:28467929
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	SMAD3	IDA		Human	PMID:8774881
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Smad3	IDA		Mouse	PMID:9702197
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Smad3	IDA		Mouse	PMID:11711431
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Smad3	IMP		Rat	PMID:16205635\|RGD:2300406
Biological Process	GO:0061045	negative regulation of wound healing	Smad3	IMP		Mouse	MGI:MGI:1352043\|PMID:10559937
Biological Process	GO:0061045	negative regulation of wound healing	Smad3	IMP		Mouse	MGI:MGI:5284806\|PMID:14617288
Biological Process	GO:0061045	negative regulation of wound healing	Smad3	IMP		Mouse	MGI:MGI:5285145\|PMID:21035443
Biological Process	GO:0038092	nodal signaling pathway	SMAD3	IMP		Human	PMID:15150278
Biological Process	GO:0002076	osteoblast development	Smad3	IGI	MGI:MGI:1316736	Mouse	PMID:15150273
Biological Process	GO:0001649	osteoblast differentiation	Smad3	IMP		Mouse	MGI:MGI:3654245\|PMID:11585338
Biological Process	GO:0048340	paraxial mesoderm morphogenesis	Smad3	IMP	MGI:MGI:1857696	Mouse	PMID:15084457
Biological Process	GO:0060039	pericardium development	Smad3	IGI	MGI:MGI:108051	Mouse	PMID:15183723
Biological Process	GO:0010694	positive regulation of alkaline phosphatase activity	Smad3	IDA		Rat	PMID:12096832\|RGD:727387
Biological Process	GO:0030501	positive regulation of bone mineralization	Smad3	IDA		Rat	PMID:12096832\|RGD:727387
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	Smad3	IMP		Rat	PMID:20097766\|RGD:11079190
Biological Process	GO:0030335	positive regulation of cell migration	Smad3	IMP		Rat	PMID:17545585\|RGD:2300403
Biological Process	GO:0032332	positive regulation of chondrocyte differentiation	Smad3	IMP		Mouse	MGI:MGI:5285145\|PMID:21035443
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	SMAD3	IDA		Human	PMID:9111321
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	SMAD3	IDA		Human	PMID:9311995
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	SMAD3	IDA		Human	PMID:9732876
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Smad3	IDA		Mouse	PMID:15282343
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Smad3	IDA		Mouse	PMID:15464984
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	SMAD3	IMP		Human	PMID:18505915
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	SMAD3	IDA		Human	PMID:21307346
Biological Process	GO:1901203	positive regulation of extracellular matrix assembly	SMAD3	IDA		Human	PMID:21307346
Biological Process	GO:0051894	positive regulation of focal adhesion assembly	Smad3	IDA		Rat	PMID:15987742\|RGD:2300418
Biological Process	GO:0010628	positive regulation of gene expression	SMAD3	IDA		Human	PMID:21307346
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	Smad3	IMP		Rat	PMID:16371439\|RGD:2300404
Biological Process	GO:1902895	positive regulation of miRNA transcription	SMAD3	IDA		Human	PMID:24378993
Biological Process	GO:1902895	positive regulation of miRNA transcription	SMAD3	IMP		Human	PMID:24378993
Biological Process	GO:1902895	positive regulation of miRNA transcription	SMAD3	IMP		Human	PMID:26311719
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	SMAD3	IDA		Human	PMID:27038547
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	Smad3	IGI	RNAcentral:URS0000554A4F_10116	Rat	PMID:27038547\|RGD:11535100
Biological Process	GO:0050927	positive regulation of positive chemotaxis	Smad3	IDA		Rat	PMID:15987742\|RGD:2300418
Biological Process	GO:0051496	positive regulation of stress fiber assembly	Smad3	IDA		Rat	PMID:15987742\|RGD:2300418
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	SMAD3	IMP		Human	PMID:14555988
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	SMAD3	IDA		Human	PMID:18832382
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	SMAD3	IDA		Human	PMID:8774881
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad3	IDA		Mouse	MGI:MGI:5688819\|PMID:25065622
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad3	IMP		Mouse	PMID:18802055
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad3	IGI	MGI:MGI:106658	Mouse	PMID:16824956
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad3	IGI	MGI:MGI:108051	Mouse	PMID:17159989
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad3	IDA		Mouse	PMID:16619037
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad3	IGI	MGI:MGI:894293	Mouse	PMID:17159989
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad3	IDA		Mouse	PMID:15150273
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad3	IGI	MGI:MGI:108051	Mouse	PMID:23390484
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad3	IGI	MGI:MGI:1314872	Mouse	PMID:17159989
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad3	IGI	MGI:MGI:98727	Mouse	PMID:17159989
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad3	IDA		Mouse	PMID:12943993
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad3	IGI	MGI:MGI:1344313	Mouse	PMID:16824956
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad3	IGI	MGI:MGI:1316736	Mouse	PMID:15150273
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad3	IDA		Rat	PMID:12702545\|RGD:1299323
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad3	IMP		Rat	PMID:16891311\|RGD:1625706
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad3	IMP		Rat	PMID:22073128\|RGD:8554355
Biological Process	GO:0032916	positive regulation of transforming growth factor beta3 production	Smad3	IMP		Rat	PMID:16891311\|RGD:1625706
Biological Process	GO:0060215	primitive hemopoiesis	smad3a	IMP	ZFIN:ZDB-MRPHLNO-050119-1	Zfish	ZFIN:ZDB-PUB-170709-3
Biological Process	GO:0060215	primitive hemopoiesis	smad3a	IGI	ZFIN:ZDB-GENE-990630-14	Zfish	PMID:28687631
Biological Process	GO:0050821	protein stabilization	Smad3	IMP		Rat	PMID:20097766\|RGD:11079190
Biological Process	GO:0051098	regulation of binding	Smad3	IDA		Mouse	PMID:15282343
Biological Process	GO:0006355	regulation of DNA-templated transcription	SMAD3	IDA		Human	PMID:25060702
Biological Process	GO:0006355	regulation of DNA-templated transcription	smad3a	IPI	ZFIN:ZDB-GENE-000616-6	Zfish	PMID:21159776
Biological Process	GO:0050678	regulation of epithelial cell proliferation	Smad3	IMP	MGI:MGI:1857695	Mouse	PMID:12845704
Biological Process	GO:0050776	regulation of immune response	Smad3	IMP		Mouse	MGI:MGI:1332876\|PMID:10064594
Biological Process	GO:0016202	regulation of striated muscle tissue development	Smad3	IDA		Mouse	PMID:11711431
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	SMAD3	IDA		Human	PMID:21947082
Biological Process	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	SMAD3	IMP		Human	PMID:8774881
Biological Process	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	Smad3	IDA		Mouse	PMID:11711431
Biological Process	GO:0032909	regulation of transforming growth factor beta2 production	SMAD3	IMP		Human	PMID:12411310
Biological Process	GO:0001666	response to hypoxia	SMAD3	IMP		Human	PMID:12411310
Biological Process	GO:0023019	signal transduction involved in regulation of gene expression	Smad3	IMP		Rat	PMID:22073128\|RGD:8554355
Biological Process	GO:0001501	skeletal system development	Smad3	IGI	MGI:MGI:108051	Mouse	PMID:15183723
Biological Process	GO:0007183	SMAD protein complex assembly	SMAD3	IDA		Human	PMID:10823886
Biological Process	GO:0007183	SMAD protein complex assembly	SMAD3	IDA		Human	PMID:9111321
Biological Process	GO:0007183	SMAD protein complex assembly	Smad3	IPI	RGD:3033\|RGD:2401	Rat	PMID:16959941\|RGD:1599906
Biological Process	GO:0060395	SMAD protein signal transduction	Smad3	IGI	MGI:MGI:108051	Mouse	PMID:23390484
Biological Process	GO:0001756	somitogenesis	Smad3	IMP	MGI:MGI:108051	Mouse	PMID:15183723
Biological Process	GO:0042110	T cell activation	Smad3	IMP		Mouse	MGI:MGI:1332876\|PMID:10064594
Biological Process	GO:0030878	thyroid gland development	Smad3	IGI	MGI:MGI:108051	Mouse	PMID:15183723
Biological Process	GO:0060290	transdifferentiation	Smad3	IDA		Rat	PMID:15987742\|RGD:2300418
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	SMAD3	IDA		Human	PMID:18548003
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	SMAD3	IDA		Human	PMID:21947082
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	SMAD3	IDA		Human	PMID:28467929
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	SMAD3	IDA		Human	PMID:9732876
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Smad3	IDA		Mouse	PMID:16619037
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Smad3	IMP		Mouse	PMID:15239668
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Smad3	IDA		Mouse	PMID:21937600
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Smad3	IDA		Mouse	PMID:15239668
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Smad3	IMP		Rat	PMID:16371439\|RGD:2300404
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Smad3	IMP		Rat	PMID:16891311\|RGD:1625706
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Smad3	IMP		Rat	PMID:22073128\|RGD:8554355
Biological Process	GO:0001657	ureteric bud development	Smad3	IEP		Mouse	MGI:MGI:3525982\|PMID:14656760

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.