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Gene Ontology Browser
Term Detail
GO term:transcription factor activity, sequence-specific DNA binding
Synonym: sequence-specific DNA binding transcription factor activity
Synonym: transcription factor activity
GO id:GO:0003700
Alternate id: GO:0000130
Definition:Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-amolecular_function
                is-anucleic acid binding transcription factor activity
                        is-aRNA binding transcription factor activity +
                        is-atranscription factor activity, sequence-specific DNA binding [GO:0003700] (1034 genes, 1972 annotations)
                                is-abacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding +
                                is-amitochondrial RNA polymerase transcription factor activity, sequence-specific DNA binding +
                                is-aRNA polymerase I transcription factor activity, sequence-specific DNA binding +
                                is-aRNA polymerase II transcription factor activity, sequence-specific DNA binding +
                                is-aRNA polymerase III transcription factor activity, sequence-specific DNA binding +
                                is-atranscription antitermination factor activity, DNA binding
                                is-atranscription factor activity, direct ligand regulated sequence-specific DNA binding +
                                is-atranscription factor activity, metal ion regulated sequence-specific DNA binding +
                                is-atranscription factor activity, sequence-specific DNA binding transcription factor recruiting +
                                is-atranscription factor activity, sequence-specific DNA binding, RNA polymerase recruiting


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory