| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | arteriovenous malformations of the brain | ENG* | Eng* | 1 model | Alliance of Genome Resources | ||
| arteriovenous malformations of the brain | KRAS* | Kras* | 2 models | Alliance of Genome Resources | |||
| cerebral cavernous malformation | KRIT1* | Krit1* | 1 model | Alliance of Genome Resources | |||
| cerebral cavernous malformation 2 | CCM2* | Ccm2* | 4 models | Alliance of Genome Resources | |||
| cerebral cavernous malformation 3 | PDCD10* | Pdcd10* | 2 models | Alliance of Genome Resources | |||
| | arteriovenous malformations of the brain | ACVRL1 | Acvrl1* | 1 model | Alliance of Genome Resources | ||
| arteriovenous malformations of the brain | NOTCH4 | Notch4* | 1 model | Alliance of Genome Resources | |||
| | arteriovenous malformations of the brain | IL6* | Il6 | Alliance of Genome Resources | |||
| brain infarction | ADM* | Adm | Alliance of Genome Resources | ||||
| brain infarction | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
| brain infarction | CYP2R1* | Cyp2r1 | Alliance of Genome Resources | ||||
| brain infarction | CFH* | Cfh, Cfhr4 | Alliance of Genome Resources | ||||
| brain infarction | ALOX5AP* | Alox5ap | Alliance of Genome Resources | ||||
| brain infarction | ALDH2* | Aldh2 | Alliance of Genome Resources | ||||
| brain ischemia | IGF1* | Igf1 | Alliance of Genome Resources | ||||
| brain ischemia | HSPA1B* | Hspa1b | Alliance of Genome Resources | ||||
| brain ischemia | FGF1* | Fgf1 | Alliance of Genome Resources | ||||
| brain ischemia | ANXA1* | Anxa1 | Alliance of Genome Resources | ||||
| brain ischemia | ANGPT1* | Angpt1 | Alliance of Genome Resources | ||||
| brain ischemia | CSF3* | Csf3 | Alliance of Genome Resources | ||||
| brain ischemia | MDK* | Mdk | Alliance of Genome Resources | ||||
| brain ischemia | PGF* | Pgf | Alliance of Genome Resources | ||||
| brain ischemia | PROZ* | Proz | Alliance of Genome Resources | ||||
| brain ischemia | SELE* | Sele | Alliance of Genome Resources | ||||
| carotid artery disease | AGT* | Agt | Alliance of Genome Resources | ||||
| carotid artery disease | PTGDS* | Ptgds | Alliance of Genome Resources | ||||
| carotid artery disease | PRL* | Prl | Alliance of Genome Resources | ||||
| carotid artery disease | PPARG* | Pparg | Alliance of Genome Resources | ||||
| carotid artery disease | MMP9* | Mmp9 | Alliance of Genome Resources | ||||
| carotid artery disease | MMP8* | Mmp8 | Alliance of Genome Resources | ||||
| carotid artery disease | MMP2* | Mmp2 | Alliance of Genome Resources | ||||
| carotid artery disease | MMP1* | Mmp1a, Mmp1b | Alliance of Genome Resources | ||||
| carotid artery disease | LUM* | Lum | Alliance of Genome Resources | ||||
| carotid artery disease | LTA* | Lta | Alliance of Genome Resources | ||||
| carotid artery disease | GSTP1* | Gstp1, Gstp2, Gstp3 | Alliance of Genome Resources | ||||
| carotid artery disease | GNB3* | Gnb3 | Alliance of Genome Resources | ||||
| carotid artery disease | FGB* | Fgb | Alliance of Genome Resources | ||||
| carotid artery disease | CETP* | ||||||
| carotid artery disease | CD14* | Cd14 | Alliance of Genome Resources | ||||
| carotid artery disease | AGTR1* | Agtr1a, Agtr1b | Alliance of Genome Resources | ||||
| carotid artery disease | XDH* | Xdh | Alliance of Genome Resources | ||||
| carotid artery disease | UCP2* | Ucp2 | Alliance of Genome Resources | ||||
| carotid artery disease | TLR4* | Tlr4 | Alliance of Genome Resources | ||||
| carotid artery disease | SREBF2* | Srebf2 | Alliance of Genome Resources | ||||
| carotid artery disease | SOD2* | Sod2 | Alliance of Genome Resources | ||||
| carotid artery disease | SELPLG* | Selplg | Alliance of Genome Resources | ||||
| carotid artery thrombosis | THBD* | Thbd | Alliance of Genome Resources | ||||
| carotid stenosis | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| carotid stenosis | PTGIS* | Ptgis | Alliance of Genome Resources | ||||
| carotid stenosis | MMP3* | Mmp3 | Alliance of Genome Resources | ||||
| carotid stenosis | MMP1* | Mmp1a, Mmp1b | Alliance of Genome Resources | ||||
| carotid stenosis | FABP2* | Fabp2 | Alliance of Genome Resources | ||||
| carotid stenosis | F2* | F2 | Alliance of Genome Resources | ||||
| carotid stenosis | MT2A*, MT1A, MT1B, MT1E, MT1F, MT1G, MT1H, MT1L, MT1M, MT1X | Mt1, Mt2 | Alliance of Genome Resources | ||||
| cerebral cavernous malformation | PON1* | Pon1 | Alliance of Genome Resources | ||||
| cerebral cavernous malformation | PIK3CA* | Pik3ca | Alliance of Genome Resources | ||||
| cerebral cavernous malformation 1 | KRIT1* | Krit1 | Alliance of Genome Resources | ||||
| cerebral cavernous malformation 1 | PTGIS* | Ptgis | Alliance of Genome Resources | ||||
| cerebral infarction | TBXAS1* | Tbxas1 | Alliance of Genome Resources | ||||
| cerebral infarction | ACE* | Ace | Alliance of Genome Resources | ||||
| cerebral infarction | AGXT2* | Agxt2 | Alliance of Genome Resources | ||||
| cerebral infarction | ALOX5AP* | Alox5ap | Alliance of Genome Resources | ||||
| cerebral infarction | APOA5* | Apoa5 | Alliance of Genome Resources | ||||
| cerebral infarction | APOE* | Apoe | Alliance of Genome Resources | ||||
| cerebral infarction | BHMT* | Bhmt | Alliance of Genome Resources | ||||
| cerebral infarction | CBS* | Cbs | Alliance of Genome Resources | ||||
| cerebral infarction | F2* | F2 | Alliance of Genome Resources | ||||
| cerebral infarction | F5* | F5 | Alliance of Genome Resources | ||||
| cerebral infarction | F7* | F7 | Alliance of Genome Resources | ||||
| cerebral infarction | FOLH1*, FOLH1B | Folh1 | Alliance of Genome Resources | ||||
| cerebral infarction | GCH1* | Gch1 | Alliance of Genome Resources | ||||
| cerebral infarction | GPX3* | Gpx3 | Alliance of Genome Resources | ||||
| cerebral infarction | GRIN1* | Grin1 | Alliance of Genome Resources | ||||
| cerebral infarction | HLA-A*, HLA-B*, HLA-C, HLA-E, HLA-F, HLA-G, HLA-H | H2-D1, H2-K1, H2-L, H2-M2, H2-M3, H2-M10.1, H2-M10.2, H2-M10.4, H2-Q1, H2-Q2, H2-Q4, H2-Q6, H2-Q7, H2-Q8, H2-Q10, H2-T23 | Alliance of Genome Resources | ||||
| cerebral infarction | HLA-DRB1*, HLA-DRB3, HLA-DRB4, HLA-DRB5 | H2-Eb1, H2-Eb2 | Alliance of Genome Resources | ||||
| cerebral infarction | H19* | H19 | Alliance of Genome Resources | ||||
| cerebral infarction | HNF1A* | Hnf1a | Alliance of Genome Resources | ||||
| cerebral infarction | IFNB1* | Ifnb1 | Alliance of Genome Resources | ||||
| cerebral infarction | ITGA9* | Itga9 | Alliance of Genome Resources | ||||
| cerebral infarction | KALRN* | Kalrn | Alliance of Genome Resources | ||||
| cerebral infarction | KCNN4* | Kcnn4 | Alliance of Genome Resources | ||||
| cerebral infarction | LIPG* | Lipg | Alliance of Genome Resources | ||||
| cerebral infarction | LTA* | Lta | Alliance of Genome Resources | ||||
| cerebral infarction | LTC4S* | Ltc4s | Alliance of Genome Resources | ||||
| cerebral infarction | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| cerebral infarction | MTR* | Mtr | Alliance of Genome Resources | ||||
| cerebral infarction | MYRF* | Myrf | Alliance of Genome Resources | ||||
| cerebral infarction | NR1H3* | Nr1h3 | Alliance of Genome Resources | ||||
| cerebral infarction | NTRK2* | Ntrk2 | Alliance of Genome Resources | ||||
| cerebral infarction | PARK7* | Park7 | Alliance of Genome Resources | ||||
| cerebral infarction | PDX1* | Pdx1 | Alliance of Genome Resources | ||||
| cerebral infarction | PHACTR1* | Phactr1 | Alliance of Genome Resources | ||||
| cerebral infarction | PON1* | Pon1 | Alliance of Genome Resources | ||||
| cerebral infarction | PON2* | Pon2 | Alliance of Genome Resources | ||||
| cerebral infarction | PROS1* | Pros1 | Alliance of Genome Resources | ||||
| cerebral infarction | PTGIS* | Ptgis | Alliance of Genome Resources | ||||
| cerebral infarction | SERPING1* | Serping1 | Alliance of Genome Resources | ||||
| cerebral infarction | THBD* | Thbd | Alliance of Genome Resources | ||||
| cerebral infarction | TNF* | Tnf | Alliance of Genome Resources | ||||
| cerebral infarction | TOMM40* | Tomm40 | Alliance of Genome Resources | ||||
| cerebral infarction | TYMS* | Tyms | Alliance of Genome Resources | ||||
| cerebrovascular disease | SELE* | Sele | Alliance of Genome Resources | ||||
| cerebrovascular disease | AGT* | Agt | Alliance of Genome Resources | ||||
| cerebrovascular disease | AGTR1* | Agtr1a, Agtr1b | Alliance of Genome Resources | ||||
| cerebrovascular disease | APOE* | Apoe | Alliance of Genome Resources | ||||
| cerebrovascular disease | G6PD* | G6pd2, G6pdx | Alliance of Genome Resources | ||||
| cerebrovascular disease | GLCE* | Glce | Alliance of Genome Resources | ||||
| cerebrovascular disease | LMNA* | Lmna | Alliance of Genome Resources | ||||
| cerebrovascular disease | NR1H3* | Nr1h3 | Alliance of Genome Resources | ||||
| cerebrovascular disease | P2RY12* | P2ry12 | Alliance of Genome Resources | ||||
| intracranial aneurysm | PKD1* | Pkd1 | Alliance of Genome Resources | ||||
| intracranial aneurysm | SOX17* | Sox17 | Alliance of Genome Resources | ||||
| intracranial aneurysm | VCAN* | Vcan | Alliance of Genome Resources | ||||
| intracranial aneurysm | MMP2* | Mmp2 | Alliance of Genome Resources | ||||
| intracranial aneurysm | ENG* | Eng | Alliance of Genome Resources | ||||
| intracranial aneurysm | COL22A1* | Col22a1 | Alliance of Genome Resources | ||||
| intracranial aneurysm | COL1A2* | Col1a2 | Alliance of Genome Resources | ||||
| intracranial aneurysm | BCL2* | Bcl2 | Alliance of Genome Resources | ||||
| intracranial aneurysm | KMT2D* | Kmt2d | Alliance of Genome Resources | ||||
| intracranial aneurysm | IL6* | Il6 | Alliance of Genome Resources | ||||
| intracranial aneurysm | MMP9* | Mmp9 | Alliance of Genome Resources | ||||
| intracranial aneurysm | PKD2* | Pkd2 | Alliance of Genome Resources | ||||
| intracranial berry aneurysm 12 | THSD1* | Thsd1 | Alliance of Genome Resources | ||||
| intracranial embolism | KL* | Kl | Alliance of Genome Resources | ||||
| intracranial vasospasm | HMOX1* | Hmox1 | Alliance of Genome Resources | ||||
| intracranial vasospasm | RYR1* | Ryr1 | Alliance of Genome Resources | ||||
| middle cerebral artery infarction | CSF3* | Csf3 | Alliance of Genome Resources | ||||
| middle cerebral artery infarction | SHH* | Shh | Alliance of Genome Resources | ||||
| middle cerebral artery infarction | PARK7* | Park7 | Alliance of Genome Resources | ||||
| middle cerebral artery infarction | NRG1* | Nrg1 | Alliance of Genome Resources | ||||
| middle cerebral artery infarction | NCAM1* | Ncam1 | Alliance of Genome Resources | ||||
| middle cerebral artery infarction | IL1RN* | Il1rn | Alliance of Genome Resources | ||||
| middle cerebral artery infarction | HMOX1* | Hmox1 | Alliance of Genome Resources | ||||
| middle cerebral artery infarction | F12* | F12 | Alliance of Genome Resources | ||||
| middle cerebral artery infarction | EPO* | Epo | Alliance of Genome Resources | ||||
| middle cerebral artery infarction | CXCL10* | Cxcl10 | Alliance of Genome Resources | ||||
| middle cerebral artery infarction | CRP* | Crp | Alliance of Genome Resources | ||||
| middle cerebral artery infarction | ALB* | Alb | Alliance of Genome Resources | ||||
| Moyamoya disease | GUCY1A1* | Gucy1a1 | Alliance of Genome Resources | ||||
| Moyamoya disease | ANO1* | Ano1 | Alliance of Genome Resources | ||||
| Moyamoya disease | ACTA2* | Acta2 | Alliance of Genome Resources | ||||
| Moyamoya disease | HLA-A*, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HLA-H | H2-D1, H2-K1, H2-L, H2-M2, H2-M3, H2-M10.1, H2-M10.2, H2-M10.4, H2-Q1, H2-Q2, H2-Q4, H2-Q6, H2-Q7, H2-Q8, H2-Q10, H2-T23 | Alliance of Genome Resources | ||||
| Moyamoya disease | PHACTR1* | Phactr1 | Alliance of Genome Resources | ||||
| Moyamoya disease | RNF213* | Rnf213 | 1 "NOT" model | Alliance of Genome Resources | |||
| Moyamoya disease | TIMP2* | Timp2 | Alliance of Genome Resources | ||||
| stroke | C1orf167* | ||||||
| stroke | CCL2*, CCL7, CCL8, CCL11, CCL13 | Ccl2, Ccl7, Ccl8, Ccl11, Ccl12 | Alliance of Genome Resources | ||||
| stroke | COL4A1* | Col4a1 | Alliance of Genome Resources | ||||
| stroke | CSF3* | Csf3 | Alliance of Genome Resources | ||||
| stroke | CYP11B2*, CYP11B1 | Cyp11b1, Cyp11b2 | Alliance of Genome Resources | ||||
| stroke | ENPP1* | Enpp1 | Alliance of Genome Resources | ||||
| stroke | EPHX2* | Ephx2 | Alliance of Genome Resources | ||||
| stroke | F2* | F2 | Alliance of Genome Resources | ||||
| stroke | F12* | F12 | Alliance of Genome Resources | ||||
| stroke | F13A1* | F13a1 | Alliance of Genome Resources | ||||
| stroke | FABP2* | Fabp2 | Alliance of Genome Resources | ||||
| stroke | HLA-DRB1*, HLA-DRB3, HLA-DRB4, HLA-DRB5 | H2-Eb1, H2-Eb2 | Alliance of Genome Resources | ||||
| stroke | FGB* | Fgb | Alliance of Genome Resources | ||||
| stroke | FGG* | Fgg | Alliance of Genome Resources | ||||
| stroke | GAS6* | Gas6 | Alliance of Genome Resources | ||||
| stroke | FCGR2A*, FCGR2B, FCGR2C | Fcgr2b, Fcgr3 | Alliance of Genome Resources | ||||
| stroke | HMGCR* | Hmgcr | Alliance of Genome Resources | ||||
| stroke | HMOX1* | Hmox1 | Alliance of Genome Resources | ||||
| stroke | HP*, HPR | Hp | Alliance of Genome Resources | ||||
| stroke | IGF1R* | Igf1r | Alliance of Genome Resources | ||||
| stroke | IL1RN* | Il1rn | Alliance of Genome Resources | ||||
| stroke | IL4R* | Il4ra | Alliance of Genome Resources | ||||
| stroke | IL6* | Il6 | Alliance of Genome Resources | ||||
| stroke | ITGA2* | Itga2 | Alliance of Genome Resources | ||||
| stroke | ITGB3* | Itgb3 | Alliance of Genome Resources | ||||
| stroke | KIF6* | Kif6 | Alliance of Genome Resources | ||||
| stroke | KL* | Kl | Alliance of Genome Resources | ||||
| stroke | KNG1* | Kng1, Kng2 | Alliance of Genome Resources | ||||
| stroke | LDLR* | Ldlr | Alliance of Genome Resources | ||||
| stroke | LPA* | ||||||
| stroke | MMP1* | Mmp1a, Mmp1b | Alliance of Genome Resources | ||||
| stroke | MMP9* | Mmp9 | Alliance of Genome Resources | ||||
| stroke | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| stroke | MYH15* | Myh15 | Alliance of Genome Resources | ||||
| stroke | NDUFC2*, NDUFC2-KCTD14 | Ndufc2 | Alliance of Genome Resources | ||||
| stroke | NOS3* | Nos3 | Alliance of Genome Resources | ||||
| stroke | NPPA* | Nppa | Alliance of Genome Resources | ||||
| stroke | PDE4D* | Pde4d | Alliance of Genome Resources | ||||
| stroke | PLAT* | Plat | Alliance of Genome Resources | ||||
| stroke | PON2* | Pon2 | Alliance of Genome Resources | ||||
| stroke | PROZ* | Proz | Alliance of Genome Resources | ||||
| stroke | PTGS2* | Ptgs2 | Alliance of Genome Resources | ||||
| stroke | RETN* | Retn | Alliance of Genome Resources | ||||
| stroke | RNLS* | Rnls | Alliance of Genome Resources | ||||
| stroke | SCNN1A* | Scnn1a | Alliance of Genome Resources | ||||
| stroke | SELL* | Sell | Alliance of Genome Resources | ||||
| stroke | THBD* | Thbd | Alliance of Genome Resources | ||||
| stroke | TNF* | Tnf | Alliance of Genome Resources | ||||
| stroke | UCP2* | Ucp2 | Alliance of Genome Resources | ||||
| stroke | VCAM1* | Vcam1 | Alliance of Genome Resources | ||||
| stroke | ABCC8* | Abcc8 | Alliance of Genome Resources | ||||
| stroke | ACE* | Ace | Alliance of Genome Resources | ||||
| stroke | ADAMTS2* | Adamts2 | Alliance of Genome Resources | ||||
| stroke | ADAMTS12* | Adamts12 | Alliance of Genome Resources | ||||
| stroke | AGER* | Ager | Alliance of Genome Resources | ||||
| stroke | AGT* | Agt | Alliance of Genome Resources | ||||
| stroke | AGXT2* | Agxt2 | Alliance of Genome Resources | ||||
| stroke | ALOX5AP* | Alox5ap | Alliance of Genome Resources | ||||
| stroke | APOH* | Apoh | Alliance of Genome Resources | ||||
| stroke | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| stroke | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
| stroke | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| transient cerebral ischemia | ERCC1* | Ercc1 | Alliance of Genome Resources | ||||
| transient cerebral ischemia | F12* | F12 | Alliance of Genome Resources | ||||
| transient cerebral ischemia | GOT1* | Got1 | Alliance of Genome Resources | ||||
| transient cerebral ischemia | IL1RN* | Il1rn | Alliance of Genome Resources | ||||
| transient cerebral ischemia | LTC4S* | Ltc4s | Alliance of Genome Resources | ||||
| transient cerebral ischemia | NAMPT* | Nampt | Alliance of Genome Resources | ||||
| transient cerebral ischemia | NRG1* | Nrg1 | Alliance of Genome Resources | ||||
| transient cerebral ischemia | SERPINF1* | Serpinf1 | Alliance of Genome Resources | ||||
| transient cerebral ischemia | SOD1* | Sod1 | Alliance of Genome Resources | ||||
| transient cerebral ischemia | TFPI* | Tfpi | Alliance of Genome Resources | ||||
| transient cerebral ischemia | BCL2L2* | Bcl2l2 | Alliance of Genome Resources | ||||
| transient cerebral ischemia | CSF3* | Csf3 | Alliance of Genome Resources | ||||
| transient cerebral ischemia | EPO* | Epo | Alliance of Genome Resources | ||||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| arteriovenous malformations of the brain | Tg(tetO-Notch4*)1Rwng | 1 model | |
| brain ischemia | Tg(Notch3*R169C)88Bbb | 1 model | |