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Term Detail
GO term:G-protein coupled receptor activity
Synonym: EBV-induced receptor
Synonym: Epstein-Barr Virus-induced receptor activity
Synonym: GPCR activity
Synonym: G protein coupled receptor activity
Synonym: G-protein-coupled receptor activity
Synonym: G-protein coupled receptor activity, unknown ligand
Synonym: G protein linked receptor activity
Synonym: G-protein linked receptor activity
Synonym: ligand-dependent GPCR activity
Synonym: Mas proto-oncogene receptor activity
Synonym: orphan GPCR activity
Synonym: orphan G protein coupled receptor activity
Synonym: orphan G-protein coupled receptor activity
Synonym: RDC1 receptor activity
Synonym: receptor activity, G-protein coupled
Synonym: SREB receptor
Synonym: super conserved receptor expressed in brain receptor activity
GO id:GO:0004930
Definition:Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-amolecular transducer activity
                        is-asignal transducer activity
                                is-asignaling receptor activity
                                        is-atransmembrane signaling receptor activity
                                                is-aacetylcholine receptor activity +
                                                is-aapolipoprotein A-I receptor activity
                                                is-aaxon guidance receptor activity
                                                is-acollagen receptor activity +
                                                is-acomplement receptor activity +
                                                is-acytokine receptor activity +
                                                is-acytokinin receptor activity +
                                                is-adeath receptor activity +
                                                is-aG-protein coupled receptor activity [GO:0004930] (1785 genes, 2294 annotations)
                                                        is-aadenylate cyclase inhibiting G-protein coupled glutamate receptor activity +
                                                        is-abioactive lipid receptor activity +
                                                        is-acalcitonin gene-related polypeptide receptor activity
                                                        is-acannabinoid receptor activity
                                                        is-acorticotrophin-releasing factor receptor activity
                                                        is-adopamine neurotransmitter receptor activity +
                                                        is-aecdysis-triggering hormone receptor activity
                                                        is-aG-protein coupled adenosine receptor activity +
                                                        is-aG-protein coupled amine receptor activity +
                                                        is-aG-protein coupled bile acid receptor activity
                                                        is-aG-protein coupled cytokinin receptor activity
                                                        is-aG-protein coupled estrogen receptor activity
                                                        is-aG-protein coupled GABA receptor activity
                                                        is-aG-protein coupled nucleotide receptor activity +
                                                        is-aG-protein coupled olfactory receptor activity
                                                        is-aG-protein coupled peptide receptor activity +
                                                        is-aG-protein coupled photoreceptor activity
                                                        is-agastric inhibitory peptide receptor activity
                                                        is-agrowth hormone secretagogue receptor activity
                                                        is-agrowth hormone-releasing hormone receptor activity
                                                        is-aicosanoid receptor activity +
                                                        is-amelatonin receptor activity
                                                        is-anicotinic acid receptor activity
                                                        is-aparathyroid hormone receptor activity
                                                        is-apheromone receptor activity +
                                                        is-apituitary adenylate cyclase-activating polypeptide receptor activity
                                                        is-aplatelet activating factor receptor activity
                                                        is-aprotein-hormone receptor activity +
                                                        is-asecretin receptor activity
                                                        is-ataste receptor activity +
                                                        is-athyrotropin-releasing hormone receptor activity
                                                        is-avasoactive intestinal polypeptide receptor activity
                                                is-aGABA receptor activity +
                                                is-aglutamate receptor activity +
                                                is-ahedgehog receptor activity
                                                is-aICAM-3 receptor activity
                                                is-aimmunoglobulin receptor activity +
                                                is-alatrotoxin receptor activity
                                                is-aMHC class I receptor activity +
                                                is-aMHC class Ib receptor activity
                                                is-aMHC class II receptor activity
                                                is-anetrin receptor activity +
                                                is-aneuregulin receptor activity
                                                is-aneurotensin receptor activity, non-G-protein coupled
                                                is-anon-tyrosine kinase fibroblast growth factor receptor activity
                                                is-anucleotide receptor activity +
                                                is-aolfactory receptor activity +
                                                is-aopsonin receptor activity +
                                                is-aosmosensor activity
                                                is-apurinergic receptor activity +
                                                is-areelin receptor activity
                                                is-asemaphorin receptor activity
                                                is-asulfonylurea receptor activity
                                                is-atiggrin receptor activity
                                                is-atransmembrane receptor protein kinase activity +
                                                is-atransmembrane receptor protein phosphatase activity +
                                                is-aWnt-activated receptor activity


Gene_Ontology
        is-amolecular_function
                is-areceptor activity
                        is-asignaling receptor activity
                                is-atransmembrane signaling receptor activity
                                        is-aacetylcholine receptor activity +
                                        is-aapolipoprotein A-I receptor activity
                                        is-aaxon guidance receptor activity
                                        is-acollagen receptor activity +
                                        is-acomplement receptor activity +
                                        is-acytokine receptor activity +
                                        is-acytokinin receptor activity +
                                        is-adeath receptor activity +
                                        is-aG-protein coupled receptor activity [GO:0004930] (1785 genes, 2294 annotations)
                                                is-aadenylate cyclase inhibiting G-protein coupled glutamate receptor activity +
                                                is-abioactive lipid receptor activity +
                                                is-acalcitonin gene-related polypeptide receptor activity
                                                is-acannabinoid receptor activity
                                                is-acorticotrophin-releasing factor receptor activity
                                                is-adopamine neurotransmitter receptor activity +
                                                is-aecdysis-triggering hormone receptor activity
                                                is-aG-protein coupled adenosine receptor activity +
                                                is-aG-protein coupled amine receptor activity +
                                                is-aG-protein coupled bile acid receptor activity
                                                is-aG-protein coupled cytokinin receptor activity
                                                is-aG-protein coupled estrogen receptor activity
                                                is-aG-protein coupled GABA receptor activity
                                                is-aG-protein coupled nucleotide receptor activity +
                                                is-aG-protein coupled olfactory receptor activity
                                                is-aG-protein coupled peptide receptor activity +
                                                is-aG-protein coupled photoreceptor activity
                                                is-agastric inhibitory peptide receptor activity
                                                is-agrowth hormone secretagogue receptor activity
                                                is-agrowth hormone-releasing hormone receptor activity
                                                is-aicosanoid receptor activity +
                                                is-amelatonin receptor activity
                                                is-anicotinic acid receptor activity
                                                is-aparathyroid hormone receptor activity
                                                is-apheromone receptor activity +
                                                is-apituitary adenylate cyclase-activating polypeptide receptor activity
                                                is-aplatelet activating factor receptor activity
                                                is-aprotein-hormone receptor activity +
                                                is-asecretin receptor activity
                                                is-ataste receptor activity +
                                                is-athyrotropin-releasing hormone receptor activity
                                                is-avasoactive intestinal polypeptide receptor activity
                                        is-aGABA receptor activity +
                                        is-aglutamate receptor activity +
                                        is-ahedgehog receptor activity
                                        is-aICAM-3 receptor activity
                                        is-aimmunoglobulin receptor activity +
                                        is-alatrotoxin receptor activity
                                        is-aMHC class I receptor activity +
                                        is-aMHC class Ib receptor activity
                                        is-aMHC class II receptor activity
                                        is-anetrin receptor activity +
                                        is-aneuregulin receptor activity
                                        is-aneurotensin receptor activity, non-G-protein coupled
                                        is-anon-tyrosine kinase fibroblast growth factor receptor activity
                                        is-anucleotide receptor activity +
                                        is-aolfactory receptor activity +
                                        is-aopsonin receptor activity +
                                        is-aosmosensor activity
                                        is-apurinergic receptor activity +
                                        is-areelin receptor activity
                                        is-asemaphorin receptor activity
                                        is-asulfonylurea receptor activity
                                        is-atiggrin receptor activity
                                        is-atransmembrane receptor protein kinase activity +
                                        is-atransmembrane receptor protein phosphatase activity +
                                        is-aWnt-activated receptor activity


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory