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Gene Ontology Browser
Term Detail
GO term:cilium
Synonym: eukaryotic flagellum
Synonym: flagellum
Synonym: microtubule-based flagellum
Synonym: primary cilium
GO id:GO:0005929
Alternate id: GO:0072372
Definition:A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
CommentsNote that we deem cilium and microtubule-based flagellum to be equivalent. In most eukaryotic species, intracellular sub-components of the cilium, such as the ciliary base and rootlet, are located near the plasma membrane. In Diplomonads such as Giardia, instead, the same ciliary parts are located further intracellularly. Also, 'cilium' may be used when axonemal structure and/or motility are unknown, or when axonemal structure is unusual. For all other cases, please refer to children of 'cilium'. Finally, note that any role of ciliary proteins in sensory events should be captured by annotating to relevant biological process terms.
Number of paths to term: 3

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-acell projection
                                        is-aaccessory outer segment
                                        is-aactin-based cell projection +
                                        is-aarchaeal-type flagellum
                                        is-abacterial-type flagellum +
                                        is-ableb
                                        is-acell hair
                                        part-ofcell projection cytoplasm +
                                        part-ofcell projection part +
                                        part-ofciliary basal body +
                                        is-acilium [GO:0005929] (517 genes, 1085 annotations)
                                                part-ofBBSome
                                                part-ofciliary part +
                                                part-ofciliary transition zone +
                                                is-amotile cilium +
                                                is-anon-motile cilium +
                                        is-acytoneme
                                        is-adendritic cell dendrite
                                        is-adinoflagellate peduncle
                                        is-aglial cell projection +
                                        is-ahaustorium +
                                        is-ainvadopodium +
                                        is-alamellipodium +
                                        is-amacropinocytic cup +
                                        is-amating projection +
                                        is-amicrospike
                                        is-amuscle cell projection +
                                        is-aneuron projection +
                                        is-aoral apparatus +
                                        is-apilus +
                                        is-aplant cell papilla +
                                        is-apodocyte foot
                                        is-apodocyte primary projection
                                        is-apollen tube +
                                        is-apseudopodium +
                                        is-arhabdomere +
                                        is-aroot hair +
                                        is-aruffle +
                                        is-auropod +


obsolete Gene_Ontology
        is-acellular_component
                is-acell part
                        is-acell projection
                                is-aaccessory outer segment
                                is-aactin-based cell projection +
                                is-aarchaeal-type flagellum
                                is-abacterial-type flagellum +
                                is-ableb
                                is-acell hair
                                part-ofcell projection cytoplasm +
                                part-ofcell projection part +
                                part-ofciliary basal body +
                                is-acilium [GO:0005929] (517 genes, 1085 annotations)
                                        part-ofBBSome
                                        part-ofciliary part +
                                        part-ofciliary transition zone +
                                        is-amotile cilium +
                                        is-anon-motile cilium +
                                is-acytoneme
                                is-adendritic cell dendrite
                                is-adinoflagellate peduncle
                                is-aglial cell projection +
                                is-ahaustorium +
                                is-ainvadopodium +
                                is-alamellipodium +
                                is-amacropinocytic cup +
                                is-amating projection +
                                is-amicrospike
                                is-amuscle cell projection +
                                is-aneuron projection +
                                is-aoral apparatus +
                                is-apilus +
                                is-aplant cell papilla +
                                is-apodocyte foot
                                is-apodocyte primary projection
                                is-apollen tube +
                                is-apseudopodium +
                                is-arhabdomere +
                                is-aroot hair +
                                is-aruffle +
                                is-auropod +


obsolete Gene_Ontology
        is-acellular_component
                is-aorganelle
                        is-acilium [GO:0005929] (517 genes, 1085 annotations)
                                part-ofBBSome
                                part-ofciliary part +
                                part-ofciliary transition zone +
                                is-amotile cilium +
                                is-anon-motile cilium +
                        is-aextracellular organelle +
                        is-aintracellular organelle +
                        is-amembrane-bounded organelle +
                        is-anon-membrane-bounded organelle +
                        part-oforganellar ribosome +
                        part-oforganelle lumen +
                        part-oforganelle part +
                        is-apostsynaptic specialization +
                        is-aventral disc +


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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory