Agrntm1Rwb/Agrntm1Rwb
Tg(APPswe,PSEN1dE9)85Dbo/?
Tg(Tek-cre)1Ywa/?
involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 * SJL
|
amyloid beta deposits |
J:220073
|
Agrntm5Jrs/Agrntm5Jrs
Tg(APPswe,PSEN1dE9)85Dbo/?
involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 * FVB/N
|
normal
nervous system phenotype |
J:220073
|
Aplp1tm1Umu/Aplp1tm1Umu
Apptm2Cwe/Apptm2Cwe
involves: 129/Sv * 129P2/OlaHsd * C57BL/6
|
decreased body weight |
J:65196
|
Aplp2tm1Dbo/Aplp2tm1Dbo
Apptm1.1Zhe/Apptm1.1Zhe
Chattm2(cre)Lowl/Chat+
involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6J
|
abnormal neuromuscular synapse morphology |
J:152457
|
Aplp2tm1Dbo/Aplp2tm1Dbo
Apptm1.1Zhe/Apptm1.1Zhe
Tg(Ckmm-cre)5Khn/0
involves: 129S7/SvEvBrd * C57BL/6J * FVB
|
abnormal miniature endplate potential |
J:152457
|
|
abnormal neuromuscular synapse morphology |
J:152457
|
Aplp2tm1Dbo/Aplp2tm1Dbo
Apptm1.1Zhe/Apptm1.1Zhe
Tg(Nes-cre)1Kln/0
involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL
|
abnormal miniature endplate potential |
J:152457
|
|
abnormal neuromuscular synapse morphology |
J:152457
|
Aplp2tm1Dbo/Aplp2tm1Dbo
Apptm1.2Zhe/Apptm1.2Zhe
involves: 129S7/SvEvBrd * C57BL/6J
|
abnormal neuromuscular synapse morphology |
J:152457
|
Aplp2tm1Dbo/Aplp2tm1Dbo
Apptm1.2Zhe/Apptm2.1Zhe
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ
|
postnatal lethality, complete penetrance |
J:165417
|
Aplp2tm1Dbo/Aplp2tm1Dbo
Apptm1Dbo/Apptm1Dbo
involves: 129/Sv * 129X1/SvJ * C57BL/6
|
postnatal lethality, complete penetrance |
J:166379
|
Aplp2tm1Dbo/Aplp2tm1Dbo
Apptm1Dbo/Apptm1Dbo
involves: 129S7/SvEvBrd * C57BL/6J
|
abnormal neuromuscular synapse morphology |
J:207796
|
|
absent gastric milk in neonates |
J:45851
|
|
ataxia |
J:45851
|
|
decreased body size |
J:45851
|
|
head tilt |
J:45851
|
|
impaired righting response |
J:45851
|
|
pallor |
J:45851
|
|
postnatal lethality, incomplete penetrance |
J:45851
|
|
reduced fertility |
J:45851
|
|
spinning |
J:45851
|
|
weakness |
J:45851
|
Aplp2tm1Dbo/Aplp2tm1Dbo
Apptm1Dbo/Apptm3.1Zhe
involves: 129/Sv * 129X1/SvJ * C57BL/6
|
abnormal neuromuscular synapse morphology |
J:166379
|
|
postnatal lethality, incomplete penetrance |
J:166379
|
Aplp2tm1Dbo/Aplp2tm1Dbo
Apptm2.1Zhe/Apptm2.1Zhe
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ
|
abnormal neuromuscular synapse morphology |
J:165417
|
|
postnatal lethality, complete penetrance |
J:165417
|
Aplp2tm1Dbo/Aplp2tm1Dbo
Apptm2Cwe/Apptm2Cwe
involves: 129/Sv * 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J
|
postnatal lethality, complete penetrance |
J:65196
|
Aplp2tm1Dbo/Aplp2tm1Dbo
Apptm3.1Zhe/Apptm3.1Zhe
involves: 129/Sv * 129X1/SvJ * C57BL/6
|
abnormal neuromuscular synapse morphology |
J:166379
|
|
postnatal lethality, incomplete penetrance |
J:166379
|
Apmaptm1a(KOMP)Wtsi/Apmaptm1a(KOMP)Wtsi
Tg(APPswe,PSEN1dE9)85Dbo/0
involves: C57BL/6J * C57BL/6N
|
abnormal spatial reference memory |
J:273177
|
|
amyloid beta deposits |
J:273177
|
Apptm1.1Cep/Apptm1.1Cep
Psen1tm1Dgf/Psen1tm1Dgf
involves: 129S1/Sv * 129X1/SvJ * CD-1
|
amyloid beta deposits |
J:66147,
J:102425
|
Apptm1Ck/Apptm1Ck
Psen1tm1Mpm/Psen1tm1Mpm
involves: 129 * 129S1/Sv * 129X1/SvJ
|
abnormal brain morphology |
J:191170
|
|
abnormal spatial working memory |
J:191170
|
|
amyloid beta deposits |
J:166379
|
|
enhanced contextual conditioning behavior |
J:191170
|
|
increased anxiety-related response |
J:191170
|
|
increased circulating corticosterone level |
J:191170
|
Apptm1Ck/Apptm1Ck
Psen1tm1Mpm/Psen1tm1Mpm
Tg(MAPT)8cPdav/0
B6.Cg-Tg(MAPT)8cPdav Psen1tm1Mpm Apptm1Ck
|
amyloid beta deposits |
J:209782
|
|
decreased locomotor activity |
J:209782
|
|
enhanced contextual conditioning behavior |
J:209782
|
|
increased anxiety-related response |
J:209782
|
|
increased fear-related response |
J:209782
|
|
tau protein deposits |
J:209782
|
Apptm1Ck/Apptm1Ck
Tg(PDGFB-PSEN1)1Jhd/0
involves: 129 * Black Swiss * C57BL/6 * DBA/2 * SW
|
abnormal cholinergic neuron morphology |
J:102542
|
Apptm1Ck/Apptm1Ck
Tg(PDGFB-PSEN1M146L)2Jhd/0
involves: 129 * Black Swiss * C57BL/6 * DBA/2 * SW
|
abnormal cholinergic neuron morphology |
J:102542,
J:102879
|
|
abnormal microglial cell morphology |
J:102542
|
|
amyloid beta deposits |
J:102542,
J:102879
|
|
increased astrocyte number |
J:102542
|
Apptm1Dbo/App+
Lrp4tm1Her/Lrp4tm1Her
involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6J
|
premature death |
J:207796
|
Apptm1Dbo/App+
Dab1tm1Bwh/Dab1tm1Bwh
involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6
|
small cerebellum |
J:132599
|
Apptm1Dbo/Apptm1Dbo
Dab1tm1Bwh/Dab1tm1Bwh
involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6
|
small cerebellum |
J:132599
|
Apptm1Dbo/Apptm1Dbo
Lrp4tm1Her/Lrp4+
involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6J
|
premature death |
J:207796
|
Apptm1Dbo/Apptm1Dbo
Lrp4tm1Her/Lrp4tm1Her
involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6J
|
abnormal neuromuscular synapse morphology |
J:207796
|
|
abnormal neuron differentiation |
J:207796
|
|
preweaning lethality, incomplete penetrance |
J:207796
|
Apptm1Dbo/Apptm1Dbo
Npc1m1N/Npc1m1N
C.Cg-Apptm1Dbo Npc1m1N
|
astrocytosis |
J:172769
|
|
decreased brain size |
J:172769
|
|
demyelination |
J:172769
|
|
impaired coordination |
J:172769
|
|
increased brain cholesterol level |
J:172769
|
|
premature death |
J:172769
|
|
Purkinje cell degeneration |
J:172769
|
|
weight loss |
J:172769
|
Apptm1Sud/Apptm1Sud
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
no abnormal phenotype detected |
J:133653
|
Apptm1Umu/Apptm1Umu
involves: 129P2/OlaHsd * C57BL/6
|
normal
behavior/neurological phenotype |
J:123316
|
|
normal
growth/size/body region phenotype |
J:123316
|
|
normal
nervous system phenotype |
J:123316
|
Apptm2.1Tcs/Apptm2.1Tcs
Casttm1Tcs/Casttm1Tcs
involves: 129P2/OlaHsd * C57BL/6
|
abnormal learning/memory/conditioning |
J:212758
|
|
amyloid beta deposits |
J:212758
|
|
amyloidosis |
J:212758
|
|
astrocytosis |
J:212758
|
|
microgliosis |
J:212758
|
Apptm3.1Tcs/Apptm3.1Tcs
Klk7tm1(KOMP)Vlcg/Klk7tm1(KOMP)Vlcg
involves: C57BL/6NTac
|
amyloid beta deposits |
J:261970
|
Apptm3.1Tcs/Apptm3.1Tcs
Mapttm1.1(MAPT)Tcs/Mapttm1.1(MAPT)Tcs
involves: 129S/SvEv * C57BL/6
|
amyloid beta deposits |
J:278451
|
|
CNS inflammation |
J:278451
|
|
increased neuron apoptosis |
J:278451
|
Apptm3.1Zhe/Apptm3.1Zhe
Psen1tm1Mpm/Psen1tm1Mpm
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
|
amyloid beta deposits |
J:166379
|
Gt(ROSA)26Sortm1(H1/tetO-RNAi:Pion)Pggd/Gt(ROSA)26Sor+
Tg(APPswe,PSEN1dE9)85Dbo/0
involves: 129S6/SvEvTac * C3H * C57BL/6
|
amyloid beta deposits |
J:163997
|
Hc1/Hc1
Tg(APPswe,PSEN1dE9)85Dbo/0
D2.Cg-Tg(APPswe,PSEN1dE9)85Dbo
|
amyloid beta deposits |
J:227541
|
|
convulsive seizures |
J:227541
|
|
normal
nervous system phenotype |
J:227541
|
|
premature death |
J:227541
|
Itm2btm1.1Ldad/Itm2b+
Tg(APPswe,PSEN1dE9)85Dbo/0
involves: 129 * C3H * C57BL/6
|
abnormal nervous system physiology |
J:138796
|
Leprdb/Lepr+
Tg(APPswe,PSEN1dE9)85Dbo/0
involves: C3H * C57BL/6 * C57BLKS/J
|
abnormal circulating cholesterol level |
J:186924
|
|
amyloidosis |
J:186924
|
|
normal
growth/size/body region phenotype |
J:186924
|
|
impaired glucose tolerance |
J:186924
|
|
increased circulating glucose level |
J:186924
|
|
increased circulating insulin level |
J:186924
|
|
increased pancreatic beta cell mass |
J:186924
|
|
insulin resistance |
J:186924
|
Lrrtm3tm1Msa/Lrrtm3tm1Msa
Tg(APPswe,PSEN1dE9)85Dbo/0
involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6JHsd
|
normal
homeostasis/metabolism phenotype |
J:262456
|
Map2k4tm1Ctr/Map2k4tm1Ctr
Map2k7tm1Rjd/Map2k7tm1Rjd
Tg(APPswe,PSEN1dE9)85Dbo/0
Tg(Camk2a-cre/ERT2)2Gsc/0
involves: C3H * C57BL/6 * FVB/N
|
abnormal neurite morphology |
J:178060
|
|
amyloid beta deposits |
J:178060
|
Nr1h2tm1Djm/Nr1h2tm1Djm
Tg(APPswe,PSEN1dE9)85Dbo/0
involves: 129S6/SvEvTac * C3H * C57BL/6
|
amyloid beta deposits |
J:122372
|
Nr1h3tm1Djm/Nr1h3tm1Djm
Tg(APPswe,PSEN1dE9)85Dbo/0
involves: 129S6/SvEvTac * C3H * C57BL/6
|
amyloid beta deposits |
J:122372
|
Omptm1(tTA)Gogo/Omp+
Tg(tetO-APPSwInd)Dbo/0
involves: 129 * C3H/HeJ * C57BL/6J
|
abnormal olfactory bulb glomerular layer morphology |
J:199798
|
|
abnormal olfactory bulb morphology |
J:199798
|
|
abnormal olfactory bulb outer nerve layer morphology |
J:199798
|
|
abnormal olfactory epithelium morphology |
J:176127
|
|
abnormal olfactory sensory neuron morphology |
J:199798
|
|
abnormal olfactory sensory neuron physiology |
J:176127
|
|
abnormal synaptic bouton morphology |
J:199798
|
|
decreased olfactory sensory neuron number |
J:176127
|
|
impaired olfaction |
J:199798
|
|
neurodegeneration |
J:176127
|
|
small olfactory bulb |
J:199798
|
Omptm1(tTA)Gogo/Omptm2(spH)Mom
Tg(tetO-APPSwInd)Dbo/0
involves: 129 * 129P2/OlaHsd * C3H/HeJ * C57BL/6J
|
impaired olfaction |
J:199798
|
Or8a1tm25Mom/Or8a1+
Omptm1(tTA)Gogo/Omp+
Tg(tetO-APPSwInd)Dbo/0
involves: 129 * C3H/HeJ * C57BL/6J
|
decreased olfactory sensory neuron number |
J:199798
|
Or10a4tm1Mom/Or10a4+
Omptm1(tTA)Gogo/Omp+
Tg(tetO-APPSwInd)Dbo/0
involves: 129 * 129P2/OlaHsd * C3H/HeJ * C57BL/6J
|
abnormal olfactory bulb layer morphology |
J:199798
|
|
decreased olfactory sensory neuron number |
J:199798
|
Prnptm2Edin/Prnptm2Edin
Tg(APPswe,PSEN1dE9)85Dbo/0
B6.Cg-Prnptm2Edin Tg(APPswe,PSEN1dE9)85Dbo
|
amyloid beta deposits |
J:160557
|
|
astrocytosis |
J:160557
|
|
normal
behavior/neurological phenotype |
J:160557
|
|
normal
mortality/aging |
J:160557
|
|
normal
nervous system phenotype |
J:160557
|
Ptger2tm1Brey/Ptger2tm1Brey
Tg(APPswe,PSEN1dE9)85Dbo/0
involves: 129S6/SvEvTac * C3H * C57BL/6
|
abnormal nervous system physiology |
J:102728
|
|
amyloidosis |
J:102728
|
Rtn4rl2tm1Yanr/Rtn4rl2tm1Yanr
Tg(APPswe,PSEN1dE9)85Dbo/0
involves: 129S6/SvEvTac * C3H * C57BL/6 * C57BL/6J
|
amyloid beta deposits |
J:175718
|
Tg(APPswe,PSEN1dE9)85Dbo/0
B6.Cg-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax
|
abnormal CNS synaptic transmission |
J:234430
|
|
abnormal spatial learning |
J:160557,
J:172426
|
|
amyloid beta deposits |
J:160557,
J:172426,
J:208080,
J:227541
|
|
astrocytosis |
J:160557
|
|
axon degeneration |
J:160557
|
|
convulsive seizures |
J:227541
|
|
impaired contextual conditioning behavior |
J:234430
|
|
impaired passive avoidance behavior |
J:160557
|
|
impaired spatial learning |
J:234430
|
|
premature death |
J:160557
|
|
reduced long-term potentiation |
J:234430
|
|
normal
taste/olfaction phenotype |
J:172426
|
Tg(APPswe,PSEN1dE9)85Dbo/0
B6;C3-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax
|
abnormal spatial learning |
J:129021
|
|
amyloid beta deposits |
J:113199,
J:113200,
J:129021
|
|
amyloidosis |
J:129021
|
|
blood vessel congestion |
J:113200
|
|
cerebral amyloid angiopathy |
J:113200
|
|
impaired glucose tolerance |
J:129021
|
|
increased body weight |
J:129021
|
|
increased circulating cholesterol level |
J:129021
|
|
increased circulating insulin level |
J:129021
|
|
increased circulating triglyceride level |
J:113199
|
|
increased fluid intake |
J:129021
|
Tg(APPswe,PSEN1dE9)85Dbo/0
CAST.Cg-Tg(APPswe,PSEN1dE9)85Dbo/How
|
cerebral amyloid angiopathy |
J:276728
|
Tg(APPswe,PSEN1dE9)85Dbo/0
D2.Cg-Tg(APPswe,PSEN1dE9)85Dbo
|
amyloid beta deposits |
J:227541
|
|
convulsive seizures |
J:227541
|
|
microgliosis |
J:227541
|
|
normal
nervous system phenotype |
J:227541
|
|
premature death |
J:227541
|
Tg(APPswe,PSEN1dE9)85Dbo/0
involves: C3H * C57BL/6
|
abnormal medium spiny neuron morphology |
J:145530
|
|
amyloidosis |
J:186924
|
|
decreased neuron number |
J:145530
|
|
normal
homeostasis/metabolism phenotype |
J:186924
|
|
normal
nervous system phenotype |
J:145530
|
|
neuron degeneration |
J:145530
|
Tg(APPswe,PSEN1dE9)85Dbo/0
involves: C3H/HeH * C57BL/6JNju
|
abnormal action potential |
J:275175
|
|
abnormal asymmetric synapse morphology |
J:275175
|
|
abnormal olfactory behavior |
J:275175
|
|
abnormal olfactory bulb external plexiform layer morphology |
J:275175
|
|
abnormal olfactory bulb granule cell morphology |
J:275175
|
|
abnormal postsynaptic density morphology |
J:275175
|
|
abnormal spatial reference memory |
J:275175
|
|
abnormal symmetric synapse morphology |
J:275175
|
|
abnormal synapse morphology |
J:275175
|
|
abnormal synaptic transmission |
J:275175
|
|
abnormal synaptic vesicle morphology |
J:275175
|
|
amyloid beta deposits |
J:275175
|
|
decreased dendritic spine density |
J:275175
|
|
impaired spatial learning |
J:275175
|
Tg(APPswe,PSEN1dE9)85Dbo/0
involves: C3H/HeJ * C57BL/6J
|
abnormal spatial reference memory |
J:139071
|
|
amyloid beta deposits |
J:87691,
J:139071
|
|
decreased body weight |
J:139071
|
|
impaired coordination |
J:139071
|
|
reduced long-term potentiation |
J:139071
|
Tg(APPswe,PSEN1dE9)85Dbo/0
WSB.Cg-Tg(APPswe,PSEN1dE9)85Dbo/How
|
cerebral amyloid angiopathy |
J:276728
|
|
impaired blood-brain barrier function |
J:276728
|
Tg(APPswe,PSEN1dE9)85Dbo/?
Tg(MGS1-19375/CFP)2R9Rwb/?
involves: C3H * C57BL/6 * C57BL/6J
|
amyloid beta deposits |
J:220073
|
Tg(Camk2a-App*,-Apbb1)25Spim/0
C57BL/6-Tg(Camk2a-App*,-Apbb1)25Spim
|
abnormal spatial working memory |
J:153738
|
|
normal
behavior/neurological phenotype |
J:153738
|
|
increased susceptibility to neuronal excitotoxicity |
J:153738
|
|
neurodegeneration |
J:153738
|
|
tau protein deposits |
J:153738
|
Excel File
Analysis Tools