Phenotypes Associated with This Genotype

Genotype
MGI:7264676

• Allelic Composition: Cant1^tm1.1Aros/Cant1^tm1.1Aros
• Genetic Background: involves: 129 * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body size ( J:282272 )

• mice exhibit reduced size at P60

limbs/digits/tail

abnormal phalanx morphology ( J:282272 )

• medial deviation of the first digit in the extremities with the formation of an additional rudimentary phalanx called a delta phalanx

skeleton

abnormal phalanx morphology ( J:282272 )

• medial deviation of the first digit in the extremities with the formation of an additional rudimentary phalanx called a delta phalanx

kyphosis ( J:282272 )

• mice exhibit a moderate thoracic kyphosis at P60

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Desbuquois dysplasia		DOID:0060462	OMIM:251450 OMIM:615777	J:282272