LmnaDhe/Lmna+
B6(D2)-LmnaDhe/TyGrsrJ
|
abnormal auditory bulla morphology |
J:188496
|
|
abnormal auditory tube morphology |
J:188496
|
|
abnormal bone mineralization |
J:160175
|
|
abnormal cell cycle |
J:171665
|
|
abnormal cell nucleus morphology |
J:171665
|
|
abnormal coat/hair pigmentation |
J:160175
|
|
abnormal coronal suture morphology |
J:160175
|
|
abnormal cranial suture morphology |
J:160175
|
|
abnormal cranium size |
J:160175
|
|
abnormal distortion product otoacoustic emission |
J:188496
|
|
abnormal DNA replication |
J:171665
|
|
abnormal ear development |
J:188496
|
|
abnormal ear morphology |
J:188496
|
|
abnormal ear physiology |
J:188496
|
|
abnormal frontonasal suture morphology |
J:160175
|
|
abnormal lambdoid suture morphology |
J:160175
|
|
abnormal middle ear epithelium morphology |
J:188496
|
|
abnormal middle ear morphology |
J:188496
|
|
abnormal mitosis |
J:171665
|
|
abnormal mitotic spindle assembly checkpoint |
J:171665
|
|
abnormal nasopharynx morphology |
J:188496
|
|
abnormal neurocranium morphology |
J:160175
|
|
abnormal nuclear lamina morphology |
J:160175,
J:171665,
J:188496
|
|
abnormal peritoneal macrophage morphology |
J:188496
|
|
abnormal sagittal suture morphology |
J:160175
|
|
abnormal tympanic membrane morphology |
J:188496
|
|
aneuploidy |
J:171665
|
|
decreased body size |
J:160175
|
|
decreased body weight |
J:160175
|
|
decreased bone mineral content |
J:160175
|
|
decreased bone mineral density |
J:160175
|
|
decreased cranium height |
J:160175
|
|
decreased cranium width |
J:160175
|
|
decreased fibroblast proliferation |
J:171665
|
|
decreased total body fat amount |
J:160175
|
|
exophthalmos |
J:160175
|
|
flaky skin |
J:160175
|
|
impaired hearing |
J:188496
|
|
increased circulating phosphate level |
J:188496
|
|
increased middle ear goblet cell number |
J:188496
|
|
increased or absent threshold for auditory brainstem response |
J:188496
|
|
increased susceptibility to otitis media |
J:188496
|
|
malocclusion |
J:160175
|
|
mandible hypoplasia |
J:160175
|
|
ocular hypotelorism |
J:160175
|
|
premature aging |
J:160175
|
|
reduced female fertility |
J:160175
|
|
rough coat |
J:160175
|
|
shallow orbits |
J:160175
|
|
short ears |
J:160175
|
|
short maxilla |
J:160175
|
|
short snout |
J:160175
|
|
short upper incisors |
J:160175
|
|
small cranium |
J:160175
|
|
sparse hair |
J:160175
|
|
tympanic membrane retraction |
J:188496
|
LmnaDhe/LmnaDhe
B6(D2)-LmnaDhe/TyGrsrJ
|
abnormal cranium morphology |
J:160175
|
|
abnormal epidermal layer morphology |
J:160175
|
|
abnormal epidermal melanocyte morphology |
J:160175
|
|
abnormal epidermis stratum basale morphology |
J:160175
|
|
abnormal epidermis stratum granulosum morphology |
J:160175
|
|
abnormal hair cycle anagen phase |
J:160175
|
|
abnormal hard palate morphology |
J:160175
|
|
abnormal keratinocyte morphology |
J:160175
|
|
abnormal neurocranium morphology |
J:160175
|
|
abnormal nuclear lamina morphology |
J:160175
|
|
abnormal sagittal suture morphology |
J:160175
|
|
abnormal tail morphology |
J:160175
|
|
abnormal tongue morphology |
J:160175
|
|
alopecia |
J:160175
|
|
decreased bone mineralization |
J:160175
|
|
decreased subcutaneous adipose tissue amount |
J:160175
|
|
epidermal hyperplasia |
J:160175
|
|
orthokeratosis |
J:160175
|
|
premature death |
J:160175
|
|
sebaceous gland hypoplasia |
J:160175
|
|
thick epidermis |
J:160175
|
Lmnaem1Fenz/Lmna+
C57BL/6-Lmnaem1Fenz
|
abnormal inguinal fat pad morphology |
J:338760
|
|
abnormal respiratory electron transport chain |
J:338760
|
|
normal
adipose tissue phenotype |
J:338760
|
|
decreased white adipose tissue mass |
J:338760
|
|
hepatic steatosis |
J:338760
|
|
impaired glucose tolerance |
J:338760
|
|
increased abdominal fat pad weight |
J:338760
|
|
increased body weight |
J:338760
|
|
increased brown adipose tissue mass |
J:338760
|
|
increased circulating alanine transaminase level |
J:338760
|
|
increased circulating alkaline phosphatase level |
J:338760
|
|
increased circulating aspartate transaminase level |
J:338760
|
|
increased circulating cholesterol level |
J:338760
|
|
increased circulating LDL cholesterol level |
J:338760
|
|
increased liver triglyceride level |
J:338760
|
|
increased renal fat pad weight |
J:338760
|
|
insulin resistance |
J:338760
|
LmnaGt(S7-1F1)Sor/Lmna+
involves: 129S4/SvJaeSor * C57BL/6
|
no abnormal phenotype detected |
J:221850
|
LmnaGt(S7-1F1)Sor/LmnaGt(S7-1F1)Sor
involves: 129S4/SvJaeSor * C57BL/6
|
abnormal fat cell differentiation |
J:221850
|
|
abnormal gait |
J:221850
|
|
abnormal heart development |
J:221850
|
|
abnormal mitochondrial ATP synthesis coupled electron transport |
J:221850
|
|
abnormal suckling behavior |
J:221850
|
|
normal
craniofacial phenotype |
J:221850
|
|
decreased body weight |
J:221850
|
|
decreased circulating carnitine level |
J:221850
|
|
decreased circulating lactate level |
J:221850
|
|
decreased core body temperature |
J:221850
|
|
decreased grip strength |
J:221850
|
|
decreased heart left ventricle weight |
J:221850
|
|
decreased heart rate |
J:221850
|
|
decreased liver glycogen level |
J:221850
|
|
decreased myocardial fiber size |
J:221850
|
|
decreased quadriceps weight |
J:221850
|
|
decreased skeletal muscle fiber diameter |
J:221850
|
|
decreased skeletal muscle fiber size |
J:221850
|
|
decreased subcutaneous adipose tissue amount |
J:221850
|
|
hunched posture |
J:221850
|
|
hypoglycemia |
J:221850
|
|
increased circulating creatine kinase level |
J:221850
|
|
increased circulating ketone body level |
J:221850
|
|
meteorism |
J:221850
|
|
normal
mortality/aging |
J:221850
|
|
muscle weakness |
J:221850
|
|
poor grooming |
J:221850
|
|
postnatal growth retardation |
J:221850
|
|
postnatal lethality, complete penetrance |
J:221850
|
|
prolonged P wave |
J:221850
|
|
prolonged RR interval |
J:221850
|
|
normal
skeleton phenotype |
J:221850
|
Lmnatm1.1Bliu/Lmna+
involves: C57BL/6 * FVB/N
|
abnormal vasodilation |
J:287256
|
|
postnatal growth retardation |
J:287256
|
|
premature death |
J:287256
|
Lmnatm1.1Bliu/Lmnatm1.1Bliu
involves: C57BL/6 * FVB/N
|
abnormal vasodilation |
J:287256
|
|
increased aorta wall thickness |
J:287256
|
|
postnatal growth retardation |
J:287256
|
|
premature death |
J:287256
|
|
weight loss |
J:287256
|
Lmnatm1.1Otin/Lmna+
involves: 129P2/OlaHsd * C57BL/6
|
abnormal blood homeostasis |
J:211388
|
|
abnormal cell nucleus morphology |
J:177575,
J:177632
|
|
abnormal vascular smooth muscle physiology |
J:211388
|
|
calcified aorta |
J:211388
|
|
calcified aortic arch |
J:211388
|
|
calcified thoracic aorta |
J:211388
|
|
decreased circulating glucose level |
J:177632
|
|
increased circulating alkaline phosphatase level |
J:211388
|
|
premature death |
J:177575,
J:177632
|
|
weight loss |
J:177632
|
Lmnatm1.1Otin/Lmna+
involves: 129P2/OlaHsd * C57BL/6NTac
|
premature aging |
J:261974
|
