| GO term: | cysteine-type endopeptidase activity |
| Synonym: | caspase activity |
| Synonym: | lysosomal cysteine-type endopeptidase |
| Synonym: | metacaspase activity |
| Synonym: | thiol endopeptidase activity |
| GO id: | GO:0004197 |
| Definition: | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. |
| Number of paths to term: | 2 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functioncatalytic activityhydrolase activitypeptidase activitypeptidase activity, acting on L-amino acid peptidescysteine-type peptidase activitycysteine-type endopeptidase activity [GO:0004197] (50 genes, 61 annotations)calcium-dependent cysteine-type endopeptidase activitycysteine-type endopeptidase activity involved in apoptotic process +cysteine-type endopeptidase activity involved in plant-type hypersensitive responsesmall conjugating protein-specific endopeptidase activity +cysteine-type exopeptidase activity +small conjugating protein-specific protease activity +molecular_functioncatalytic activityhydrolase activitypeptidase activitypeptidase activity, acting on L-amino acid peptidesendopeptidase activityaspartic-type endopeptidase activity +cysteine-type endopeptidase activity [GO:0004197] (50 genes, 61 annotations)calcium-dependent cysteine-type endopeptidase activitycysteine-type endopeptidase activity involved in apoptotic process +cysteine-type endopeptidase activity involved in plant-type hypersensitive responsesmall conjugating protein-specific endopeptidase activity +glutamic-type endopeptidase activitymetalloendopeptidase activityserine-type endopeptidase activitythreonine-type endopeptidase activityMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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