Pramel55 Gene Detail

Summary

• Symbol
  Pramel55
• Name
  PRAME like 55
• Synonyms
  E330014E10Rik

• Feature Type
  protein coding gene
• IDs
  MGI:3615333
  NCBI Gene: 665943
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr5:95923729-95952089 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, 47.29 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  17 from dbSNP Build 142
• Strain Annotations
  16

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3615333	protein coding gene	Chr5:95923729-95952089 (+)
129S1/SvImJ	ENSMUSG00200008996	protein coding gene	Chr5:89600704-89629484 (+)
A/J	ENSMUSG00195024225	protein coding gene	Chr5:89200351-89203412 (+)
AKR/J	ENSMUSG00220011530	protein coding gene	Chr5:88663724-88666793 (+)
BALB/cJ	ENSMUSG00180020882	protein coding gene	Chr5:89369365-89372431 (+)
C3H/HeJ	ENSMUSG00175043466	protein coding gene	Chr5:91472460-91475523 (+)
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	ENSMUSG00210005394	protein coding gene	Chr5:90212300-90248119 (+)
DBA/2J	ENSMUSG00185036117	protein coding gene	Chr5:93128351-93164167 (+)
DBA/2J	ENSMUSG00185036755	protein coding gene	Chr5:92871041-92875326 (+)
FVB/NJ	ENSMUSG00205025712	protein coding gene	Chr5:88778181-88790378 (+)
JF1/MsJ	no annotation
LP/J	ENSMUSG00230026964	protein coding gene	Chr5:96931409-96934467 (+)
LP/J	ENSMUSG00230025482	protein coding gene	Chr5:97181583-97210280 (+)
NOD/ShiLtJ	ENSMUSG00190036850	protein coding gene	Chr5:89111025-89139799 (+)
NZO/HlLtJ	ENSMUSG00225012262	protein coding gene	Chr5:104925594-104954313 (+)
NZO/HlLtJ	ENSMUSG00225012624	protein coding gene	Chr5:103453603-103482304 (+)
NZO/HlLtJ	ENSMUSG00225012313	protein coding gene	Chr5:104660359-104672554 (+)
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Homology

• Human Ortholog
  PRAMEF15, PRAME family member 15

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  PRAMEF15, PRAME family member 15
  
• Links
  HGNC:26764

  NCBI Gene ID: 653619

  UniProt: P0DUQ1

  
  
• Chr Location
  1p36.21; chr1:13315581-13322598 (+)  GRCh38

---

• Human Ortholog
  PRAMEF20, PRAME family member 20
  
• Synonyms
  PRAMEF21
• Links
  HGNC:25224

  NCBI Gene ID: 645425

  UniProt: Q5VT98

  
  
• Chr Location
  1p36.21; chr1:13410450-13421328 (+)  GRCh38

---

• Human Ortholog
  PRAMEF4, PRAME family member 4
  
• Links
  HGNC:31971

  NCBI Gene ID: 400735

  UniProt: O60810

  
  
• Chr Location
  1p36.21; chr1:12879212-12886201 (-)  GRCh38

---

• MGI Vertebrate Homology
  Pramel55 stringent orthology
  3 human;1 mouse
  
• HCOP
  vertebrate homology predictions: PRAMEF15, PRAMEF20, PRAMEF4
• Protein SuperFamily
  PRAME
• Gene Tree
  Pramel55
  

Human Diseases

• Diseases
  1 with human PRAME associations

				Human Disease	Mouse Models
				myeloid leukemia IDs myeloid leukemia       DOID:8692 DOID:8878 DOID:8879 DOID:8910 DOID:9066 DOID:9126 ICD10CM:C92 ICD9CM:205 ICD9CM:205.9 MESH:D007951 NCI:C3172 UMLS_CUI:C0023470

Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  6 phenotype references
  

• All Mutations and Alleles
  3
• Chemically induced (other)
  1
• Radiation induced
  1
• Spontaneous
  1
• Genomic Mutations
  3 involving Pramel55
• Find Mice (IMSR)
  4 strains or lines available

Expression

• Assay Results
  597
• cDNA Data
  1

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  24
• RefSeq
  2
• CCDS
  CCDS51565.1

• Ensembl
  ENSMUSG00000072813 (Evidence)
• NCBI Gene
  665943

Representative Sequences			Length	Strain/Species
genomic	665943	NCBI Gene Model | MGI Sequence Detail	28361	C57BL/6J
transcript	NM_001122668	RefSeq | MGI Sequence Detail	2118	C57BL/6
polypeptide	NP_001116140	RefSeq | MGI Sequence Detail	481	C57BL/6

Molecular
Reagents

• All nucleic 1

  cDNA 1

  
  

  Microarray probesets 5

Other
Accession IDs

MGI:7466587

References

• Summaries
  All 15

  Phenotypes 6
• Earliest
  J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
• Latest
  J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17