Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Casp1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CASP1
- Mouse genes Casp1
- Rat genes Casp1
- Zfish genes caspa
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Casp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050700	CARD domain binding	CASP1	IPI	UniProtKB:Q9Y2G2	Human	PMID:11821383
Molecular Function	GO:0050700	CARD domain binding	CASP1	IPI	UniProtKB:Q5EG05	Human	PMID:16920334
Molecular Function	GO:0140608	cysteine-type endopeptidase activator activity	CASP1	IDA		Human	PMID:32109412
Molecular Function	GO:0140608	cysteine-type endopeptidase activator activity	Casp1	IDA		Mouse	PMID:32109412
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	CASP1	IDA		Human	PMID:11821383
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	CASP1	IDA		Human	PMID:15326478
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	CASP1	IDA		Human	PMID:1574116
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	CASP1	IGI	UniProtKB:P10749,UniProtKB:Q9NPP4	Human	PMID:15882992
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	CASP1	IDA		Human	PMID:16920334
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	CASP1	IDA		Human	PMID:22464733
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	CASP1	IDA		Human	PMID:2787508
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	CASP1	IDA		Human	PMID:32109412
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	CASP1	IDA		Human	PMID:32553275
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	Casp1	IDA		Mouse	MGI:MGI:7327232\|PMID:18667412
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	Casp1	IDA		Mouse	MGI:MGI:6716955\|PMID:21147462
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	Casp1	IDA		Mouse	PMID:35705808
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	Casp1	IDA		Mouse	PMID:32109412
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	Casp1	IDA		Mouse	PMID:23395675
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	caspa	IDA		Zfish	PMID:12464617
Molecular Function	GO:0004175	endopeptidase activity	CASP1	IDA		Human	PMID:24548080
Molecular Function	GO:0004175	endopeptidase activity	caspa	IDA		Zfish	PMID:30150286
Molecular Function	GO:0042802	identical protein binding	CASP1	IMP		Human	PMID:11432859
Molecular Function	GO:0042802	identical protein binding	CASP1	IPI	UniProtKB:P29466	Human	PMID:24630722
Molecular Function	GO:0042802	identical protein binding	CASP1	IPI	UniProtKB:P29466	Human	PMID:27043298
Molecular Function	GO:0019900	kinase binding	CASP1	IPI	UniProtKB:O43353	Human	PMID:11432859
Molecular Function	GO:0019900	kinase binding	CASP1	IPI	UniProtKB:O43353	Human	PMID:11536016
Molecular Function	GO:0019900	kinase binding	CASP1	IPI	UniProtKB:O43353	Human	PMID:15383541
Molecular Function	GO:0140677	molecular function activator activity	Casp1	IDA		Mouse	PMID:32109412
Molecular Function	GO:0008233	peptidase activity	Casp1	IDA		Mouse	PMID:18490713
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:Q9NPP4	Human	PMID:11374873
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:Q9NPP4	Human	PMID:11390368
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:Q5EG05	Human	PMID:11432859
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:P57730	Human	PMID:11536016
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:Q5EG05	Human	PMID:11536016
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:P10636	Human	PMID:12888622
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:Q9Y2G2	Human	PMID:15030775
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:Q9C000	Human	PMID:15107016
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:Q9HC29	Human	PMID:15107016
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:Q9NPP4	Human	PMID:15107016
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:Q5XLA6	Human	PMID:15383541
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:Q8WX94	Human	PMID:15817483
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:Q9NPP4	Human	PMID:15882992
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:O95361	Human	PMID:16575408
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:O15553	Human	PMID:16785446
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:O15553-2	Human	PMID:16785446
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:P58753-2	Human	PMID:17360653
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:Q9C000	Human	PMID:17418785
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:Q9NPP4	Human	PMID:17418785
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:P01583	Human	PMID:18329368
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:P09038	Human	PMID:18329368
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:Q9C000	Human	PMID:18511561
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:Q9HC29	Human	PMID:18511561
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:Q9ULZ3	Human	PMID:24630722
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:Q08AM6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:Q9ULZ3	Human	PMID:25605870
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:P57730	Human	PMID:27043298
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:Q5XLA6	Human	PMID:27043298
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:Q08AM6	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:P30740	Human	PMID:30692621
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:Q9ULZ3	Human	PMID:31421660
Molecular Function	GO:0005515	protein binding	CASP1	IPI	UniProtKB:P57764	Human	PMID:34296442
Molecular Function	GO:0005515	protein binding	Casp1	IPI	UniProtKB:P18011	Mouse	MGI:MGI:3687416\|PMID:8670890
Molecular Function	GO:0005515	protein binding	Casp1	IPI	UniProtKB:Q9EPB4	Mouse	MGI:MGI:5432942\|PMID:22801494
Molecular Function	GO:0005515	protein binding	Casp1	IPI	UniProtKB:Q5SV42\|UniProtKB:Q8VHP7\|UniProtKB:Q9D154	Mouse	MGI:MGI:6294164\|PMID:30692621
Molecular Function	GO:0005515	protein binding	Casp1	IPI	UniProtKB:Q56134	Mouse	MGI:MGI:3687689\|PMID:10051653
Molecular Function	GO:0005515	protein binding	Casp1	IPI	UniProtKB:Q9EPB4	Mouse	MGI:MGI:5915552\|PMID:25605870
Molecular Function	GO:0005515	protein binding	Casp1	IPI	UniProtKB:Q3UP24	Mouse	MGI:MGI:5444805\|PMID:22885697
Molecular Function	GO:0005515	protein binding	Casp1	IPI	UniProtKB:Q3UP24	Mouse	MGI:MGI:5914198\|PMID:26449474
Molecular Function	GO:0005515	protein binding	Casp1	IPI	PR:Q9EPB4	Mouse	PMID:15190255
Molecular Function	GO:0005515	protein binding	Casp1	IPI	PR:P28033	Mouse	PMID:11684016
Molecular Function	GO:0005515	protein binding	Casp1	IPI	RGD:628637	Rat	PMID:18367607\|RGD:2315889
Molecular Function	GO:0005515	protein binding	Casp1	IPI	RGD:735204	Rat	PMID:19416975\|RGD:5491011
Molecular Function	GO:0005515	protein binding	caspa	IPI	ZFIN:ZDB-GENE-020812-1	Zfish	PMID:29791979
Molecular Function	GO:0032090	Pyrin domain binding	caspa	IPI	ZFIN:ZDB-GENE-000511-2	Zfish	PMID:12464617
Molecular Function	GO:0097110	scaffold protein binding	Casp1	IPI	RGD:628637	Rat	PMID:19416975\|RGD:5491011
Cellular Component	GO:0097169	AIM2 inflammasome complex	CASP1	IPI		Human	PMID:24630722
Cellular Component	GO:0097169	AIM2 inflammasome complex	CASP1	IDA		Human	PMID:19158676
Cellular Component	GO:0061702	canonical inflammasome complex	CASP1	IPI		Human	PMID:16037825
Cellular Component	GO:0061702	canonical inflammasome complex	caspa	IPI	ZFIN:ZDB-GENE-000511-2,ZFIN:ZDB-GENE-120709-59	Zfish	PMID:30150286
Cellular Component	GO:0005737	cytoplasm	CASP1	IDA		Human	PMID:20197547
Cellular Component	GO:0005737	cytoplasm	Casp1	IDA		Mouse	PMID:21147462
Cellular Component	GO:0005737	cytoplasm	Casp1	IDA		Rat	PMID:18367607\|RGD:2315889
Cellular Component	GO:0005737	cytoplasm	Casp1	IDA		Rat	PMID:19401709\|RGD:5491174
Cellular Component	GO:0005829	cytosol	CASP1	IDA		Human	PMID:20197547
Cellular Component	GO:0005829	cytosol	Casp1	IDA		Mouse	PMID:35705808
Cellular Component	GO:0005576	extracellular region	Casp1	IDA		Mouse	PMID:15190255
Cellular Component	GO:0072557	IPAF inflammasome complex	Casp1	IDA		Mouse	MGI:MGI:5289703\|PMID:21874021
Cellular Component	GO:0043005	neuron projection	Casp1	IDA		Rat	PMID:19401709\|RGD:5491174
Cellular Component	GO:0072558	NLRP1 inflammasome complex	CASP1	IPI		Human	PMID:17349957
Cellular Component	GO:0072558	NLRP1 inflammasome complex	CASP1	IDA		Human	PMID:12191486
Cellular Component	GO:0072558	NLRP1 inflammasome complex	caspa	IPI		Zfish	PMID:30150286\|ZFIN:ZDB-PUB-180829-2
Cellular Component	GO:0072558	NLRP1 inflammasome complex	caspa	IDA		Zfish	PMID:30150286\|ZFIN:ZDB-PUB-180829-2
Cellular Component	GO:0072559	NLRP3 inflammasome complex	CASP1	IPI		Human	PMID:29255148
Cellular Component	GO:0072559	NLRP3 inflammasome complex	CASP1	IDA		Human	PMID:15030775
Cellular Component	GO:0005634	nucleus	Casp1	IDA		Rat	PMID:18367607\|RGD:2315889
Cellular Component	GO:0097179	protease inhibitor complex	CASP1	IMP		Human	PMID:11432859
Cellular Component	GO:0032991	protein-containing complex	CASP1	IMP		Human	PMID:11536016
Cellular Component	GO:0032991	protein-containing complex	CASP1	IMP		Human	PMID:11821383
Cellular Component	GO:0032991	protein-containing complex	CASP1	IMP		Human	PMID:15383541
Cellular Component	GO:0032991	protein-containing complex	CASP1	IDA		Human	PMID:16920334
Cellular Component	GO:0032991	protein-containing complex	Casp1	IDA		Rat	PMID:19416975\|RGD:5491011
Biological Process	GO:0140970	AIM2 inflammasome complex assembly	CASP1	IDA		Human	PMID:19158675
Biological Process	GO:0140970	AIM2 inflammasome complex assembly	Casp1	IDA		Mouse	PMID:23567559
Biological Process	GO:0140970	AIM2 inflammasome complex assembly	Casp1	IDA		Mouse	PMID:27846608
Biological Process	GO:0140970	AIM2 inflammasome complex assembly	Casp1	IDA		Mouse	PMID:32350463
Biological Process	GO:0006915	apoptotic process	Casp1	IEP		Rat	PMID:11404793\|RGD:631309
Biological Process	GO:0071222	cellular response to lipopolysaccharide	CASP1	IMP		Human	PMID:11536016
Biological Process	GO:0071222	cellular response to lipopolysaccharide	CASP1	IDA		Human	PMID:22464733
Biological Process	GO:0071260	cellular response to mechanical stimulus	CASP1	IEP		Human	PMID:19593445
Biological Process	GO:0071310	cellular response to organic substance	CASP1	IDA		Human	PMID:19158679
Biological Process	GO:0071346	cellular response to type II interferon	CASP1	IMP		Human	PMID:11536016
Biological Process	GO:0140447	cytokine precursor processing	CASP1	IGI	UniProtKB:P10749,UniProtKB:Q9NPP4	Human	PMID:15882992
Biological Process	GO:0042742	defense response to bacterium	Casp1	IDA		Mouse	PMID:35705808
Biological Process	GO:0050829	defense response to Gram-negative bacterium	Casp1	IMP		Mouse	MGI:MGI:6391726\|PMID:29887864
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	caspa	IMP	ZFIN:ZDB-MRPHLNO-120808-1	Zfish	PMID:12464617
Biological Process	GO:0045087	innate immune response	caspa	IGI	ZFIN:ZDB-MRPHLNO-180823-3	Zfish	PMID:29123523
Biological Process	GO:0032610	interleukin-1 alpha production	Casp1	IMP		Mouse	PMID:18490713
Biological Process	GO:0032611	interleukin-1 beta production	Casp1	IGI	MGI:MGI:2686159	Mouse	PMID:19158679
Biological Process	GO:0032611	interleukin-1 beta production	Casp1	IMP		Mouse	PMID:18490713
Biological Process	GO:0032611	interleukin-1 beta production	Casp1	IGI	MGI:MGI:1931465	Mouse	PMID:19158679
Biological Process	GO:0032611	interleukin-1 beta production	Casp1	IGI	MGI:MGI:96543	Mouse	PMID:19158679
Biological Process	GO:0030324	lung development	Casp1	IEP		Rat	PMID:12396474\|RGD:5130192
Biological Process	GO:0010934	macrophage cytokine production	Casp1	IMP		Mouse	PMID:18490713
