Excel File Text File *Disease is associated/modeled with this Gene or a homolog. More...
      Disease Term Human Homologs Mouse Homologs Mouse Models Homology Source
     acute myeloid leukemia ASXL1* Asxl1* 1 model Alliance of Genome Resources
acute myeloid leukemia CEBPA* Cebpa* 1 model Alliance of Genome Resources
acute myeloid leukemia CREBBP* Crebbp* 1 model Alliance of Genome Resources
acute myeloid leukemia FLT3* Flt3* 4 models Alliance of Genome Resources
acute myeloid leukemia KMT2A* Kmt2a* 4 models Alliance of Genome Resources
     acute myeloid leukemia ARID4A Arid4a* 2 models Alliance of Genome Resources
acute myeloid leukemia MYBL2 Mybl2* 1 model Alliance of Genome Resources
acute myeloid leukemia SPI1 Spi1* 1 model Alliance of Genome Resources
chronic myeloid leukemia CHORDC1 Chordc1* 1 model Alliance of Genome Resources
chronic myeloid leukemia NCSTN Ncstn* 2 models Alliance of Genome Resources
chronic myeloid leukemia SH2B3 Sh2b3* 1 model Alliance of Genome Resources
chronic myeloid leukemia SIPA1 Sipa1* 2 models Alliance of Genome Resources
familial chronic myelocytic leukemia-like syndrome IRF8 Irf8* 4 models Alliance of Genome Resources
     acute megakaryocytic leukemia EZH2* Ezh2   Alliance of Genome Resources
acute megakaryocytic leukemia MRTFA* Mrtfa   Alliance of Genome Resources
acute megakaryocytic leukemia JAK3* Jak3   Alliance of Genome Resources
acute monocytic leukemia MLLT10* Mllt10   Alliance of Genome Resources
acute myeloid leukemia ZRSR2*, ZRSR2P1 Zrsr2, Zrsr2-ps1   Alliance of Genome Resources
acute myeloid leukemia EPHX1* Ephx1   Alliance of Genome Resources
acute myeloid leukemia ERCC1* Ercc1   Alliance of Genome Resources
acute myeloid leukemia ERCC2* Ercc2   Alliance of Genome Resources
acute myeloid leukemia ETV6* Etv6   Alliance of Genome Resources
acute myeloid leukemia EZH2* Ezh2   Alliance of Genome Resources
acute myeloid leukemia FANCA* Fanca   Alliance of Genome Resources
acute myeloid leukemia FANCC* Fancc   Alliance of Genome Resources
acute myeloid leukemia FAS* Fas   Alliance of Genome Resources
acute myeloid leukemia FGFR1* Fgfr1   Alliance of Genome Resources
acute myeloid leukemia GATA2* Gata2   Alliance of Genome Resources
acute myeloid leukemia GFI1* Gfi1   Alliance of Genome Resources
acute myeloid leukemia GPX1* Gpx1   Alliance of Genome Resources
acute myeloid leukemia GSTM1*, GSTM5 Gstm1, Gstm2, Gstm3, Gstm6   Alliance of Genome Resources
acute myeloid leukemia GSTP1* Gstp1, Gstp2, Gstp3   Alliance of Genome Resources
acute myeloid leukemia GSTT1* Gstt1   Alliance of Genome Resources
acute myeloid leukemia HLA-DQB1*, HLA-DQB2 H2-Ab1   Alliance of Genome Resources
acute myeloid leukemia IDH1* Idh1   Alliance of Genome Resources
acute myeloid leukemia IDH2* Idh2   Alliance of Genome Resources
acute myeloid leukemia IL1A* Il1a   Alliance of Genome Resources
acute myeloid leukemia IL6* Il6   Alliance of Genome Resources
acute myeloid leukemia ITGAV* Itgav   Alliance of Genome Resources
acute myeloid leukemia ITGB3* Itgb3   Alliance of Genome Resources
acute myeloid leukemia JAK2* Jak2   Alliance of Genome Resources
acute myeloid leukemia KAT6A* Kat6a   Alliance of Genome Resources
acute myeloid leukemia KIT* Kit   Alliance of Genome Resources
acute myeloid leukemia KRAS* Kras 1 "NOT" model Alliance of Genome Resources
acute myeloid leukemia LPP* Lpp   Alliance of Genome Resources
acute myeloid leukemia MEFV* Mefv   Alliance of Genome Resources
acute myeloid leukemia MLLT10* Mllt10   Alliance of Genome Resources
acute myeloid leukemia MTHFR* Mthfr   Alliance of Genome Resources
acute myeloid leukemia MTRR* Mtrr   Alliance of Genome Resources
acute myeloid leukemia NAT2*, NAT1 Nat1, Nat2, Nat3   Alliance of Genome Resources
acute myeloid leukemia NCOA2* Ncoa2   Alliance of Genome Resources
acute myeloid leukemia NF1* Nf1   Alliance of Genome Resources
acute myeloid leukemia NOS3* Nos3   Alliance of Genome Resources
acute myeloid leukemia NPM1* Npm1 1 "NOT" model Alliance of Genome Resources
acute myeloid leukemia NQO1* Nqo1   Alliance of Genome Resources
acute myeloid leukemia NRAS* Nras   Alliance of Genome Resources
acute myeloid leukemia NSD1* Nsd1   Alliance of Genome Resources
acute myeloid leukemia NUP214* Nup214   Alliance of Genome Resources
acute myeloid leukemia PHF6* Phf6   Alliance of Genome Resources
acute myeloid leukemia PICALM* Picalm   Alliance of Genome Resources
acute myeloid leukemia RUNX1* Runx1   Alliance of Genome Resources
acute myeloid leukemia SAMHD1* Samhd1   Alliance of Genome Resources
acute myeloid leukemia SH3GL1* Sh3gl1   Alliance of Genome Resources
acute myeloid leukemia SOCS1* Socs1   Alliance of Genome Resources
acute myeloid leukemia SOD2* Sod2   Alliance of Genome Resources
acute myeloid leukemia SRSF2* Srsf2   Alliance of Genome Resources
acute myeloid leukemia TERT* Tert   Alliance of Genome Resources
acute myeloid leukemia TET2* Tet2   Alliance of Genome Resources
acute myeloid leukemia TFPI2* Tfpi2   Alliance of Genome Resources
acute myeloid leukemia TP53* Trp53   Alliance of Genome Resources
acute myeloid leukemia TYMS* Tyms   Alliance of Genome Resources
acute myeloid leukemia VEGFA* Vegfa   Alliance of Genome Resources
acute myeloid leukemia ABL1* Abl1   Alliance of Genome Resources
acute myeloid leukemia ACSL6* Acsl6   Alliance of Genome Resources
acute myeloid leukemia BCL2* Bcl2   Alliance of Genome Resources
acute myeloid leukemia BMI1*, COMMD3-BMI1 Bmi1   Alliance of Genome Resources
acute myeloid leukemia BRD7* Brd7   Alliance of Genome Resources
acute myeloid leukemia CBL* Cbl   Alliance of Genome Resources
acute myeloid leukemia CCND1* Ccnd1   Alliance of Genome Resources
acute myeloid leukemia CDH1* Cdh1   Alliance of Genome Resources
acute myeloid leukemia CDKN1B* Cdkn1b   Alliance of Genome Resources
acute myeloid leukemia CDKN2A*, CDKN2B* Cdkn2a, Cdkn2b   Alliance of Genome Resources
acute myeloid leukemia CFHR1*, CFHR2 Cfhr1   Alliance of Genome Resources
acute myeloid leukemia CHIC2* Chic2   Alliance of Genome Resources
acute myeloid leukemia CSF2* Csf2   Alliance of Genome Resources
acute myeloid leukemia CSF3* Csf3   Alliance of Genome Resources
acute myeloid leukemia CSF3R* Csf3r   Alliance of Genome Resources
acute myeloid leukemia CTLA4* Ctla4   Alliance of Genome Resources
acute myeloid leukemia CXCR4* Cxcr4   Alliance of Genome Resources
acute myeloid leukemia CYP1A1* Cyp1a1   Alliance of Genome Resources
acute myeloid leukemia CYP2B6* Cyp2b9, Cyp2b10, Cyp2b13, Cyp2b19, Cyp2b23   Alliance of Genome Resources
acute myeloid leukemia CYP2D6*, CYP2D7 Cyp2d9, Cyp2d10, Cyp2d11, Cyp2d12, Cyp2d22, Cyp2d26, Cyp2d34, Cyp2d40   Alliance of Genome Resources
acute myeloid leukemia DLEC1* Dlec1   Alliance of Genome Resources
acute myeloid leukemia DNMT3A* Dnmt3a   Alliance of Genome Resources
acute myeloid leukemia DNMT3B* Dnmt3b   Alliance of Genome Resources
acute myelomonocytic leukemia GMPS* Gmps   Alliance of Genome Resources
acute myelomonocytic leukemia FLT3* Flt3   Alliance of Genome Resources
acute myelomonocytic leukemia CBFB* Cbfb   Alliance of Genome Resources
acute myelomonocytic leukemia ARHGAP26* Arhgap26   Alliance of Genome Resources
acute promyelocytic leukemia GSTT1* Gstt1   Alliance of Genome Resources
acute promyelocytic leukemia MYC* Myc   Alliance of Genome Resources
acute promyelocytic leukemia PML* Pml 1 model Alliance of Genome Resources
acute promyelocytic leukemia ZBTB16* Zbtb16 1 model Alliance of Genome Resources
acute promyelocytic leukemia RARA* Rara   Alliance of Genome Resources
acute promyelocytic leukemia CDKN2B*, CDKN2A Cdkn2a, Cdkn2b   Alliance of Genome Resources
chronic myeloid leukemia HLA-DQA1*, HLA-DQA2 H2-Aa   Alliance of Genome Resources
chronic myeloid leukemia HLA-DQB1*, HLA-DQB2 H2-Ab1   Alliance of Genome Resources
chronic myeloid leukemia MDM2* Mdm2   Alliance of Genome Resources
chronic myeloid leukemia MTHFR* Mthfr   Alliance of Genome Resources
chronic myeloid leukemia NQO1* Nqo1   Alliance of Genome Resources
chronic myeloid leukemia VEGFA* Vegfa   Alliance of Genome Resources
chronic myeloid leukemia XRCC1* Xrcc1   Alliance of Genome Resources
chronic myeloid leukemia IL10* Il10   Alliance of Genome Resources
chronic myeloid leukemia ABCB1* Abcb1a, Abcb1b   Alliance of Genome Resources
chronic myeloid leukemia ABCC2* Abcc2   Alliance of Genome Resources
chronic myeloid leukemia ABCG2* Abcg2, Abcg3   Alliance of Genome Resources
chronic myeloid leukemia ABL1* Abl1   Alliance of Genome Resources
chronic myeloid leukemia AKT1* Akt1   Alliance of Genome Resources
chronic myeloid leukemia BCL2L1* Bcl2l1   Alliance of Genome Resources
chronic myeloid leukemia BCR* Bcr   Alliance of Genome Resources
chronic myeloid leukemia CRKL* Crkl   Alliance of Genome Resources
chronic myeloid leukemia CYP1A1* Cyp1a1   Alliance of Genome Resources
chronic myeloid leukemia CYP3A5*, CYP3A4, CYP3A7, CYP3A7-CYP3A51P, CYP3A43 Cyp3a11, Cyp3a13, Cyp3a16, Cyp3a25, Cyp3a41a, Cyp3a41b, Cyp3a44, Cyp3a57, Cyp3a59   Alliance of Genome Resources
chronic myeloid leukemia ERCC2* Ercc2   Alliance of Genome Resources
chronic myeloid leukemia FAS* Fas   Alliance of Genome Resources
chronic myeloid leukemia FASLG* Fasl   Alliance of Genome Resources
myeloid leukemia PDGFRA* Pdgfra   Alliance of Genome Resources
myeloid leukemia NSD3* Nsd3   Alliance of Genome Resources
myeloid leukemia MN1* Mn1   Alliance of Genome Resources
myeloid leukemia IFNG* Ifng   Alliance of Genome Resources
myeloid leukemia FGFR1* Fgfr1   Alliance of Genome Resources
myeloid leukemia ERG* Erg   Alliance of Genome Resources
myeloid leukemia CBX7* Cbx7   Alliance of Genome Resources
myeloid leukemia GSTM1*, GSTM5 Gstm1, Gstm2, Gstm3, Gstm6   Alliance of Genome Resources
myeloid leukemia GATA2* Gata2   Alliance of Genome Resources
myeloid leukemia UGT1A1* Ugt1a1   Alliance of Genome Resources
myeloid leukemia PRAME*, PRAMEF1, PRAMEF2, PRAMEF4, PRAMEF5, PRAMEF6, PRAMEF7, PRAMEF8, PRAMEF10, PRAMEF11, PRAMEF12, PRAMEF13, PRAMEF14, PRAMEF15, PRAMEF17, PRAMEF18, PRAMEF19, PRAMEF20, PRAMEF22, PRAMEF25, PRAMEF26, PRAMEF27, PRAMEF33 Gm13040, Gm13043, Pramel5, Pramel11, Pramel12, Pramel13, Pramel15, Pramel16, Pramel19, Pramel20, Pramel21, Pramel24, Pramel28, Pramel30, Pramel31, Pramel32, Pramel34, Pramel35, Pramel36, Pramel37, Pramel38, Pramel40, Pramel41, Pramel42, Pramel43, Pramel44, Pramel46, Pramel47, Pramel48, Pramel49, Pramel50, Pramel53, Pramel54, Pramel55, Pramel56, Pramel57, Pramel60, Pramel61   Alliance of Genome Resources
myeloid leukemia GSTT1* Gstt1   Alliance of Genome Resources
myeloid leukemia GSTP1* Gstp1, Gstp2, Gstp3   Alliance of Genome Resources
myeloid leukemia associated with Down Syndrome GATA1* Gata1   Alliance of Genome Resources

 
Transgenes and other genome features developed in mice to model this disease.
     Disease Term Transgenes and Other Genome Features Mouse Models
  acute myeloid leukemia Tg(CMV-SALL4_iB)#Chai 1 model
  acute myeloid leukemia Tg(Vav1-Asxl1*Y588X)#Fcy 1 model
  acute myeloid leukemia Tg(Vav1-ERG)#Jpim 1 model
  acute promyelocytic leukemia Tg(PML-RARA)556Kog 2 models
  acute promyelocytic leukemia Tg(CTSG-NUMA1/RARA)#Skr 1 model
  chronic myeloid leukemia Tg(Ly6a-TK,-BCR/ABL1)IS9AIsg 1 model
  chronic myeloid leukemia Tg(tetO-BCR/ABL1)2Dgt 2 models
  chronic myeloid leukemia Tg(Ly6a-BCR/ABL1)IS1AIsg 1 model
  chronic myeloid leukemia Tg(Ly6a-BCR/ABL1)IS1BIsg 1 model