| GO term: | proteolysis |
| Synonym: | ATP-dependent proteolysis |
| Synonym: | peptidolysis |
| GO id: | GO:0006508 |
| Definition: | The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. |
| Comments | This term was intentionally placed under 'protein metabolic process ; GO:0019538' rather than 'protein catabolic process ; GO:0030163' to cover all processes centered on breaking peptide bonds, including those involved in protein maturation. |
| Number of paths to term: | 2 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
biological_processmetabolic processorganic substance metabolic processmacromolecule metabolic processprotein metabolic processacyl-carrier-protein biosynthetic process +amyloid fibril formationamyloid precursor protein metabolic process +cellular protein metabolic process +cytokine metabolic process +glutaredoxin biosynthetic processglycoprotein metabolic process +hemoglobin metabolic process +insulin metabolic process +lipoprotein metabolic process +metabolism by organism of protein in other organism involved in symbiotic interaction +multicellular organismal protein metabolic process +negative regulation of protein metabolic process +positive regulation of protein metabolic process +protein activation cascade +protein catabolic process +protein maturation +protein modification process +proteolysis [GO:0006508] (969 genes, 1273 annotations)membrane protein proteolysis +negative regulation of proteolysis +positive regulation of proteolysis +proteolysis in other organism +proteolysis involved in cellular protein catabolic process +regulation of proteolysis +self proteolysisregulation of protein metabolic process +thioredoxin biosynthetic processbiological_processmetabolic processprimary metabolic processprotein metabolic processacyl-carrier-protein biosynthetic process +amyloid fibril formationamyloid precursor protein metabolic process +cellular protein metabolic process +cytokine metabolic process +glutaredoxin biosynthetic processglycoprotein metabolic process +hemoglobin metabolic process +insulin metabolic process +lipoprotein metabolic process +metabolism by organism of protein in other organism involved in symbiotic interaction +multicellular organismal protein metabolic process +negative regulation of protein metabolic process +positive regulation of protein metabolic process +protein activation cascade +protein catabolic process +protein maturation +protein modification process +proteolysis [GO:0006508] (969 genes, 1273 annotations)membrane protein proteolysis +negative regulation of proteolysis +positive regulation of proteolysis +proteolysis in other organism +proteolysis involved in cellular protein catabolic process +regulation of proteolysis +self proteolysisregulation of protein metabolic process +thioredoxin biosynthetic processMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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