Biological Process	GO:0060081	membrane hyperpolarization	Casp1	IMP		Mouse	PMID:23028046
Biological Process	GO:0007613	memory	Casp1	IMP		Rat	PMID:16197515\|RGD:2315922
Biological Process	GO:0001774	microglial cell activation	Casp1	IMP		Rat	PMID:15149850\|RGD:2315925
Biological Process	GO:0007494	midgut development	Casp1	IEP		Rat	PMID:12396474\|RGD:5130192
Biological Process	GO:0051882	mitochondrial depolarization	Casp1	IMP		Mouse	PMID:23028046
Biological Process	GO:0007520	myoblast fusion	Casp1	IMP		Rat	PMID:12832042\|RGD:1298731
Biological Process	GO:0002221	pattern recognition receptor signaling pathway	Casp1	IDA		Mouse	MGI:MGI:3806421\|PMID:18725521
Biological Process	GO:0043065	positive regulation of apoptotic process	Casp1	IMP		Rat	PMID:15663890\|RGD:2315924
Biological Process	GO:0043065	positive regulation of apoptotic process	caspa	IDA		Zfish	PMID:12464617
Biological Process	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	Casp1	IMP		Rat	PMID:16455762\|RGD:2315921
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	CASP1	IMP		Human	PMID:16920334
Biological Process	GO:0001819	positive regulation of cytokine production	Casp1	IDA		Mouse	MGI:MGI:6716955\|PMID:21147462
Biological Process	GO:0001819	positive regulation of cytokine production	Casp1	IMP		Rat	PMID:17384935\|RGD:2315892
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	CASP1	IEP		Human	PMID:12761501
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	CASP1	IMP		Human	PMID:15383541
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Casp1	IDA		Mouse	MGI:MGI:3773087\|PMID:16585594
Biological Process	GO:0050729	positive regulation of inflammatory response	CASP1	IDA		Human	PMID:12191486
Biological Process	GO:0050729	positive regulation of inflammatory response	CASP1	IDA		Human	PMID:15326478
Biological Process	GO:0050729	positive regulation of inflammatory response	CASP1	IDA		Human	PMID:32109412
Biological Process	GO:0050729	positive regulation of inflammatory response	Casp1	IDA		Mouse	MGI:MGI:6141801\|PMID:27270401
Biological Process	GO:0050729	positive regulation of inflammatory response	Casp1	IDA		Mouse	MGI:MGI:3806421\|PMID:18725521
Biological Process	GO:0050729	positive regulation of inflammatory response	Casp1	IDA		Mouse	PMID:32109412
Biological Process	GO:0032730	positive regulation of interleukin-1 alpha production	Casp1	IMP		Mouse	PMID:18490713
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	CASP1	IDA		Human	PMID:11432859
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	CASP1	IMP		Human	PMID:11536016
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	CASP1	IDA		Human	PMID:11821383
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	CASP1	IDA		Human	PMID:15326478
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	CASP1	IDA		Human	PMID:16037825
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	CASP1	IMP		Human	PMID:22267217
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	CASP1	IDA		Human	PMID:24630722
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	CASP1	IDA		Human	PMID:7642516
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	Casp1	IDA		Mouse	MGI:MGI:6141801\|PMID:27270401
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	Casp1	IDA		Mouse	MGI:MGI:6112461\|PMID:29255148
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	Casp1	IDA		Mouse	MGI:MGI:3806421\|PMID:18725521
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	Casp1	IDA		Mouse	MGI:MGI:6716955\|PMID:21147462
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	Casp1	IMP		Mouse	PMID:18490713
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	Casp1	IMP		Rat	PMID:16942597\|RGD:2315918
Biological Process	GO:0032741	positive regulation of interleukin-18 production	CASP1	IDA		Human	PMID:15326478
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	Casp1	IMP		Mouse	PMID:18490713
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Casp1	IDA		Mouse	MGI:MGI:3029677\|PMID:14663141
Biological Process	GO:0010954	positive regulation of protein processing	caspa	IMP		Zfish	PMID:31852739
Biological Process	GO:0010954	positive regulation of protein processing	caspa	IDA		Zfish	PMID:31852739
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	Casp1	IDA		Mouse	MGI:MGI:3029677\|PMID:14663141
Biological Process	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway	CASP1	IMP		Human	PMID:16920334
Biological Process	GO:0097300	programmed necrotic cell death	Casp1	IDA		Mouse	PMID:16429160
Biological Process	GO:0016540	protein autoprocessing	CASP1	IDA		Human	PMID:11821383
Biological Process	GO:0016540	protein autoprocessing	CASP1	IDA		Human	PMID:32109412
Biological Process	GO:0016540	protein autoprocessing	Casp1	IDA		Mouse	MGI:MGI:6716955\|PMID:21147462
Biological Process	GO:0051604	protein maturation	CASP1	IDA		Human	PMID:15326478
Biological Process	GO:0051604	protein maturation	CASP1	IDA		Human	PMID:22464733
Biological Process	GO:0051604	protein maturation	CASP1	IDA		Human	PMID:32109412
Biological Process	GO:0051604	protein maturation	Casp1	IDA		Mouse	PMID:35705808
Biological Process	GO:0051604	protein maturation	Casp1	IDA		Mouse	PMID:32109412
Biological Process	GO:0016485	protein processing	Casp1	IMP		Mouse	PMID:16301672
Biological Process	GO:0016485	protein processing	Casp1	IMP	MGI:MGI:1927822	Mouse	PMID:14663141
Biological Process	GO:0016485	protein processing	Casp1	IDA		Mouse	PMID:15190255
Biological Process	GO:0016485	protein processing	Casp1	IDA		Mouse	PMID:11016935
Biological Process	GO:0006508	proteolysis	CASP1	IDA		Human	PMID:12888622
Biological Process	GO:0006508	proteolysis	CASP1	IDA		Human	PMID:24548080
Biological Process	GO:0070269	pyroptosis	CASP1	IDA		Human	PMID:32109412
Biological Process	GO:0070269	pyroptosis	CASP1	IDA		Human	PMID:32553275
Biological Process	GO:0070269	pyroptosis	Casp1	IDA		Mouse	MGI:MGI:6716955\|PMID:21147462
Biological Process	GO:0070269	pyroptosis	Casp1	IDA		Mouse	MGI:MGI:5751630\|PMID:26611636
Biological Process	GO:0070269	pyroptosis	Casp1	IMP	MGI:MGI:2158744	Mouse	PMID:22002608
Biological Process	GO:0070269	pyroptosis	caspa	IGI	ZFIN:ZDB-GENO-210602-8	Zfish	PMID:32332700
Biological Process	GO:0010506	regulation of autophagy	Casp1	IMP	MGI:MGI:2158744	Mouse	PMID:24581500
Biological Process	GO:0050727	regulation of inflammatory response	CASP1	IDA		Human	PMID:32109412
Biological Process	GO:0050727	regulation of inflammatory response	CASP1	IDA		Human	PMID:32553275
Biological Process	GO:0050727	regulation of inflammatory response	Casp1	IMP	MGI:MGI:2158744	Mouse	PMID:22297845
Biological Process	GO:0033198	response to ATP	Casp1	IMP		Mouse	PMID:18490713
Biological Process	GO:0009617	response to bacterium	Casp1	IMP	MGI:MGI:2158744	Mouse	PMID:24581500
Biological Process	GO:0001666	response to hypoxia	Casp1	IMP	MGI:MGI:1927822	Mouse	PMID:14663141
Biological Process	GO:0001666	response to hypoxia	Casp1	IDA		Rat	PMID:12829320\|RGD:2315926
Biological Process	GO:0032496	response to lipopolysaccharide	Casp1	IDA		Mouse	PMID:16301672
Biological Process	GO:0032496	response to lipopolysaccharide	Casp1	IMP		Rat	PMID:17384935\|RGD:2315892
Biological Process	GO:0014070	response to organic cyclic compound	Casp1	IDA		Rat	PMID:17561093\|RGD:2315891
Biological Process	GO:0009636	response to toxic substance	Casp1	IEP		Rat	PMID:20638366\|RGD:5130198
Biological Process	GO:0009410	response to xenobiotic stimulus	Casp1	IDA		Rat	PMID:16165281\|RGD:2315923
Biological Process	GO:0097264	self proteolysis	caspa	IDA		Zfish	PMID:31852739
Biological Process	GO:0140448	signaling receptor ligand precursor processing	CASP1	IGI	UniProtKB:P10749,UniProtKB:Q9NPP4	Human	PMID:15882992
Biological Process	GO:1901998	toxin transport	Casp1	IMP		Mouse	PMID:23716698

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.