Fancf^tm1Nki
Targeted Allele Detail

Summary

• Symbol: Fancf^tm1Nki
• Name: Fanconi anemia, complementation group F; targeted mutation 1, The Netherlands Cancer Institute
• MGI ID: MGI:4398963
• Gene: Fancf Location: Chr7:51510325-51512015 bp, - strand Genetic Position: Chr7, 32.87 cM
• Alliance: Fancf^tm1Nki page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:180025
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed neo cassette was inserted in the genomic region deleting 165 nucleotides of the promoter region and 171 nucleotides of the open reading frame including the start site. (J:180025)

Disease models

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fancf Mutation: 8 strains or lines available

References

• Original: J:180025 Bakker ST, et al., Fancf-deficient mice are prone to develop ovarian tumours. J Pathol. 2012 Jan;226(1):28-39
• All: 1 reference(s)