Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Drd2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes DRD2
- Mouse genes Drd2
- Rat genes Drd2
- Zfish genes drd2a,drd2b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Drd2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035240	dopamine binding	Drd2	IDA		Mouse	PMID:15716360
Molecular Function	GO:0035240	dopamine binding	Drd2	IMP		Rat	PMID:17174299\|RGD:1624999
Molecular Function	GO:0004952	dopamine neurotransmitter receptor activity	Drd2	IDA		Mouse	PMID:18671743
Molecular Function	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go	DRD2	IDA		Human	PMID:8301582
Molecular Function	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:11069974
Molecular Function	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go	Drd2	IDA		Mouse	PMID:12930822
Molecular Function	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go	Drd2	IMP	MGI:MGI:3576789	Mouse	PMID:9140068
Molecular Function	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:11172060
Molecular Function	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go	Drd2	IDA		Mouse	PMID:7566118
Molecular Function	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go	Drd2	IDA		Mouse	PMID:8001143
Molecular Function	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go	Drd2	IMP		Mouse	PMID:15721235
Molecular Function	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go	Drd2	IDA		Mouse	PMID:8294904
Molecular Function	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go	Drd2	IDA		Mouse	PMID:8836575
Molecular Function	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:9247268
Molecular Function	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go	Drd2	IDA		Mouse	PMID:1980140
Molecular Function	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go	Drd2	IDA		Mouse	PMID:11015197
Molecular Function	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go	Drd2	IDA		Rat	PMID:2974511\|RGD:728728
Molecular Function	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go	Drd2	IDA		Rat	PMID:8302280\|RGD:8554810
Molecular Function	GO:0004930	G protein-coupled receptor activity	Drd2	IDA		Mouse	PMID:14712229
Molecular Function	GO:1901363	heterocyclic compound binding	Drd2	IPI	CHEBI:6605\|CHEBI:8058\|CHEBI:34725	Rat	PMID:15852061\|RGD:1581406
Molecular Function	GO:0042802	identical protein binding	DRD2	IPI	UniProtKB:P14416	Human	PMID:18668123
Molecular Function	GO:0042802	identical protein binding	DRD2	IPI	UniProtKB:P14416	Human	PMID:23624386
Molecular Function	GO:0042802	identical protein binding	DRD2	IPI	UniProtKB:P14416	Human	PMID:23637801
Molecular Function	GO:0042802	identical protein binding	DRD2	IPI	UniProtKB:P14416	Human	PMID:28734930
Molecular Function	GO:0042802	identical protein binding	Drd2	IPI	RGD:2520	Rat	PMID:20813060\|RGD:6907450
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	Drd2	IPI	RGD:2738	Rat	PMID:17145509\|RGD:1642312
Molecular Function	GO:0097159	organic cyclic compound binding	Drd2	IPI	CHEBI:6121	Rat	PMID:15852061\|RGD:1581406
Molecular Function	GO:0005515	protein binding	DRD2	IPI	UniProtKB:P21333	Human	PMID:10692483
Molecular Function	GO:0005515	protein binding	DRD2	IPI	UniProtKB:Q01959	Human	PMID:17380124
Molecular Function	GO:0005515	protein binding	DRD2	IPI	UniProtKB:Q9NRI5	Human	PMID:32493513
Molecular Function	GO:0005515	protein binding	Drd2	IPI	UniProtKB:Q61616	Mouse	MGI:MGI:5688247\|PMID:25865831
Molecular Function	GO:0005515	protein binding	Drd2	IPI	RGD:632281	Rat	PMID:10391935\|RGD:1358601
Molecular Function	GO:0005515	protein binding	Drd2	IPI	UniProtKB:O35274	Rat	PMID:10391935\|RGD:1358601
Molecular Function	GO:0005515	protein binding	Drd2	IPI	RGD:2157	Rat	PMID:12890920\|RGD:1581347
Molecular Function	GO:0005515	protein binding	Drd2	IPI	RGD:621385	Rat	PMID:12890920\|RGD:1581347
Molecular Function	GO:0005515	protein binding	Drd2	IPI	RGD:727938	Rat	PMID:14499480\|RGD:1302428
Molecular Function	GO:0005515	protein binding	Drd2	IPI	RGD:68338	Rat	PMID:14617818\|RGD:1581465
Molecular Function	GO:0005515	protein binding	Drd2	IPI	RGD:2513	Rat	PMID:14709338\|RGD:9685157
Molecular Function	GO:0005515	protein binding	Drd2	IPI	RGD:71096	Rat	PMID:14709338\|RGD:9685157
Molecular Function	GO:0005515	protein binding	Drd2	IPI	RGD:2157	Rat	PMID:15361545\|RGD:1600943
Molecular Function	GO:0005515	protein binding	Drd2	IPI	RGD:621385	Rat	PMID:15361545\|RGD:1600943
Molecular Function	GO:0005515	protein binding	Drd2	IPI	RGD:1308834	Rat	PMID:17472703\|RGD:2311569
Molecular Function	GO:0005515	protein binding	Drd2	IPI	RGD:3715	Rat	PMID:18256931\|RGD:2311568
Molecular Function	GO:0005515	protein binding	Drd2	IPI	RGD:1305241	Rat	PMID:18346199\|RGD:2311564
Molecular Function	GO:0005515	protein binding	Drd2	IPI	RGD:3615	Rat	PMID:18445708\|RGD:2311563
Molecular Function	GO:0005515	protein binding	Drd2	IPI	UniProtKB:Q9N0H5	Rat	PMID:18809670\|RGD:2311559
Molecular Function	GO:0005515	protein binding	Drd2	IPI	RGD:621859	Rat	PMID:19465068\|RGD:2311555
Molecular Function	GO:0044877	protein-containing complex binding	Drd2	IPI	RGD:2518	Rat	PMID:22986162\|RGD:6907442
Molecular Function	GO:0005102	signaling receptor binding	Drd2	IPI	RGD:2738	Rat	PMID:17145509\|RGD:1642312
Cellular Component	GO:0001669	acrosomal vesicle	Drd2	IDA		Rat	PMID:16924680\|RGD:2311573
Cellular Component	GO:0030424	axon	Drd2	IDA		Mouse	PMID:10051229
Cellular Component	GO:0030424	axon	Drd2	IDA		Rat	PMID:12965226\|RGD:1581421
Cellular Component	GO:0043679	axon terminus	Drd2	IDA		Rat	PMID:7623147\|RGD:2311574
Cellular Component	GO:0060170	ciliary membrane	DRD2	IDA		Human	PMID:20531939
Cellular Component	GO:0005929	cilium	DRD2	IDA		Human	PMID:28154160
Cellular Component	GO:0031410	cytoplasmic vesicle	Drd2	IDA		Rat	PMID:17593530\|RGD:2311571
Cellular Component	GO:0030425	dendrite	Drd2	IDA		Mouse	PMID:10051229
Cellular Component	GO:0030425	dendrite	Drd2	IDA		Rat	PMID:12965226\|RGD:1581421
Cellular Component	GO:0030425	dendrite	Drd2	IDA		Rat	PMID:15224400\|RGD:1600942
Cellular Component	GO:0043197	dendritic spine	Drd2	IDA		Rat	PMID:7623147\|RGD:2311574
Cellular Component	GO:0098691	dopaminergic synapse	Drd2	IDA		Mouse	PMID:12223553
Cellular Component	GO:0098691	dopaminergic synapse	Drd2	EXP		Mouse	PMID:12223553
Cellular Component	GO:0098691	dopaminergic synapse	Drd2	IMP		Mouse	PMID:12223553
Cellular Component	GO:0030139	endocytic vesicle	Drd2	IDA		Rat	PMID:14617818\|RGD:1581465
Cellular Component	GO:0098982	GABA-ergic synapse	Drd2	IDA		Mouse	PMID:27035941
Cellular Component	GO:0098982	GABA-ergic synapse	Drd2	IDA		Rat	PMID:18340460\|RGD:13702291
Cellular Component	GO:0098978	glutamatergic synapse	Drd2	IDA		Mouse	PMID:27035941
Cellular Component	GO:0098978	glutamatergic synapse	Drd2	IDA		Rat	PMID:18340460\|RGD:13702291
Cellular Component	GO:0016328	lateral plasma membrane	Drd2	IDA		Rat	PMID:10391935\|RGD:1358601
Cellular Component	GO:0016020	membrane	Drd2	IDA		Rat	PMID:8302280\|RGD:8554810
Cellular Component	GO:0097730	non-motile cilium	DRD2	IDA		Human	PMID:20531939
Cellular Component	GO:0043204	perikaryon	Drd2	IDA		Rat	PMID:12965226\|RGD:1581421
Cellular Component	GO:0005886	plasma membrane	DRD2	IDA		Human	PMID:26554819
Cellular Component	GO:0005886	plasma membrane	DRD2	IDA		Human	PMID:8413587
Cellular Component	GO:0005886	plasma membrane	Drd2	IDA		Rat	PMID:14499480\|RGD:1302428
Cellular Component	GO:0014069	postsynaptic density	Drd2	IDA		Rat	PMID:17145509\|RGD:1642312
Cellular Component	GO:0045211	postsynaptic membrane	Drd2	IDA		Mouse	PMID:27035941
Cellular Component	GO:0045211	postsynaptic membrane	Drd2	IDA		Rat	PMID:18340460\|RGD:13702291
Cellular Component	GO:0098793	presynapse	Drd2	EXP		Mouse	MGI:MGI:2387277\|PMID:12223553
Cellular Component	GO:0042734	presynaptic membrane	Drd2	IDA		Mouse	PMID:27035941
Cellular Component	GO:0042734	presynaptic membrane	Drd2	IDA		Rat	PMID:18340460\|RGD:13702291
Cellular Component	GO:0036126	sperm flagellum	Drd2	IDA		Rat	PMID:16924680\|RGD:2311573
Cellular Component	GO:0030672	synaptic vesicle membrane	Drd2	IDA		Rat	PMID:7623147\|RGD:2311574
Biological Process	GO:0046717	acid secretion	Drd2	IDA		Rat	PMID:8302280\|RGD:8554810
Biological Process	GO:0032147	activation of protein kinase activity	Drd2	IDA		Rat	PMID:12086672\|RGD:1580677
Biological Process	GO:0021984	adenohypophysis development	Drd2	IMP	MGI:MGI:3576789	Mouse	PMID:9140068
Biological Process	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway	DRD2	IDA		Human	PMID:26554819
Biological Process	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway	DRD2	IDA		Human	PMID:8666994
Biological Process	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway	Drd2	IDA		Mouse	PMID:12665504
Biological Process	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway	Drd2	IGI	MGI:MGI:99673	Mouse	PMID:12223546
Biological Process	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway	Drd2	IGI	MGI:MGI:99578	Mouse	PMID:12223546
Biological Process	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway	Drd2	IDA		Rat	PMID:2410769\|RGD:8553953
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	Drd2	IDA		Rat	PMID:12086672\|RGD:1580677
Biological Process	GO:0030534	adult behavior	Drd2	IMP	MGI:MGI:2656648	Mouse	PMID:11303741
Biological Process	GO:0007628	adult walking behavior	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:7566118
Biological Process	GO:0050482	arachidonic acid secretion	DRD2	IDA		Human	PMID:8301582
Biological Process	GO:0008306	associative learning	Drd2	IMP	MGI:MGI:2656648	Mouse	PMID:12182883
Biological Process	GO:0008306	associative learning	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:15061865
Biological Process	GO:0008306	associative learning	Drd2	IMP	MGI:MGI:2388386	Mouse	PMID:12084937
Biological Process	GO:0031223	auditory behavior	Drd2	IMP		Rat	PMID:17142301\|RGD:1600947
Biological Process	GO:0006914	autophagy	Drd2	IDA		Rat	PMID:26649942\|RGD:13506953
Biological Process	GO:0007409	axonogenesis	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:11438590
Biological Process	GO:0048148	behavioral response to cocaine	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:17426149
Biological Process	GO:0048149	behavioral response to ethanol	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:12837020
Biological Process	GO:0048149	behavioral response to ethanol	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:11105945
Biological Process	GO:0048149	behavioral response to ethanol	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:11166059
Biological Process	GO:0048755	branching morphogenesis of a nerve	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:11438590
Biological Process	GO:0016477	cell migration	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:17409246
Biological Process	GO:0008283	cell population proliferation	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:9247267
Biological Process	GO:0008283	cell population proliferation	Drd2	IMP	MGI:MGI:3576789	Mouse	PMID:9140068
Biological Process	GO:0008283	cell population proliferation	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:9247268
Biological Process	GO:0008283	cell population proliferation	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:10537166
Biological Process	GO:0008283	cell population proliferation	Drd2	IGI	MGI:MGI:97762	Mouse	PMID:9247268
Biological Process	GO:0008283	cell population proliferation	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:9717839
Biological Process	GO:0021853	cerebral cortex GABAergic interneuron migration	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:17409246
Biological Process	GO:0032922	circadian regulation of gene expression	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:16606840
Biological Process	GO:0042417	dopamine metabolic process	Drd2	IMP		Mouse	PMID:7925842
Biological Process	GO:0007212	dopamine receptor signaling pathway	Drd2	IGI	MGI:MGI:99578	Mouse	PMID:12097513
Biological Process	GO:0007212	dopamine receptor signaling pathway	Drd2	IGI	MGI:MGI:94925	Mouse	PMID:12097513
Biological Process	GO:0007212	dopamine receptor signaling pathway	Drd2	IDA		Rat	PMID:12121979\|RGD:1581445
Biological Process	GO:0051583	dopamine uptake involved in synaptic transmission	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:9886065
Biological Process	GO:0042756	drinking behavior	Drd2	IDA		Rat	PMID:12944496\|RGD:1581422
Biological Process	GO:0050673	epithelial cell proliferation	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:9247268
Biological Process	GO:0050673	epithelial cell proliferation	Drd2	IGI	MGI:MGI:97762	Mouse	PMID:9247268
Biological Process	GO:0007631	feeding behavior	Drd2	IGI	MGI:MGI:99578	Mouse	PMID:15272078
Biological Process	GO:0030900	forebrain development	Drd2	IMP		Rat	PMID:17175142\|RGD:2311572
Biological Process	GO:0002031	G protein-coupled receptor internalization	Drd2	IDA		Rat	PMID:14617818\|RGD:1581465
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Drd2	IDA		Mouse	PMID:14712229
Biological Process	GO:0007625	grooming behavior	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:10698004
Biological Process	GO:1990384	hyaloid vascular plexus regression	Drd2	IMP		Mouse	MGI:MGI:6359287\|PMID:30936473
Biological Process	GO:0007626	locomotory behavior	Drd2	IGI	MGI:MGI:1351342	Mouse	PMID:16280580
Biological Process	GO:0007626	locomotory behavior	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:11557166
Biological Process	GO:0007626	locomotory behavior	Drd2	IGI	MGI:MGI:99578	Mouse	PMID:15272078
Biological Process	GO:0007626	locomotory behavior	Drd2	IGI	MGI:MGI:94925	Mouse	PMID:11864730
Biological Process	GO:0007626	locomotory behavior	Drd2	IGI	MGI:MGI:94925	Mouse	PMID:9354330
Biological Process	GO:0007626	locomotory behavior	Drd2	IGI	MGI:MGI:99402	Mouse	PMID:16280580
Biological Process	GO:0007626	locomotory behavior	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:9547254
Biological Process	GO:0007626	locomotory behavior	Drd2	IMP	MGI:MGI:2388386	Mouse	PMID:12084937
Biological Process	GO:0007626	locomotory behavior	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:12837020
Biological Process	GO:0007626	locomotory behavior	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:12175868
Biological Process	GO:0007626	locomotory behavior	Drd2	IGI	MGI:MGI:99578	Mouse	PMID:9354330
Biological Process	GO:0007626	locomotory behavior	Drd2	IGI	MGI:MGI:94862	Mouse	PMID:11150348
Biological Process	GO:0007626	locomotory behavior	Drd2	IGI	MGI:MGI:99402	Mouse	PMID:10908627
Biological Process	GO:0007626	locomotory behavior	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:10471093
Biological Process	GO:0007626	locomotory behavior	Drd2	IMP		Mouse	PMID:12185400
Biological Process	GO:0007626	locomotory behavior	Drd2	IGI	MGI:MGI:99402	Mouse	PMID:11172060
Biological Process	GO:0007626	locomotory behavior	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:10698004
Biological Process	GO:0007626	locomotory behavior	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:11166059
Biological Process	GO:0007626	locomotory behavior	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:15080900
Biological Process	GO:0007626	locomotory behavior	Drd2	IMP		Rat	PMID:16530737\|RGD:1600944
Biological Process	GO:0007616	long-term memory	Drd2	IMP		Rat	PMID:17118678\|RGD:1624997
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:10974427
Biological Process	GO:0045776	negative regulation of blood pressure	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:11566895
Biological Process	GO:0008285	negative regulation of cell population proliferation	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:10537166
Biological Process	GO:0008285	negative regulation of cell population proliferation	Drd2	IMP	MGI:MGI:3576789	Mouse	PMID:9140068
Biological Process	GO:0008285	negative regulation of cell population proliferation	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:9247267
