Tg(Gata4-RFP)2Vigr
Transgene Detail

Summary

• Symbol: Tg(Gata4-RFP)2Vigr
• Name: transgene insertion 2, Robert S Viger
• MGI ID: MGI:8213165
• Synonyms: Gata4p[5kb]-RFP
• Transgene: Tg(Gata4-RFP)2Vigr Location: unknown
• Alliance: Tg(Gata4-RFP)2Vigr page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The transgene insert comprises the rat Gata4 promoter (5 kb fragment containing exon 1 and upstream sequence) upstream of the red fluorescent protein cDNA. The transgene was co-injected, and co-integrated, with the Tg(Tyr)GwNpln transgene; five copies of the latter transgene integrated with two copies of the RFP transgene, replacing an 82 bp sequence (GRCm39:chr2:98497330-98497411) in predicted gene Gm10800. The transgene is expressed in testicular Sertoli cells and astrocytes and GNRH1-expressing neurons in the hypothalamus. (J:132976)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:132976 Pilon N, et al., Novel pre- and post-gastrulation expression of Gata4 within cells of the inner cell mass and migratory neural crest cells. Dev Dyn. 2008 Apr;237(4):1133-43
• All: 2 reference(s)