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Gene Ontology Browser
Term Detail
GO term:prepulse inhibition
Synonym: PPI
Synonym: pre-pulse inhibition
GO id:GO:0060134
Definition:The process in which a startle magnitude is reduced when the startling stimulus is preceded by a low-intensity prepulse.
Number of paths to term: 15

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-anegative regulation of biological process
                                        is-anegative regulation of response to stimulus
                                                is-anegative regulation of response to external stimulus
                                                        is-anegative regulation of antimicrobial humoral response
                                                        is-anegative regulation of axon regeneration +
                                                        is-anegative regulation of chemotaxis +
                                                        is-anegative regulation of defense response to bacterium +
                                                        is-anegative regulation of defense response to insect
                                                        is-anegative regulation of defense response to oomycetes
                                                        is-anegative regulation of defense response to virus +
                                                        is-anegative regulation of inflammatory response +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of neutrophil mediated killing of symbiont cell +
                                                        is-anegative regulation of response to extracellular stimulus +
                                                        is-anegative regulation of systemic acquired resistance
                                                        is-anegative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                        is-anegative regulation of wound healing +
                                                        is-aprepulse inhibition [GO:0060134] (13 genes, 14 annotations)


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of response to stimulus
                                        is-anegative regulation of response to stimulus
                                                is-anegative regulation of response to external stimulus
                                                        is-anegative regulation of antimicrobial humoral response
                                                        is-anegative regulation of axon regeneration +
                                                        is-anegative regulation of chemotaxis +
                                                        is-anegative regulation of defense response to bacterium +
                                                        is-anegative regulation of defense response to insect
                                                        is-anegative regulation of defense response to oomycetes
                                                        is-anegative regulation of defense response to virus +
                                                        is-anegative regulation of inflammatory response +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of neutrophil mediated killing of symbiont cell +
                                                        is-anegative regulation of response to extracellular stimulus +
                                                        is-anegative regulation of systemic acquired resistance
                                                        is-anegative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                        is-anegative regulation of wound healing +
                                                        is-aprepulse inhibition [GO:0060134] (13 genes, 14 annotations)


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of response to stimulus
                                        is-aregulation of response to external stimulus
                                                is-anegative regulation of response to external stimulus
                                                        is-anegative regulation of antimicrobial humoral response
                                                        is-anegative regulation of axon regeneration +
                                                        is-anegative regulation of chemotaxis +
                                                        is-anegative regulation of defense response to bacterium +
                                                        is-anegative regulation of defense response to insect
                                                        is-anegative regulation of defense response to oomycetes
                                                        is-anegative regulation of defense response to virus +
                                                        is-anegative regulation of inflammatory response +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of neutrophil mediated killing of symbiont cell +
                                                        is-anegative regulation of response to extracellular stimulus +
                                                        is-anegative regulation of systemic acquired resistance
                                                        is-anegative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                        is-anegative regulation of wound healing +
                                                        is-aprepulse inhibition [GO:0060134] (13 genes, 14 annotations)


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-asystem process
                                        is-aneurological system process
                                                is-aneuromuscular process
                                                        is-astartle response
                                                                part-ofprepulse inhibition [GO:0060134] (13 genes, 14 annotations)


Gene_Ontology
        is-abiological_process
                negatively-regulatesnegative regulation of biological process
                        is-anegative regulation of response to stimulus
                                is-anegative regulation of response to external stimulus
                                        is-anegative regulation of antimicrobial humoral response
                                        is-anegative regulation of axon regeneration +
                                        is-anegative regulation of chemotaxis +
                                        is-anegative regulation of defense response to bacterium +
                                        is-anegative regulation of defense response to insect
                                        is-anegative regulation of defense response to oomycetes
                                        is-anegative regulation of defense response to virus +
                                        is-anegative regulation of inflammatory response +
                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                        is-anegative regulation of neutrophil mediated killing of symbiont cell +
                                        is-anegative regulation of response to extracellular stimulus +
                                        is-anegative regulation of systemic acquired resistance
                                        is-anegative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                        is-anegative regulation of wound healing +
                                        is-aprepulse inhibition [GO:0060134] (13 genes, 14 annotations)


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-anegative regulation of biological process
                                is-anegative regulation of response to stimulus
                                        is-anegative regulation of response to external stimulus
                                                is-anegative regulation of antimicrobial humoral response
                                                is-anegative regulation of axon regeneration +
                                                is-anegative regulation of chemotaxis +
                                                is-anegative regulation of defense response to bacterium +
                                                is-anegative regulation of defense response to insect
                                                is-anegative regulation of defense response to oomycetes
                                                is-anegative regulation of defense response to virus +
                                                is-anegative regulation of inflammatory response +
                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                is-anegative regulation of neutrophil mediated killing of symbiont cell +
                                                is-anegative regulation of response to extracellular stimulus +
                                                is-anegative regulation of systemic acquired resistance
                                                is-anegative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                is-anegative regulation of wound healing +
                                                is-aprepulse inhibition [GO:0060134] (13 genes, 14 annotations)


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of response to stimulus
                                is-anegative regulation of response to stimulus
                                        is-anegative regulation of response to external stimulus
                                                is-anegative regulation of antimicrobial humoral response
                                                is-anegative regulation of axon regeneration +
                                                is-anegative regulation of chemotaxis +
                                                is-anegative regulation of defense response to bacterium +
                                                is-anegative regulation of defense response to insect
                                                is-anegative regulation of defense response to oomycetes
                                                is-anegative regulation of defense response to virus +
                                                is-anegative regulation of inflammatory response +
                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                is-anegative regulation of neutrophil mediated killing of symbiont cell +
                                                is-anegative regulation of response to extracellular stimulus +
                                                is-anegative regulation of systemic acquired resistance
                                                is-anegative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                is-anegative regulation of wound healing +
                                                is-aprepulse inhibition [GO:0060134] (13 genes, 14 annotations)


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of response to stimulus
                                is-aregulation of response to external stimulus
                                        is-anegative regulation of response to external stimulus
                                                is-anegative regulation of antimicrobial humoral response
                                                is-anegative regulation of axon regeneration +
                                                is-anegative regulation of chemotaxis +
                                                is-anegative regulation of defense response to bacterium +
                                                is-anegative regulation of defense response to insect
                                                is-anegative regulation of defense response to oomycetes
                                                is-anegative regulation of defense response to virus +
                                                is-anegative regulation of inflammatory response +
                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                is-anegative regulation of neutrophil mediated killing of symbiont cell +
                                                is-anegative regulation of response to extracellular stimulus +
                                                is-anegative regulation of systemic acquired resistance
                                                is-anegative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                is-anegative regulation of wound healing +
                                                is-aprepulse inhibition [GO:0060134] (13 genes, 14 annotations)


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        negatively-regulatesnegative regulation of response to stimulus
                                is-anegative regulation of response to external stimulus
                                        is-anegative regulation of antimicrobial humoral response
                                        is-anegative regulation of axon regeneration +
                                        is-anegative regulation of chemotaxis +
                                        is-anegative regulation of defense response to bacterium +
                                        is-anegative regulation of defense response to insect
                                        is-anegative regulation of defense response to oomycetes
                                        is-anegative regulation of defense response to virus +
                                        is-anegative regulation of inflammatory response +
                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                        is-anegative regulation of neutrophil mediated killing of symbiont cell +
                                        is-anegative regulation of response to extracellular stimulus +
                                        is-anegative regulation of systemic acquired resistance
                                        is-anegative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                        is-anegative regulation of wound healing +
                                        is-aprepulse inhibition [GO:0060134] (13 genes, 14 annotations)


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        regulatesregulation of response to stimulus
                                is-anegative regulation of response to stimulus
                                        is-anegative regulation of response to external stimulus
                                                is-anegative regulation of antimicrobial humoral response
                                                is-anegative regulation of axon regeneration +
                                                is-anegative regulation of chemotaxis +
                                                is-anegative regulation of defense response to bacterium +
                                                is-anegative regulation of defense response to insect
                                                is-anegative regulation of defense response to oomycetes
                                                is-anegative regulation of defense response to virus +
                                                is-anegative regulation of inflammatory response +
                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                is-anegative regulation of neutrophil mediated killing of symbiont cell +
                                                is-anegative regulation of response to extracellular stimulus +
                                                is-anegative regulation of systemic acquired resistance
                                                is-anegative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                is-anegative regulation of wound healing +
                                                is-aprepulse inhibition [GO:0060134] (13 genes, 14 annotations)


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        regulatesregulation of response to stimulus
                                is-aregulation of response to external stimulus
                                        is-anegative regulation of response to external stimulus
                                                is-anegative regulation of antimicrobial humoral response
                                                is-anegative regulation of axon regeneration +
                                                is-anegative regulation of chemotaxis +
                                                is-anegative regulation of defense response to bacterium +
                                                is-anegative regulation of defense response to insect
                                                is-anegative regulation of defense response to oomycetes
                                                is-anegative regulation of defense response to virus +
                                                is-anegative regulation of inflammatory response +
                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                is-anegative regulation of neutrophil mediated killing of symbiont cell +
                                                is-anegative regulation of response to extracellular stimulus +
                                                is-anegative regulation of systemic acquired resistance
                                                is-anegative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                is-anegative regulation of wound healing +
                                                is-aprepulse inhibition [GO:0060134] (13 genes, 14 annotations)


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to external stimulus
                                negatively-regulatesnegative regulation of response to external stimulus
                                        is-anegative regulation of antimicrobial humoral response
                                        is-anegative regulation of axon regeneration +
                                        is-anegative regulation of chemotaxis +
                                        is-anegative regulation of defense response to bacterium +
                                        is-anegative regulation of defense response to insect
                                        is-anegative regulation of defense response to oomycetes
                                        is-anegative regulation of defense response to virus +
                                        is-anegative regulation of inflammatory response +
                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                        is-anegative regulation of neutrophil mediated killing of symbiont cell +
                                        is-anegative regulation of response to extracellular stimulus +
                                        is-anegative regulation of systemic acquired resistance
                                        is-anegative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                        is-anegative regulation of wound healing +
                                        is-aprepulse inhibition [GO:0060134] (13 genes, 14 annotations)


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to external stimulus
                                regulatesregulation of response to external stimulus
                                        is-anegative regulation of response to external stimulus
                                                is-anegative regulation of antimicrobial humoral response
                                                is-anegative regulation of axon regeneration +
                                                is-anegative regulation of chemotaxis +
                                                is-anegative regulation of defense response to bacterium +
                                                is-anegative regulation of defense response to insect
                                                is-anegative regulation of defense response to oomycetes
                                                is-anegative regulation of defense response to virus +
                                                is-anegative regulation of inflammatory response +
                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                is-anegative regulation of neutrophil mediated killing of symbiont cell +
                                                is-anegative regulation of response to extracellular stimulus +
                                                is-anegative regulation of systemic acquired resistance
                                                is-anegative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                is-anegative regulation of wound healing +
                                                is-aprepulse inhibition [GO:0060134] (13 genes, 14 annotations)


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to external stimulus
                                is-astartle response
                                        part-ofprepulse inhibition [GO:0060134] (13 genes, 14 annotations)


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-asystem process
                                        is-aneurological system process
                                                is-aneuromuscular process
                                                        is-astartle response
                                                                part-ofprepulse inhibition [GO:0060134] (13 genes, 14 annotations)


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory