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Gene Ontology Browser
Term Detail
GO term:innate immune response
Synonym: innate immunity
Synonym: nonspecific immune response
GO id:GO:0045087
Definition:Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
CommentsThis term was improved by GO_REF:0000022. It was moved.
Number of paths to term: 3

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aimmune response
                                is-aadaptive immune response +
                                part-ofcell activation involved in immune response +
                                part-ofcytokine production involved in immune response +
                                is-ahumoral immune response +
                                is-aimmune response involved in response to exogenous dsRNA
                                is-aimmune response to tumor cell +
                                is-ainflammatory response to antigenic stimulus +
                                is-ainnate immune response [GO:0045087] (425 genes, 711 annotations)
                                        is-acomplement activation, alternative pathway +
                                        is-acomplement activation, lectin pathway +
                                        is-adefense response, incompatible interaction +
                                        is-ahemolymph coagulation
                                        is-ainduced systemic resistance +
                                        is-ainnate immune response in mucosa
                                        part-ofMAPK cascade involved in innate immune response +
                                        is-amelanization defense response +
                                        is-anatural killer cell mediated immunity +
                                        negatively-regulatesnegative regulation of innate immune response +
                                        is-aplant-type hypersensitive response +
                                        positively-regulatespositive regulation of innate immune response +
                                        regulatesregulation of innate immune response +
                                        part-ofresponse to interferon-gamma +
                                        part-ofresponse to type I interferon +
                                        part-ofresponse to type III interferon +
                                        is-avirus induced gene silencing +
                                part-ofleukocyte migration involved in immune response +
                                negatively-regulatesnegative regulation of immune response +
                                is-aorgan or tissue specific immune response +
                                positively-regulatespositive regulation of immune response +
                                regulatesregulation of immune response +
                                is-atype 2 immune response +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aimmune response
                                is-aadaptive immune response +
                                part-ofcell activation involved in immune response +
                                part-ofcytokine production involved in immune response +
                                is-ahumoral immune response +
                                is-aimmune response involved in response to exogenous dsRNA
                                is-aimmune response to tumor cell +
                                is-ainflammatory response to antigenic stimulus +
                                is-ainnate immune response [GO:0045087] (425 genes, 711 annotations)
                                        is-acomplement activation, alternative pathway +
                                        is-acomplement activation, lectin pathway +
                                        is-adefense response, incompatible interaction +
                                        is-ahemolymph coagulation
                                        is-ainduced systemic resistance +
                                        is-ainnate immune response in mucosa
                                        part-ofMAPK cascade involved in innate immune response +
                                        is-amelanization defense response +
                                        is-anatural killer cell mediated immunity +
                                        negatively-regulatesnegative regulation of innate immune response +
                                        is-aplant-type hypersensitive response +
                                        positively-regulatespositive regulation of innate immune response +
                                        regulatesregulation of innate immune response +
                                        part-ofresponse to interferon-gamma +
                                        part-ofresponse to type I interferon +
                                        part-ofresponse to type III interferon +
                                        is-avirus induced gene silencing +
                                part-ofleukocyte migration involved in immune response +
                                negatively-regulatesnegative regulation of immune response +
                                is-aorgan or tissue specific immune response +
                                positively-regulatespositive regulation of immune response +
                                regulatesregulation of immune response +
                                is-atype 2 immune response +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to stress
                                is-adefense response
                                        is-abehavioral defense response +
                                        is-acellular defense response +
                                        is-aclearance of foreign intracellular DNA +
                                        is-adefense response by callose deposition +
                                        part-ofdefense response by callose deposition in cell wall
                                        is-adefense response by cell wall thickening +
                                        is-adefense response to other organism +
                                        is-adefense response to tumor cell
                                        is-ainflammatory response +
                                        is-ainnate immune response [GO:0045087] (425 genes, 711 annotations)
                                                is-acomplement activation, alternative pathway +
                                                is-acomplement activation, lectin pathway +
                                                is-adefense response, incompatible interaction +
                                                is-ahemolymph coagulation
                                                is-ainduced systemic resistance +
                                                is-ainnate immune response in mucosa
                                                part-ofMAPK cascade involved in innate immune response +
                                                is-amelanization defense response +
                                                is-anatural killer cell mediated immunity +
                                                negatively-regulatesnegative regulation of innate immune response +
                                                is-aplant-type hypersensitive response +
                                                positively-regulatespositive regulation of innate immune response +
                                                regulatesregulation of innate immune response +
                                                part-ofresponse to interferon-gamma +
                                                part-ofresponse to type I interferon +
                                                part-ofresponse to type III interferon +
                                                is-avirus induced gene silencing +
                                        negatively-regulatesnegative regulation of defense response +
                                        positively-regulatespositive regulation of defense response +
                                        regulatesregulation of defense response +
                                        part-ofrespiratory burst involved in defense response +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory