| GO term: | pattern recognition receptor signaling pathway |
| Synonym: | PAMP receptor signaling pathway |
| Synonym: | pathogen receptor signaling pathway |
| Synonym: | pathogen receptor signalling pathway |
| Synonym: | PRR signaling pathway |
| GO id: | GO:0002221 |
| Definition: | Any series of molecular signals generated as a consequence of binding to a cell surface or intracellular pattern recognition receptor (PRR). Such receptors bind for molecular patterns based on a repeating or polymeric structures, like those of polysaccharides or peptidoglycans, which are sometimes associated with potential pathogens. |
| Number of paths to term: | 124 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
biological_processbiological regulationregulation of biological processpositive regulation of biological processpositive regulation of immune system processpositive regulation of immune responseactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processpositive regulation of biological processpositive regulation of immune system processpositive regulation of immune responseactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processpositive regulation of biological processpositive regulation of immune system processpositive regulation of immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processpositive regulation of biological processpositive regulation of response to stimuluspositive regulation of defense responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processpositive regulation of biological processpositive regulation of response to stimuluspositive regulation of immune responseactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processpositive regulation of biological processpositive regulation of response to stimuluspositive regulation of immune responseactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processpositive regulation of biological processpositive regulation of response to stimuluspositive regulation of immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionimmune response-regulating signaling pathwayimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processregulation of immune system processpositive regulation of immune system processpositive regulation of immune responseactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processregulation of immune system processpositive regulation of immune system processpositive regulation of immune responseactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processregulation of immune system processpositive regulation of immune system processpositive regulation of immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processregulation of immune system processregulation of immune responseimmune response-regulating signaling pathwayimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processregulation of immune system processregulation of immune responsepositive regulation of immune responseactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processregulation of immune system processregulation of immune responsepositive regulation of immune responseactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processregulation of immune system processregulation of immune responsepositive regulation of immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processregulation of immune system processregulation of immune responseregulation of innate immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processregulation of response to stimuluspositive regulation of response to stimuluspositive regulation of defense responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processregulation of response to stimuluspositive regulation of response to stimuluspositive regulation of immune responseactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processregulation of response to stimuluspositive regulation of response to stimuluspositive regulation of immune responseactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processregulation of response to stimuluspositive regulation of response to stimuluspositive regulation of immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processregulation of response to stimulusregulation of immune responseimmune response-regulating signaling pathwayimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processregulation of response to stimulusregulation of immune responsepositive regulation of immune responseactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processregulation of response to stimulusregulation of immune responsepositive regulation of immune responseactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processregulation of response to stimulusregulation of immune responsepositive regulation of immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processregulation of response to stimulusregulation of immune responseregulation of innate immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processregulation of response to stimulusregulation of response to stressregulation of defense responsepositive regulation of defense responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processbiological regulationregulation of biological processregulation of response to stimulusregulation of response to stressregulation of defense responseregulation of innate immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processcellular processregulation of cellular processsignal transductionimmune response-regulating signaling pathwayimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionimmune response-regulating signaling pathwayimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionimmune response-regulating signaling pathwayimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processimmune responseinnate immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processimmune responseinnate immune responseregulation of innate immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processimmune responsepositive regulation of immune responseactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processimmune responsepositive regulation of immune responseactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processimmune responsepositive regulation of immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processimmune responseregulation of immune responseimmune response-regulating signaling pathwayimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processimmune responseregulation of immune responsepositive regulation of immune responseactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processimmune responseregulation of immune responsepositive regulation of immune responseactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processimmune responseregulation of immune responsepositive regulation of immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processimmune responseregulation of immune responseregulation of innate immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processpositive regulation of immune system processpositive regulation of immune responseactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processpositive regulation of immune system processpositive regulation of immune responseactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processpositive regulation of immune system processpositive regulation of immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processregulation of immune system processpositive regulation of immune system processpositive regulation of immune responseactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processregulation of immune system processpositive regulation of immune system processpositive regulation of immune responseactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processregulation of immune system processpositive regulation of immune system processpositive regulation of immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processregulation of immune system processregulation of immune responseimmune response-regulating signaling pathwayimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processregulation of immune system processregulation of immune responsepositive regulation of immune responseactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processregulation of immune system processregulation of immune responsepositive regulation of immune responseactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processregulation of immune system processregulation of immune responsepositive regulation of immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processimmune system processregulation of immune system processregulation of immune responseregulation of innate immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processpositive regulation of biological processpositive regulation of immune system processpositive regulation of immune responseactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processpositive regulation of biological processpositive regulation of immune system processpositive regulation of immune responseactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processpositive regulation of biological processpositive regulation of immune system processpositive regulation of immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processpositive regulation of biological processpositive regulation of response to stimuluspositive regulation of defense responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processpositive regulation of biological processpositive regulation of response to stimuluspositive regulation of immune responseactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processpositive regulation of biological processpositive regulation of response to stimuluspositive regulation of immune responseactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processpositive regulation of biological processpositive regulation of response to stimuluspositive regulation of immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processpositive regulation of biological processpositive regulation of immune system processpositive regulation of immune responseactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processpositive regulation of biological processpositive regulation of immune system processpositive regulation of immune responseactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processpositive regulation of biological processpositive regulation of immune system processpositive regulation of immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processpositive regulation of biological processpositive regulation of response to stimuluspositive regulation of defense responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processpositive regulation of biological processpositive regulation of response to stimuluspositive regulation of immune responseactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processpositive regulation of biological processpositive regulation of response to stimuluspositive regulation of immune responseactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processpositive regulation of biological processpositive regulation of response to stimuluspositive regulation of immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processregulation of cellular processsignal transductionimmune response-regulating signaling pathwayimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processregulation of immune system processpositive regulation of immune system processpositive regulation of immune responseactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processregulation of immune system processpositive regulation of immune system processpositive regulation of immune responseactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processregulation of immune system processpositive regulation of immune system processpositive regulation of immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processregulation of immune system processregulation of immune responseimmune response-regulating signaling pathwayimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processregulation of immune system processregulation of immune responsepositive regulation of immune responseactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processregulation of immune system processregulation of immune responsepositive regulation of immune responseactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processregulation of immune system processregulation of immune responsepositive regulation of immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processregulation of immune system processregulation of immune responseregulation of innate immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processregulation of response to stimuluspositive regulation of response to stimuluspositive regulation of defense responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processregulation of response to stimuluspositive regulation of response to stimuluspositive regulation of immune responseactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processregulation of response to stimuluspositive regulation of response to stimuluspositive regulation of immune responseactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processregulation of response to stimuluspositive regulation of response to stimuluspositive regulation of immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processregulation of response to stimulusregulation of immune responseimmune response-regulating signaling pathwayimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processregulation of response to stimulusregulation of immune responsepositive regulation of immune responseactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processregulation of response to stimulusregulation of immune responsepositive regulation of immune responseactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processregulation of response to stimulusregulation of immune responsepositive regulation of immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processregulation of response to stimulusregulation of immune responseregulation of innate immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processregulation of response to stimulusregulation of response to stressregulation of defense responsepositive regulation of defense responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processregulation of biological processregulation of response to stimulusregulation of response to stressregulation of defense responseregulation of innate immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processresponse to stimuluscellular response to stimulussignal transductionimmune response-regulating signaling pathwayimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processresponse to stimulusimmune responseinnate immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processresponse to stimulusimmune responseinnate immune responseregulation of innate immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processresponse to stimulusimmune responsepositive regulation of immune responseactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processresponse to stimulusimmune responsepositive regulation of immune responseactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processresponse to stimulusimmune responsepositive regulation of immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processresponse to stimulusimmune responseregulation of immune responseimmune response-regulating signaling pathwayimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processresponse to stimulusimmune responseregulation of immune responsepositive regulation of immune responseactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processresponse to stimulusimmune responseregulation of immune responsepositive regulation of immune responseactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processresponse to stimulusimmune responseregulation of immune responsepositive regulation of immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processresponse to stimulusimmune responseregulation of immune responseregulation of innate immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processresponse to stimuluspositive regulation of response to stimuluspositive regulation of defense responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processresponse to stimuluspositive regulation of response to stimuluspositive regulation of immune responseactivation of immune responseactivation of innate immune responseinnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processresponse to stimuluspositive regulation of response to stimuluspositive regulation of immune responseactivation of immune responseimmune response-activating signal transductioninnate immune response-activating signal transductionactivation of MAPK activity involved in innate immune responseactivation of MAPKK activity involved in innate immune responseactivation of MAPKKK activity involved in innate immune responseinnate immune response activating cell surface receptor signaling pathway +MAPK import into nucleus involved in innate immune responsepattern recognition receptor signaling pathway [GO:0002221] (66 genes, 119 annotations)cell surface pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathway +intracellular vesicle pattern recognition receptor signaling pathwaytoll-like receptor signaling pathway +biological_processresponse to stimuluspositive regulation of response to stimuluspositive regulation of immune responsepositive regulation of innate immune responseactivation of innate immune responseinnate immune response-activating signal transduction
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