Excel File Text File All mouse models of osteochondrodysplasia with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      acheiropody Lmbr1tm1Kng/Lmbr1tm1Kng involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J J:72166 View
achondrogenesis type IA Trip11m1Mawa/Trip11m1Mawa C57BL/6J-Trip11m1Mawa J:163656 View
achondrogenesis type IA Tg(EIIa-cre)C5379Lmgd/?
Trip11tm1.2Psmi/Trip11tm1.2Psmi
involves: 129/Sv * C57BL/6 * FVB/N J:253969 View
achondrogenesis type IA Trip11tm1.1Psmi/Trip11tm1.2Psmi
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/?
Tg(Col2a1-cre)1Bhr/?
involves: 129/Sv * C57BL/6 * SJL/J J:253969 View
achondrogenesis type II Col2a1tm1Prc/Col2a1tm1Prc involves: 129 J:117910 View
achondroplasia Tg(Col2a1-Fgfr3/GH)BDor/0 FVB/N-Tg(Col2a1-Fgfr3/GH)BDor J:50292 View
achondroplasia Fgfr3tm2Wei/Fgfr3+ involves: 129S1/Sv * 129X1/SvJ * MF1 J:54829 View
achondroplasia Fgfr3tm1Llm/Fgfr3+ involves: 129S2/SvPas J:203653 View
achondroplasia Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd involves: 129S6/SvEvTac J:69849 View
achondroplasia Fgfr3tm3.1Cxd/Fgfr3+ involves: 129S6/SvEvTac J:69849 View
achondroplasia Fgfr3tm5.1Cxd/Fgfr3+ involves: 129S6/SvEvTac J:67780 View
achondroplasia Fgfr3tm1Cxd/Fgfr3tm1Cxd involves: 129S6/SvEvTac * NIH Black Swiss J:52438 View
acromesomelic dysplasia, Grebe type Gdf5Bp-5J/Gdf5+ C57BL/6J-Gdf5Bp-5J/GrsrJ J:200816 View
acromesomelic dysplasia, Grebe type Gdf5bp-J/Gdf5bp-J
Gdf6tm1Kng/Gdf6tm1Kng
involves: 129S1/Sv * 129X1/SvJ * A/J * C57BL/6J J:83132 View
acromesomelic dysplasia, Hunter-Thompson type Gdf5Bp-5J/Gdf5+ C57BL/6J-Gdf5Bp-5J/GrsrJ J:200816 View
acromesomelic dysplasia, Maroteaux type Npr2pwe/Npr2pwe involves: C3H/HeJ * C57BL/6 * NAW/WI J:188839 View
acromesomelic dysplasia, Maroteaux type Npr2slw/Npr2slw involves: C57BL/6 * DDY J:129973 View
campomelic dysplasia Sox9Bbfc/Sox9+ C57BL/6J-Sox9Bbfc/GrsrJ J:223062 View
campomelic dysplasia Sox9tm1.1Gsr/Sox9+ involves: 129P2/OlaHsd * C57BL/6 J:75124 View
campomelic dysplasia Sox9tm1Gsr/Sox9+
Tg(Pdx1-cre)6Cvw/0
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA * FVB/N J:141017 View
campomelic dysplasia Sox9tm1Crm/Sox9+ involves: 129S7/SvEvBrd * C57BL/6 * CD-1 J:69875 View
campomelic dysplasia Sox9tm2Crm/Sox9tm2Crm
Tg(Col2a1-cre)1Bhr/0
involves: 129S/SvEv * C57BL/6 * SJL J:79879 View
campomelic dysplasia Sox9tm2Crm/Sox9+
Tg(Col2a1-cre)1Bhr/0
involves: 129S/SvEv * C57BL/6 * SJL J:79879 View
campomelic dysplasia Sox9tm2Crm/Sox9tm2Crm
Tg(Prrx1-cre)1Cjt/0
involves: 129S/SvEv * C57BL/6J * SJL/J J:79879 View
campomelic dysplasia Sox9tm2Crm/Sox9+
Tg(Prrx1-cre)1Cjt/0
involves: 129S/SvEv * C57BL/6J * SJL/J J:79879 View
cleidocranial dysplasia Runx2tm1Kish/Runx2tm1Kish involves: 129P2/OlaHsd * C57BL/6 J:40783, J:53069, J:54095 View
cleidocranial dysplasia Runx2tm1Kish/Runx2+ involves: 129P2/OlaHsd * C57BL/6 J:40783 View
cleidocranial dysplasia Runx2tm1Mjo/Runx2+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:40784, J:53868 View
cleidocranial dysplasia Runx2tm1Jals/Runx2tm1Jals involves: 129S7/SvEvBrd * C57BL/6 J:143532 View
