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Gene Ontology Browser
Term Detail
GO term:peptidase activity
Synonym: hydrolase, acting on peptide bonds
Synonym: peptide hydrolase activity
Synonym: protease activity
Synonym: proteinase activity
GO id:GO:0008233
Definition:Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-ahydrolase activity
                                is-abeta-alanyl-dopamine hydrolase activity
                                is-abeta-alanyl-histamine hydrolase activity
                                is-acoenzyme F390-A hydrolase activity
                                is-acoenzyme F390-G hydrolase activity
                                is-acytosine C-5 DNA demethylase activity
                                is-adeacetylase activity +
                                is-aGPI-anchor transamidase activity
                                is-ahydrolase activity, acting on acid anhydrides +
                                is-ahydrolase activity, acting on acid carbon-carbon bonds +
                                is-ahydrolase activity, acting on acid carbon-phosphorus bonds +
                                is-ahydrolase activity, acting on acid halide bonds +
                                is-ahydrolase activity, acting on acid phosphorus-nitrogen bonds +
                                is-ahydrolase activity, acting on acid sulfur-nitrogen bonds +
                                is-ahydrolase activity, acting on acid sulfur-sulfur bonds +
                                is-ahydrolase activity, acting on carbon-nitrogen (but not peptide) bonds +
                                is-ahydrolase activity, acting on carbon-sulfur bonds +
                                is-ahydrolase activity, acting on ester bonds +
                                is-ahydrolase activity, acting on ether bonds +
                                is-ahydrolase activity, acting on glycosyl bonds +
                                is-apalmitoyl hydrolase activity +
                                is-apeptidase activity [GO:0008233] (629 genes, 1875 annotations)
                                        is-aisopeptidase activity +
                                        is-aoligopeptidase activity
                                        is-apeptidase activity, acting on D-amino acid peptides
                                        is-apeptidase activity, acting on L-amino acid peptides +
                                is-aserine hydrolase activity +
                                is-aubiquitinyl hydrolase activity +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory