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Human Disease and Mouse Model Detail
Human Disease Rheumatoid Arthritis; RA
OMIM ID: 180300
Human Phenotype Ontology associations
Synonyms Rheumatoid Arthritis; Rheumatoid Arthritis, Susceptibility to
View all models View ALL (17) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Disease is associated/modeled with this Gene or a homolog. More...
      Human Homologs Mouse Homologs Mouse Models Homology Source
     DNASE2 Dnase2a* View 2 models HomoloGene and HGNC
IL6ST Il6st* View 1 model HomoloGene and HGNC
MMP14 Mmp14* View 1 model HomoloGene and HGNC
TNF Tnf* View 5 models HomoloGene and HGNC
ZAP70 Zap70* View 1 model HomoloGene and HGNC
ZFP36 Zfp36* View 1 model HomoloGene and HGNC
     CD244* Cd244   HomoloGene and HGNC
CIITA* Ciita   HomoloGene and HGNC
HLA-DRB1*   HomoloGene
IL10* Il10   HomoloGene and HGNC
NFKBIL1* Nfkbil1   HomoloGene and HGNC
PADI4* Padi4   HomoloGene and HGNC
PTPN22* Ptpn22   HomoloGene and HGNC
SLC22A4* Slc22a4   HomoloGene and HGNC
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Tg(CAG-SYVN1)1Tn View 1 model
  Tg(FCGR2A)11Mkz View 1 model
  Tg(HLA-DRA*0101,HLA-DRB1*0101)1Dmz View 1 model
  Tg(TcraR28,TcrbR28)KRNDim View 2 models
  Tg(TNF)197Gkl View 1 model
  Tg(TNF)3647Gkl View 1 model
References Disease References using Mouse Models (22)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.07
The Jackson Laboratory