diastrophic dysplasia Slc26a2tm1Aros/Slc26a2tm1Aros involves: 129S7/SvEvBrd * C57BL/6J J:97104 View
hypertrichotic osteochondrodysplasia Cantu type Abcc9em1Nich/Abcc9em1Nich involves: C57BL/6J * CBA/J J:281903 View
hypertrichotic osteochondrodysplasia Cantu type Abcc9em1Nich/Abcc9+ involves: C57BL/6J * CBA/J J:281903 View
microcephalic osteodysplastic primordial dwarfism type II PcntGt(RRU388)Byg/PcntGt(RRU388)Byg B6.129P2-PcntGt(RRU388)Byg J:226309 View
multiple epiphyseal dysplasia 5 Matn3tm1Mbri/Matn3tm1Mbri involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:125104 View
osteogenesis imperfecta type 1 Col1a1Mov13/Col1a1+ involves: C57BL/6 J:107045 View
osteogenesis imperfecta type 1 Tg(COL1A1)73Prc/0 involves: FVB/N J:146429 View
osteogenesis imperfecta type 2 Col1a1tm1Jcm/Col1a1+ either: (involves: 129X1/SvJ * C3H/HeJ) or (involves: 129X1/SvJ * CD-1) J:59168 View
osteogenesis imperfecta type 2 Col1a1Aga2/Col1a1+ involves: C3HeB/FeJ * C57BL/6J J:129569 View
osteogenesis imperfecta type 3 Col1a2oim/Col1a2oim B6C3Fe a/a-Col1a2oim/J J:38013 View
osteogenesis imperfecta type 3 Col1a1Aga2/Col1a1+ C3HeB/FeJ-Col1a1Aga2 J:185988 View
osteogenesis imperfecta type 3 Col1a2oim/Col1a2oim involves: C3H/HeJ * C57BL/6JLe J:4348 View
osteogenesis imperfecta type 4 Col1a1tm1.1Jcm/Col1a1+ either: (involves: 129X1/SvJ * C3H/HeJ) or (involves: 129X1/SvJ * CD-1) J:59168 View
osteogenesis imperfecta type 4 Col1a1M1Jrt/Col1a1+ involves: C3H/HeJ * C57BL/6J * FVB/NJ J:216423 View
osteogenesis imperfecta type 4 Col1a1M1Jrt/Col1a1+ involves: C57BL/6 * FVB/N J:228439 View
osteogenesis imperfecta type 6 Serpinf1tm1Craw/Serpinf1tm1Craw Not Specified J:230409 View
osteogenesis imperfecta type 7 Crtaptm1Brle/Crtaptm1Brle involves: 129S7/SvEvBrd J:116096 View
osteogenesis imperfecta type 8 P3h1tm1Dgen/P3h1tm1Dgen involves: C57BL/6 J:163884 View
osteogenesis imperfecta type 9 PpibGt(RST139)Byg/PpibGt(RST139)Byg involves: 129P2/OlaHsd * C57BL/6 J:226318 View
osteogenesis imperfecta type 9 Ppibtm1.1Rjb/Ppibtm1.1Rjb Not Specified J:161748 View
osteogenesis imperfecta type 10 Serpinh1tm2Kzn/Serpinh1tm2Kzn
Tg(Col2a1-cre)1Bhr/0
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL J:197791 View
otospondylomegaepiphyseal dysplasia Col11a2tm1Mne/Col11a2tm1Mne FVB.129-Col11a2tm1Mne J:71948 View
progressive pseudorheumatoid arthropathy of childhood Ccn6tm2Mawa/Ccn6tm2Mawa 129S/SvEv-Ccn6tm2Mawa J:94500 View
progressive pseudorheumatoid arthropathy of childhood Ccn6tm1(cre)Mawa/Ccn6tm1(cre)Mawa involves: 129S4/SvJae * C57BL/6 J:201718 View
progressive pseudorheumatoid arthropathy of childhood Ccn6tm2Mawa/Ccn6tm2Mawa involves: 129S/SvEv * C57BL/6 J:201718 View
pseudoachondroplasia Tg(Col2a1-rtTA,tetO-COMP*)2Jath/0 C57BL/6-Tg(Col2a1-rtTA,tetO-COMP*)2Jath J:152756, J:233238 View
pseudoachondroplasia Comptm2.1Mbri/Comptm2.1Mbri involves: 129S1/Sv * 129X1/SvJ J:206511 View
pseudoachondroplasia Comptm1Mbri/Comptm1Mbri involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:125086 View
Schimke immuno-osseous dysplasia Smarcal1tm1.1Cfbo/Smarcal1tm1.1Cfbo either: B6.129-Smarcal1tm1.1Cfbo or (involves: 129 * C57BL/6) J:183899 View
Schmid metaphyseal chondrodysplasia Col10a1tm1.1Rpbh/Col10a1tm1.1Rpbh involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:154052 View
Schmid metaphyseal chondrodysplasia Col10a1tm2.1Rpbh/Col10a1tm2.1Rpbh involves: C57BL/6NTac J:267200 View
Schmid metaphyseal chondrodysplasia Col10a1tm2.1Rpbh/Col10a1+ involves: C57BL/6NTac J:267200 View
schneckenbecken dysplasia Slc35d1tm1Hko/Slc35d1tm1Hko involves: 129S1/Sv * 129X1/SvJ J:130304 View
Silverman-Handmaker type dyssegmental dysplasia Hspg2tm1Ref/Hspg2tm1Ref involves: 129S1/Sv * 129X1/SvJ J:84739 View
Silverman-Handmaker type dyssegmental dysplasia Hspg2tm1Nid/Hspg2tm1Nid involves: 129X1/SvJ * C57BL/6 J:74542 View
Smith-McCort dysplasia DymGt(GTR1.3)1Rul/DymGt(GTR1.3)1Rul involves: 129 J:141099 View
spondyloepimetaphyseal dysplasia, Pakistani type Papss2bm/Papss2bm LDJ/Le J:5109 View
spondyloepiphyseal dysplasia congenita Col2a1M3J/Col2a1+ B6(Cg)-Col2a1M3J/GrsrJ J:222308 View
spondyloepiphyseal dysplasia congenita Col2a1M2J/Col2a1+ B6;C3Fe-Col2a1M2J/GrsrJ J:222308 View
spondyloepiphyseal dysplasia congenita Col2a1Lpk/Col2a1+ C.B6(C3)-Col2a1Lpk J:187141 View
spondyloepiphyseal dysplasia congenita Col2a1tm1Prc/Col2a1tm1Prc involves: 129/Sv * C57BL/6 J:30041 View
spondyloepiphyseal dysplasia congenita Gt(ROSA)26Sortm5(ACTB-tTA)Luo/Gt(ROSA)26Sor+
Tg(Col2a1-cre)1Bhr/0
Tg(tetO/CMV-Col2a1*R992C,-GFP)#Afe/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL J:216945 View
spondyloepiphyseal dysplasia congenita Col2a1Lpk/Col2a1+ involves: C3H/HeH * C57BL/6J J:187141 View
spondyloepiphyseal dysplasia congenita Tg(Col2a1*R789C)#Waho/0 involves: C57BL/6 * DBA/2 J:112540 View
spondyloepiphyseal dysplasia congenita Col2a1sedc/Col2a1sedc involves: C57BL/6J J:85735 View
thanatophoric dysplasia Fgfr3tm1Llm/Fgfr3+ involves: 129S2/SvPas * C57BL/6J J:147208 View
thanatophoric dysplasia Fgfr3tm5.1Cxd/Fgfr3+ involves: 129S6/SvEvTac J:67780 View
thanatophoric dysplasia Fgfr3tm4Cxd/Fgfr3+
Tg(Col2a1-cre)1Bhr/0
involves: 129S6/SvEvTac * C57BL/6 * NIH Black Swiss * SJL J:63198 View
thanatophoric dysplasia Fgfr3tm4.1Cxd/Fgfr3+ involves: 129S6/SvEvTac * NIH Black Swiss J:63198 View
      achondroplasia Npr2cn-2J/Npr2cn-2J B6;CBACa-Aw-J/A-Kcnj6wv/+ J:72465 View
achondroplasia Pthlhtm1Hmk/Pthlhtm1Hmk either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6) J:16911 View
achondroplasia Spred2Gt(XB228)Byg/Spred2Gt(XB228)Byg involves: 129P2/OlaHsd * C57BL/6 J:100826 View
achondroplasia Npr2cn/Npr2cn involves: AKR/J J:26341 View
achondroplasia Acancmd/Acancmd involves: STOCK T tlow Itpr3tf J:5952, J:30795 View
achondroplasia Npr2cn-3J/Npr2cn-3J MRL/MpJ-Npr2cn-3J/GrsrJ J:170669 View
cleidocranial dysplasia Ccd/Ccd+ B10Rl.101-Ccd J:16170 View
cleidocranial dysplasia Ccd/Ccd+ involves: 101 * C3H J:14006 View
cleidocranial dysplasia Cebpbtm1Kish/Cebpbtm1Kish involves: 129P2/OlaHsd J:237461 View
cleidocranial dysplasia Rnf146tm1.1Rtpl/Rnf146tm1.1Rtpl
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
involves: C57BL/6J * CD-1 J:244583 View
hypertrichotic osteochondrodysplasia Cantu type Kcnj8em1Nich/Kcnj8+ involves: C57BL/6J * CBA/J J:281903 View
Leri-Weill dyschondrosteosis Shox2tm1Ddu/Shox2tm1.1Ddu
Tg(Prrx1-cre)1Cjt/0
involves: 129S2/SvPas * C57BL/6J * SJL/J J:107668 View
multiple epiphyseal dysplasia Comptm1Mbri/Comptm1Mbri involves: 129S1/Sv * 129X1/SvJ J:154984 View
osteochondrodysplasia Atf2tm1Glm/Atf2tm1Glm involves: 129S2/SvPas J:30611 View
osteogenesis imperfecta Col1a2tm1.1Mcbr/Col1a2+ (A/J x B6.129-Col1a2tm1.1Mcbr)F1 J:178743 View
osteogenesis imperfecta Col1a2tm1.1Mcbr/Col1a2+ (BALB/cByJ x B6.129-Col1a2tm1.1Mcbr)F1 J:178743 View
osteogenesis imperfecta Col1a2tm1.1Mcbr/Col1a2+ (C3H/HeJ x B6.129-Col1a2tm1.1Mcbr)F1 J:178743 View
osteogenesis imperfecta Col1a2tm1.1Mcbr/Col1a2+ (FVB/NJ x B6.129-Col1a2tm1.1Mcbr)F1 J:178743 View
osteogenesis imperfecta Col1a2oim/Col1a2+ B6C3Fe a/a-Col1a2oim/J J:38013 View
osteogenesis imperfecta Col1a1m1Btlr/Col1a1m1Btlr C57BL/6J-Col1a1m1Btlr J:253622 View
osteogenesis imperfecta Smad4tm2.1Cxd/Smad4tm2.1Cxd
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
involves: 129S6/SvEvTac * C57BL/6J * CD-1 J:211171 View
osteogenesis imperfecta Smpd3fro/Smpd3fro Not Specified J:100158 View
osteogenesis imperfecta type 2 Smpd3fro/Smpd3fro Not Specified J:3906 View
osteogenesis imperfecta type 3 Smpd3fro/Smpd3fro Not Specified J:3906 View
osteogenesis imperfecta type 5 SucoGt(KST050)Byg/SucoGt(KST050)Byg involves: 129P2/OlaHsd * C57BL/6 * CD-1 J:159823 View
spondyloepimetaphyseal dysplasia Col2a1Rgsc413/Col2a1Rgsc413 involves: C57BL/6JJcl * DBA/2JJcl J:260538 View
spondyloepimetaphyseal dysplasia Col2a1Rgsc856/Col2a1Rgsc856 involves: C57BL/6JJcl * DBA/2JJcl J:171906 View
spondyloepiphyseal dysplasia congenita Hapln1tm1Nid/Hapln1tm1Nid involves: 129S1/Sv * 129X1/SvJ J:52575 View
thanatophoric dysplasia Hspg2tm1Nid/Hspg2tm1Nid involves: 129X1/SvJ * C57BL/6 J:67299 View
Weissenbacher-Zweymuller syndrome Acvr2atm1Zuk/Acvr2atm1Zuk either: 129 or (involves: 129S7/SvEvBrd * C57BL/6) J:23924 View
Weissenbacher-Zweymuller syndrome Mapk1tm1Gela/Mapk1tm1Gela
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * CBA/J J:239772 View
Weissenbacher-Zweymuller syndrome Sox11tm1.1Gan/Sox11tm1.1Gan
Tg(EIIa-cre)C5379Lmgd/0
involves: 129S6/SvEvTac * C57BL/6 * FVB/N J:232434 View
Weissenbacher-Zweymuller syndrome hpmd/hpmd Not Specified J:75360 View
Transgenes and
Other Mutations
     osteogenesis imperfecta type 5 Tg(Col1a1-Ifitm5*)1Brle/0 involves: FVB/N J:233366 View


       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      achondroplasia Fgfr3tm1Dor/Fgfr3tm1Dor involves: 129S6/SvEvTac * C57BL/6 J:32991 View
multiple epiphyseal dysplasia Comptm1Aol/Comptm1Aol involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:76781 View
osteogenesis imperfecta type 5 Ifitm5em1Pmof/Ifitm5+ involves: CD-1 J:255349 View
pseudoachondroplasia Comptm1Aol/Comptm1Aol involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:76781 View
thanatophoric dysplasia Fgfr3tm1Cxd/Fgfr3tm1Cxd involves: 129S6/SvEvTac * NIH Black Swiss J:52438 View