Biological Process	GO:0008285	negative regulation of cell population proliferation	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:9247268
Biological Process	GO:0008285	negative regulation of cell population proliferation	Drd2	IGI	MGI:MGI:97762	Mouse	PMID:9247268
Biological Process	GO:0008285	negative regulation of cell population proliferation	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:9717839
Biological Process	GO:1900038	negative regulation of cellular response to hypoxia	Drd2	IMP		Rat	PMID:27638511\|RGD:13506952
Biological Process	GO:0042321	negative regulation of circadian sleep/wake cycle, sleep	Drd2	IDA		Rat	PMID:12944496\|RGD:1581422
Biological Process	GO:0051481	negative regulation of cytosolic calcium ion concentration	Drd2	IMP		Rat	PMID:15681393\|RGD:1581407
Biological Process	GO:0060160	negative regulation of dopamine receptor signaling pathway	Drd2	IGI	MGI:MGI:94925	Mouse	PMID:12097513
Biological Process	GO:0060160	negative regulation of dopamine receptor signaling pathway	Drd2	IGI	MGI:MGI:99578	Mouse	PMID:12097513
Biological Process	GO:0033602	negative regulation of dopamine secretion	Drd2	IMP		Rat	PMID:16490190\|RGD:1625068
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	Drd2	IGI	MGI:MGI:97762	Mouse	PMID:9247268
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:9247268
Biological Process	GO:0045824	negative regulation of innate immune response	Drd2	IMP		Mouse	MGI:MGI:5473736\|PMID:23242137
Biological Process	GO:0046676	negative regulation of insulin secretion	Drd2	IMP		Rat	PMID:18216393\|RGD:2311570
Biological Process	GO:2001223	negative regulation of neuron migration	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:17409246
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	Drd2	IMP	MGI:MGI:2675755	Mouse	PMID:17251429
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:17251429
Biological Process	GO:0001933	negative regulation of protein phosphorylation	Drd2	IMP		Rat	PMID:26277342\|RGD:11533440
Biological Process	GO:0050709	negative regulation of protein secretion	DRD2	IDA		Human	PMID:16839358
Biological Process	GO:0050805	negative regulation of synaptic transmission	Drd2	IDA		Rat	PMID:17314300\|RGD:1625010
Biological Process	GO:0051967	negative regulation of synaptic transmission, glutamatergic	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:11160501
Biological Process	GO:1901386	negative regulation of voltage-gated calcium channel activity	Drd2	IDA		Rat	PMID:2162345\|RGD:8554169
Biological Process	GO:0001976	nervous system process involved in regulation of systemic arterial blood pressure	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:11566895
Biological Process	GO:0007405	neuroblast proliferation	Drd2	IDA		Mouse	PMID:17426594
Biological Process	GO:0001764	neuron migration	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:17409246
Biological Process	GO:0007270	neuron-neuron synaptic transmission	Drd2	IMP	MGI:MGI:2388386	Mouse	PMID:12084937
Biological Process	GO:0021769	orbitofrontal cortex development	Drd2	IEP		Rat	PMID:22015925\|RGD:7248608
Biological Process	GO:0030432	peristalsis	Drd2	IMP	MGI:MGI:2388386	Mouse	PMID:16525059
Biological Process	GO:0030432	peristalsis	Drd2	IGI	MGI:MGI:99578	Mouse	PMID:15272078
Biological Process	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway	DRD2	IGI	UniProtKB:P21728	Human	PMID:17194762
Biological Process	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway	Drd2	IGI	MGI:MGI:95776	Mouse	PMID:17194762
Biological Process	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway	Drd2	IGI	MGI:MGI:95766	Mouse	PMID:17194762
Biological Process	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway	Drd2	IDA		Mouse	PMID:15016423
Biological Process	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway	Drd2	IGI	MGI:MGI:99578	Mouse	PMID:17194762
Biological Process	GO:0043473	pigmentation	Drd2	IMP	MGI:MGI:3576789	Mouse	PMID:9140068
Biological Process	GO:0032467	positive regulation of cytokinesis	DRD2	IMP		Human	PMID:22888021
Biological Process	GO:0051586	positive regulation of dopamine uptake involved in synaptic transmission	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:9886065
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Drd2	IMP		Rat	PMID:18809670\|RGD:2311559
Biological Process	GO:0045745	positive regulation of G protein-coupled receptor signaling pathway	Drd2	IMP		Rat	PMID:18809670\|RGD:2311559
Biological Process	GO:1900168	positive regulation of glial cell-derived neurotrophic factor production	DRD2	IDA		Human	PMID:23373701
Biological Process	GO:0060124	positive regulation of growth hormone secretion	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:11897683
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	Drd2	IMP		Rat	PMID:20377617\|RGD:6907453
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:11897683
Biological Process	GO:0002052	positive regulation of neuroblast proliferation	Drd2	IDA		Mouse	PMID:17426594
Biological Process	GO:0050769	positive regulation of neurogenesis	Drd2	IDA		Rat	PMID:27638511\|RGD:13506952
Biological Process	GO:0002092	positive regulation of receptor internalization	Drd2	IMP		Rat	PMID:18809670\|RGD:2311559
Biological Process	GO:0035815	positive regulation of renal sodium excretion	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:11566895
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Drd2	IDA		Rat	PMID:12388421\|RGD:629546
Biological Process	GO:0035810	positive regulation of urine volume	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:11566895
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	Drd2	EXP		Rat	PMID:15175382\|RGD:13702391
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	Drd2	IDA		Rat	PMID:15175382\|RGD:13702391
Biological Process	GO:0060134	prepulse inhibition	Drd2	IMP		Mouse	PMID:17712281
Biological Process	GO:0060134	prepulse inhibition	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:10341260
Biological Process	GO:0060134	prepulse inhibition	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:12417685
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Drd2	IDA		Mouse	PMID:22586226
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Drd2	EXP		Mouse	PMID:22586226
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Drd2	EXP		Mouse	PMID:12223553
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Drd2	IMP		Mouse	PMID:12223553
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Drd2	IDA		Mouse	PMID:12223553
Biological Process	GO:0043491	protein kinase B signaling	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:17251429
Biological Process	GO:0043491	protein kinase B signaling	Drd2	IMP	MGI:MGI:2675755	Mouse	PMID:17251429
Biological Process	GO:0008104	protein localization	Drd2	IMP	MGI:MGI:2388386	Mouse	PMID:10828532
Biological Process	GO:0051584	regulation of dopamine uptake involved in synaptic transmission	Drd2	IMP	MGI:MGI:2388386	Mouse	PMID:12223553
Biological Process	GO:0002027	regulation of heart rate	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:11566895
Biological Process	GO:0090325	regulation of locomotion involved in locomotory behavior	Drd2	IMP		Rat	PMID:22394078\|RGD:6907452
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:9169514
Biological Process	GO:0043408	regulation of MAPK cascade	Drd2	IDA		Rat	PMID:12121979\|RGD:1581445
Biological Process	GO:0051580	regulation of neurotransmitter uptake	Drd2	IMP		Mouse	PMID:12223553
Biological Process	GO:0051580	regulation of neurotransmitter uptake	Drd2	EXP		Mouse	PMID:12223553
Biological Process	GO:0051580	regulation of neurotransmitter uptake	Drd2	IDA		Mouse	PMID:12223553
Biological Process	GO:0043666	regulation of phosphoprotein phosphatase activity	Drd2	IMP		Rat	PMID:12435803\|RGD:633811
Biological Process	GO:0043266	regulation of potassium ion transport	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:11566895
Biological Process	GO:0043266	regulation of potassium ion transport	Drd2	IDA		Rat	PMID:2162345\|RGD:8554169
Biological Process	GO:0043266	regulation of potassium ion transport	Drd2	IDA		Rat	PMID:8371717\|RGD:8554702
Biological Process	GO:0002028	regulation of sodium ion transport	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:11566895
Biological Process	GO:0051823	regulation of synapse structural plasticity	Drd2	IDA		Rat	PMID:22216301\|RGD:6907446
Biological Process	GO:0032228	regulation of synaptic transmission, GABAergic	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:15080900
Biological Process	GO:0032228	regulation of synaptic transmission, GABAergic	Drd2	IGI	MGI:MGI:99402	Mouse	PMID:10934242
Biological Process	GO:0051209	release of sequestered calcium ion into cytosol	Drd2	IMP		Rat	PMID:8371717\|RGD:8554702
Biological Process	GO:0001975	response to amphetamine	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:18486343
Biological Process	GO:0001975	response to amphetamine	Drd2	IGI	MGI:MGI:94925	Mouse	PMID:12097513
Biological Process	GO:0001975	response to amphetamine	Drd2	IGI	MGI:MGI:99578	Mouse	PMID:12097513
Biological Process	GO:0001975	response to amphetamine	Drd2	IEP		Rat	PMID:19145071\|RGD:2311558
Biological Process	GO:0048678	response to axon injury	Drd2	IEP		Rat	PMID:19500946\|RGD:2311554
Biological Process	GO:0042220	response to cocaine	Drd2	IDA		Mouse	PMID:18671743
Biological Process	GO:0042220	response to cocaine	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:11923462
Biological Process	GO:0042220	response to cocaine	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:12185400
Biological Process	GO:0045471	response to ethanol	Drd2	IEP		Rat	PMID:18536982\|RGD:2311561
Biological Process	GO:0034776	response to histamine	DRD2	IDA		Human	PMID:16839358
Biological Process	GO:0001666	response to hypoxia	Drd2	IMP		Rat	PMID:15681393\|RGD:1581407
Biological Process	GO:0014854	response to inactivity	Drd2	IEP		Rat	PMID:17511973\|RGD:2311589
Biological Process	GO:0010039	response to iron ion	Drd2	IEP		Rat	PMID:19022977\|RGD:2311557
Biological Process	GO:0009416	response to light stimulus	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:16715079
Biological Process	GO:0043278	response to morphine	Drd2	IMP	MGI:MGI:2388386	Mouse	PMID:11567069
Biological Process	GO:0043278	response to morphine	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:9252189
Biological Process	GO:0043278	response to morphine	Drd2	IMP	MGI:MGI:2656648	Mouse	PMID:12182883
Biological Process	GO:0043278	response to morphine	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:11264672
Biological Process	GO:0035094	response to nicotine	Drd2	IEP		Rat	PMID:19406037\|RGD:2311556
Biological Process	GO:0009636	response to toxic substance	Drd2	IEP		Rat	PMID:19576243\|RGD:2311553
Biological Process	GO:0009410	response to xenobiotic stimulus	Drd2	IDA		Mouse	PMID:7549459
Biological Process	GO:0009410	response to xenobiotic stimulus	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:16136297
Biological Process	GO:0009410	response to xenobiotic stimulus	Drd2	IDA		Rat	PMID:1975644\|RGD:728430
Biological Process	GO:0007608	sensory perception of smell	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:16765459
Biological Process	GO:0001964	startle response	Drd2	IMP		Mouse	PMID:17712281
Biological Process	GO:0021756	striatum development	Drd2	IEP		Rat	PMID:22015925\|RGD:7248608
Biological Process	GO:0007416	synapse assembly	Drd2	IEP		Rat	PMID:10051231\|RGD:8554073
Biological Process	GO:0001659	temperature homeostasis	Drd2	IMP	MGI:MGI:2387895	Mouse	PMID:10471093
Biological Process	GO:0001659	temperature homeostasis	Drd2	IMP	MGI:MGI:1857875	Mouse	PMID:18486343
Biological Process	GO:0008542	visual learning	Drd2	IMP	MGI:MGI:2388386	Mouse	PMID:12097513
Biological Process	GO:0016055	Wnt signaling pathway	Drd2	IDA		Rat	PMID:17472703\|RGD:2311569

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.