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Gene Ontology Browser
Term Detail
GO term:autophagy
Synonym: chaperone-mediated autophagy
GO id:GO:0006914
Definition:The process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
Number of paths to term: 3

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-acellular catabolic process
                                        is-aaldehyde catabolic process +
                                        is-aalkane catabolic process +
                                        is-aalkene catabolic process +
                                        is-aalkyne catabolic process +
                                        is-aantibiotic catabolic process +
                                        is-aaromatic compound catabolic process +
                                        is-aautophagy [GO:0006914] (162 genes, 327 annotations)
                                                is-aautophagy in response to ER overload
                                                is-aautophagy involved in symbiotic interaction +
                                                is-amacroautophagy +
                                                is-amicroautophagy +
                                                is-amitochondrion degradation +
                                                negatively-regulatesnegative regulation of autophagy +
                                                is-anucleophagy +
                                                is-aperoxisome degradation +
                                                positively-regulatespositive regulation of autophagy +
                                                part-ofprotein targeting to vacuole involved in autophagy
                                                regulatesregulation of autophagy +
                                                is-aribophagy
                                        is-acell septum edging catabolic process
                                        is-acell wall macromolecule catabolic process +
                                        is-acellular alcohol catabolic process +
                                        is-acellular lipid catabolic process +
                                        is-acellular macromolecule catabolic process +
                                        is-acellular nitrogen compound catabolic process +
                                        is-acofactor catabolic process +
                                        is-adrug catabolic process +
                                        is-aglycerol ether catabolic process
                                        is-aheterocycle catabolic process +
                                        is-ahydrogen peroxide catabolic process +
                                        is-aketone body catabolic process +
                                        is-aketone catabolic process +
                                        negatively-regulatesnegative regulation of cellular catabolic process +
                                        is-aneurotransmitter catabolic process +
                                        is-aorganic acid catabolic process +
                                        is-aorganomercury catabolic process +
                                        is-apeptide catabolic process +
                                        is-apeptidyl-diphthamide catabolic process
                                        is-apeptidyl-diphthine catabolic process
                                        is-apheromone catabolic process
                                        is-apolyphosphate catabolic process
                                        positively-regulatespositive regulation of cellular catabolic process +
                                        is-areceptor catabolic process +
                                        regulatesregulation of cellular catabolic process +
                                        is-asulfur compound catabolic process +
                                        is-atoxin catabolic process +
                                        is-avitamin catabolic process +
                                        is-axenobiotic catabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acatabolic process
                                is-acellular catabolic process
                                        is-aaldehyde catabolic process +
                                        is-aalkane catabolic process +
                                        is-aalkene catabolic process +
                                        is-aalkyne catabolic process +
                                        is-aantibiotic catabolic process +
                                        is-aaromatic compound catabolic process +
                                        is-aautophagy [GO:0006914] (162 genes, 327 annotations)
                                                is-aautophagy in response to ER overload
                                                is-aautophagy involved in symbiotic interaction +
                                                is-amacroautophagy +
                                                is-amicroautophagy +
                                                is-amitochondrion degradation +
                                                negatively-regulatesnegative regulation of autophagy +
                                                is-anucleophagy +
                                                is-aperoxisome degradation +
                                                positively-regulatespositive regulation of autophagy +
                                                part-ofprotein targeting to vacuole involved in autophagy
                                                regulatesregulation of autophagy +
                                                is-aribophagy
                                        is-acell septum edging catabolic process
                                        is-acell wall macromolecule catabolic process +
                                        is-acellular alcohol catabolic process +
                                        is-acellular lipid catabolic process +
                                        is-acellular macromolecule catabolic process +
                                        is-acellular nitrogen compound catabolic process +
                                        is-acofactor catabolic process +
                                        is-adrug catabolic process +
                                        is-aglycerol ether catabolic process
                                        is-aheterocycle catabolic process +
                                        is-ahydrogen peroxide catabolic process +
                                        is-aketone body catabolic process +
                                        is-aketone catabolic process +
                                        negatively-regulatesnegative regulation of cellular catabolic process +
                                        is-aneurotransmitter catabolic process +
                                        is-aorganic acid catabolic process +
                                        is-aorganomercury catabolic process +
                                        is-apeptide catabolic process +
                                        is-apeptidyl-diphthamide catabolic process
                                        is-apeptidyl-diphthine catabolic process
                                        is-apheromone catabolic process
                                        is-apolyphosphate catabolic process
                                        positively-regulatespositive regulation of cellular catabolic process +
                                        is-areceptor catabolic process +
                                        regulatesregulation of cellular catabolic process +
                                        is-asulfur compound catabolic process +
                                        is-atoxin catabolic process +
                                        is-avitamin catabolic process +
                                        is-axenobiotic catabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-acellular catabolic process
                                        is-aaldehyde catabolic process +
                                        is-aalkane catabolic process +
                                        is-aalkene catabolic process +
                                        is-aalkyne catabolic process +
                                        is-aantibiotic catabolic process +
                                        is-aaromatic compound catabolic process +
                                        is-aautophagy [GO:0006914] (162 genes, 327 annotations)
                                                is-aautophagy in response to ER overload
                                                is-aautophagy involved in symbiotic interaction +
                                                is-amacroautophagy +
                                                is-amicroautophagy +
                                                is-amitochondrion degradation +
                                                negatively-regulatesnegative regulation of autophagy +
                                                is-anucleophagy +
                                                is-aperoxisome degradation +
                                                positively-regulatespositive regulation of autophagy +
                                                part-ofprotein targeting to vacuole involved in autophagy
                                                regulatesregulation of autophagy +
                                                is-aribophagy
                                        is-acell septum edging catabolic process
                                        is-acell wall macromolecule catabolic process +
                                        is-acellular alcohol catabolic process +
                                        is-acellular lipid catabolic process +
                                        is-acellular macromolecule catabolic process +
                                        is-acellular nitrogen compound catabolic process +
                                        is-acofactor catabolic process +
                                        is-adrug catabolic process +
                                        is-aglycerol ether catabolic process
                                        is-aheterocycle catabolic process +
                                        is-ahydrogen peroxide catabolic process +
                                        is-aketone body catabolic process +
                                        is-aketone catabolic process +
                                        negatively-regulatesnegative regulation of cellular catabolic process +
                                        is-aneurotransmitter catabolic process +
                                        is-aorganic acid catabolic process +
                                        is-aorganomercury catabolic process +
                                        is-apeptide catabolic process +
                                        is-apeptidyl-diphthamide catabolic process
                                        is-apeptidyl-diphthine catabolic process
                                        is-apheromone catabolic process
                                        is-apolyphosphate catabolic process
                                        positively-regulatespositive regulation of cellular catabolic process +
                                        is-areceptor catabolic process +
                                        regulatesregulation of cellular catabolic process +
                                        is-asulfur compound catabolic process +
                                        is-atoxin catabolic process +
                                        is-avitamin catabolic process +
                                        is-axenobiotic catabolic process +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory