Fgfr2tm2.3Dsn
Targeted Allele Detail
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Symbol: |
Fgfr2tm2.3Dsn |
Name: |
fibroblast growth factor receptor 2; targeted mutation 2.3, Clive Dickson |
MGI ID: |
MGI:2153817 |
Synonyms: |
Fgfr2delta, FgfR2-IIIcdelta |
Gene: |
Fgfr2 Location: Chr7:129764181-129868538 bp, - strand Genetic Position: Chr7, 73.19 cM
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Alliance: |
Fgfr2tm2.3Dsn page
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Growth retardation in Fgfr2tm2.3Dsn/Fgfr2+ mice
Show the 3 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:72517
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: This allele is a derivative of Fgfr2tm2Dsn in which both the exon 9 sequences and the neomycin and thymidine kinase sequences were deleted by crossing mice carrying the Fgfr2tm2Dsn allele to mice which expresss Cre recombinase in the germ line.
(J:72517)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Fgfr2 Mutation: |
88 strains or lines available
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Original: |
J:72517 Hajihosseini MK, et al., A splicing switch and gain-of-function mutation in FgfR2-IIIc hemizygotes causes Apert/Pfeiffer-syndrome-like phenotypes. Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3855-60 |
All: |
4 reference(s) |
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