Mammalian Phenotype Ontology Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

53 genotypes with 65 annotations displayed of selected term and subterms
Searched Term: abnormal antigen presentation via MHC class II
Allelic Composition (Genetic Background)	Annotated Term	Reference
\Arfgap2^{tm1c(EUCOMM)Hmgu}/\Arfgap2^{tm1c(EUCOMM)Hmgu} \Tg(CAG-cre/Esr1)5Amc/0 (involves: 129S4/SvJae C57BL/6J * C57BL/6N)	decreased level of surface class II molecules	J:363611
\Cd74^tm1Doi/\Cd74^tm1Doi (either: (involves: 129/Sv * B10.BR) or (involves: 129/Sv * C57BL/6))	abnormal level of surface class II molecules	J:45185
\Cd74^tm1Eae/\Cd74^tm1Eae (involves: 129S2/SvPas)	abnormal level of surface class II molecules	J:65917
\Cd74^tm1Liz/\Cd74^tm1Liz (involves: 129S/SvEv * C57BL/6J)	abnormal antigen presentation via MHC class II	J:65918
	abnormal level of surface class II molecules	J:65918
	defective assembly of class II molecules	J:65918
\Cd74^tm1Liz/\Cd74^tm1Liz (B6.129S-Cd74^tm1Liz)	abnormal antigen presentation via MHC class II	J:28966
	abnormal level of surface class II molecules	J:28966
	defective assembly of class II molecules	J:28966
\Cd74^tm1Liz/\Cd74^tm1Liz (involves: 129S/SvEv * C57BL/6)	abnormal antigen presentation via MHC class II	J:111565
\Cd74^tm1Liz/\Cd74^tm1Liz (involves: 129S/SvEv * BALB/cAn)	abnormal antigen presentation via MHC class II	J:110927, J:113714
\Cd74^tm1Liz/\Cd74^tm1Liz (involves: 129S/SvEv * BALB/c * C57BL)	abnormal antigen presentation via MHC class II	J:110927
\Cd74^tm1Liz/\Cd74^tm1Liz (involves: 129S/SvEv * C57BL * C57BL/10 * C57BR)	abnormal antigen presentation via MHC class II	J:110927
\Cd74^tm1Liz/\Cd74^tm1Liz \H2-DMa^tm1Luc/\H2-DMa^tm1Luc \Tg(CD74)AR194Ayr/? (involves: 129S/SvEv * 129S4/SvJae * C57BL/6J * DBA/2J)	abnormal antigen presentation via MHC class II	J:88717
\Cd74^tm1Liz/\Cd74^tm1Liz \H2-DMa^tm1Luc/\H2-DMa^tm1Luc \Tg(CD74)1Ayr/0 (involves: 129S/SvEv 129S4/SvJae * C57BL/6J * DBA/2J)	abnormal antigen presentation via MHC class II	J:88717
\Cd74^tm2Liz/\Cd74^tm1Liz (involves: 129S/SvEv * C57BL/6)	abnormal antigen presentation via MHC class II	J:28966
\Cd74^tm3Liz/\Cd74^tm3Liz (involves: 129S/SvEv * C57BL/6)	abnormal antigen presentation via MHC class II	J:82880
	abnormal level of surface class II molecules	J:82880
	defective assembly of class II molecules	J:82880
\Ciita^tm1.1Dim/\Ciita^tm1.1Dim (involves: 129S2/SvPas * C57BL/6 * SJL)	abnormal level of surface class II molecules	J:51885
\Ciita^tm1Ccum/\Ciita^tm1Ccum (involves: 129S2/SvPas * C57BL/6J)	abnormal level of surface class II molecules	J:31601, J:96421
	abnormal MHC II cell surface expression on macrophages	J:31601
\Ciita^tm1Ccum/\Ciita^tm1Ccum (NOD.129S2(B6)-Ciita^tm1Ccum)	abnormal level of surface class II molecules	J:106081
\Ciita^tm1Ccum/\Ciita^tm1Ccum (involves: 129S2/SvPas * C57BL/6)	abnormal level of surface class II molecules	J:67941
\Csf2^tm1Ard/\Csf2^tm1Ard (involves: 129P2/OlaHsd * C57BL/6)	abnormal MHC II cell surface expression on macrophages	J:86386
\H2-Aa^b-tm1Blt/\H2-Aa^b-tm1Blt (C57BL/6-H2-Aa^b-tm1Blt)	abnormal MHC II cell surface expression on macrophages	J:67924
\H2-Ab1^b-tm1Gru/\H2-Ab1^b-tm1Gru (involves: 129S2/SvPas * C57BL/6)	abnormal level of surface class II molecules	J:67941
\H2-Ab1^b-tm1Koni/\H2-Ab1^b-tm1.1Koni \Tg(Tek-cre)12Flv/0 (involves: 129X1/SvJ * C3H * C57BL/6 * C57BL/6J)	decreased level of surface class II molecules	J:131774
\H2-Ab1^bm12/\H2-Ab1^bm12 (B6(C)-H2-Ab1^bm12/KhEgJ)	abnormal level of surface class II molecules	J:100194
\H2-Ab1^bm12/\H2-Ab1^bm12 (NZB.B6(C)-H2-Ab1^bm12)	abnormal level of surface class II molecules	J:104189
\H2-DMa^tm1Liz/\H2-DMa^tm1Liz (involves: BALB/cJ)	abnormal antigen presentation via MHC class II	J:113714
\H2-DMa^tm1Liz/\H2-DMa^tm1Liz (involves: BALB/cJ)	defective assembly of class II molecules	J:113714
\H2-DMa^tm1Luc/\H2-DMa^tm1Luc (involves: 129S4/SvJae)	abnormal antigen presentation via MHC class II	J:31625
\H2-DMa^tm1Luc/\H2-DMa^tm1Luc (involves: 129S4/SvJae)	abnormal level of surface class II molecules	J:45185
\H2-DMa^tm1Luc/\H2-DMa^tm1Luc \Cd74^tm1Doi/\Cd74^tm1Doi (involves: 129S2/SvPas * 129S4/SvJae * C57BL/6)	abnormal level of surface class II molecules	J:45185
\H2-DMa^tm2Liz/\H2-DMa^tm2Liz (involves: C57BL/6 * C57BL/10 * C57BR * CBA)	abnormal antigen presentation via MHC class II	J:111565
\H2-Oa^tm1Dma/\H2-Oa^tm1Dma (involves: 129/Sv * C57BL/6)	abnormal antigen presentation via MHC class II	J:65235
\H2-Oa^tm1Lkar/\H2-Oa^tm1Lkar (involves: 129P2/OlaHsd)	abnormal antigen presentation via MHC class II	J:85084
\H2-Ob^em1Tvg/\H2-Ob^em1Tvg (C57BL/6J-H2-Ob^em1Tvg/Tvg)	defective assembly of class II molecules	J:254532
\Ifng^tm1Ts/\Ifng^tm1Ts (involves: 129S7/SvEvBrd * C57BL/6)	abnormal MHC II cell surface expression on macrophages	J:66802
\Il2^tm1Hor/\Il2^tm1Hor (involves: 129P2/OlaHsd * C57BL/6)	abnormal level of surface class II molecules	J:15223
\Il10^tm1Cgn/\Il10^tm1Cgn (involves: 129P2/OlaHsd * C57BL/6)	abnormal level of surface class II molecules	J:15222
\Lyn^tm1Ard/\Lyn^tm1Ard (involves: 129P2/OlaHsd)	abnormal level of surface class II molecules	J:161523
\Lyst^bg-J/\Lyst^bg-J \Prkdc^scid/\Prkdc^scid (B6.Cg-Lyst^bg-J Prkdc^scid/Sz)	abnormal level of surface class II molecules	J:34814
\Marchf1^tm1.1Sish/\Marchf1^tm1.1Sish (involves: 129S1/Sv * 129X1/SvJ)	abnormal level of surface class II molecules	J:119918
\Nup98^tm1Bmaf/\Nup98⁺ (involves: 129S6/SvEvTac * C57BL/6)	abnormal level of surface class II molecules	J:110907
\Nup98^tm1Bmaf/\Nup98⁺ (involves: 129S6/SvEvTac * C57BL/6)	abnormal MHC II cell surface expression on macrophages	J:110907
\Prkdc^scid/\Prkdc^scid (B6.Cg-Prkdc^scid/Sz)	abnormal level of surface class II molecules	J:34814
\Rag1^tm1Mom/\Rag1^tm1Mom (NOD.129S7(B6)-Rag1^tm1Mom)	abnormal level of surface class II molecules	J:109843
\Rag1^tm1Mom/\Rag1^tm1Mom \Prf1^tm1Sdz/\Prf1^tm1Sdz (NOD.Cg-Rag1^tm1Mom Prf1^tm1Sdz/Sz)	abnormal level of surface class II molecules	J:109843
\Rfx5^tm1.1Ifo/\Rfx5^tm1.1Ifo (involves: 129 * C57BL/6)	abnormal level of surface class II molecules	J:67941
\Rfx5^tm1.1Ifo/\Rfx5^tm1.1Ifo (involves: 129 * C57BL/6)	abnormal MHC II cell surface expression on macrophages	J:67941
\Rfx5^tm1Ifo/\Rfx5^tm1.1Ifo \Lyz2^tm1(cre)Ifo/\Lyz2⁺ (involves: 129 * C57BL/6 * C.B-20)	abnormal MHC II cell surface expression on macrophages	J:67924
\Stat1^tm1Dlv/\Stat1^tm1Dlv (involves: 129S/SvEv)	abnormal MHC II cell surface expression on macrophages	J:130622
\Stat1^tm1Tdec/\Stat1^tm1Tdec (involves: 129P2/OlaHsd * BALB/c)	abnormal MHC II cell surface expression on macrophages	J:130622
\Stat2^p117/\Stat2^p117 (C57BL/6J-Stat2^P117)	abnormal level of surface class II molecules	J:164049
\Stat6^tm1Jni/\Stat6^tm1Jni (involves: 129S/SvEv)	abnormal level of surface class II molecules	J:32607
\Sting1^gt/\Sting1^gt (C57BL/6J-Sting1^gt/J)	abnormal MHC II cell surface expression on macrophages	J:363611
\Tg(H2-Aa)26Dim/? \Tg(H2-Ab1)62Dim/? (B6.Cg-Tg(H2-Aa)26Dim Tg(H2-Ab1)62Dim)	abnormal antigen presentation via MHC class II	J:110897
	abnormal level of surface class II molecules	J:110897
\Tg(H2-Aa)26Dim/? \Tg(H2-Ab1)62Dim/? (SJL.Cg-Tg(H2-Aa)26Dim Tg(H2-Ab1)62Dim)	abnormal level of surface class II molecules	J:110897
\Tg(Igh-6-Cd80)1Gjf/0 (NOD.FVB-Tg(Igh-6-Cd80)1Gjf/JbsJ)	abnormal level of surface class II molecules	J:131077
\Tirap^tm1Aki/\Tirap^tm1Aki (involves: 129P2/OlaHsd * C57BL/6)	abnormal level of surface class II molecules	J:111205
\Tlr4^tm1Aki/\Tlr4^tm1Aki (involves: 129P2/OlaHsd * C57BL/6)	abnormal level of surface class II molecules	J:76115
\Unc93b1^3d/\Unc93b1^3d (C57BL/6J-Unc93b1^3d)	abnormal antigen presentation via MHC class II	J:105484

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24