About   Help   FAQ
Gene Ontology Browser
Term Detail
GO term:liver development
GO id:GO:0001889
Definition:The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
Number of paths to term: 13

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-aorgan development
                                        is-agland development
                                                is-aadrenal gland development +
                                                is-acement gland development
                                                is-acloacal gland development
                                                is-aexocrine pancreas development
                                                part-ofgland morphogenesis +
                                                is-ahatching gland development
                                                is-alacrimal gland development +
                                                is-aliver development [GO:0001889] (97 genes, 111 annotations)
                                                        part-ofdetermination of liver left/right asymmetry
                                                        part-ofhepatoblast differentiation
                                                        part-ofhepatocyte differentiation +
                                                        part-ofintrahepatic bile duct development
                                                        part-ofliver morphogenesis +
                                                        is-aliver regeneration
                                                        part-ofliver trabecula formation
                                                is-alymph gland development +
                                                is-amammary gland development +
                                                is-aneurohypophysis development +
                                                is-aparathyroid gland development +
                                                is-apineal gland development
                                                is-apituitary gland development +
                                                is-aprostate gland development +
                                                is-aring gland development
                                                is-asalivary gland development +
                                                is-asebaceous gland development +
                                                is-aseminal vesicle development +
                                                is-asweat gland development +
                                                is-athymus development +
                                                is-athyroid gland development +
                                                is-atrachea gland development
                                                is-auterine gland development


obsolete Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-asystem development
                                        is-ahepaticobiliary system development
                                                part-ofcommon bile duct development +
                                                part-ofcystic duct development
                                                part-ofgall bladder development
                                                part-ofhepatic duct development
                                                part-ofliver development [GO:0001889] (97 genes, 111 annotations)
                                                        part-ofdetermination of liver left/right asymmetry
                                                        part-ofhepatoblast differentiation
                                                        part-ofhepatocyte differentiation +
                                                        part-ofintrahepatic bile duct development
                                                        part-ofliver morphogenesis +
                                                        is-aliver regeneration
                                                        part-ofliver trabecula formation


obsolete Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-asystem development
                                        part-oforgan development
                                                is-agland development
                                                        is-aadrenal gland development +
                                                        is-acement gland development
                                                        is-acloacal gland development
                                                        is-aexocrine pancreas development
                                                        part-ofgland morphogenesis +
                                                        is-ahatching gland development
                                                        is-alacrimal gland development +
                                                        is-aliver development [GO:0001889] (97 genes, 111 annotations)
                                                                part-ofdetermination of liver left/right asymmetry
                                                                part-ofhepatoblast differentiation
                                                                part-ofhepatocyte differentiation +
                                                                part-ofintrahepatic bile duct development
                                                                part-ofliver morphogenesis +
                                                                is-aliver regeneration
                                                                part-ofliver trabecula formation
                                                        is-alymph gland development +
                                                        is-amammary gland development +
                                                        is-aneurohypophysis development +
                                                        is-aparathyroid gland development +
                                                        is-apineal gland development
                                                        is-apituitary gland development +
                                                        is-aprostate gland development +
                                                        is-aring gland development
                                                        is-asalivary gland development +
                                                        is-asebaceous gland development +
                                                        is-aseminal vesicle development +
                                                        is-asweat gland development +
                                                        is-athymus development +
                                                        is-athyroid gland development +
                                                        is-atrachea gland development
                                                        is-auterine gland development


obsolete Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-agland development
                                        is-aadrenal gland development +
                                        is-acement gland development
                                        is-acloacal gland development
                                        is-aexocrine pancreas development
                                        part-ofgland morphogenesis +
                                        is-ahatching gland development
                                        is-alacrimal gland development +
                                        is-aliver development [GO:0001889] (97 genes, 111 annotations)
                                                part-ofdetermination of liver left/right asymmetry
                                                part-ofhepatoblast differentiation
                                                part-ofhepatocyte differentiation +
                                                part-ofintrahepatic bile duct development
                                                part-ofliver morphogenesis +
                                                is-aliver regeneration
                                                part-ofliver trabecula formation
                                        is-alymph gland development +
                                        is-amammary gland development +
                                        is-aneurohypophysis development +
                                        is-aparathyroid gland development +
                                        is-apineal gland development
                                        is-apituitary gland development +
                                        is-aprostate gland development +
                                        is-aring gland development
                                        is-asalivary gland development +
                                        is-asebaceous gland development +
                                        is-aseminal vesicle development +
                                        is-asweat gland development +
                                        is-athymus development +
                                        is-athyroid gland development +
                                        is-atrachea gland development
                                        is-auterine gland development


obsolete Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-ahepaticobiliary system development
                                                        part-ofcommon bile duct development +
                                                        part-ofcystic duct development
                                                        part-ofgall bladder development
                                                        part-ofhepatic duct development
                                                        part-ofliver development [GO:0001889] (97 genes, 111 annotations)
                                                                part-ofdetermination of liver left/right asymmetry
                                                                part-ofhepatoblast differentiation
                                                                part-ofhepatocyte differentiation +
                                                                part-ofintrahepatic bile duct development
                                                                part-ofliver morphogenesis +
                                                                is-aliver regeneration
                                                                part-ofliver trabecula formation


obsolete Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-agland development
                                                                is-aadrenal gland development +
                                                                is-acement gland development
                                                                is-acloacal gland development
                                                                is-aexocrine pancreas development
                                                                part-ofgland morphogenesis +
                                                                is-ahatching gland development
                                                                is-alacrimal gland development +
                                                                is-aliver development [GO:0001889] (97 genes, 111 annotations)
                                                                        part-ofdetermination of liver left/right asymmetry
                                                                        part-ofhepatoblast differentiation
                                                                        part-ofhepatocyte differentiation +
                                                                        part-ofintrahepatic bile duct development
                                                                        part-ofliver morphogenesis +
                                                                        is-aliver regeneration
                                                                        part-ofliver trabecula formation
                                                                is-alymph gland development +
                                                                is-amammary gland development +
                                                                is-aneurohypophysis development +
                                                                is-aparathyroid gland development +
                                                                is-apineal gland development
                                                                is-apituitary gland development +
                                                                is-aprostate gland development +
                                                                is-aring gland development
                                                                is-asalivary gland development +
                                                                is-asebaceous gland development +
                                                                is-aseminal vesicle development +
                                                                is-asweat gland development +
                                                                is-athymus development +
                                                                is-athyroid gland development +
                                                                is-atrachea gland development
                                                                is-auterine gland development


obsolete Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-ahepaticobiliary system development
                                                        part-ofcommon bile duct development +
                                                        part-ofcystic duct development
                                                        part-ofgall bladder development
                                                        part-ofhepatic duct development
                                                        part-ofliver development [GO:0001889] (97 genes, 111 annotations)
                                                                part-ofdetermination of liver left/right asymmetry
                                                                part-ofhepatoblast differentiation
                                                                part-ofhepatocyte differentiation +
                                                                part-ofintrahepatic bile duct development
                                                                part-ofliver morphogenesis +
                                                                is-aliver regeneration
                                                                part-ofliver trabecula formation


obsolete Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-agland development
                                                                is-aadrenal gland development +
                                                                is-acement gland development
                                                                is-acloacal gland development
                                                                is-aexocrine pancreas development
                                                                part-ofgland morphogenesis +
                                                                is-ahatching gland development
                                                                is-alacrimal gland development +
                                                                is-aliver development [GO:0001889] (97 genes, 111 annotations)
                                                                        part-ofdetermination of liver left/right asymmetry
                                                                        part-ofhepatoblast differentiation
                                                                        part-ofhepatocyte differentiation +
                                                                        part-ofintrahepatic bile duct development
                                                                        part-ofliver morphogenesis +
                                                                        is-aliver regeneration
                                                                        part-ofliver trabecula formation
                                                                is-alymph gland development +
                                                                is-amammary gland development +
                                                                is-aneurohypophysis development +
                                                                is-aparathyroid gland development +
                                                                is-apineal gland development
                                                                is-apituitary gland development +
                                                                is-aprostate gland development +
                                                                is-aring gland development
                                                                is-asalivary gland development +
                                                                is-asebaceous gland development +
                                                                is-aseminal vesicle development +
                                                                is-asweat gland development +
                                                                is-athymus development +
                                                                is-athyroid gland development +
                                                                is-atrachea gland development
                                                                is-auterine gland development


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-ahepaticobiliary system development
                                                        part-ofcommon bile duct development +
                                                        part-ofcystic duct development
                                                        part-ofgall bladder development
                                                        part-ofhepatic duct development
                                                        part-ofliver development [GO:0001889] (97 genes, 111 annotations)
                                                                part-ofdetermination of liver left/right asymmetry
                                                                part-ofhepatoblast differentiation
                                                                part-ofhepatocyte differentiation +
                                                                part-ofintrahepatic bile duct development
                                                                part-ofliver morphogenesis +
                                                                is-aliver regeneration
                                                                part-ofliver trabecula formation


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-agland development
                                                                is-aadrenal gland development +
                                                                is-acement gland development
                                                                is-acloacal gland development
                                                                is-aexocrine pancreas development
                                                                part-ofgland morphogenesis +
                                                                is-ahatching gland development
                                                                is-alacrimal gland development +
                                                                is-aliver development [GO:0001889] (97 genes, 111 annotations)
                                                                        part-ofdetermination of liver left/right asymmetry
                                                                        part-ofhepatoblast differentiation
                                                                        part-ofhepatocyte differentiation +
                                                                        part-ofintrahepatic bile duct development
                                                                        part-ofliver morphogenesis +
                                                                        is-aliver regeneration
                                                                        part-ofliver trabecula formation
                                                                is-alymph gland development +
                                                                is-amammary gland development +
                                                                is-aneurohypophysis development +
                                                                is-aparathyroid gland development +
                                                                is-apineal gland development
                                                                is-apituitary gland development +
                                                                is-aprostate gland development +
                                                                is-aring gland development
                                                                is-asalivary gland development +
                                                                is-asebaceous gland development +
                                                                is-aseminal vesicle development +
                                                                is-asweat gland development +
                                                                is-athymus development +
                                                                is-athyroid gland development +
                                                                is-atrachea gland development
                                                                is-auterine gland development


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-agland development
                                        is-aadrenal gland development +
                                        is-acement gland development
                                        is-acloacal gland development
                                        is-aexocrine pancreas development
                                        part-ofgland morphogenesis +
                                        is-ahatching gland development
                                        is-alacrimal gland development +
                                        is-aliver development [GO:0001889] (97 genes, 111 annotations)
                                                part-ofdetermination of liver left/right asymmetry
                                                part-ofhepatoblast differentiation
                                                part-ofhepatocyte differentiation +
                                                part-ofintrahepatic bile duct development
                                                part-ofliver morphogenesis +
                                                is-aliver regeneration
                                                part-ofliver trabecula formation
                                        is-alymph gland development +
                                        is-amammary gland development +
                                        is-aneurohypophysis development +
                                        is-aparathyroid gland development +
                                        is-apineal gland development
                                        is-apituitary gland development +
                                        is-aprostate gland development +
                                        is-aring gland development
                                        is-asalivary gland development +
                                        is-asebaceous gland development +
                                        is-aseminal vesicle development +
                                        is-asweat gland development +
                                        is-athymus development +
                                        is-athyroid gland development +
                                        is-atrachea gland development
                                        is-auterine gland development


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-ahepaticobiliary system development
                                                        part-ofcommon bile duct development +
                                                        part-ofcystic duct development
                                                        part-ofgall bladder development
                                                        part-ofhepatic duct development
                                                        part-ofliver development [GO:0001889] (97 genes, 111 annotations)
                                                                part-ofdetermination of liver left/right asymmetry
                                                                part-ofhepatoblast differentiation
                                                                part-ofhepatocyte differentiation +
                                                                part-ofintrahepatic bile duct development
                                                                part-ofliver morphogenesis +
                                                                is-aliver regeneration
                                                                part-ofliver trabecula formation


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-agland development
                                                                is-aadrenal gland development +
                                                                is-acement gland development
                                                                is-acloacal gland development
                                                                is-aexocrine pancreas development
                                                                part-ofgland morphogenesis +
                                                                is-ahatching gland development
                                                                is-alacrimal gland development +
                                                                is-aliver development [GO:0001889] (97 genes, 111 annotations)
                                                                        part-ofdetermination of liver left/right asymmetry
                                                                        part-ofhepatoblast differentiation
                                                                        part-ofhepatocyte differentiation +
                                                                        part-ofintrahepatic bile duct development
                                                                        part-ofliver morphogenesis +
                                                                        is-aliver regeneration
                                                                        part-ofliver trabecula formation
                                                                is-alymph gland development +
                                                                is-amammary gland development +
                                                                is-aneurohypophysis development +
                                                                is-aparathyroid gland development +
                                                                is-apineal gland development
                                                                is-apituitary gland development +
                                                                is-aprostate gland development +
                                                                is-aring gland development
                                                                is-asalivary gland development +
                                                                is-asebaceous gland development +
                                                                is-aseminal vesicle development +
                                                                is-asweat gland development +
                                                                is-athymus development +
                                                                is-athyroid gland development +
                                                                is-atrachea gland development
                                                                is-auterine gland development


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/21/2015
MGI 5.22
The Jackson Laboratory