Analysis Tools
growth/size/body
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• small but significant decrease in male body weight at 6 weeks of age but not at 4 months of age or in females
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hematopoietic system
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• osteoclast surfaces are increased in the lumbar spine
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• osteoclast numbers are increased in the lumbar spine
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immune system
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• osteoclast surfaces are increased in the lumbar spine
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• osteoclast numbers are increased in the lumbar spine
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skeleton
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• osteoclast surfaces are increased in the lumbar spine
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• osteoclast numbers are increased in the lumbar spine
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• both the inner medullary radius and endosteal circumference are smaller in males at 4 months of age resulting in a decreased medullary area
• however, morphology of growth plate is normal and no atypical skeletal malformations are seen at 6 weeks or 4 months of life
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• mid-shaft femurs of males show an increase in cortical thickness at 4 months of age
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• 4-month-old males show an elevated yield load (yield force) in a femoral three-point bending structural mechanical test
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limbs/digits/tail
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• both the inner medullary radius and endosteal circumference are smaller in males at 4 months of age resulting in a decreased medullary area
• however, morphology of growth plate is normal and no atypical skeletal malformations are seen at 6 weeks or 4 months of life
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Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| Smith-McCort dysplasia 2 | DOID:0081271 |
OMIM:615222 |
J:338833 | |
