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All mouse models of ovarian disease with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | ovarian cancer |
\Amhr2tm3(cre)Bhr/\Amhr2+ \Ctnnb1tm1Mmt/\Ctnnb1+ |
involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 | J:186144 | View | |||
| ovarian cancer |
\Amhr2tm3(cre)Bhr/\Amhr2+ \Ctnnb1tm1Mmt/\Ctnnb1+ \Ptentm1Hwu/\Ptentm1Hwu |
involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 | J:186144 | View | ||||
| ovarian cancer |
\Ctnnb1tm1Mmt/\Ctnnb1+ \Krastm4Tyj/\Kras+ \Amhr2tm3(cre)Bhr/\Amhr2+ |
involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 | J:186144 | View | ||||
| ovarian cancer |
\Ctnnb1tm1Mmt/\Ctnnb1+ \Krastm4Tyj/\Kras+ \Tg(CYP19A1-cre)1Jri/0 |
involves: 129S4/SvJae * 129X1/SvJ * C57BL/6 | J:186144 | View | ||||
| ovarian cancer |
\Ctnnb1tm1Mmt/\Ctnnb1+ \Ptentm1Hwu/\Ptentm1Hwu \Tg(CYP19A1-cre)1Jri/0 |
involves: 129S4/SvJae * 129X1/SvJ * C57BL/6 | J:186144 | View | ||||
| ovarian cancer |
\Ctnnb1tm1Mmt/\Ctnnb1+ \Tg(CYP19A1-cre)1Jri/0 |
involves: 129X1/SvJ * C57BL/6 | J:186144 | View | ||||
| primary ovarian insufficiency 12 | \Syce1em1Rrca/\Syce1em1Rrca | involves: C57BL/6J | J:309952 | View | ||||
| primary ovarian insufficiency 13 | \Msh5em1Jzc/\Msh5em1Jzc | involves: C57BL/6 | J:241778 | View | ||||
| primary ovarian insufficiency 16 | \Bnc1tm1.1Nju/\Bnc1+ | involves: C57BL/6NTac | J:266539 | View | ||||
| primary ovarian insufficiency 16 | \Bnc1tm1.1Nju/\Bnc1tm1.1Nju | involves: C57BL/6NTac | J:266539 | View | ||||
| primary ovarian insufficiency 19 | \Hsf2bpem2Amp/\Hsf2bpem2Amp | involves: C57BL/6J * CBA/J | J:303558 | View | ||||
| | dermoid cyst of ovary |
\Foxo3mommeR1/\Foxo3mommeR1 \Tg(HBA1-GFP)1Ew/\Tg(HBA1-GFP)1Ew |
FVB/NJ-Foxo3mommeR1 Tg(HBA1-Gfp)1Ew | J:170710 | View | |||
| ovarian cancer |
\Apctm1Rsmi/\Apctm1Rsmi \Pgrtm2(cre)Lyd/\Pgr+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J | J:210095 | View | ||||
| ovarian cancer |
\Apctm1Tno/\Apctm1Tno \Ptentm2Mak/\Ptentm2Mak |
involves: 129P2/OlaHsd * 129S4/SvJae | J:120955 | View | ||||
| ovarian disease | \Patl2tm1b(EUCOMM)Hmgu/\Patl2tm1b(EUCOMM)Hmgu | involves: C57BL/6N * FVB/N | J:264835 | View | ||||
| ovarian hyperstimulation syndrome | \Nr1h3tm1Djm/\Nr1h3tm1Djm | involves: 129S6/SvEvTac * C57BL/6 | J:158168 | View | ||||
| polycystic ovary syndrome | \Akt2tm1Hem/\Akt2tm1Hem | involves: 129P2/OlaHsd | J:185012 | View | ||||
| primary ovarian insufficiency | \Fancftm1Nki/\Fancftm1Nki | involves: 129P2/OlaHsd * FVB | J:180025 | View | ||||
| primary ovarian insufficiency | \Polr3hem2Cfe/\Polr3hem2Cfe | involves: C57BL/6J * SJL/J | J:290735 | View | ||||
| primary ovarian insufficiency | \Rnf111em1Fzh/\Rnf111+ | C57BL/6J-Rnf111em1Fzh | J:361059 | View | ||||
| primary ovarian insufficiency | \Rnf111em2Fzh/\Rnf111+ | C57BL/6J-Rnf111em2Fzh | J:361059 | View | ||||
| | ovarian cancer |
\Arid1atm1.1Mag/\Arid1atm1.1Mag \Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/\Gt(ROSA)26Sor+ |
involves: 129S6/SvEvTac * CD-1 | J:219794 | View | |||
| ovarian cancer |
\Brca1tm1Brn/\Brca1tm1Brn \Tg(Krt18-EGFP,-TAg121)36Ysng/0 \Trp53tm1Brn/\Trp53tm1Brn |
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N | J:189304 | View | ||||
| ovarian cancer |
\Brca1tm1Brn/\Brca1tm1Brn \Tg(Krt18-EGFP,-TAg121)36Ysng/0 \Trp53tm1Brn/\Trp53tm2Tyj |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N | J:189304 | View | ||||
| ovarian cancer |
\Brca2tm1Brn/\Brca2tm1Brn \Tg(Krt18-EGFP,-TAg121)36Ysng/0 \Trp53tm1Brn/\Trp53tm2Tyj |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N | J:189304 | View | ||||
| ovarian cancer |
\Dicer1tm1Tara/\Dicer1tm1Tara \Ptentm1Hwu/\Ptentm1Hwu \Amhr2tm3(cre)Bhr/\Amhr2+ |
involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd | J:182161 | View | ||||
| ovarian cancer |
\Dicer1tm1Tara/\Dicer1tm1Tara \Ptentm1Hwu/\Ptentm1Hwu \Trp53tm2Tyj/\Trp53+ \Amhr2tm3(cre)Bhr/\Amhr2+ |
involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd | J:222579 | View | ||||
| ovarian cancer |
\Krastm4Tyj/\Kras+ \Ptentm1Hwu/\Ptentm1Hwu |
involves: 129S4/SvJae | J:161953 | View | ||||
| ovarian cancer |
\Krastm4Tyj/\Kras+ \Ptentm1Hwu/\Ptentm1Hwu |
involves: 129S4/SvJae * C57BL/6J | J:96296 | View | ||||
| ovarian cancer |
\Ptentm1Hwu/\Ptentm1Hwu \Trp53tm2Tyj/\Trp53+ \Amhr2tm3(cre)Bhr/\Amhr2+ |
involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd | J:222579 | View | ||||
| Transgenes and Other Mutations | dermoid cyst of ovary | \Tg(Amh-SMAD2*)#Jebu/0 | FVB/N-Tg(Amh-SMAD2*)#Jebu | J:200783 | View | |||
| ovarian cancer | \Tg(Amhr2-SV40TAg)1Dcco/0 | (C57BL/6 x C3H)F1 | J:82550 | View | ||||
| ovarian cancer | \Tg(CAG-lacZ,-SV40)#Bcv/0 | involves: FVB/N | J:158388 | View | ||||
| polycystic ovary syndrome | \Tg(Cyp17a1-NGF)2456Oje/\Tg(Cyp17a1-NGF)2456Oje | involves: C57BL/6J * DBA/2J | J:218686 | View | ||||
| Additional Complex Models | ovarian cancer |
\Amhr2tm3(cre)Bhr/\Amhr2+ \Smad1tm2Rob/\Smad1tm2.1Rob \Smad5tm1Huy/\Smad5tm1Huy |
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J | J:157310 | View | |||
| ovarian cancer |
\Amhr2tm3(cre)Bhr/\Amhr2+ \Smad1tm2Rob/\Smad1tm2Rob \Smad5tm1Huy/\Smad5tm1Huy |
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J | J:157310 | View | ||||
| ovarian cancer |
\Amhr2tm3(cre)Bhr/\Amhr2+ \Smad1tm2Rob/\Smad1tm2Rob \Smad5tm1Huy/\Smad5tm1Zuk |
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J | J:157310 | View | ||||
| ovarian cancer |
\Cdkn1btm1Ako/\Cdkn1b+ \KitW-v/\KitW-v |
involves: 129S1/Sv * C57BL/6J | J:236161 | View | ||||
| ovarian cancer |
\Cdkn1btm1Ako/\Cdkn1btm1Ako \KitW-v/\KitW-v |
involves: 129S1/Sv * C57BL/6J | J:236161 | View | ||||
| ovarian cancer |
\Foxo1tm1Rdp/\Foxo1tm1.1Rdp \Foxo3tm1Rdp/\Foxo3tm1.1Rdp \Amhr2tm3(cre)Bhr/\Amhr2+ |
involves: 129S6/SvEvTac * 129S7/SvEvBrd | J:232961 | View | ||||
| ovarian cancer |
\Foxo1tm1Rdp/\Foxo1tm1.1Rdp \Foxo3tm1Rdp/\Foxo3tm1.1Rdp \Tg(CYP19A1-cre)1Jri/0 |
involves: 129S6/SvEvTac | J:232961 | View | ||||
| ovarian cancer |
\KitW-v/\KitW-v \Trp53tm1Brn/\Trp53tm1Brn |
involves: 129P2/OlaHsd * C57BL/6J * FVB/N | J:236161 | View | ||||
| ovarian cancer |
\Rb1tm2Brn/\Rb1tm2Brn \Trp53tm1Brn/\Trp53tm1Brn |
involves: 129P2/OlaHsd | J:84345 | View | ||||
| ovarian cancer |
\Tg(Krt18-EGFP,-TAg121)36Ysng/0 \Trp53tm1Brn/\Trp53tm1Brn |
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N | J:189304 | View | ||||
| ovarian cancer |
\Tg(Krt18-EGFP,-TAg121)36Ysng/0 \Trp53tm1Brn/\Trp53tm2Tyj |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N | J:189304 | View | ||||
| polycystic ovary syndrome |
\Insrtm1Khn/\Insrtm1Khn \Leprtm1.1Chua/\Leprtm1.1Chua \Tg(Pomc1-cre)16Lowl/0 |
involves: 129 * 129S4/SvJae * 129S6/SvEvTac * C57BL/6J * FVB/N | J:192274 | View | ||||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | ovarian cancer | \Tg(Amhr2-Pik3ca*,-GFP)#Lzh/0 | involves: C3H * C57BL/6 | J:144834 | View | |||
| primary ovarian insufficiency | \Helqem1Eljt/\Helqem1Eljt | C57BL/6J-Helqem1Eljt | J:347863 | View | ||||