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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Fgfr2
fibroblast growth factor receptor 2
MGI:95523
389 phenotypes from 28 alleles in 38 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
En1tm2(cre)Wrst/En1+
Fgfr2tm1Wrst/Fgfr2tm1Wrst
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		normal nervous system phenotype J:118802
Fgfr2hob/Fgfr2hob
involves: C57BL/6J 		absent limbs J:216825
lethality throughout fetal growth and development J:216825
primary sex reversal J:216825
pulmonary hypoplasia J:216825
Fgfr2m1Sgg/Fgfr2+
involves: C3H/HeJ * C57BL/6J 		abnormal basisphenoid bone morphology J:160674
abnormal chondrocyte morphology J:160674
abnormal craniofacial morphology J:160674
abnormal ear development J:160674
abnormal endochondral bone ossification J:160674
abnormal nasal septum cartilage morphology J:160674
abnormal palatal shelf fusion at midline J:160674
abnormal sternum morphology J:160674
absent presphenoid bone J:160674
cleft secondary palate J:160674
decreased birth body size J:160674
decreased cranium height J:160674
decreased embryo size J:160674
decreased osteoblast cell number J:160674
domed cranium J:160674
normal growth/size/body region phenotype J:160674
long incisors J:160674
malocclusion J:160674
premature coronal suture closure J:160674
short snout J:160674
wide cranial sutures J:160674
Fgfr2m1Sgg/Fgfr2m1Sgg
involves: C3H/HeJ * C57BL/6J 		abnormal basisphenoid bone morphology J:160674
abnormal chondrocyte morphology J:160674
abnormal cranial cartilage morphology J:160674
abnormal cranium morphology J:160674
abnormal digestive system morphology J:160674
abnormal ear development J:160674
abnormal endochondral bone ossification J:160674
abnormal limb development J:160674
abnormal nasal capsule morphology J:160674
abnormal nasal septum cartilage morphology J:160674
abnormal palate development J:160674
abnormal palatine bone horizontal plate morphology J:160674
abnormal sternum manubrium morphology J:160674
abnormal sternum morphology J:160674
abnormal tongue morphology J:160674
abnormal vertebrae morphology J:160674
abnormal xiphoid process morphology J:160674
abnormal zygomatic arch morphology J:160674
absent apical ectodermal ridge J:160674
absent lacrimal glands J:160674
absent limbs J:160674
absent presphenoid bone J:160674
absent submandibular gland J:160674
arrest of tooth development J:160674
cervical vertebral fusion J:160674
decreased brain size J:160674
decreased embryo size J:160674
decreased osteoblast cell number J:160674
delayed cranial suture closure J:160674
exophthalmos J:160674
impaired lung lobe morphogenesis J:160674
neonatal lethality J:160674
respiratory distress J:160674
shallow orbits J:160674
short snout J:160674
small frontal bone J:160674
small kidney J:160674
small lung J:160674
small pancreas J:160674
small parietal bone J:160674
split sternum J:160674
thick nasal septum J:160674
vertebral fusion J:160674
wide cranial sutures J:160674
Fgfr2svs/Fgfr2svs
either: CXB1/By or CXB1/ByEss * CXB1/ByLac 		abnormal seminal vesicle morphology J:9441
Fgfr2svs/Fgfr2svs
involves: CXB5/ByJ 		abnormal prostate gland branching morphogenesis J:82767
abnormal seminal vesicle development J:82767
abnormal seminal vesicle morphology J:82767
abnormal seminal vesicle muscle layer morphology J:82767
decreased prostate gland duct number J:82767
increased prostate gland weight J:82767
Fgfr2tm1.1Dor/Fgfr2hob
involves: 129X1/SvJ * C57BL/6J * FVB/N 		absent limbs J:216825
decreased fetal size J:216825
primary sex reversal J:216825
pulmonary hypoplasia J:216825
Fgfr2tm1.1Dor/Fgfr2svs
involves: 129X1/SvJ * CXB5/ByJ * FVB/N 		abnormal branching involved in seminal vesicle morphogenesis J:119935
Fgfr2tm1.1Dor/Fgfr2tm1.1Dor
involves: 129X1/SvJ 		abnormal placenta development J:90391
absent limb buds J:90391
embryonic lethality during organogenesis, complete penetrance J:90391
Fgfr2tm1.1Dsn/Fgfr2+
involves: 129P2/OlaHsd * C57BL/6 		abnormal submandibular duct morphology J:119849
submandibular gland hypoplasia J:119849
Fgfr2tm1.1Dsn/Fgfr2tm1.1Dsn
involves: 129P2/OlaHsd 		abnormal lateral nasal gland morphology J:237227
abnormal nasal gland morphology J:237227
abnormal palatal mesenchymal cell proliferation J:90909
abnormal palate morphology J:90909
abnormal pancreas development J:82083
abnormal secondary palate development J:90909
abnormal tongue morphology J:90909
absent palatal rugae J:90909
cleft secondary palate J:90909
normal craniofacial phenotype J:145189
decreased palatal length J:90909
palatal shelf fusion with tongue or mandible J:90909
small pancreas J:82083
tongue ankylosis J:90909
Fgfr2tm1.1Dsn/Fgfr2tm1.1Dsn
involves: 129P2/OlaHsd * C57BL/6 		abnormal cecum development J:87411
abnormal clavicle morphology J:59285
abnormal cochlea morphology J:72516
abnormal cochlear sensory epithelium morphology J:72516
abnormal endolymphatic duct morphology J:59285, J:72516
abnormal epidermis stratum basale morphology J:59285, J:109476
abnormal ilium morphology J:59285
abnormal ischium morphology J:59285
abnormal limb development J:59285
abnormal lung development J:59285
abnormal mammary gland bud morphology J:73434
abnormal mammary placode morphology J:109476
abnormal membranous labyrinth morphology J:72516
abnormal otic capsule morphology J:72516
abnormal pelvic girdle bone morphology J:59285
abnormal perineum morphology J:92361
abnormal pituitary gland development J:59285
abnormal Rathke's pouch apoptosis J:59285
abnormal Rathke's pouch development J:59285
abnormal rectum morphology J:92361
abnormal salivary gland morphology J:59285
abnormal semicircular canal morphology J:59285, J:72516
abnormal stomach morphology J:59285
abnormal vestibulocochlear ganglion morphology J:72516
absent acromion J:59285
absent adenohypophysis J:59285
absent eyelids J:59285
absent forelimb J:59285, J:92361
absent hindlimb J:59285, J:92361
absent hypodermis muscle layer J:59285
absent lungs J:59285, J:92361
absent mammary gland J:73434
absent pubis J:59285
absent Rathke's pouch J:59285
absent rectum J:92361
absent submandibular gland J:119849
arrest of tooth development J:59285
caudal vertebral fusion J:59285
cecal atresia J:92361
cleft palate J:59285
curly tail J:59285, J:92361
decreased body size J:59285
decreased skin pigmentation J:59285
domed cranium J:59285
impaired branching involved in trachea morphogenesis J:59285
inner ear cyst J:59285
perinatal lethality, complete penetrance J:59285
perineal hypospadia J:92361
premature squamoparietal suture closure J:59285
small otic capsule J:59285
small otic vesicle J:72516
small scapula J:59285
small stomach J:59285
submandibular gland hypoplasia J:119849
thin dermal layer J:59285
thin epidermis J:59285
thin skin J:59285
translucent skin J:59285
Fgfr2tm1.1Wrst/Fgfr2tm1.1Wrst
involves: BALB/c * C57BL/6 		abnormal embryo development J:118802
embryonic lethality between implantation and somite formation, complete penetrance J:118802
Fgfr2tm1Cxd/Fgfr2+
either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * NIH Black Swiss) 		no abnormal phenotype detected J:46380
Fgfr2tm1Cxd/Fgfr2tm1Cxd
either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * NIH Black Swiss) 		abnormal placenta development J:46380
abnormal placenta morphology J:46380
abnormal placenta vasculature J:46380
abnormal spongiotrophoblast layer morphology J:46380
abnormal trophoblast layer morphology J:46380
absent limb buds J:46380
absent placental labyrinth J:46380
decreased embryo size J:46380
embryonic growth retardation J:46380
embryonic lethality during organogenesis, complete penetrance J:46380
enlarged allantois J:46380
failure of chorioallantoic fusion J:46380
increased trophoblast giant cell number J:46380
small otic vesicle J:46380
Fgfr2tm1Dor/Fgfr2svs
involves: 129X1/SvJ * CXB5/ByJ * FVB/N 		normal endocrine/exocrine gland phenotype J:119935
Fgfr2tm1Dor/Fgfr2tm1.1Dor
Twist2tm1(cre)Dor/Twist2+
involves: 129X1/SvJ 		abnormal appendicular skeleton morphology J:90391
abnormal axial skeleton morphology J:90391
abnormal cervical vertebrae morphology J:90391
abnormal joint morphology J:90391
abnormal long bone hypertrophic chondrocyte zone J:90391
abnormal long bone metaphysis morphology J:90391
abnormal osteoblast physiology J:90391
abnormal osteoclast differentiation J:90391
abnormal skeleton development J:90391
abnormal thoracic vertebrae morphology J:90391
abnormal vertebrae development J:90391
abnormal vertebrae morphology J:90391
absent vertebral spinous process J:90391
decreased bone mineral density J:90391
decreased cell proliferation J:90391
decreased osteoblast cell number J:90391
disproportionate dwarf J:90391
domed cranium J:90391
postnatal growth retardation J:90391
short femur J:90391
Fgfr2tm1Dor/Fgfr2tm1Dor
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129X1/SvJ * C57BL/6J * CBA/J 		normal vision/eye phenotype J:130571
Fgfr2tm1Dor/Fgfr2tm1Dor
Tg(GFAP-cre)25Mes/0
involves: 129X1/SvJ * FVB/N 		abnormal astrocyte morphology J:110263
abnormal brain morphology J:110263
Fgfr2tm1Dor/Fgfr2tm1Dor
Tg(KRT5-cre)5132Jlj/0
involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J 		abnormal coat/ hair morphology J:158802
decreased sebaceous gland number J:158802
progressive hair loss J:158802
Fgfr2tm1Dor/Fgfr2tm1Dor
Tg(Mnx1-cre)1Jrs/?
involves: 129X1/SvJ * C57BL/6 		abnormal synaptic vesicle clustering J:126496
decreased body size J:126496
tremors J:126496
Fgfr2tm1Dor/Fgfr2tm1Dor
Tg(Pax6-cre,GFP)1Pgr/0
involves: 129X1/SvJ * FVB 		abnormal lacrimal gland development J:130571
absent lacrimal gland bud J:130571
absent lacrimal glands J:130571
Fgfr2tm1Dor/Fgfr2tm1Dor
Tg(Sftpc-cre)1Blh/0
involves: 129X1/SvJ * C57BL/6 * DBA/2 		abnormal lung development J:150706
decreased embryo size J:150706
impaired branching involved in bronchus morphogenesis J:150706
Fgfr2tm1Dsn/Fgfr2tm1Dsn
Tg(KRT5-cre)5132Jlj/0
involves: 129P2/OlaHsd * C57BL/6J * DBA/2J 		abnormal epidermal layer morphology J:119723
abnormal hair cycle J:119723
abnormal hair follicle morphology J:119723
abnormal hair follicle orientation J:119723
abnormal nail morphology J:119723
abnormal zigzag hair morphology J:119723
adipose tissue inflammation J:119723
epidermal cyst J:119723
increased gamma-delta T cell number J:119723
increased incidence of tumors by chemical induction J:119723
increased keratinocyte proliferation J:119723
increased skin papilloma incidence J:119723
parakeratosis J:119723
sebaceous gland atrophy J:119723
skin inflammation J:119723
thick epidermis J:119723
Fgfr2tm1Ewj/Fgfr2+
Tg(EIIa-cre)C5379Lmgd/0
B6.Cg-Fgfr2tm1Ewj Tg(EIIa-cre)C5379Lmgd 		abnormal coronal suture morphology J:158773
abnormal cranial suture morphology J:158773
abnormal intermaxillary suture morphology J:158773
abnormal maxillary-premaxillary suture morphology J:158773
abnormal palatal shelf fusion at midline J:158773
abnormal palate morphology J:158773
decreased inner canthal distance J:158773
decreased palatal length J:158773
enhanced osteoblast differentiation J:158773
increased cranium height J:158773
increased osteoblast proliferation J:158773
premature coronal suture closure J:158773
premature zygomaticomaxillary suture closure J:158773
short mandible J:158773
short maxilla J:158773
short nasal bone J:158773
small cranium J:158773
Fgfr2tm1Ewj/Fgfr2+
Tg(EIIa-cre)C5379Lmgd/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N 		abnormal basicranium morphology J:101174
abnormal brain morphology J:156940
abnormal cartilage development J:101174
abnormal cartilage morphology J:101174
abnormal cerebral hemisphere morphology J:156940
abnormal corpus callosum morphology J:156940
abnormal cranial suture morphology J:101174
abnormal craniofacial bone morphology J:101174
abnormal head shape J:101174
abnormal interparietal bone morphology J:101174
abnormal long bone hypertrophic chondrocyte zone J:101174
abnormal mandible morphology J:101174
abnormal mandibular angle morphology J:101174
abnormal maxillary frontal process morphology J:101174
abnormal maxillary zygomatic process morphology J:101174
abnormal nasal bone morphology J:101174
abnormal osteoblast differentiation J:101174
abnormal palate morphology J:101174
abnormal sagittal suture morphology J:101174
abnormal thymus morphology J:101174
abnormal tracheal cartilage morphology J:101174
abnormal vasodilation J:101174
abnormal zygomatic arch morphology J:101174
aerophagia J:101174
atelectasis J:101174
bronchiolectasis J:101174
decreased birth weight J:101174
decreased body length J:101174
decreased body weight J:101174
decreased cranium height J:101174
decreased cranium length J:101174
decreased osteoclast cell number J:101174
dilated heart atrium J:101174
enlarged fourth ventricle J:156940
hydrocephaly J:101174
increased brain size J:156940
meteorism J:101174
neonatal lethality, complete penetrance J:101174
parietal bossing J:101174
premature coronal suture closure J:101174, J:156940
premature cranial suture closure J:101174
premature lambdoid suture closure J:101174
pulmonary alveolar proteinosis J:101174
respiratory failure J:101174
short maxilla J:101174
shortened head J:101174
small cranium J:101174
small face J:101174
small mandible J:101174
small neurocranium J:101174
wide metopic suture J:101174
Fgfr2tm1Lni/Fgfr2tm1Lni
involves: 129S1/Sv * 129X1/SvJ * MF1 		abnormal decidualization J:47643
abnormal developmental patterning J:47643
abnormal egg cylinder morphology J:47643
abnormal endoderm development J:47643
absent blastocoele J:47643
absent primitive endoderm J:47643
normal embryo phenotype J:47643
embryonic lethality between implantation and somite formation, complete penetrance J:47643
inner cell mass degeneration J:47643
Fgfr2tm1Schl/Fgfr2+
involves: 129S1/Sv 		abnormal cranium morphology J:118299
exophthalmos J:118299
premature coronal suture closure J:118299
premature cranial suture closure J:118299
short face J:118299
Fgfr2tm1Schl/Fgfr2tm1Schl
involves: 129S1/Sv 		abnormal respiration J:118299
abnormal tracheal cartilage morphology J:118299
cleft palate J:118299
fused joints J:118299
neonatal lethality, complete penetrance J:118299
palatal shelves fail to meet at midline J:118299
Fgfr2tm1Wrst/Fgfr2tm1Wrst
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		no abnormal phenotype detected J:118802
Fgfr2tm2.1Lni/Fgfr2tm2.1Lni
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 		absent limbs J:77698
absent lungs J:77698
absent submandibular gland J:77698
neonatal lethality, complete penetrance J:77698
Fgfr2tm2.1Lni/Fgfr2tm2.1Lni
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal synaptic vesicle clustering J:126496
abnormal synaptic vesicle number J:126496
neonatal lethality, complete penetrance J:126496
Fgfr2tm2.2Dsn/Fgfr2+
involves: 129 * C57BL/6 * FVB/N 		no abnormal phenotype detected J:72517
Fgfr2tm2.3Dsn/Fgfr2+
involves: 129 * C57BL/6 * FVB/N 		abnormal bronchiole morphology J:72517
abnormal intestinal glucose absorption J:72517
abnormal kidney cortex morphology J:72517
abnormal liver development J:72517
abnormal lung morphology J:72517
abnormal neurocranium morphology J:72517
abnormal pulmonary acinus morphology J:72517
abnormal right lung morphology J:72517
abnormal sternebra morphology J:72517
abnormal sternum ossification J:72517
abnormal zygomatic arch morphology J:72517
absent exorbital lacrimal gland J:72517
decreased body size J:72517
decreased nephron number J:72517
decreased renal glomerulus number J:72517
normal digestive/alimentary phenotype J:72517
dilated distal convoluted tubule J:72517
dilated proximal convoluted tubule J:72517
domed cranium J:72517
normal endocrine/exocrine gland phenotype J:72517
exophthalmos J:72517
hypoglycemia J:72517
impaired lung alveolus development J:72517
impaired lung lobe morphogenesis J:72517
postnatal growth retardation J:72517
postnatal lethality, complete penetrance J:72517
premature coronal suture closure J:72517
shallow orbits J:72517
short maxilla J:72517
short snout J:72517
small kidney J:72517
small lung J:72517
split sternal manubrium J:72517
split xiphoid process J:72517
Fgfr2tm2Cxd/Fgfr2+
Tg(EIIa-cre)C5379Lmgd/0
involves: 129S6/SvEvTac * C57BL/6J * FVB/N 		abnormal palatine bone morphology J:228708
abnormal presphenoid bone morphology J:228708
abnormal trabecular bone morphology J:228708
abnormal zygomatic arch morphology J:228708
domed cranium J:228708
midface hypoplasia J:228708
premature coronal suture closure J:228708
premature facial suture closure J:228708
premature frontonasal suture closure J:228708
premature maxillary-premaxillary suture closure J:228708
premature palatomaxillary suture closure J:228708
short nasal bone J:228708
wide intermaxillary suture J:228708
Fgfr2tm2Cxd/Fgfr2+
Tg(EIIa-cre)C5379Lmgd/0
involves: 129S6/SvEvTac * FVB/N 		abnormal cranial suture morphology J:101385
abnormal craniofacial morphology J:101385
abnormal cranium morphology J:101385
abnormal long bone epiphyseal plate proliferative zone J:101385
abnormal neurocranium morphology J:101385
abnormal sagittal suture morphology J:101385
decreased cranium height J:101385
decreased embryo size J:101385
domed cranium J:101385
female infertility J:101385
malocclusion J:101385
midface hypoplasia J:101385
ocular hypertelorism J:101385
postnatal lethality, incomplete penetrance J:101385
premature coronal suture closure J:101385
premature cranial suture closure J:101385
reduced male fertility J:101385
short presphenoid bone J:101385
thin frontal bone J:101385
thin parietal bone J:101385
Fgfr2tm2Dsn/Fgfr2+
Tg(Pgk1-cre)1Lni/0
involves: 129 * 129X1/SvJ * BALB/c * C57BL/6 		submandibular gland hypoplasia J:119849
Fgfr2tm2Dsn/Fgfr2tm2Dsn
involves: 129 * C57BL/6 		no abnormal phenotype detected J:72517
Fgfr2tm2Ewj/Fgfr2+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal brain morphology J:156940
abnormal cerebral hemisphere morphology J:156940
abnormal corpus callosum morphology J:156940
enlarged fourth ventricle J:156940
enlarged lateral ventricles J:156940
premature coronal suture closure J:156940
Fgfr2tm2Ewj/Fgfr2+
Tg(EIIa-cre)C5379Lmgd/0
B6.Cg-Fgfr2tm2Ewj Tg(EIIa-cre)C5379Lmgd 		abnormal cranial suture morphology J:158773
abnormal lambdoid suture morphology J:158773
abnormal maxillary zygomatic process morphology J:158773
abnormal palatal shelf fusion at midline J:158773
abnormal sagittal suture morphology J:158773
abnormal skeleton development J:158773
abnormal skeleton physiology J:158773
abnormal sternum morphology J:158773
abnormal zygomatic bone morphology J:158773
decreased body weight J:158773
decreased inner canthal distance J:158773
decreased palatal length J:158773
domed cranium J:158773
enhanced osteoblast differentiation J:158773
increased cranium height J:158773
increased osteoblast proliferation J:158773
postnatal growth retardation J:158773
postnatal lethality, complete penetrance J:158773
premature coronal suture closure J:158773
short basicranium J:158773
short femur J:158773
short humerus J:158773
short mandible J:158773
short maxilla J:158773
short nasal bone J:158773
short radius J:158773
short tibia J:158773
small cranium J:158773
synostosis J:158773
Fgfr2tm2Schl/Fgfr2+
involves: 129S1/Sv * BALB/c * C57BL/6 		no abnormal phenotype detected J:118299
Fgfr2tm2Schl/Fgfr2tm2Schl
involves: 129S1/Sv * BALB/c * C57BL/6 		abnormal tracheal cartilage morphology J:118299
cleft palate J:118299
palatal shelves fail to meet at midline J:118299
Fgfr2tm3.1Cxd/Fgfr2+
involves: 129S6/SvEvTac * FVB/N 		abnormal cranial cartilage development J:283626
abnormal cranial synchondrosis J:283626
abnormal craniofacial morphology J:283626
abnormal cranium morphology J:283626
abnormal endochondral bone ossification J:283626
abnormal long bone epiphyseal ossification zone morphology J:283626
abnormal long bone epiphyseal plate proliferative zone J:283626
abnormal long bone epiphysis morphology J:283626
abnormal midface morphology J:283626
abnormal synchondrosis J:283626
abnormal trabecular bone morphology J:283626
normal cardiovascular system phenotype J:283626
decreased body size J:283626
decreased body weight J:283626
decreased cranium length J:283626
decreased width of hypertrophic chondrocyte zone J:283626
delayed cranial suture closure J:283626
domed cranium J:283626
enhanced osteoblast differentiation J:283626
increased cranium height J:283626
increased cranium width J:283626
malocclusion J:283626
midface hypoplasia J:283626
ocular hypertelorism J:283626
postnatal growth retardation J:283626
postnatal lethality, incomplete penetrance J:283626
premature coronal suture closure J:283626
premature death J:283626
premature intramembranous bone ossification J:283626
normal respiratory system phenotype J:283626
short basicranium J:283626
short rostral-caudal axis J:283626
shortened head J:283626
syndactyly J:283626
Fgfr2tm3.1Lni/Fgfr2tm3.1Lni
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 		abnormal basicranium morphology J:77698
abnormal basisphenoid bone morphology J:77698
abnormal coronal suture morphology J:77698
abnormal facial morphology J:77698
abnormal head morphology J:77698
abnormal nasomaxillary suture morphology J:77698
abnormal osteoblast proliferation J:77698
abnormal presphenoid bone morphology J:77698
abnormal sphenoid bone morphology J:77698
decreased body size J:77698
decreased body weight J:77698
decreased cranium height J:77698
decreased width of hypertrophic chondrocyte zone J:77698
delayed bone ossification J:77698
domed cranium J:77698
exophthalmos J:77698
postnatal growth retardation J:77698
premature coronal suture closure J:77698
premature cranial suture closure J:77698
normal renal/urinary system phenotype J:167305
slow postnatal weight gain J:77698
Fgfr2tm3Cxd/Fgfr2+
Tg(Nes-cre)1Kln/0
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL 		abnormal brain size J:286452
abnormal cranium morphology J:286452
short nasal bone J:286452
Fgfr2tm3Cxd/Fgfr2+
Tg(Col2a1-cre)1Xya/0
involves: 129S6/SvEvTac * C57BL/6J 		abnormal basicranium morphology J:286452
abnormal basioccipital bone morphology J:286452
abnormal basisphenoid bone morphology J:286452
abnormal cranial cavity morphology J:286452
abnormal cranium morphology J:286452
abnormal frontal bone morphology J:286452
abnormal maxillary frontal process morphology J:286452
abnormal midface morphology J:286452
abnormal nasal bone morphology J:286452
abnormal neurocranium morphology J:286452
abnormal sphenooccipital synchondrosis J:286452
decreased bone volume J:286452
decreased cranium length J:286452
ocular hypertelorism J:286452
premature coronal suture closure J:286452
premature presphenoid synchondrosis closure J:286452
premature sphenooccipital synchondrosis closure J:286452
shallow orbits J:286452
short frontal bone J:286452
short maxilla J:286452
short nasal bone J:286452
short premaxilla J:286452
short zygomatic arch J:286452
short zygomatic bone J:286452
wide metopic suture J:286452
wide sagittal suture J:286452
Fgfr2tm3Dsn/Fgfr2tm3Dsn
involves: 129P2/OlaHsd * C57BL/6 		abnormal adrenal gland development J:67731
abnormal apical ectodermal ridge morphology J:67731
abnormal conotruncal ridge morphology J:111148
abnormal epidermal layer morphology J:85732
abnormal epidermis stratum basale morphology J:85732
abnormal hair follicle development J:85732
abnormal hair follicle morphology J:67731, J:85732
abnormal heart development J:111148
abnormal heart ventricle morphology J:111148
abnormal interventricular groove morphology J:111148
abnormal keratinocyte morphology J:85732
abnormal kidney development J:67731
abnormal otic vesicle development J:67731
abnormal pancreas development J:67731
abnormal pelvic girdle bone morphology J:67731
abnormal pulmonary circulation J:111148
abnormal salivary gland morphology J:67731
abnormal scapula morphology J:67731
abnormal skin morphology J:67731
abnormal stomach glandular region morphology J:67731
abnormal thymus development J:67731
abnormal trabecula carnea morphology J:111148
abnormal truncus arteriosus septation J:111148
abnormal urethra morphology J:98380
abnormal vibrissa number J:85732
absent adenohypophysis J:67731
absent eyelids J:67731
absent limbs J:67731
absent lungs J:67731
absent pulmonary artery J:111148
absent pulmonary vein J:111148
absent teeth J:67731
absent thyroid gland J:67731
caudal vertebral fusion J:67731
cleft palate J:67731
conotruncal ridge hypoplasia J:111148
curly tail J:67731
decreased fetal size J:67731
decreased hair follicle number J:85732
decreased nephron number J:67731
delayed intramembranous bone ossification J:67731
double outlet right ventricle J:111148
heart left atrium hypoplasia J:111148
heart right ventricle hypoplasia J:111148
hypospadia J:98380
muscular ventricular septal defect J:111148
overriding aortic valve J:111148
perimembraneous ventricular septal defect J:111148
perinatal lethality, complete penetrance J:67731
small kidney J:67731
small otic capsule J:67731
thin epidermis J:85732
thin left ventricle myocardium compact layer J:111148
thin skin J:67731, J:85732
thin ventricular wall J:111148
Fgfr2tm3Ewj/Fgfr2+
B6.129-Fgfr2tm3Ewj 		abnormal dermis papillary layer morphology J:190491
abnormal epidermis stratum basale morphology J:190491
abnormal epidermis stratum corneum morphology J:190491
abnormal head shape J:190491
abnormal skin morphology J:190491
abnormal sternum morphology J:190491
abnormal umbilical cord morphology J:190491
acanthosis J:190491
epidermal hyperplasia J:190491
epidermis stratum granulosum hyperplasia J:190491
epidermis stratum spinosum hyperplasia J:190491
midface hypoplasia J:190491
postnatal growth retardation J:190491
postnatal lethality, complete penetrance J:190491
premature coronal suture closure J:190491
premature cranial suture closure J:190491
premature squamoparietal suture closure J:190491
premature zygomaticomaxillary suture closure J:190491
shortened head J:190491
thick epidermis J:190491
Fgfr2tm3Lni/Fgfr2tm3Lni
involves: 129S1/Sv * 129X1/SvJ 		abnormal urethra morphology J:94932
absent limbs J:94932
Fgfr2tm4Lni/Fgfr2+
Not Specified 		abnormal frontal bone morphology J:235329
abnormal sphenoid bone morphology J:92433
decreased molar number J:92433
domed cranium J:92433
exophthalmos J:92433
increased osteoblast cell number J:92433
malocclusion J:92433
ocular hypertelorism J:92433
premature coronal suture closure J:92433, J:235329
premature cranial suture closure J:92433
short face J:92433
short maxilla J:92433
Fgfr2tm4Lni/Fgfr2tm4Lni
Not Specified 		abnormal appendicular skeleton morphology J:92433
abnormal axial skeleton morphology J:92433
abnormal basicranium morphology J:92433
abnormal bone ossification J:92433
abnormal lung morphology J:92433
abnormal nasal bone morphology J:92433
abnormal osteoblast physiology J:92433
abnormal palatal shelf fusion at midline J:92433
abnormal palatine bone morphology J:92433
abnormal sternebra morphology J:92433
cleft secondary palate J:92433
domed cranium J:92433
eyelids open at birth J:92433
fused tracheal cartilage rings J:92433
increased osteoblast cell number J:92433
neonatal lethality, complete penetrance J:92433
respiratory failure J:92433
short basicranium J:92433
short face J:92433
vertebral fusion J:92433
Tg(Pbsn-Fgfr2/Fkbp1a)#Dmsp/0
FVB-Tg(Pbsn-Fgfr2/Fkbp1a)#Dmsp 		normal endocrine/exocrine gland phenotype J:87092
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory