Chd7^Lda
Chemically induced Allele Detail

Summary

• Symbol: Chd7^Lda
• Name: chromodomain helicase DNA binding protein 7; leda
• MGI ID: MGI:2177299
• Gene: Chd7 Location: Chr4:8690406-8867659 bp, + strand Genetic Position: Chr4, 3.68 cM
• Alliance: Chd7^Lda page

Mutation origin

• Strain of Origin: BALB/cAnNCrl

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: A T3195A transition in exon 13 resulted in a Y1066X nonsense mutation. This mutation would lead to a protein lacking a large part of the SNF2 and all other more C-terminal located domains. (J:104123)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Chd7 Mutation: 136 strains or lines available

References

• Original: J:75619 Kiernan AE, et al., ENU mutagenesis reveals a highly mutable locus on mouse Chromosome 4 that affects ear morphogenesis. Mamm Genome. 2002 Mar;13(3):142-8
• All: 2 reference(s)