359 phenotypes from 22 alleles in 50 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Chd7Coa1/Chd7+ involves: C57BL/6J	abnormal brain development	J:187010
	abnormal corpus callosum morphology	J:187010
	abnormal embryonic neuroepithelium morphology	J:187010
	abnormal eye morphology	J:187010
	abnormal frontal lobe morphology	J:187010
	abnormal hippocampus morphology	J:187010
	abnormal neocortex morphology	J:187010
	abnormal olfactory lobe morphology	J:187010
	abnormal parietal lobe morphology	J:187010
	abnormal telencephalon development	J:187010
	abnormal telencephalon morphology	J:187010
	absent hippocampus	J:187010
	absent olfactory bulb	J:187010
	circling	J:187010
	decreased body size	J:187010
	decreased body weight	J:187010
	dilated lateral ventricle	J:187010
	dilated third ventricle	J:187010
	head bobbing	J:187010
	hydrocephaly	J:187010
	hyperactivity	J:187010
	impaired hearing	J:187010
	lethality throughout fetal growth and development, incomplete penetrance	J:187010
	postnatal growth retardation	J:187010
	premature death	J:187010
	preweaning lethality, incomplete penetrance	J:187010
	reduced fertility	J:187010
	small hippocampus	J:187010
	small olfactory bulb	J:187010
Chd7Coa1/Chd7Coa1 involves: C57BL/6J	embryonic lethality during organogenesis, complete penetrance	J:187010
Chd7Cycn/Chd7+ involves: BALB/c * C3H/HeN	abnormal lateral semicircular canal morphology	J:75619
	abnormal posterior semicircular canal morphology	J:75619
	circling	J:63816
	decreased body size	J:75619
	head tossing	J:75619
Chd7Dz/Chd7+ involves: BALB/c * C3H/HeN	abnormal lateral semicircular canal morphology	J:75619
	abnormal posterior semicircular canal morphology	J:75619
	circling	J:63816
	decreased body size	J:75619
	head tossing	J:75619
Chd7Edy/Chd7+ involves: BALB/c * C3H/HeN	abnormal incudomalleolar joint morphology	J:75619
	abnormal incus morphology	J:75619
	abnormal lateral semicircular canal morphology	J:75619
	abnormal malleus morphology	J:75619
	abnormal posterior semicircular canal morphology	J:75619
	abnormal stapes crus morpholgy	J:75619
	abnormal stapes morphology	J:75619
	circling	J:63816
	decreased body size	J:75619
	decreased cochlear nerve compound action potential	J:75619
	head tossing	J:75619
Chd7em1Jiao/Chd7em1Jiao involves: 129S6/SvEvTac * C57BL/6 * SJL	embryonic growth arrest	J:298597
	embryonic growth retardation	J:298597
	embryonic lethality during organogenesis, complete penetrance	J:298597
Chd7em1Kangn/Chd7em1Kangn Tg(Prrx1-cre)1Cjt/0 involves: C57BL/6J * SJL/J	abnormal bone marrow cell physiology	J:336448
	abnormal compact bone morphology	J:336448
	abnormal craniofacial bone morphology	J:336448
	abnormal trabecular bone morphology	J:336448
	decreased body size	J:336448
	decreased body weight	J:336448
	decreased bone mass	J:336448
	decreased bone mineral density	J:336448
	decreased bone mineralization	J:336448
	decreased bone ossification	J:336448
	decreased bone trabecula number	J:336448
	decreased femur compact bone thickness	J:336448
	decreased long bone epiphyseal plate size	J:336448
	decreased osteoblast cell number	J:336448
	decreased trabecular bone thickness	J:336448
	decreased volumetric bone mineral density	J:336448
	increased bone marrow adipose tissue amount	J:336448
	increased bone trabecular spacing	J:336448
	premature death	J:336448
	short limbs	J:336448
Chd7em1Kangn/Chd7em1Kangn Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 involves: C57BL/6J * CD-1	abnormal compact bone morphology	J:336448
	abnormal trabecular bone morphology	J:336448
	decreased body size	J:336448
	decreased body weight	J:336448
	decreased bone mass	J:336448
	decreased bone mineralization	J:336448
	decreased bone ossification	J:336448
	decreased osteoblast cell number	J:336448
	increased bone marrow adipose tissue amount	J:336448
	premature death	J:336448
Chd7Flo/Chd7+ C3HeB/FeJ-Chd7Flo	abnormal lateral semicircular canal morphology	J:93173
	abnormal motor coordination/balance	J:93173
	abnormal placing response	J:93173
	abnormal round window morphology	J:93173
	abnormal stapes footplate morphology	J:93173
	abnormal stapes morphology	J:93173
	abnormal stationary movement	J:93173
	circling	J:93173
	head bobbing	J:93173
	impaired righting response	J:93173
	impaired swimming	J:93173
	increased cochlear outer hair cell number	J:93173
Chd7Flo/Chd7+ involves: C3HeB/FeJ	abnormal external female genitalia morphology	J:104123
	clitoris hypoplasia	J:104123
	dry eyes	J:104123
	keratoconjunctivitis sicca	J:104123
	postnatal lethality	J:104123
Chd7Gt(RRR136)Byg/Chd7+ involves: 129P2/OlaHsd * C57BL/6	abnormal cardiac outflow tract development	J:154590
	abnormal common carotid artery morphology	J:154590
	abnormal fourth pharyngeal arch artery morphology	J:154590
	abnormal pharyngeal arch artery morphology	J:154590
	abnormal sixth pharyngeal arch artery morphology	J:154590
	aortic arch coarctation	J:154590
	circling	J:154590
	ectopic thymus	J:154590
	small thymus	J:154590
	thymus hypoplasia	J:154590
Chd7Gt(RRR136)Byg/Chd7Gt(RRR136)Byg involves: 129P2/OlaHsd * C57BL/6	embryonic lethality, complete penetrance	J:154590
Chd7Gt(S20-7E1)Sor/Chd7+ 129S1.129S4(B6)-Chd7Gt(S20-7E1)Sor	abnormal estrous cycle	J:174086
	abnormal hypothalamus physiology	J:174086
	abnormal neurohypophysis median eminence morphology	J:174086
	abnormal neuron differentiation	J:174086
	abnormal neuron physiology	J:148116
	abnormal olfactory epithelium cilium morphology	J:148116
	abnormal olfactory epithelium morphology	J:148116
	abnormal olfactory epithelium physiology	J:148116
	abnormal olfactory sensory neuron morphology	J:148116
	abnormal olfactory sensory neuron physiology	J:148116
	abnormal olfactory system physiology	J:174086
	abnormal pituitary gland physiology	J:174086
	abnormal telencephalon morphology	J:148116
	decreased apoptosis	J:174086
	decreased body size	J:174086
	decreased brain size	J:148116
	decreased cell proliferation	J:174086
	decreased circulating follicle stimulating hormone level	J:174086
	decreased circulating luteinizing hormone level	J:174086
	decreased neuron number	J:174086
	decreased olfactory sensory neuron number	J:148116
	delayed estrous cycle	J:174086
	delayed sexual maturation	J:174086
	delayed vaginal opening	J:174086
	normal endocrine/exocrine gland phenotype	J:174086
	normal homeostasis/metabolism phenotype	J:174086
	impaired olfaction	J:148116
	olfactory bulb hypoplasia	J:148116
Chd7Gt(S20-7E1)Sor/Chd7+ B6;129S-Chd7Gt(S20-7E1)Sor/DmmJ	abnormal semicircular canal morphology	J:314662
	decreased retina cone cell number	J:331474
	short retina cone cell outer segment	J:331474
	short retina rod cell outer segment	J:331474
Chd7Gt(S20-7E1)Sor/Chd7+ either: (involves: 129S4/SvJae * C57BL/6J) or (involves: 129S1/SvImJ * 129S4/SvJae C57BL/6J)	abnormal common crus morphology	J:123608
	abnormal crista ampullaris morphology	J:123608
	abnormal crista ampullaris neuroepithelium morphology	J:123608
	abnormal lateral semicircular canal morphology	J:123608
	abnormal posterior semicircular canal morphology	J:123608
	abnormal semicircular canal morphology	J:123608
	abnormal sensory neuron innervation pattern	J:123608
	abnormal vestibular nerve morphology	J:123608
	absent posterior semicircular canal	J:123608
	bidirectional circling	J:123608
	decreased lateral semicircular canal size	J:123608
Chd7Gt(S20-7E1)Sor/Chd7+ involves: 129S1/SvImJ * 129S4/SvJae	abnormal CNS glial cell morphology	J:332873
	abnormal vestibulocochlear ganglion morphology	J:332873
	hypermyelination	J:332873
	increased or absent threshold for auditory brainstem response	J:332873
Chd7Gt(S20-7E1)Sor/Chd7+ involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J	abnormal maternal nurturing	J:119812
	abnormal semicircular canal morphology	J:119812
	absent lateral semicircular canal	J:119812
	absent posterior semicircular canal	J:119812
	circling	J:119812
	decreased body weight	J:119812
	decreased lateral semicircular canal size	J:119812
	decreased posterior semicircular canal size	J:119812
	delayed embryo turning	J:119812
	normal endocrine/exocrine gland phenotype	J:119812
	head bobbing	J:119812
	hyperactivity	J:119812
	postnatal lethality	J:119812
	reduced female fertility	J:119812
Chd7Gt(S20-7E1)Sor/Chd7+ involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J * DBA/2J	abnormal induced morbidity/mortality	J:220430
	abnormal otic capsule morphology	J:220430
	abnormal stapes footplate morphology	J:220430
	abnormal stapes morphology	J:220430
	absent distortion product otoacoustic emissions	J:220430
	conductive hearing impairment	J:220430
	decreased oval window size	J:220430
	decreased round window size	J:220430
	decreased susceptibility to noise-induced hearing loss	J:220430
	impaired hearing	J:220430
	increased cochlear outer hair cell number	J:220430
	increased or absent threshold for auditory brainstem response	J:220430
	sensorineural hearing impairment	J:220430
Chd7Gt(S20-7E1)Sor/Chd7+ involves: 129S4/SvJaeSor	abnormal ear development	J:164582
	abnormal neuronal precursor cell number	J:164582
	abnormal neuronal precursor proliferation	J:164582
	abnormal vestibulocochlear ganglion morphology	J:164582
Chd7Gt(S20-7E1)Sor/Chd7+ involves: 129S4/SvJaeSor * C57BL/6J	abnormal seminiferous tubule morphology	J:329885
	coloboma	J:231044
Chd7Gt(S20-7E1)Sor/Chd7Gt(S20-7E1)Sor 129S1.129S4(B6)-Chd7Gt(S20-7E1)Sor	abnormal nasal placode morphology	J:174086
	abnormal olfactory system physiology	J:174086
	absent nasal pit	J:174086
	decreased cell proliferation	J:174086
Chd7Gt(S20-7E1)Sor/Chd7Gt(S20-7E1)Sor involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J	abnormal embryonic neuroepithelium morphology	J:119812
	abnormal hindlimb morphology	J:119812
	abnormal nasal pit morphology	J:119812
	abnormal optic eminence morphology	J:119812
	abnormal otic vesicle development	J:119812
	abnormal trigeminal ganglion morphology	J:119812
	decreased embryonic neuroepithelium thickness	J:119812
	delayed embryo turning	J:119812
	embryonic lethality during organogenesis, complete penetrance	J:119812
	Rathke's pouch hypoplasia	J:119812
	small otic vesicle	J:119812
Chd7Gt(S20-7E1)Sor/Chd7Gt(S20-7E1)Sor involves: 129S4/SvJaeSor	abnormal ear development	J:164582
	abnormal neuronal precursor cell number	J:164582
	abnormal neuronal precursor proliferation	J:164582
	abnormal vestibulocochlear ganglion morphology	J:164582
Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm involves: 129 * C57BL/6 * Swiss Webster	decreased lateral semicircular canal size	J:164582
Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm Foxg1tm1(cre)Skm/Foxg1+ involves: 129 * C57BL/6 * Swiss Webster	abnormal cochlea morphology	J:164582
	abnormal cochlear sensory epithelium morphology	J:310063
	abnormal crista ampullaris morphology	J:164582
	abnormal ear development	J:164582
	abnormal inner ear vestibule morphology	J:164582
	abnormal neuronal precursor cell number	J:164582
	abnormal neuronal precursor proliferation	J:164582
	abnormal suckling behavior	J:164582
	abnormal vestibulocochlear ganglion morphology	J:164582, J:310063
	absent lateral semicircular canal	J:164582
	absent posterior semicircular canal	J:164582
	absent utricle	J:164582
	absent vestibular saccule	J:164582
	decreased cochlea coiling	J:164582
	decreased superior semicircular canal size	J:164582
	increased cochlear outer hair cell number	J:310063
	neonatal lethality, complete penetrance	J:164582
	ocular hypertelorism	J:164582
	short snout	J:164582
	small endolymphatic duct	J:164582
Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm Tg(Pax2-cre)1Akg/0 involves: 129S * C57BL/6	abnormal cochlea morphology	J:310063
	absent lateral semicircular canal	J:310063
	absent superior semicircular canal	J:310063
Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm Tg(T-cre)1Lwd/0 involves: 129S * C3H * C57BL/6	normal hearing/vestibular/ear phenotype	J:310063
Chd7Gt(XK403)Byg/Chd7+ either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * CD-1)	abnormal fourth pharyngeal arch artery morphology	J:154590
Chd7Gt(XK403)Byg/Chd7+ involves: 129P2/OlaHsd * C57BL/6	abnormal cardiac outflow tract development	J:154590
	abnormal cranial nerve morphology	J:154590
	abnormal fourth pharyngeal arch artery morphology	J:154590
	abnormal neural crest cell migration	J:154590
	abnormal pharyngeal arch artery morphology	J:154590
	abnormal pulmonary trunk morphology	J:154590
	abnormal sixth pharyngeal arch artery morphology	J:154590
	abnormal subclavian artery morphology	J:154590
	abnormal vagus nerve morphology	J:154590
	aorta coarctation	J:154590
	circling	J:154590
	embryonic lethality during organogenesis, incomplete penetrance	J:154590
	fusion of glossopharyngeal and vagus nerve	J:154590
	interrupted aortic arch, type b	J:154590
	postnatal lethality, incomplete penetrance	J:154590
Chd7Gt(XK403)Byg/Chd7+ involves: 129P2/OlaHsd * C57BL/6 * DBA/2	abnormal cerebellar foliation	J:262209
	abnormal cerebellar hemisphere morphology	J:262209
	abnormal cerebellum fissure morphology	J:262209
	abnormal cerebellum hemisphere lobule morphology	J:262209
	abnormal cerebellum vermis lobule morphology	J:262209
	abnormal cerebellum vermis lobule VIII morphology	J:262209
	abnormal cerebral cortex morphology	J:262209
	abnormal lobule simplex morphology	J:262209
	cerebellum hypoplasia	J:262209
	decreased brain size	J:262209
	small cerebellum	J:262209
Chd7Gt(XK403)Byg/Chd7+ involves: 129P2/OlaHsd * C57BL/6J	normal nervous system phenotype	J:207892
Chd7Gt(XK403)Byg/Chd7+ Mesp1tm2(cre)Ysa/Mesp1+ either: (involves: 129P2/OlaHsd * C57BL/6 * CBA) or (involves: 129P2/OlaHsd * C57BL/6 * CBA * CD-1)	abnormal fourth pharyngeal arch artery morphology	J:154590
	abnormal sixth pharyngeal arch artery morphology	J:154590
Chd7Gt(XK403)Byg/Chd7+ H2az2Tg(Wnt1-cre)11Rth/H2az2+ either: (involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA/J) or (involves: 129P2/OlaHsd * C57BL/6J * CBA/J * CD-1)	abnormal fourth pharyngeal arch artery morphology	J:154590
Chd7Gt(XK403)Byg/Chd7+ Tfap2atm1(cre)Moon/Tfap2a+ either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * CD-1)	normal embryo phenotype	J:154590
Chd7Gt(XK403)Byg/Chd7+ Tg(Tbx1-cre)1Joe/0 either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * CD-1)	abnormal fourth pharyngeal arch artery morphology	J:154590
	abnormal sixth pharyngeal arch artery morphology	J:154590
Chd7Gt(XK403)Byg/Chd7Gt(XK403)Byg involves: 129P2/OlaHsd * C57BL/6	embryonic lethality, complete penetrance	J:154590
Chd7Lda/Chd7+ involves: BALB/c * C3H/HeN	abnormal lateral semicircular canal morphology	J:75619
	abnormal posterior semicircular canal morphology	J:75619
	circling	J:75619
	decreased body size	J:75619
	head tossing	J:75619
Chd7Looper/Chd7+ BALB/c-Chd7Looper	abnormal glenoid fossa morphology	J:252089
	abnormal incus long process morphology	J:252089
	abnormal incus morphology	J:252089
	abnormal incus short process morphology	J:252089
	abnormal lateral semicircular canal morphology	J:252089
	abnormal malleus manubrium morphology	J:252089
	abnormal middle ear ossicle morphology	J:252089
	abnormal motor capabilities/coordination/movement	J:252089
	abnormal oval window morphology	J:252089
	abnormal posterior semicircular canal morphology	J:252089
	abnormal stapes footplate morphology	J:252089
	abnormal stapes morphology	J:252089
	abnormal superior semicircular canal morphology	J:252089
	blepharitis	J:252089
	circling	J:252089
	conjunctivitis	J:252089
	decreased body weight	J:252089
	decreased startle reflex	J:252089
	eyelid edema	J:252089
	facial asymmetry	J:252089
	impaired hearing	J:252089
	increased locomotor activity	J:252089
	increased or absent threshold for auditory brainstem response	J:252089
	narrow eye opening	J:252089
	otosclerosis	J:252089
	postnatal growth retardation	J:252089
Chd7Looper/Chd7+ involves: BALB/c * C57BL/6	increased or absent threshold for auditory brainstem response	J:252089
Chd7Mt/Chd7+ involves: BALB/c * C3H/HeN	abnormal lateral semicircular canal morphology	J:75619
	abnormal posterior semicircular canal morphology	J:75619
	circling	J:75619
	decreased body size	J:75619
	head tossing	J:75619
Chd7Obt/Chd7+ involves: BALB/c * C3H/HeN	abnormal inner ear canal fusion	J:75619
	abnormal lateral semicircular canal morphology	J:75619
	abnormal posterior semicircular canal morphology	J:75619
	circling	J:63816
	decreased body size	J:75619
	head tossing	J:75619
Chd7Ome/Chd7+ involves: BALB/cByJ * C57BL/6J	abnormal auditory tube morphology	J:187200
	abnormal distortion product otoacoustic emission	J:187200
	abnormal middle ear epithelium morphology	J:187200
	abnormal stapes footplate morphology	J:187200
	abnormal stapes head morphology	J:187200
	absent cochlear microphonics	J:187200
	circling	J:187200
	decreased body size	J:187200
	decreased body weight	J:187200
	impaired hearing	J:187200
	impaired swimming	J:187200
	increased cranium height	J:187200
	increased middle ear goblet cell number	J:187200
	increased or absent threshold for auditory brainstem response	J:187200
	increased periosteum thickness	J:187200
	increased susceptibility to otitis media	J:187200
	long snout	J:187200
	postnatal growth retardation	J:187200
	reduced male fertility	J:187200
	small stapes obturator foramen	J:187200
Chd7tm1.1Dmm/Chd7+ Foxg1tm1(cre)Skm/Foxg1+ involves: 129 * C57BL/6 * Swiss Webster	abnormal ear development	J:164582
	abnormal vestibulocochlear ganglion morphology	J:164582
	decreased lateral semicircular canal size	J:164582
Chd7tm1.1Dmm/Chd7+ Tg(rx3-icre)1Mjam/0 involves: 129S6/SvEvTac	coloboma	J:231044
Chd7tm1.1Dmm/Chd7tm1.1Dmm Foxg1tm1(cre)Skm/Foxg1+ involves: 129P2/OlaHsd * 129S6/SvEvTac	abnormal lens development	J:231044
	absent optic cup	J:231044
Chd7tm1.1Dmm/Chd7tm1.1Dmm Olig1tm1(cre)Rth/Olig1+ involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6	decreased myelin sheath thickness	J:234565
	decreased oligodendrocyte number	J:234565
	dysmyelination	J:234565
Chd7tm1.1Dmm/Chd7tm1.1Dmm Tg(Pax2-cre)1Akg/0 involves: 129S1/SvImJ * 129S6/SvEvTac * C57BL/6	abnormal cochlea morphology	J:310063
	abnormal cochlear sensory epithelium morphology	J:310063
	abnormal vestibulocochlear ganglion morphology	J:310063
	increased cochlear hair cell number	J:310063
Chd7tm1.1Dmm/Chd7tm1.1Dmm Tg(Pax6-cre,GFP)1Pgr/0 involves: 129S6/SvEvTac * FVB	small lens	J:231044
Chd7tm1.1Dmm/Chd7tm1.1Dmm Tg(Pdgfra-cre/ERT)467Dbe/0 involves: 129S6/SvEvTac * C57BL/6 * SJL	abnormal oligodendrocyte apoptosis	J:264451
	abnormal oligodendrocyte physiology	J:234565, J:264451
	decreased oligodendrocyte progenitor number	J:264451
Chd7tm1.1Dmm/Chd7tm1.1Dmm Tg(rx3-icre)1Mjam/0 involves: 129S6/SvEvTac	abnormal eye development	J:231044
	abnormal optic cup morphology	J:231044
	absent optic cup	J:231044
	coloboma	J:231044
	small lens	J:231044
Chd7tm1.2Dmm/Chd7tm1.2Dmm involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * FVB/N	abnormal semicircular canal morphology	J:164582
	circling	J:164582
	head bobbing	J:164582
Chd7tm2a(EUCOMM)Wtsi/Chd7+ 129S5;B6N-Chd7tm2a(EUCOMM)Wtsi/Wtsi	abnormal behavior	J:175295
	decreased body length	J:165965
	decreased body weight	J:165965
	decreased lumbar vertebrae number	J:175295
	hyperactivity	J:175295
Chd7tm2a(EUCOMM)Wtsi/Chd7+ involves: 129S5/SvEvBrd * C57BL/6N	abnormal circulating enzyme level	J:330596
	abnormal circulating lipoprotein level	J:330596
	abnormal corpus callosum morphology	J:330596
	abnormal hippocampus morphology	J:330596
	abnormal pupil morphology	J:330596
	abnormal response to stress-induced hyperthermia	J:330596
	abnormal retrosplenial granular cortex morphology	J:330596
	normal behavior/neurological phenotype	J:330596
	cataract	J:330596
	decreased body length	J:330596
	decreased body weight	J:330596
	decreased bone mineral content	J:330596
	decreased brain internal capsule size	J:330596
	decreased circulating alanine transaminase level	J:330596
	decreased circulating total protein level	J:330596
	decreased grip strength	J:330596
	decreased hematocrit	J:330596
	decreased hemoglobin content	J:330596
	decreased lean body mass	J:330596
	decreased leukocyte cell number	J:330596
	decreased monocyte cell number	J:330596
	decreased red blood cell distribution width	J:330596
	increased blood uric acid level	J:330596
	increased circulating alkaline phosphatase level	J:330596
	increased habenula size	J:330596
	increased mammillothalamic tract size	J:330596
	increased NK T cell number	J:330596
Chd7tm2a(EUCOMM)Wtsi/Chd7+ involves: 129S6/SvEvTac * C57BL/6N	circling	J:207089
	head bobbing	J:207089
Chd7tm2a(EUCOMM)Wtsi/Chd7tm2a(EUCOMM)Wtsi involves: 129S5/SvEvBrd * C57BL/6N	embryonic lethality during organogenesis, incomplete penetrance	J:330596
Chd7tm2a(EUCOMM)Wtsi/Chd7tm2a(EUCOMM)Wtsi involves: 129S6/SvEvTac * C57BL/6N	abnormal epigenetic regulation of gene expression	J:207089
	atrioventricular cushion hypoplasia	J:207089
	normal cardiovascular system phenotype	J:207089
	decreased fetal cardiomyocyte proliferation	J:207089
	embryonic growth arrest	J:207089
	embryonic lethality during organogenesis, complete penetrance	J:207089
	increased cardiomyocyte apoptosis	J:207089
	thin myocardium	J:207089
Chd7tm2a(EUCOMM)Wtsi/Chd7tm2a(EUCOMM)Wtsi Mesp1tm2(cre)Ysa/Mesp1+ involves: C57BL/6J * C57BL/6N * C57BL/6NCrlj * CBA/JNCrlj	abnormal atrioventricular cushion morphology	J:225736
	abnormal cardiac outflow tract development	J:225736
	abnormal coronary vein morphology	J:225736
	abnormal fetal cardiomyocyte physiology	J:225736
	abnormal heart development	J:225736
	abnormal innervation	J:225736
	abnormal myocardial trabeculae morphology	J:225736
	abnormal myocardium compact layer morphology	J:225736
	abnormal truncus arteriosus septation	J:225736
	abnormal vein morphology	J:225736
	aortopulmonary window	J:225736
	atrioventricular septal defect	J:225736
	normal cardiovascular system phenotype	J:225736
	common atrioventricular valve	J:225736
	congestive heart failure	J:225736
	double inlet heart left ventricle	J:225736
	double outlet right ventricle	J:225736
	edema	J:225736
	hemorrhage	J:225736
	interrupted aortic arch, type b	J:225736
	lethality throughout fetal growth and development, incomplete penetrance	J:225736
	perinatal lethality, complete penetrance	J:225736
	thin ventricle myocardium compact layer	J:225736
	thin ventricular wall	J:225736
Chd7tm2a(EUCOMM)Wtsi/Chd7tm2a(EUCOMM)Wtsi Tg(Tek-cre)1Ywa/0 involves: C57BL/6 * C57BL/6J * C57BL/6N * SJL	abnormal myocardium compact layer morphology	J:225736
	atrial septal defect	J:225736
	atrioventricular septal defect	J:225736
	normal cardiovascular system phenotype	J:225736
	edema	J:225736
	interrupted aortic arch, type b	J:225736
	preweaning lethality, incomplete penetrance	J:225736
	ventricular septal defect	J:225736
Chd7tm2c(EUCOMM)Wtsi/Chd7+ Tg(Atoh1-cre)1Bfri/0 involves: C57BL/6 * C57BL/6J * C57BL/6N * CBA	cochlear inner hair cell degeneration	J:314588
	cochlear outer hair cell degeneration	J:314588
	increased or absent threshold for auditory brainstem response	J:314588
Chd7tm2c(EUCOMM)Wtsi/Chd7+ Tg(Neurod1-cre)RZ24Gsat/0 involves: C57BL/6J * C57BL/6N * FVB/NTac	abnormal vestibulocochlear ganglion morphology	J:314588
	increased or absent threshold for auditory brainstem response	J:314588
	neuron degeneration	J:314588
Chd7tm2c(EUCOMM)Wtsi/Chd7tm2c(EUCOMM)Wtsi Ptf1atm1.1(cre)Cvw/Ptf1a+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6N	normal nervous system phenotype	J:243947
Chd7tm2c(EUCOMM)Wtsi/Chd7tm2c(EUCOMM)Wtsi Slc1a3tm1(cre/ERT2)Mgoe/Slc1a3+ involves: 129S2/SvPas * C57BL/6 * C57BL/6N * SJL	abnormal neuron number	J:222062
	abnormal neuronal stem cell morphology	J:222062
	decreased neuron number	J:222062
	decreased neuronal precursor cell number	J:222062
	increased neuron apoptosis	J:222062
	increased neuron number	J:222062
	increased neuronal precursor cell number	J:222062
	increased neuronal stem cell self-renewal	J:222062
Chd7tm2c(EUCOMM)Wtsi/Chd7tm2c(EUCOMM)Wtsi Tg(Atoh1-cre)1Bfri/0 involves: C57BL/6 * C57BL/6J * C57BL/6N * CBA	abnormal cerebellar foliation	J:242933
	abnormal cerebellar hemisphere morphology	J:242933
	abnormal cerebellum vermis lobule morphology	J:242933
	abnormal Purkinje cell morphology	J:242933
	normal behavior/neurological phenotype	J:242933
	behavioral developmental delay	J:242933
	cerebellum hypoplasia	J:242933
	cerebellum vermis hypoplasia	J:242933
	cochlear inner hair cell degeneration	J:314588
	cochlear outer hair cell degeneration	J:314588
	decreased cerebellar granule cell precursor proliferation	J:242933
	decreased Purkinje cell number	J:242933
	impaired coordination	J:242933
	impaired righting response	J:242933
	increased cellular sensitivity to oxidative stress	J:314588
	increased neuron apoptosis	J:242933
	increased or absent threshold for auditory brainstem response	J:314588
Chd7tm2c(EUCOMM)Wtsi/Chd7tm2c(EUCOMM)Wtsi Tg(Atoh1-cre)1Bfri/0 involves: C57BL/6 * C57BL/6N * CBA	abnormal cerebellar foliation	J:243947
	abnormal cerebellum morphology	J:243947
	abnormal Purkinje cell morphology	J:243947
	cerebellum hypoplasia	J:243947
	decreased cerebellar granule cell number	J:243947
	increased neuron apoptosis	J:243947
	premature neuronal precursor differentiation	J:243947
Chd7tm2c(EUCOMM)Wtsi/Chd7tm2c(EUCOMM)Wtsi Tg(Atoh1-cre/Esr1*)14Fsh/0 involves: C57BL/6N	normal hearing/vestibular/ear phenotype	J:314588
Chd7tm2c(EUCOMM)Wtsi/Chd7tm2c(EUCOMM)Wtsi Tg(Gdf9-icre)5092Coo/0 involves: C57BL/6 * C57BL/6J * C57BL/6N	decreased ovary weight	J:324165
	decreased primary ovarian follicle number	J:324165
	decreased primordial ovarian follicle number	J:324165
	decreased secondary ovarian follicle number	J:324165
	decreased tertiary ovarian follicle number	J:324165
	impaired ovarian folliculogenesis	J:324165
	increased atretic ovarian follicle number	J:324165
	increased granulosa cell apoptosis	J:324165
	reduced female fertility	J:324165
	small ovary	J:324165
Chd7tm2c(EUCOMM)Wtsi/Chd7tm2c(EUCOMM)Wtsi Tg(Nes-cre)1Kln/0 involves: C57BL/6 * C57BL/6J * C57BL/6N * SJL	abnormal cerebellar foliation	J:242933
	abnormal cerebellum fissure morphology	J:242933
	abnormal cerebellum vermis lobule IV morphology	J:242933
	abnormal cerebellum vermis lobule IX morphology	J:242933
	abnormal cerebellum vermis lobule morphology	J:242933
	abnormal cerebellum vermis lobule V morphology	J:242933
	cerebellum hypoplasia	J:242933
	cerebellum vermis hypoplasia	J:242933
	decreased body size	J:242933
	decreased brain size	J:242933
	ectopic cerebellar granule cells	J:242933
	postnatal lethality, incomplete penetrance	J:242933
	small cerebellum	J:242933
Chd7tm2c(EUCOMM)Wtsi/Chd7tm2c(EUCOMM)Wtsi Tg(Nes-cre)1Kln/0 involves: C57BL/6 * C57BL/6N * SJL	cerebellum hypoplasia	J:243947
	perinatal lethality, incomplete penetrance	J:243947
Chd7tm2c(EUCOMM)Wtsi/Chd7tm2c(EUCOMM)Wtsi Tg(Neurod1-cre)RZ24Gsat/0 involves: C57BL/6J * C57BL/6N * FVB/NTac	abnormal vestibulocochlear ganglion morphology	J:314588
	increased or absent threshold for auditory brainstem response	J:314588
	neuron degeneration	J:314588
Chd7Todo/Chd7+ involves: BALB/cAnNCrl * C3H/HeN	abnormal lateral semicircular canal morphology	J:75619
	abnormal posterior semicircular canal morphology	J:75619
	circling	J:63816
	decreased body size	J:75619
	head tossing	J:75619
Chd7Trooper/Chd7+ BALB/c-Chd7Trooper	abnormal lateral semicircular canal morphology	J:262283
	abnormal semicircular canal morphology	J:262283
	abnormal stapes footplate morphology	J:262283
	blepharitis	J:262283
	circling	J:262283
	conjunctivitis	J:262283
	decreased body weight	J:262283
	decreased posterior semicircular canal size	J:262283
	decreased superior semicircular canal size	J:262283
	head bobbing	J:262283
	head tilt	J:262283
	increased or absent threshold for auditory brainstem response	J:262283
	small stapes	J:262283
Chd7Trooper/Chd7Trooper BALB/c-Chd7Trooper	lethality, complete penetrance	J:262283
Chd7Whi/Chd7+ B6.C3Fe-Chd7Whi	abnormal lateral semicircular canal morphology	J:154590
	abnormal posterior semicircular canal morphology	J:154590
	absent lateral semicircular canal	J:154590
Chd7Whi/Chd7+ C3HeB/FeJ-Chd7Whi	abnormal circulating lipid level	J:330596
	abnormal circulating lipoprotein level	J:330596
	abnormal circulating mineral level	J:330596
	abnormal circulating protein level	J:330596
	abnormal cochlear hair cell morphology	J:99481
	abnormal corpus callosum morphology	J:330596
	abnormal glucose tolerance	J:330596
	abnormal hippocampus morphology	J:330596
	abnormal neurohypophysis median eminence morphology	J:161880
	abnormal olfactory bulb morphology	J:161880
	abnormal response to stress-induced hyperthermia	J:330596
	abnormal retrosplenial granular cortex morphology	J:330596
	abnormal round window morphology	J:99481
	abnormal stapes morphology	J:99481
	abnormal superior semicircular canal morphology	J:99481
	abnormal uterine horn morphology	J:161880
	abnormal uterus morphology	J:161880
	absent lateral semicircular canal	J:99481
	circling	J:99481
	decreased body fat mass	J:330596
	decreased body length	J:330596
	decreased body weight	J:161880, J:330596
	decreased circulating aspartate transaminase level	J:330596
	decreased circulating calcium level	J:330596
	decreased circulating cholesterol level	J:330596
	decreased circulating free fatty acids level	J:330596
	decreased circulating glycerol level	J:330596
	decreased circulating insulin level	J:330596
	decreased circulating magnesium level	J:330596
	decreased circulating potassium level	J:330596
	decreased circulating serum albumin level	J:330596
	decreased circulating triglyceride level	J:330596
	decreased grip strength	J:330596
	decreased hematocrit	J:330596
	decreased lateral semicircular canal size	J:99481
	decreased lean body mass	J:330596
	decreased monocyte cell number	J:330596
	decreased neuron number	J:161880
	decreased percent body fat/body weight	J:330596
	decreased testis weight	J:161880
	delayed fertility	J:161880
	enlarged third ventricle	J:330596
	head bobbing	J:99481, J:330596
	normal hearing/vestibular/ear phenotype	J:99481
	hyperactivity	J:99481
	impaired olfaction	J:161880
	increased blood urea nitrogen level	J:330596
	increased carbon dioxide production	J:330596
	increased cochlear inner hair cell number	J:99481
	increased cochlear outer hair cell number	J:99481
	increased locomotor activity	J:330596
	increased NK T cell number	J:330596
	increased oxygen consumption	J:330596
	increased thermal nociceptive threshold	J:330596
	olfactory bulb hypoplasia	J:161880
	small olfactory bulb	J:161880
	testis hypoplasia	J:161880
	trunk curl	J:330596
	normal vision/eye phenotype	J:330596
Chd7Whi/Chd7+ involves: C3HeB/FeJ	abnormal digit development	J:104123
	abnormal external female genitalia morphology	J:104123
	abnormal internal nares morphology	J:104123
	abnormal outer ear morphology	J:104123
	abnormal palatal shelf fusion at midline	J:104123
	abnormal secondary palate development	J:104123
	circling	J:104123
	cleft secondary palate	J:104123
	clitoris hypoplasia	J:104123
	decreased body weight	J:104123
	decreased palatal rugae number	J:104123
	decreased total body fat amount	J:104123
	dry eyes	J:104123
	edema	J:104123
	head shaking	J:104123
	hemorrhage	J:104123
	keratoconjunctivitis sicca	J:104123
	postnatal lethality	J:104123
	ventricular septal defect	J:104123