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Gene Ontology Browser
Term Detail
GO term:protein processing
Synonym: peptidolysis during protein maturation
Synonym: protein maturation by peptide bond cleavage
Synonym: protein maturation by peptide bond hydrolysis
Synonym: protein maturation by proteolysis
GO id:GO:0016485
Definition:Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
Number of paths to term: 3

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-agene expression
                                                part-ofprotein maturation
                                                        is-aCAAX-box protein maturation +
                                                        is-aepidermal growth factor receptor ligand maturation +
                                                        negatively-regulatesnegative regulation of protein maturation +
                                                        is-apatched ligand maturation
                                                        is-apeptide pheromone maturation +
                                                        positively-regulatespositive regulation of protein maturation +
                                                        is-aprotein maturation by iron-sulfur cluster transfer
                                                        is-aprotein maturation by protein folding
                                                        is-aprotein processing [GO:0016485] (501 genes, 737 annotations)
                                                                is-aactivation of plasma proteins involved in acute inflammatory response +
                                                                is-aCAAX-box protein processing
                                                                is-adibasic protein processing +
                                                                is-amitochondrial protein processing +
                                                                negatively-regulatesnegative regulation of protein processing +
                                                                is-aNotch receptor processing, ligand-independent
                                                                is-apeptide bond cleavage involved in epidermal growth factor receptor ligand maturation
                                                                is-apeptide hormone processing +
                                                                positively-regulatespositive regulation of protein processing +
                                                                is-aprotein autoprocessing
                                                                is-aprotein initiator methionine removal involved in protein maturation
                                                                is-aprotein processing in phagocytic vesicle
                                                                is-aprotein splicing +
                                                                regulatesregulation of protein processing +
                                                                is-asignal peptide processing +
                                                                is-asterol regulatory element binding protein cleavage +
                                                                is-avacuolar protein processing +
                                                                is-aviral protein processing
                                                                is-azymogen activation +
                                                        regulatesregulation of protein maturation +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                is-aprotein maturation
                                                        is-aCAAX-box protein maturation +
                                                        is-aepidermal growth factor receptor ligand maturation +
                                                        negatively-regulatesnegative regulation of protein maturation +
                                                        is-apatched ligand maturation
                                                        is-apeptide pheromone maturation +
                                                        positively-regulatespositive regulation of protein maturation +
                                                        is-aprotein maturation by iron-sulfur cluster transfer
                                                        is-aprotein maturation by protein folding
                                                        is-aprotein processing [GO:0016485] (501 genes, 737 annotations)
                                                                is-aactivation of plasma proteins involved in acute inflammatory response +
                                                                is-aCAAX-box protein processing
                                                                is-adibasic protein processing +
                                                                is-amitochondrial protein processing +
                                                                negatively-regulatesnegative regulation of protein processing +
                                                                is-aNotch receptor processing, ligand-independent
                                                                is-apeptide bond cleavage involved in epidermal growth factor receptor ligand maturation
                                                                is-apeptide hormone processing +
                                                                positively-regulatespositive regulation of protein processing +
                                                                is-aprotein autoprocessing
                                                                is-aprotein initiator methionine removal involved in protein maturation
                                                                is-aprotein processing in phagocytic vesicle
                                                                is-aprotein splicing +
                                                                regulatesregulation of protein processing +
                                                                is-asignal peptide processing +
                                                                is-asterol regulatory element binding protein cleavage +
                                                                is-avacuolar protein processing +
                                                                is-aviral protein processing
                                                                is-azymogen activation +
                                                        regulatesregulation of protein maturation +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        is-aprotein maturation
                                                is-aCAAX-box protein maturation +
                                                is-aepidermal growth factor receptor ligand maturation +
                                                negatively-regulatesnegative regulation of protein maturation +
                                                is-apatched ligand maturation
                                                is-apeptide pheromone maturation +
                                                positively-regulatespositive regulation of protein maturation +
                                                is-aprotein maturation by iron-sulfur cluster transfer
                                                is-aprotein maturation by protein folding
                                                is-aprotein processing [GO:0016485] (501 genes, 737 annotations)
                                                        is-aactivation of plasma proteins involved in acute inflammatory response +
                                                        is-aCAAX-box protein processing
                                                        is-adibasic protein processing +
                                                        is-amitochondrial protein processing +
                                                        negatively-regulatesnegative regulation of protein processing +
                                                        is-aNotch receptor processing, ligand-independent
                                                        is-apeptide bond cleavage involved in epidermal growth factor receptor ligand maturation
                                                        is-apeptide hormone processing +
                                                        positively-regulatespositive regulation of protein processing +
                                                        is-aprotein autoprocessing
                                                        is-aprotein initiator methionine removal involved in protein maturation
                                                        is-aprotein processing in phagocytic vesicle
                                                        is-aprotein splicing +
                                                        regulatesregulation of protein processing +
                                                        is-asignal peptide processing +
                                                        is-asterol regulatory element binding protein cleavage +
                                                        is-avacuolar protein processing +
                                                        is-aviral protein processing
                                                        is-azymogen activation +
                                                regulatesregulation of protein maturation +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory