162 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Amhtm1Bhr/Amh+ Amhr2tm1Bhr/Amhr2tm1Bhr involves: 129S7/SvEvBrd * C57BL/6	increased testis tumor incidence	J:36027
	male pseudohermaphroditism	J:36027
	secondary sex reversal	J:36027
Amhtm1Bhr/Amhtm1Bhr Amhr2tm1Bhr/Amhr2tm1Bhr Not Specified	male infertility	J:36027
	male pseudohermaphroditism	J:36027
	normal reproductive system phenotype	J:36027
	secondary sex reversal	J:36027
Amhr2tm1Bhr/Amhr2tm1Bhr Inhatm1Bay/Inha+ involves: 129S7/SvEvBrd * C57BL/6	increased testis tumor incidence	J:36027
	male pseudohermaphroditism	J:36027
	secondary sex reversal	J:36027
Amhr2tm1Bhr/Amhr2tm1Bhr Inhatm1Bay/Inhatm1Bay involves: 129S7/SvEvBrd	dilated uterus	J:36027
	increased granulosa cell tumor incidence	J:36027
	increased Leydig cell tumor incidence	J:36027
	increased testis tumor incidence	J:36027
	increased tumor incidence	J:36027
	male pseudohermaphroditism	J:36027
	secondary sex reversal	J:36027
Amhr2tm3(cre)Bhr/Amhr2+ involves: 129S/SvEv * C57BL/6	early reproductive senescence	J:128934
	hemoperitoneum	J:128934
	increased ovarian carcinoma incidence	J:128934
	increased ovary tumor incidence	J:128934
	increased testis tumor incidence	J:128934
	male infertility	J:128934
Amhr2tm3(cre)Bhr/Amhr2+ KitW-v/KitW-v Trp53tm1Brn/Trp53tm1Brn involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J * FVB/N	increased granulosa cell tumor incidence	J:236161
	increased ovary adenoma incidence	J:236161
	increased ovary tumor incidence	J:236161
Amhr2tm3(cre)Bhr/Amhr2+ Nr5a1tm1Klp/Nr5a1tm2Klp involves: 129P2/OlaHsd * 129S7/SvEvBrd	abnormal endometrial gland development	J:145805
	abnormal endometrial gland morphology	J:145805
	abnormal estrous cycle	J:145805
	abnormal ovarian follicle number	J:91352, J:145805
	abnormal ovary physiology	J:145805
	abnormal ovulation	J:91352
	abnormal seminiferous tubule morphology	J:91352
	abnormal testis cord formation	J:91352
	abnormal testis development	J:91352
	abnormal uterus morphology	J:145805
	absent corpus luteum	J:91352, J:145805
	absent estrous cycle	J:145805
	absent sexual maturation	J:91352
	arrest of spermatogenesis	J:91352
	cryptorchism	J:91352
	decreased circulating estradiol level	J:145805
	decreased circulating testosterone level	J:91352
	decreased endometrial gland number	J:145805
	decreased granulosa cell proliferation	J:145805
	decreased ovary weight	J:145805
	decreased primary ovarian follicle number	J:145805
	decreased primordial ovarian follicle number	J:145805
	decreased secondary ovarian follicle number	J:145805
	decreased superovulation rate	J:145805
	decreased tertiary ovarian follicle number	J:145805
	decreased uterus weight	J:145805
	female infertility	J:91352, J:145805
	impaired ovarian folliculogenesis	J:145805
	increased circulating follicle stimulating hormone level	J:145805
	internal male genitalia hypoplasia	J:91352
	male infertility	J:91352
	ovarian follicular cyst	J:91352
	ovary hemorrhage	J:91352
	ovary hypoplasia	J:91352, J:145805
	prolonged estrous cycle	J:145805
	short estrus	J:145805
	small adrenal glands	J:91352
	small testis	J:91352
	testis hypoplasia	J:91352
	thin myometrium	J:145805
Amhr2tm3(cre)Bhr/Amhr2+ Wnt4tm1Amc/Wnt4tm1.1Bhr involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6J	normal reproductive system phenotype	J:171430
Amhr2tm3(cre)Bhr/Amhr2+ Fsttm1Zuk/Fsttm2Zuk involves: 129S/SvEv * C57BL/6J	abnormal ovary morphology	J:89081
	decreased circulating testosterone level	J:89081
	decreased corpora lutea number	J:89081
	decreased litter size	J:89081
	decreased superovulation rate	J:89081
	decreased tertiary ovarian follicle number	J:89081
	female infertility	J:89081
	normal homeostasis/metabolism phenotype	J:89081
	impaired fertilization	J:89081
	increased circulating follicle stimulating hormone level	J:89081
	increased circulating luteinizing hormone level	J:89081
	ovary cyst	J:89081
	ovary hemorrhage	J:89081
	reduced female fertility	J:89081
	normal reproductive system phenotype	J:89081
Amhr2tm3(cre)Bhr/Amhr2+ Smad3tm1Par/Smad3tm1Zuk involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6	normal reproductive system phenotype	J:142827
Amhr2tm3(cre)Bhr/Amhr2+ Smad2tm1Cxd/Smad2tm1.1Mwst involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6	normal reproductive system phenotype	J:142827
Amhr2tm3(cre)Bhr/Amhr2+ Smad2tm1Cxd/Smad2tm1.1Mwst Smad3tm1Par/Smad3tm1Zuk involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cumulus expansion	J:142827
	abnormal ovarian follicle morphology	J:142827
	decreased litter size	J:142827
	decreased oocyte number	J:142827
	decreased tertiary ovarian follicle number	J:142827
	increased atretic ovarian follicle number	J:142827
	increased circulating follicle stimulating hormone level	J:142827
	increased circulating luteinizing hormone level	J:142827
	premature ovarian failure	J:142827
	reduced female fertility	J:142827
Amhr2tm3(cre)Bhr/Amhr2+ Ctnnb1tm1Mmt/Ctnnb1+ involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6	increased granulosa cell tumor incidence	J:186144
	increased testis tumor incidence	J:186144
	male infertility	J:186144
	seminiferous tubule degeneration	J:186144
	testicular atrophy	J:186144
Amhr2tm3(cre)Bhr/Amhr2+ Ctnnb1tm1Mmt/Ctnnb1+ Ptentm1Hwu/Ptentm1Hwu involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ	anemia	J:142150
	decreased hematocrit	J:142150
	extramedullary hematopoiesis	J:142150
	increased granulosa cell tumor incidence	J:149060
	increased metastatic potential	J:142150, J:149060
	increased ovary tumor incidence	J:142150
	increased testis tumor incidence	J:149060
	premature death	J:142150
	pulmonary embolism	J:142150
	seminiferous tubule degeneration	J:149060
Amhr2tm3(cre)Bhr/Amhr2+ Ctnnb1tm1Mmt/Ctnnb1+ Ptentm1Hwu/Ptentm1Hwu involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6	increased granulosa cell tumor incidence	J:186144
	increased testis tumor incidence	J:186144
Amhr2tm3(cre)Bhr/Amhr2+ Inhbatm1Zuk/Inhbatm3Zuk involves: 129S7/SvEvBrd * C57BL/6J	decreased litter size	J:125354
	increased corpora lutea number	J:125354
	polyovular ovarian follicle	J:125354
	reduced female fertility	J:125354
Amhr2tm3(cre)Bhr/Amhr2+ Ctnnb1tm2Kem/Ctnnb1tm2.1Kem involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ	abnormal Mullerian duct morphology	J:171430
	abnormal sex determination	J:171430
	failure of Mullerian duct regression	J:171430
Amhr2tm3(cre)Bhr/Amhr2+ Smad1tm2Rob/Smad1tm2.1Rob Smad5tm1Huy/Smad5tm1Huy involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6	early reproductive senescence	J:128934
	hemoperitoneum	J:128934
	increased ovarian carcinoma incidence	J:128934
	increased ovary tumor incidence	J:128934
	increased testis tumor incidence	J:128934
	male infertility	J:128934
Amhr2tm3(cre)Bhr/Amhr2+ Smad1tm2Rob/Smad1tm2.1Rob Smad5tm1Huy/Smad5tm1Huy involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J	increased granulosa cell tumor incidence	J:157310
	premature death	J:157310
	suppressed circulating follicle stimulating hormone level	J:157310
Amhr2tm3(cre)Bhr/Amhr2+ Smad1tm2Rob/Smad1tm2Rob Smad5tm1Huy/Smad5tm1Huy involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J	increased granulosa cell tumor incidence	J:157310
	premature death	J:157310
	suppressed circulating follicle stimulating hormone level	J:157310
Amhr2tm3(cre)Bhr/Amhr2+ Smad1tm2Rob/Smad1tm2Rob Smad5tm1Huy/Smad5tm1Zuk involves: 129P2/OlaHsd * 129S/SvEv * 129S7/SvEvBrd * C57BL/6	early reproductive senescence	J:128934
	hemoperitoneum	J:128934
	increased ovarian carcinoma incidence	J:128934
	increased ovary tumor incidence	J:128934
	increased testis tumor incidence	J:128934
	male infertility	J:128934
Amhr2tm3(cre)Bhr/Amhr2+ Smad1tm2Rob/Smad1tm2Rob Smad5tm1Huy/Smad5tm1Zuk involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J	increased granulosa cell tumor incidence	J:157310
	premature death	J:157310
	suppressed circulating follicle stimulating hormone level	J:157310
Amhr2tm3(cre)Bhr/Amhr2+ Smad1tm2Rob/Smad1tm2Rob Smad5tm1Huy/Smad5tm1Zuk Smad9tm1Jfm/Smad9tm1Jfm involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6	early reproductive senescence	J:128934
	hemoperitoneum	J:128934
	increased ovarian carcinoma incidence	J:128934
	increased ovary tumor incidence	J:128934
Amhr2tm3(cre)Bhr/Amhr2+ Ptentm1Hwu/Ptentm1Hwu involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6	abnormal endometrium morphology	J:170203
	abnormal maternal decidual layer morphology	J:170203
	abnormal myometrium morphology	J:170203
	abnormal placenta labyrinth morphology	J:170203
	abnormal placenta vasculature	J:170203
	abnormal trophoblast layer morphology	J:170203
	decreased litter size	J:170203
	decreased uterine NK cell number	J:170203
	endometrium fibrosis	J:170203
	endometrium hyperplasia	J:170203
	reduced female fertility	J:170203
	normal reproductive system phenotype	J:187754
	uterus hyperplasia	J:170203
Amhr2tm3(cre)Bhr/Amhr2+ Bmpr1atm1Bhr/Bmpr1atm2.1Bhr involves: 129S7/SvEvBrd * C57BL/6	male pseudohermaphroditism	J:89999
	secondary sex reversal	J:89999
Amhr2tm3(cre)Bhr/Amhr2+ Stk11tm1Rdp/Stk11tm1Rdp involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6	abnormal seminiferous tubule epithelium morphology	J:187754
	abnormal seminiferous tubule morphology	J:187754
	abnormal Sertoli cell morphology	J:187754
	abnormal spermatogenesis	J:187754
	abnormal testis morphology	J:187754
	decreased male germ cell number	J:187754
	decreased testis weight	J:187754
	increased Sertoli cell proliferation	J:187754
	normal neoplasm	J:187754
	small testis	J:187754
Amhr2tm3(cre)Bhr/Amhr2+ Artm1Chc/Y involves: 129S/SvEv * C57BL/6	abnormal meiosis	J:118270
	abnormal seminiferous tubule morphology	J:118270
	arrest of male meiosis	J:118270
	arrest of spermatogenesis	J:118270
	azoospermia	J:118270
	decreased circulating testosterone level	J:118270
	male infertility	J:118270
	small seminiferous tubules	J:118270
	small testis	J:118270
Amhr2tm3(cre)Bhr/Amhr2+ Tsc1tm1Djk/Tsc1tm1Djk involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6	abnormal myometrium morphology	J:181774
	abnormal oocyte morphology	J:181774
	abnormal ovary physiology	J:181774
	abnormal oviduct morphology	J:181774
	abnormal preimplantation embryo development	J:181774
	abnormal seminiferous tubule epithelium morphology	J:187754
	abnormal seminiferous tubule morphology	J:187754
	abnormal Sertoli cell morphology	J:187754
	abnormal spermatogenesis	J:187754
	abnormal testis morphology	J:187754
	decreased male germ cell number	J:187754
	decreased primordial ovarian follicle number	J:181774
	decreased testis weight	J:187754
	dilated oviduct	J:181774
	endometrium hyperplasia	J:181774
	failure of embryo implantation	J:181774
	female infertility	J:181774
	impaired ovarian folliculogenesis	J:181774
	increased atretic ovarian follicle number	J:181774
	increased Sertoli cell proliferation	J:187754
	normal neoplasm	J:181774, J:187754
	oocyte degeneration	J:181774
	premature ovarian failure	J:181774
	prolonged estrus	J:181774
	normal reproductive system phenotype	J:181774
	short diestrus	J:181774
	small testis	J:187754
Amhr2tm3(cre)Bhr/Amhr2+ Trp53tm2Tyj/Trp53+ involves: 129S4/SvJae * 129S7/SvEvBrd	normal neoplasm	J:222579
Amhr2tm3(cre)Bhr/Amhr2+ Nr2f2tm2.1Tsa/Nr2f2tm2.1Tsa involves: 129S7/SvEvBrd	abnormal maternal decidual layer morphology	J:120852
	abnormal myometrium morphology	J:120852
	abnormal placenta development	J:120852
	abnormal placental labyrinth vasculature morphology	J:120852
	abnormal uterine environment	J:120852
	absent placental labyrinth	J:120852
	decreased spongiotrophoblast cell number	J:120852
	edema	J:120852
	embryonic lethality, incomplete penetrance	J:120852
	hemorrhage	J:120852
	impaired embryo implantation	J:120852
	increased miscarriage rate	J:120852
	increased trophoblast giant cell number	J:120852
	reduced female fertility	J:120852
	short uterine horn	J:120852
	vaginal hemorrhage	J:120852
Amhr2tm3(cre)Bhr/Amhr2+ Smad4tm1Rob/Smad4tm1.1Rob involves: 129S/SvEv * C57BL/6J	abnormal cumulus expansion	J:108954
	abnormal granulosa cell morphology	J:108954
	abnormal ovarian follicle morphology	J:108954
	abnormal ovarian folliculogenesis	J:108954
	abnormal secondary ovarian follicle morphology	J:108954
	absent cumulus expansion	J:108954
	decreased litter size	J:108954
	decreased oocyte number	J:108954
	decreased ovulation rate	J:108954
	decreased tertiary ovarian follicle number	J:108954
	increased circulating progesterone level	J:108954
	increased secondary ovarian follicle number	J:108954
	infertility	J:108954
Amhr2tm3(cre)Bhr/Amhr2+ Tsc2tm1.1Mjg/Tsc2tm1.1Mjg involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6	abnormal seminiferous tubule epithelium morphology	J:187754
	abnormal seminiferous tubule morphology	J:187754
	abnormal Sertoli cell morphology	J:187754
	abnormal spermatogenesis	J:187754
	abnormal testis morphology	J:187754
	decreased male germ cell number	J:187754
	decreased testis weight	J:187754
	increased Sertoli cell proliferation	J:187754
	normal neoplasm	J:187754
	small testis	J:187754
Amhr2tm3(cre)Bhr/Amhr2+ Ptprvtm1Kry/Ptprvtm1Kry involves: 129S/SvEv	normal reproductive system phenotype	J:170888
Amhr2tm3(cre)Bhr/Amhr2+ Wnt4tm1.1Boer/Wnt4tm1.2Boer involves: 129S1/Sv * 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ	abnormal kidney development	J:162337
	abnormal ovary development	J:162337
	decreased litter size	J:162337
	decreased mature ovarian follicle number	J:162337
	decreased ovary weight	J:162337
	decreased renal glomerulus number	J:162337
	disheveled coat	J:162337
	postnatal growth retardation	J:162337
	premature death	J:162337
Ctnnb1tm1Mmt/Ctnnb1+ Krastm4Tyj/Kras+ Amhr2tm3(cre)Bhr/Amhr2+ involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6	increased granulosa cell tumor incidence	J:186144
	increased testis tumor incidence	J:186144
	seminiferous tubule degeneration	J:186144
Dicer1tm1Bdh/Dicer1tm1Bdh Amhr2tm3(cre)Bhr/Amhr2+ involves: 129	abnormal oviduct morphology	J:142113
	abnormal oviduct transport	J:142113
	abnormal pregnancy	J:142113
	abnormal uterus morphology	J:142113
	decreased circulating progesterone level	J:142113
	decreased endometrial gland number	J:142113
	decreased ovary weight	J:142113
	decreased ovulation rate	J:142113
	decreased superovulation rate	J:142113
	decreased uterus weight	J:142113
	failure of embryo implantation	J:142113
	female infertility	J:142113
	normal homeostasis/metabolism phenotype	J:142113
	normal reproductive system phenotype	J:142113
	short oviduct	J:142113
	short uterine horn	J:142113
	small uterus	J:142113
	thin myometrium	J:142113
Dicer1tm1Tara/Dicer1tm1Tara Amhr2tm3(cre)Bhr/Amhr2+ involves: 129P2/OlaHsd * 129S7/SvEvBrd	normal neoplasm	J:222579
Dicer1tm1Tara/Dicer1tm1Tara Ptentm1Hwu/Ptentm1Hwu Amhr2tm3(cre)Bhr/Amhr2+ involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd	abnormal oviduct morphology	J:182161
	ascites	J:182161
	increased carcinoma incidence	J:182161
	increased metastatic potential	J:182161
	increased ovarian carcinoma incidence	J:182161
	premature death	J:182161
Dicer1tm1Tara/Dicer1tm1Tara Ptentm1Hwu/Ptentm1Hwu Trp53tm2Tyj/Trp53+ Amhr2tm3(cre)Bhr/Amhr2+ involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd	ascites	J:222579
	increased carcinoma incidence	J:222579
	increased metastatic potential	J:222579
	increased ovarian carcinoma incidence	J:222579
	premature death	J:222579
Dicer1tm1Tara/Dicer1tm1Tara Trp53tm2Tyj/Trp53+ Amhr2tm3(cre)Bhr/Amhr2+ involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd	normal neoplasm	J:222579
Foxo1tm1Rdp/Foxo1tm1.1Rdp Foxo3tm1Rdp/Foxo3tm1.1Rdp Amhr2tm3(cre)Bhr/Amhr2+ involves: 129S6/SvEvTac * 129S7/SvEvBrd	abnormal circulating hormone level	J:232961
	abnormal ovarian follicle morphology	J:232961
	decreased circulating luteinizing hormone level	J:232961
	increased circulating estradiol level	J:232961
	increased granulosa cell tumor incidence	J:232961
	ovary cyst	J:232961
	suppressed circulating follicle stimulating hormone level	J:232961
Gata4tm1.1Sad/Gata4tm1.1Sad Amhr2tm3(cre)Bhr/Amhr2+ involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6J	abnormal circulating hormone level	J:173711
	abnormal ovary physiology	J:173711
	abnormal seminiferous tubule epithelium morphology	J:169018
	abnormal Sertoli cell barrier function	J:169018
	abnormal Sertoli cell morphology	J:169018
	abnormal spermatid morphology	J:169018
	abnormal spermatogenesis	J:169018
	asthenozoospermia	J:169018
	decreased litter size	J:173711
	decreased male germ cell number	J:169018
	decreased sperm progressive motility	J:169018
	decreased superovulation rate	J:173711
	decreased testis weight	J:169018
	failure of superovulation	J:173711
	female infertility	J:173711
	normal homeostasis/metabolism phenotype	J:169018
	increased male germ cell apoptosis	J:169018
	multinucleated giant male germ cells	J:169018
	oligozoospermia	J:169018
	ovarian follicular cyst	J:173711
	ovary cyst	J:173711
	reduced female fertility	J:173711
	reduced male fertility	J:169018
	normal reproductive system phenotype	J:169018, J:173711
	seminiferous tubule degeneration	J:169018
	small ovary	J:173711
	small testis	J:169018
	testicular atrophy	J:169018
Inhbatm1Zuk/Inhbatm3Zuk Inhbbtm1Jae/Inhbbtm1Jae Amhr2tm3(cre)Bhr/Amhr2+ involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J	abnormal ovarian follicle morphology	J:125354
	abnormal tertiary ovarian follicle morphology	J:125354
	absent oocytes	J:125354
	female infertility	J:125354
	increased corpora lutea number	J:125354
	increased follicle stimulating hormone level	J:125354
	increased ovary weight	J:125354
	ovarian follicular cyst	J:125354
Kat8tm1Thl/Kat8tm1Thl Amhr2tm3(cre)Bhr/Amhr2+ involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6	normal reproductive system phenotype	J:242000
Kmt2btm1Afst/Kmt2btm1.1Afst Amhr2tm3(cre)Bhr/Amhr2+ involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6	abnormal DNA methylation	J:166778
	abnormal ovarian follicle number	J:166778
	decreased primary ovarian follicle number	J:166778
	decreased primordial ovarian follicle number	J:166778
	decreased secondary ovarian follicle number	J:166778
	increased atretic ovarian follicle number	J:166778
	increased circulating follicle stimulating hormone level	J:166778
	reduced female fertility	J:166778
Ptentm1Hwu/Ptentm1Hwu Amhr2tm3(cre)Bhr/Amhr2+ involves: 129S4/SvJae * 129S7/SvEvBrd	abnormal pregnancy	J:142150
	decreased litter size	J:142150
	increased granulosa cell tumor incidence	J:142150, J:222579
	increased metastatic potential	J:142150
	normal reproductive system phenotype	J:142150
Ptentm1Hwu/Ptentm1Hwu Trp53tm2Tyj/Trp53+ Amhr2tm3(cre)Bhr/Amhr2+ involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd	ascites	J:222579
	increased granulosa cell tumor incidence	J:222579
	increased metastatic potential	J:222579
	increased ovarian carcinoma incidence	J:222579
	premature death	J:222579
Tspotm1.1Wbd/Tspotm1.1Wbd Amhr2tm3(cre)Bhr/Amhr2+ involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6	normal reproductive system phenotype	J:207708