Excel File Text File All mouse models of Parkinson's disease with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      Kufor-Rakeb syndrome Atp13a2tm1.2Wtd/Atp13a2tm1.2Wtd involves: 129 * C57BL/6 J:221680 View
Parkinson's disease 1 Sncatm1Rosl/Sncatm1Rosl
Tg(SNCA*A30P)192Rwm/0
B6.Cg-Sncatm1Rosl Tg(SNCA*A30P)#Rwm J:201961 View
Parkinson's disease 1 Sncatm1Rosl/Sncatm1Rosl
Tg(SNCA)OVX37Rwm/0
B6.Cg-Tg(SNCA)OVX37Rwm Sncatm1Rosl J:201991 View
Parkinson's disease 1 Tg(THY1-SNCA*A53T)M53Sud/0 B6.Cg-Tg(THY1-SNCA*A53T)M53Sud/J J:212732 View
Parkinson's disease 1 Tg(SNCA)ARyot/0 C57BL/6J-Tg(SNCA)ARyot J:185434 View
Parkinson's disease 1 Sncatm1.1Koks/Snca+ either: B6.129P2-Sncatm1.1Koks or (involves: 129P2/OlaHsd * C57BL/6) J:201391 View
Parkinson's disease 1 Gt(ROSA)26Sortm2(SNCA*119)Djmo/Gt(ROSA)26Sortm2(SNCA*119)Djmo
7630403G23RikTg(Th-cre)1Tmd/7630403G23Rik+
involves: 129 * C57BL/6 J:150777 View
Parkinson's disease 1 Gt(ROSA)26Sortm2(SNCA*119)Djmo/Gt(ROSA)26Sortm2(SNCA*119)Djmo
7630403G23RikTg(Th-cre)1Tmd/7630403G23Rik+
involves: 129 * C57BL/6 * SJL J:150777 View
Parkinson's disease 1 Sncatm1Nbm/Sncatm1Nbm
Tg(SNCA*A30P)1Nbm/Tg(SNCA*A30P)1Nbm
Tg(SNCA*A30P)2Nbm/Tg(SNCA*A30P)2Nbm
involves: 129S6/SvEvTac * FVB/N J:156741 View
Parkinson's disease 1 Sncatm1Nbm/Sncatm1Nbm
Tg(SNCA*A53T)1Nbm/Tg(SNCA*A53T)1Nbm
Tg(SNCA*A53T)2Nbm/Tg(SNCA*A53T)2Nbm
involves: 129S6/SvEvTac * FVB/N J:156741 View
Parkinson's disease 1 Sncatm1Rosl/Sncatm1Rosl involves: 129X1/SvJ * C57BL/6 J:60151 View
Parkinson's disease 1 Tg(Prnp-SNCA*A53T)83Vle/0 involves: C3H * C57BL/6 J:76657 View
Parkinson's disease 1 Tg(Prnp-SNCA*A53T)83Vle/Tg(Prnp-SNCA*A53T)83Vle involves: C3H * C57BL/6 J:76657 View
Parkinson's disease 1 Tg(Th-SNCA*)1702Yosh/0 involves: C3H * C57BL/6J J:125149 View
Parkinson's disease 1 2310039L15RikTg(Prnp-SNCA*A53T)23Mkle/0 involves: C3H/HeJ * C57BL/6J J:77344 View
Parkinson's disease 1 Tg(Prnp-SNCA*A53T)25Mkle/0 involves: C3H/HeJ * C57BL/6J J:77344 View
Parkinson's disease 1 Tg(Thy1-SNCA*A30P)18Pjk/Tg(Thy1-SNCA*A30P)18Pjk involves: C57BL/6 J:80181 View
Parkinson's disease 1 Tg(PDGFB-SNCA)4Ema/0 involves: C57BL/6 * DBA/2 J:60638, J:166985 View
Parkinson's disease 1 Tg(Thy1-SNCA)61Ema/0 involves: C57BL/6 * DBA/2 J:137490 View
Parkinson's disease 1 Tg(Snca-SNCA)#Galt/? involves: C57BL/6 * DBA/2 J:199939 View
Parkinson's disease 1 Tg(SNCA*E46K)3Elan/? involves: C57BL/6 * SJL J:200740 View
Parkinson's disease 1 Tg(Prnp-SNCA*A53T)AAub/? involves: FVB/N J:216589 View
Parkinson's disease 1 Tg(Prnp-SNCA*A53T)AAub/Tg(Prnp-SNCA*A53T)AAub involves: FVB/N J:181820, J:185489 View
Parkinson's disease 1 Tg(PDGFB-SNCA*A53T)8Ema/0 Not Specified J:226922 View
Parkinson's disease 2 Prkntm1Roo/Prkntm1Roo either: 129S2/SvPas or (involves: 129S2/SvPas * C57BL/6) J:85561 View
Parkinson's disease 2 Tg(Slc6a3-PARK2*Q311X)AXwy/0 FVB/NJ-Tg(Slc6a3-PARK2*Q311X)AXwy J:146833 View
Parkinson's disease 2 Prkntm1Ykt/Prkntm1Ykt
Tg(Prp-GPR37)1Ryot/0
involves: 129P2/OlaHsd * C3H * C57BL/6 J:140326 View
Parkinson's disease 2 Prkntm1Ykt/Prkntm1Ykt
Tg(Prp-GPR37)1Ryot/Tg(Prp-GPR37)1Ryot
involves: 129P2/OlaHsd * C3H * C57BL/6 J:140326 View
Parkinson's disease 2 Prkntm1Ykt/Prkntm1Ykt
Tg(PDGFB-GPR37)20Ryot/0
involves: 129P2/OlaHsd * C57BL/6 J:140326 View
Parkinson's disease 2 Prkntm1Ykt/Prkntm1Ykt
Tg(PDGFB-GPR37)20Ryot/Tg(PDGFB-GPR37)20Ryot
involves: 129P2/OlaHsd * C57BL/6 J:140326 View
Parkinson's disease 2 Prkntm1Ccs/Prkntm1Ccs involves: 129S1/Sv * 129X1/SvJ * C57BL/6J J:168847 View
Parkinson's disease 2 Prkntm1Roo/Prkntm1Roo involves: 129S2/SvPas J:125148 View
Parkinson's disease 2 Prkntm1Shn/Prkntm1Shn involves: 129S4/SvJae J:86377 View
Parkinson's disease 2 Prkntm1Tmd/Prkntm1Tmd involves: C57BL/6 J:91487 View
Parkinson's disease 4 Tg(Thy1-Snca)1S13Putt/? involves: C57BL/6 J:177661 View
Parkinson's disease 6 Pink1tm1.1Wrst/Pink1tm1.1Wrst involves: 129S2/SvPas * BALB/cJ * C57BL/6J J:183290 View
Parkinson's disease 6 Pink1tm1Shn/Pink1tm1Shn involves: 129S4/SvJae * C57BL/6 J:122728 View
Parkinson's disease 6 Pink1tm1Hbu/Pink1tm1Hbu involves: 129S7/SvEvBrd * C57BL/6 J:169471 View
Parkinson's disease 6 Pink1tm1Aub/Pink1tm1Aub involves: 129S/SvEv J:150206 View
Parkinson's disease 7 Park7tm1Dsp/Park7tm1Dsp B6.129P2-Park7tm1Dsp J:190315 View
Parkinson's disease 7 Park7tm1Shn/Park7tm1Shn involves: 129 * C57BL/6 J:98436 View
Parkinson's disease 7 Park7tm1Xz/Park7tm1Xz involves: 129P2/OlaHsd * C57BL/6J J:99905 View
Parkinson's disease 7 Park7tm1Cai/Park7tm1Cai involves: 129X1/SvJ * C57BL/6 J:141628 View
Parkinson's disease 8 Khdrbs2Tg(LRRK2*R1441G)135Cjli/Khdrbs2+ FVB-Khdrbs2Tg(LRRK2*R1441G)135Cjli J:149135 View
Parkinson's disease 8 Khdrbs2Tg(LRRK2*R1441G)135Cjli/Khdrbs2+ FVB/N-Khdrbs2Tg(LRRK2*R1441G)135Cjli/J J:204940 View
Parkinson's disease 8 Tg(PDGFB-LRRK2*G2019S)32Hlw/? FVB/N-Tg(PDGFB-LRRK2*G2019S)32Hlw J:204793 View
Parkinson's disease 8 Tg(PDGFB-LRRK2*R1441C)31Hlw/0 FVB/N-Tg(PDGFB-LRRK2*R1441C)31Hlw J:229559 View
Parkinson's disease 8 Tg(Lrrk2*G2019S)2Yue/0 involves: C3H * C57BL/6 * C57BL/6J J:157931 View
Parkinson's disease 17 Vps35Gt(RRK261)Byg/Vps35+ B6.129P2-Vps35Gt(RRK261)Byg J:225806 View
      Parkinson's disease Adh7tm1Gdu/Adh7tm1Gdu B6.129(Cg)-Adh7tm1Gdu J:167234 View
Parkinson's disease Cox10tm1Ctm/Cox10tm1Ctm
Slc6a3tm1.1(cre)Bkmn/?
B6.Cg-Cox10tm1Ctm Slc6a3tm1.1(cre)Bkmn J:231810 View
Parkinson's disease Pitx3tm1.1Cai/Pitx3+
Tg(tetO-SNCA*A53T)E2Cai/0
involves: 129 * C57BL/6J * FVB/N J:185958 View
Parkinson's disease Rrn3tm1.1Igt/Rrn3tm1.1Igt
Tg(Slc6a3-cre/ERT2)1Span/0
involves: 129/Sv * C57BL/6 J:168232, J:242309 View
Parkinson's disease Rrn3tm1.1Igt/Rrn3tm1.1Igt
Tg(Slc6a3-icre)9190Gsc/0
involves: 129/Sv * C57BL/6 * FVB/N J:168232 View
Parkinson's disease Slc6a3tm1(cre)Lrsn/Slc6a3+
Tfamtm1Lrsn/Tfamtm1Lrsn
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL J:119515 View
Parkinson's disease Atg7tm1Tchi/Atg7tm1Tchi
En1tm2(cre)Wrst/En1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj J:192452 View
Parkinson's disease Pitx3ak/Pitx3ak involves: 129S1/Sv * C57BL/6 * C57BLKS/J J:98209 View
Parkinson's disease Atg7tm1Tchi/Atg7tm1Tchi
Slc6a3tm1(cre)Xz/Slc6a3+
involves: 129S1/Sv * C57BL/6NCrlj * CBA/JNCrlj J:192452 View
Parkinson's disease Drd2tm1Ebo/Drd2tm1Ebo involves: 129S2/SvPas * C57BL/6 J:29045 View
Parkinson's disease Nr4a2tm1Omc/Nr4a2+ involves: 129S7/SvEvBrd * C57BL/6 J:104902 View
Parkinson's disease Sprtm1Lex/Sprtm1Lex involves: 129S/SvEvBrd * C57BL/6J J:131376 View
Parkinson's disease Adcy5tm1Yish/Adcy5tm1Yish involves: 129X1/SvJ * C57BL/6 J:83301 View
Parkinson's disease Kcnn2fri/Kcnn2fri involves: C3H J:70213 View
Parkinson's disease Pitx3eyl/Pitx3eyl involves: C3H/He * C57BL/6 J:156878 View
Parkinson's disease Tg(Th-Twnk*,-EGFP)2Gcor/0 involves: C57BL/6J J:188914 View
Parkinson's disease nm3/nm3 involves: RIIIS/J J:88298 View
Transgenes and
Other Mutations
     Parkinson's disease Tg(PDGF-S100B)36Cqin/0 C57BL/6-Tg(PDGF-S100B)36Cqin J:173682 View
Parkinson's disease Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-SNCA)0Olri/0
involves: C57BL/6 J:132774 View
Parkinson's disease Tg(Th-SNCA)5Eric/Tg(Th-SNCA)5Eric involves: C57BL/6 J:140907 View
Parkinson's disease Tg(CAG-SNCA*)1.1Ccs/? involves: C57BL/6 J:168847 View
Parkinson's disease Tg(Th-SNCA*)1.2Ccs/? involves: C57BL/6 J:168847 View
Parkinson's disease Tg(Gfap-rtTA,tetO-MAOB,-lacZ)1Jkan/0 involves: C57BL/6 J:132679 View
Parkinson's disease Tg(Snca-SNCA/GFP)#Jyl/Tg(Snca-SNCA/GFP)#Jyl involves: C57BL/6 J:197984 View
Parkinson's disease Tg(Th-SNCA)5Eric/0 involves: C57BL/6 * C57BL/6J J:96494 View
Parkinson's disease Tg(Th-SNCA*A30P*A53T)39Eric/0 involves: C57BL/6 * C57BL/6J J:96494 View
Parkinson's disease Tg(GFAP-tTA)6Hyms/0
Tg(tetO-HMOX1)6Hyms/0
involves: FVB/N J:190573 View
Parkinson's disease 1 Tg(Thy1-SNCA*E57K)16Ema/0 involves: C57BL/6 * DBA/2 J:236596 View
Parkinson's disease 1 Tg(PDGFB-SNCA/EGFP)78Ema/0 involves: C57BL/6 * DBA/2 J:238692 View
Additional
Complex
Models
     Parkinson's disease Gt(ROSA)26Sortm1.1(CAG-COX8A/Dendra2)Dcc/Gt(ROSA)26Sor+
Mfn2tm3Dcc/Mfn2tm3Dcc
Slc6a3tm1.1(cre)Bkmn/Slc6a3+
involves: 129 * 129S6/SvEvTac * C57BL/6J * SJL/J J:188347 View
Parkinson's disease Tg(Thy1-Snca)1S13Putt/0
Uchl1tm1Dgen/Uchl1tm1Dgen
involves: 129P2/OlaHsd * C57BL/6 J:207278 View
Parkinson's disease Lmx1atm1Tpe/Lmx1atm1Tpe
Lmx1btm1Zfc/Lmx1btm1Zfc
Slc6a3tm1(cre)Lrsn/Slc6a3+
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 J:222854 View
Parkinson's disease En1tm2Alj/En1+
Tg(Th-EGFP)6-7Okn/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2J * OF1 J:214073 View
Parkinson's disease Pink1tm1.1Wrst/Pink1tm1.1Wrst
Tg(Prnp-SNCA*A53T)AAub/?
involves: 129S2/SvPas * C57BL/6J * FVB/N J:242309 View
Parkinson's disease En1tm1Gld/En1+
En2tm1Alj/En2tm1Alj
involves: 129S/SvEv * 129S2/SvPas * C57BL/6 * Swiss Webster J:115270 View
Parkinson's disease Pink1tm1Aub/Pink1tm1Aub
Tg(Prnp-SNCA*A53T)AAub/Tg(Prnp-SNCA*A53T)AAub
involves: 129S/SvEv * FVB/N J:214065 View
Parkinson's disease Slc6a3tm2(tTA)Xz/Slc6a3+
Tg(tetO-COX8A/PstI*)1Ctm/0
involves: 129X1/SvJ * C57BL/6 * C57BL/6J * SJL J:178139 View


       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      Parkinson's disease Drd2tm1Low/Drd2tm1Low B6.129S2-Drd2tm1Low J:47001 View