| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | 17-beta hydroxysteroid dehydrogenase 3 deficiency | HSD17B3* | Hsd17b3* | 1 model | Alliance of Genome Resources | ||
| 46,XY sex reversal | DHH* | Dhh* | 1 model | Alliance of Genome Resources | |||
| androgen insensitivity syndrome | AR* | Ar* | 8 models | Alliance of Genome Resources | |||
| cryptorchidism | INSL3* | Insl3* | 5 models | Alliance of Genome Resources | |||
| hypogonadotropic hypogonadism 11 with or without anosmia | TACR3* | Tacr3* | 1 model | Alliance of Genome Resources | |||
| hypogonadotropic hypogonadism 12 with or without anosmia | GNRH1* | Gnrh1* | 1 model | Alliance of Genome Resources | |||
| hypogonadotropic hypogonadism 13 with or without anosmia | KISS1* | Kiss1* | 2 models | Alliance of Genome Resources | |||
| hypogonadotropic hypogonadism 7 with or without anosmia | GNRHR* | Gnrhr* | 1 model | Alliance of Genome Resources | |||
| hypogonadotropic hypogonadism 8 with or without anosmia | KISS1R* | Kiss1r* | 4 models | Alliance of Genome Resources | |||
| Kallmann syndrome | SOX10* | Sox10* | 1 model | Alliance of Genome Resources | |||
| ovarian cancer | CTNNB1* | Ctnnb1* | 6 models | Alliance of Genome Resources | |||
| persistent Mullerian duct syndrome | AMHR2* | Amhr2* | 1 model | Alliance of Genome Resources | |||
| primary ovarian insufficiency 12 | SYCE1* | Syce1* | 1 model | Alliance of Genome Resources | |||
| primary ovarian insufficiency 13 | MSH5* | Msh5* | 1 model | Alliance of Genome Resources | |||
| primary ovarian insufficiency 19 | HSF2BP* | Hsf2bp* | 1 model | Alliance of Genome Resources | |||
| | 46 XX gonadal dysgenesis | FANCL | Fancl* | 1 model | Alliance of Genome Resources | ||
| androgen insensitivity syndrome | FKBP4 | Fkbp4* | 2 models | Alliance of Genome Resources | |||
| dermoid cyst of ovary | FOXO3, FOXO3B | Foxo3* | 1 model | Alliance of Genome Resources | |||
| hyperandrogenism | Prl3c1* | 1 model | |||||
| hypogonadotropic hypogonadism | NR5A1 | Nr5a1* | 1 model | Alliance of Genome Resources | |||
| Kallmann syndrome | WDR11 | Wdr11* | 1 model | Alliance of Genome Resources | |||
| ovarian cancer | APC | Apc* | 2 models | Alliance of Genome Resources | |||
| ovarian disease | PATL2 | Patl2* | 1 model | Alliance of Genome Resources | |||
| ovarian hyperstimulation syndrome | NR1H3 | Nr1h3* | 1 model | Alliance of Genome Resources | |||
| polycystic ovary syndrome | AKT2 | Akt2* | 1 model | Alliance of Genome Resources | |||
| primary ovarian insufficiency | FANCF | Fancf* | 1 model | Alliance of Genome Resources | |||
| primary ovarian insufficiency | POLR3H | Polr3h* | 1 model | Alliance of Genome Resources | |||
| | 46 XX gonadal dysgenesis | ZSWIM7* | Zswim7 | Alliance of Genome Resources | |||
| 46 XX gonadal dysgenesis | SPIDR* | Spidr | Alliance of Genome Resources | ||||
| 46 XX gonadal dysgenesis | FSHR* | Fshr | Alliance of Genome Resources | ||||
| 46,XX sex reversal 1 | SRY* | Sry | Alliance of Genome Resources | ||||
| 46,XX sex reversal 4 | NR5A1* | Nr5a1 | Alliance of Genome Resources | ||||
| 46,XX sex reversal 5 | NR2F2* | Nr2f2 | Alliance of Genome Resources | ||||
| 46,XY sex reversal | SRY* | Sry | Alliance of Genome Resources | ||||
| 46,XY sex reversal | DHX37* | Dhx37 | Alliance of Genome Resources | ||||
| 46,XY sex reversal 1 | SRY* | Sry | Alliance of Genome Resources | ||||
| 46,XY sex reversal 2 | NR0B1* | Nr0b1 | Alliance of Genome Resources | ||||
| 46,XY sex reversal 3 | NR5A1* | Nr5a1 | Alliance of Genome Resources | ||||
| 46,XY sex reversal 5 | CBX2* | Cbx2 | Alliance of Genome Resources | ||||
| 46,XY sex reversal 6 | MAP3K1* | Map3k1 | Alliance of Genome Resources | ||||
| 46,XY sex reversal 7 | DHH* | Dhh | Alliance of Genome Resources | ||||
| 46,XY sex reversal 8 | AKR1C2*, AKR1C4*, AKR1C1, AKR1C3 | Akr1c6, Akr1c12, Akr1c13, Akr1c14, Akr1c18, Akr1c19, Akr1c20, Akr1c21, Akr1cl | Alliance of Genome Resources | ||||
| 46,XY sex reversal 9 | ZFPM2* | Zfpm2 | Alliance of Genome Resources | ||||
| cryptorchidism | RXFP2* | Rxfp2 | 2 models | Alliance of Genome Resources | |||
| cryptorchidism | AR* | Ar | 1 model | Alliance of Genome Resources | |||
| cryptorchidism | HOXD13* | Hoxd13 | Alliance of Genome Resources | ||||
| disorder of sexual development | HSD17B3* | Hsd17b3 | Alliance of Genome Resources | ||||
| disorder of sexual development | AMH* | Amh | Alliance of Genome Resources | ||||
| dysgerminoma | KIT* | Kit | Alliance of Genome Resources | ||||
| dysgerminoma | FGFR2* | Fgfr2 | Alliance of Genome Resources | ||||
| gonadal disease | LHCGR* | Lhcgr | Alliance of Genome Resources | ||||
| gonadal dysgenesis | TSPYL1*, TSPYL6 | Tspyl1 | Alliance of Genome Resources | ||||
| hyperandrogenism | IL6ST* | Il6st | Alliance of Genome Resources | ||||
| hypogonadism | PROP1* | Prop1 | Alliance of Genome Resources | ||||
| hypogonadism | KISS1R* | Kiss1r | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism | NDNF* | Ndnf | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism | TCF12* | Tcf12 | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism | NHLH2* | Nhlh2 | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism 10 with or without anosmia | TAC3* | Tac2 | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism 14 with or without anosmia | WDR11* | Wdr11 | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism 15 with or without anosmia | HS6ST1* | Hs6st1 | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism 16 with or without anosmia | SEMA3A* | Sema3a | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism 17 with or without anosmia | SPRY4* | Spry4 | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism 18 with or without anosmia | IL17RD* | Il17rd | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism 19 with or without anosmia | DUSP6* | Dusp6 | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism 1 with or without anosmia | ANOS1* | ||||||
| hypogonadotropic hypogonadism 20 with or without anosmia | FGF17* | Fgf17 | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism 21 with or without anosmia | FLRT3* | Flrt3 | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism 22 with or without anosmia | FEZF1* | Fezf1 | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism 23 with or without anosmia | LHB*, CGB1, CGB2, CGB3, CGB5, CGB7, CGB8 | Lhb | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism 24 without anosmia | FSHB* | Fshb | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism 2 with or without anosmia | FGFR1* | Fgfr1 | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism 3 with or without anosmia | PROKR2* | Prokr2 | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism 4 with or without anosmia | PROK2* | Prok2 | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism 5 with or without anosmia | CHD7* | Chd7 | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism 6 with or without anosmia | FGF8* | Fgf8 | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism 7 with or without anosmia | FGFR1* | Fgfr1 | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism 7 with or without anosmia | NSMF* | Nsmf | Alliance of Genome Resources | ||||
| hypogonadotropic hypogonadism 9 with or without anosmia | NSMF* | Nsmf | Alliance of Genome Resources | ||||
| Leydig cell hypoplasia | LHCGR* | Lhcgr | Alliance of Genome Resources | ||||
| methemoglobinemia and ambiguous genitalia | CYB5A* | Cyb5a | Alliance of Genome Resources | ||||
| Mullerian aplasia and hyperandrogenism | WNT4* | Wnt4 | Alliance of Genome Resources | ||||
| ovarian cancer | NOS3* | Nos3 | Alliance of Genome Resources | ||||
| ovarian cancer | AKT1* | Akt1 | Alliance of Genome Resources | ||||
| ovarian cancer | APEX1* | Apex1 | Alliance of Genome Resources | ||||
| ovarian cancer | APOB* | Apob | Alliance of Genome Resources | ||||
| ovarian cancer | AURKA* | Aurka | Alliance of Genome Resources | ||||
| ovarian cancer | BARD1* | Bard1 | Alliance of Genome Resources | ||||
| ovarian cancer | BRCA1* | Brca1 | 2 models | Alliance of Genome Resources | |||
| ovarian cancer | BRCA2* | Brca2 | 1 model | Alliance of Genome Resources | |||
| ovarian cancer | CAMK2N1* | Camk2n1 | Alliance of Genome Resources | ||||
| ovarian cancer | CCNG1* | Ccng1 | Alliance of Genome Resources | ||||
| ovarian cancer | CD59* | Cd59a, Cd59b | Alliance of Genome Resources | ||||
| ovarian cancer | CDH1* | Cdh1 | Alliance of Genome Resources | ||||
| ovarian cancer | CDH13* | Cdh13 | Alliance of Genome Resources | ||||
| ovarian cancer | CLDN4* | Cldn4, Cldn13 | Alliance of Genome Resources | ||||
| ovarian cancer | COMT* | Comt | Alliance of Genome Resources | ||||
| ovarian cancer | CYP19A1* | Cyp19a1 | Alliance of Genome Resources | ||||
| ovarian cancer | EEF1A2* | Eef1a2 | Alliance of Genome Resources | ||||
| ovarian cancer | ERBB2* | Erbb2 | Alliance of Genome Resources | ||||
| ovarian cancer | FANCA* | Fanca | Alliance of Genome Resources | ||||
| ovarian cancer | GHRH* | Ghrh | Alliance of Genome Resources | ||||
| ovarian cancer | GSTA1*, GSTA2, GSTA3, GSTA5 | Gsta1, Gsta2, Gsta3, Gsta5, Gsta13 | Alliance of Genome Resources | ||||
| ovarian cancer | GSTP1* | Gstp1, Gstp2, Gstp3, Gstp-ps | Alliance of Genome Resources | ||||
| ovarian cancer | HFE* | Hfe | Alliance of Genome Resources | ||||
| ovarian cancer | HMGA2* | Hmga2 | Alliance of Genome Resources | ||||
| ovarian cancer | ITGA8* | Itga8 | Alliance of Genome Resources | ||||
| ovarian cancer | JAK1* | Jak1 | Alliance of Genome Resources | ||||
| ovarian cancer | JUP* | Jup | Alliance of Genome Resources | ||||
| ovarian cancer | LEF1* | Lef1 | Alliance of Genome Resources | ||||
| ovarian cancer | MBL2* | Mbl2 | Alliance of Genome Resources | ||||
| ovarian cancer | MIR1271* | ||||||
| ovarian cancer | MMP1* | Mmp1a, Mmp1b | Alliance of Genome Resources | ||||
| ovarian cancer | MSLN* | Msln | Alliance of Genome Resources | ||||
| ovarian cancer | MUC16* | Muc16 | Alliance of Genome Resources | ||||
| ovarian cancer | MYO6* | Myo6 | Alliance of Genome Resources | ||||
| ovarian cancer | NBN* | Nbn | Alliance of Genome Resources | ||||
| ovarian cancer | NOD2* | Nod2 | Alliance of Genome Resources | ||||
| ovarian cancer | OGG1* | Ogg1 | Alliance of Genome Resources | ||||
| ovarian cancer | OIP5-AS1* | ||||||
| ovarian cancer | OPCML* | Opcml | Alliance of Genome Resources | ||||
| ovarian cancer | PIK3CA* | Pik3ca | 1 model | Alliance of Genome Resources | |||
| ovarian cancer | PMS2*, PMS2P1, PMS2P2, PMS2P6 | Pms2 | Alliance of Genome Resources | ||||
| ovarian cancer | POT1* | Pot1a, Pot1b | Alliance of Genome Resources | ||||
| ovarian cancer | PRKCA* | Prkca | Alliance of Genome Resources | ||||
| ovarian cancer | PRKN* | Prkn | Alliance of Genome Resources | ||||
| ovarian cancer | PTEN* | Pten | 8 models | Alliance of Genome Resources | |||
| ovarian cancer | RAD51* | Rad51 | Alliance of Genome Resources | ||||
| ovarian cancer | RASSF1* | Rassf1 | Alliance of Genome Resources | ||||
| ovarian cancer | RUNX3* | Runx3 | Alliance of Genome Resources | ||||
| ovarian cancer | SMAD2* | Smad2 | Alliance of Genome Resources | ||||
| ovarian cancer | SMAD4* | Smad4 | Alliance of Genome Resources | ||||
| ovarian cancer | SOD2* | Sod2 | Alliance of Genome Resources | ||||
| ovarian cancer | STAT3* | Stat3 | Alliance of Genome Resources | ||||
| ovarian cancer | TFRC* | Tfrc | Alliance of Genome Resources | ||||
| ovarian cancer | UGT1A1* | Ugt1a1 | Alliance of Genome Resources | ||||
| ovarian cancer | WRAP53* | Wrap53 | Alliance of Genome Resources | ||||
| ovarian carcinoma | SOCS2* | Socs2 | Alliance of Genome Resources | ||||
| ovarian carcinoma | SOCS1* | Socs1 | Alliance of Genome Resources | ||||
| ovarian carcinoma | CYTB* | mt-Cytb | Alliance of Genome Resources | ||||
| ovarian carcinoma | MMP13* | Mmp13 | Alliance of Genome Resources | ||||
| ovarian carcinoma | MIR23B* | Mir23b | Alliance of Genome Resources | ||||
| ovarian carcinoma | MAP2K6* | Map2k6 | Alliance of Genome Resources | ||||
| ovarian carcinoma | L1CAM* | L1cam | Alliance of Genome Resources | ||||
| ovarian carcinoma | CCNG1* | Ccng1 | Alliance of Genome Resources | ||||
| ovarian carcinoma | CCND1* | Ccnd1 | Alliance of Genome Resources | ||||
| ovarian carcinoma | CASP6* | Casp6 | Alliance of Genome Resources | ||||
| ovarian carcinoma | CAMK2N1* | Camk2n1 | Alliance of Genome Resources | ||||
| ovarian carcinoma | CABIN1* | Cabin1 | Alliance of Genome Resources | ||||
| ovarian carcinoma | AMH* | Amh | Alliance of Genome Resources | ||||
| ovarian carcinoma | AKT2* | Akt2 | Alliance of Genome Resources | ||||
| ovarian carcinoma | STK11* | Stk11 | Alliance of Genome Resources | ||||
| ovarian clear cell carcinoma | ARID1A* | Arid1a | Alliance of Genome Resources | ||||
| ovarian dysgenesis 1 | FSHR* | Fshr | Alliance of Genome Resources | ||||
| ovarian dysgenesis 2 | BMP15* | Bmp15 | Alliance of Genome Resources | ||||
| ovarian dysgenesis 3 | PSMC3IP* | Psmc3ip | Alliance of Genome Resources | ||||
| ovarian dysgenesis 4 | MCM9* | Mcm9 | Alliance of Genome Resources | ||||
| ovarian dysgenesis 5 | SOHLH1* | Sohlh1 | Alliance of Genome Resources | ||||
| ovarian dysgenesis 6 | NUP107* | Nup107 | Alliance of Genome Resources | ||||
| ovarian dysgenesis 7 | MRPS22* | Mrps22 | Alliance of Genome Resources | ||||
| ovarian dysgenesis 8 | ESR2* | Esr2 | Alliance of Genome Resources | ||||
| ovarian endometrial cancer | ARHGEF10L* | Arhgef10l | Alliance of Genome Resources | ||||
| ovarian hyperstimulation syndrome | FSHR* | Fshr | Alliance of Genome Resources | ||||
| ovarian hyperstimulation syndrome | SERPINF1* | Serpinf1 | Alliance of Genome Resources | ||||
| ovarian serous carcinoma | ARHGEF10L* | Arhgef10l | Alliance of Genome Resources | ||||
| ovarian serous carcinoma | MAP2K4* | Map2k4 | Alliance of Genome Resources | ||||
| ovary epithelial cancer | NME1* | Nme1 | Alliance of Genome Resources | ||||
| ovary epithelial cancer | H19* | ||||||
| ovary epithelial cancer | ERCC1* | Ercc1 | Alliance of Genome Resources | ||||
| ovary epithelial cancer | DAXX* | Daxx | Alliance of Genome Resources | ||||
| ovary epithelial cancer | CCR3* | Ccr3 | Alliance of Genome Resources | ||||
| ovary epithelial cancer | AKAP6* | Akap6 | Alliance of Genome Resources | ||||
| ovary epithelial cancer | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| ovary epithelial cancer | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| ovary epithelial cancer | ERCC2* | Ercc2 | Alliance of Genome Resources | ||||
| ovary epithelial cancer | TAB2* | Tab2 | Alliance of Genome Resources | ||||
| ovary epithelial cancer | KIF1B* | Kif1b | Alliance of Genome Resources | ||||
| ovary serous adenocarcinoma | TP53* | Trp53 | Alliance of Genome Resources | ||||
| partial androgen insensitivity syndrome | AR* | Ar | Alliance of Genome Resources | ||||
| persistent Mullerian duct syndrome | AMH* | Amh | Alliance of Genome Resources | ||||
| polycystic ovary syndrome | VDR* | Vdr | Alliance of Genome Resources | ||||
| polycystic ovary syndrome | FST* | Fst | Alliance of Genome Resources | ||||
| polycystic ovary syndrome | CYP19A1* | Cyp19a1 | Alliance of Genome Resources | ||||
| polycystic ovary syndrome | CYP1A1* | Cyp1a1 | Alliance of Genome Resources | ||||
| polycystic ovary syndrome | CAPN10* | Capn10 | Alliance of Genome Resources | ||||
| premature menopause | POLG* | Polg | Alliance of Genome Resources | ||||
| primary ovarian insufficiency | XPO5* | Xpo5 | Alliance of Genome Resources | ||||
| primary ovarian insufficiency | BBS9* | Bbs9 | Alliance of Genome Resources | ||||
| primary ovarian insufficiency | MSH4* | Msh4 | Alliance of Genome Resources | ||||
| primary ovarian insufficiency | KASH5* | Kash5 | Alliance of Genome Resources | ||||
| primary ovarian insufficiency | FANCA* | Fanca | Alliance of Genome Resources | ||||
| primary ovarian insufficiency | DIAPH2* | Diaph2 | Alliance of Genome Resources | ||||
| primary ovarian insufficiency | BMP15* | Bmp15 | Alliance of Genome Resources | ||||
| primary ovarian insufficiency | TP63* | Trp63 | Alliance of Genome Resources | ||||
| primary ovarian insufficiency | POLG* | Polg | Alliance of Genome Resources | ||||
| primary ovarian insufficiency 1 | FMR1* | Fmr1 | Alliance of Genome Resources | ||||
| primary ovarian insufficiency 10 | MCM8* | Mcm8 | Alliance of Genome Resources | ||||
| primary ovarian insufficiency 11 | ERCC6* | Ercc6 | Alliance of Genome Resources | ||||
| primary ovarian insufficiency 14 | GDF9* | Gdf9 | Alliance of Genome Resources | ||||
| primary ovarian insufficiency 15 | FANCM* | Fancm | Alliance of Genome Resources | ||||
| primary ovarian insufficiency 16 | BNC1* | Bnc1 | Alliance of Genome Resources | ||||
| primary ovarian insufficiency 17 | XRCC2* | Xrcc2 | Alliance of Genome Resources | ||||
| primary ovarian insufficiency 18 | C14orf39* | 4930447C04Rik | Alliance of Genome Resources | ||||
| primary ovarian insufficiency 2A | DIAPH2* | Diaph2 | Alliance of Genome Resources | ||||
| primary ovarian insufficiency 2B | POF1B* | Pof1b | Alliance of Genome Resources | ||||
| primary ovarian insufficiency 3 | FOXL2* | Foxl2 | Alliance of Genome Resources | ||||
| primary ovarian insufficiency 5 | NOBOX* | Nobox | Alliance of Genome Resources | ||||
| primary ovarian insufficiency 6 | FIGLA* | Figla | Alliance of Genome Resources | ||||
| primary ovarian insufficiency 7 | NR5A1* | Nr5a1 | Alliance of Genome Resources | ||||
| primary ovarian insufficiency 8 | STAG3* | Stag3 | Alliance of Genome Resources | ||||
| primary ovarian insufficiency 9 | HFM1* | Hfm1 | Alliance of Genome Resources | ||||
| testicular cancer | GSTP1* | Gstp1, Gstp2, Gstp3, Gstp-ps | Alliance of Genome Resources | ||||
| testicular lymphoma | MYD88* | Myd88 | Alliance of Genome Resources | ||||
| Turner syndrome | VDR* | Vdr | Alliance of Genome Resources | ||||
| Turner syndrome | IGFBP3* | Igfbp3 | Alliance of Genome Resources | ||||
Excel File
|
Transgenes and other genome features developed in mice to model this disease.
|
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| dermoid cyst of ovary | Tg(Amh-SMAD2*)#Jebu | 1 model | |
| ovarian cancer | Tg(Amhr2-SV40TAg)1Dcco | 1 model | |
| ovarian cancer | Tg(CAG-lacZ,-SV40)#Bcv | 1 model | |
| polycystic ovary syndrome | Tg(Cyp17a1-NGF)2456Oje | 1 model | |