Tg(CYP19A1-cre)1Jri
Transgene Detail

Summary

• Symbol: Tg(CYP19A1-cre)1Jri
• Name: transgene insertion 1, JoAnne Richards
• MGI ID: MGI:3799733
• Synonyms: Cyp19-Cre, Tg(CYP19-cre)1Jri
• Transgene: Tg(CYP19A1-cre)1Jri Location: unknown
• Alliance: Tg(CYP19A1-cre)1Jri page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(CYP19A1-cre)1Jri expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  CYP19A1 (1588)

  Cyp19a1

  (MGI:88587)

• Mutation details: The transgene consisting of the 304 bp human CYP19 promoter was ligated to iCre cDNA. This promoter directs expression specifically in granulosa cells. (J:137019)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	CYP19A1 (human) Summary of all recombinase alleles driven by CYP19A1. Comparative matrix view of recombinase activities Alliance human CYP19A1 gene page

Disease models

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(CYP19A1-cre)1Jri

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:137019 Fan HY, et al., Selective expression of KrasG12D in granulosa cells of the mouse ovary causes defects in follicle development and ovulation. Development. 2008 Jun;135(12):2127-37
• All: 46 reference(s)