Lmnatm1.1Otin/Lmnatm1.1Otin
involves: 129P2/OlaHsd * C57BL/6
|
abnormal blood homeostasis |
J:177632
|
|
abnormal bone structure |
J:177632
|
|
abnormal cell nucleus morphology |
J:177575,
J:177632
|
|
abnormal cell physiology |
J:177632
|
|
abnormal hair follicle morphology |
J:177632
|
|
calcified aorta |
J:211388
|
|
decreased bone mineral density |
J:177632
|
|
decreased bone trabecula number |
J:177632
|
|
decreased bone volume |
J:177632
|
|
decreased circulating insulin level |
J:177632
|
|
decreased circulating leptin level |
J:177632
|
|
decreased compact bone thickness |
J:177632
|
|
decreased grip strength |
J:177632
|
|
decreased heart rate |
J:177632
|
|
decreased subcutaneous adipose tissue amount |
J:177632
|
|
hypoglycemia |
J:177632
|
|
increased circulating adiponectin level |
J:177632
|
|
increased circulating growth hormone level |
J:177632
|
|
infertility |
J:177632
|
|
lordokyphosis |
J:177632
|
|
postnatal growth retardation |
J:177632
|
|
premature aging |
J:177632
|
|
premature death |
J:177575,
J:177632
|
|
prolonged QRS complex duration |
J:177632
|
|
small cranium |
J:177632
|
|
small lower incisors |
J:177632
|
|
small spleen |
J:177632
|
|
small thymus |
J:177632
|
|
vascular smooth muscle hypoplasia |
J:177632
|
|
weight loss |
J:177632
|
Lmnatm1.1Otin/Lmnatm1.1Otin
involves: 129P2/OlaHsd * C57BL/6NTac
|
abnormal aorta tunica adventitia morphology |
J:261974
|
|
decreased body weight |
J:261974
|
|
decreased heart rate |
J:261974
|
|
decreased subcutaneous adipose tissue amount |
J:261974
|
|
female infertility |
J:261974
|
|
keratoconjunctivitis sicca |
J:261974
|
|
kyphosis |
J:261974
|
|
oligozoospermia |
J:261974
|
|
penis prolapse |
J:261974
|
|
premature death |
J:261974
|
|
reduced male fertility |
J:261974
|
Lmnatm1.1Vde/Lmnatm1.1Vde
B6.129(Cg)-Lmnatm1.1Vde
|
abnormal muscle tone |
J:322912
|
|
normal
behavior/neurological phenotype |
J:322912
|
|
enhanced exercise endurance |
J:322912
|
|
normal
nervous system phenotype |
J:322912
|
Lmnatm1.1Yxz/Lmnatm1.1Yxz
involves: 129S4/SvJae * C57BL/6 * CD-1 * SJL
|
no abnormal phenotype detected |
J:211369
|
Lmnatm1.2Yxz/Lmnatm1.2Yxz
involves: 129S * BALB/cJ * C57BL/6 * CD-1 * SJL
|
decreased body weight |
J:211369
|
|
decreased skeletal muscle fiber size |
J:211369
|
|
postnatal growth retardation |
J:211369
|
|
postnatal lethality, complete penetrance |
J:211369
|
Lmnatm1b(EUCOMM)Wtsi/Lmna+
C57BL/6N-Lmnatm1b(EUCOMM)Wtsi/Ics
|
cornea ulcer |
J:211773
|
|
improved glucose tolerance |
J:211773
|
|
short tibia |
J:211773
|
Lmnatm1b(EUCOMM)Wtsi/Lmnatm1b(EUCOMM)Wtsi
C57BL/6N-Lmnatm1b(EUCOMM)Wtsi/Ics
|
preweaning lethality, complete penetrance |
J:211773
|
Lmnatm1Bliu/Lmna+
Tg(Tek-cre)1Ywa/0
involves: C57BL/6 * SJL
|
abnormal artery morphology |
J:287256
|
|
abnormal physiological neovascularization |
J:287256
|
|
abnormal vasodilation |
J:287256
|
|
atherosclerotic lesions |
J:287256
|
|
cardiac fibrosis |
J:287256
|
|
decreased bone trabecula number |
J:287256
|
|
decreased capillary density |
J:287256
|
|
decreased cardiac output |
J:287256
|
|
decreased heart rate |
J:287256
|
|
decreased trabecular bone thickness |
J:287256
|
|
decreased trabecular bone volume |
J:287256
|
|
decreased vascular endothelial cell number |
J:287256
|
|
decreased ventricle muscle contractility |
J:287256
|
|
dilated cardiomyopathy |
J:287256
|
|
impaired exercise endurance |
J:287256
|
|
increased aorta wall thickness |
J:287256
|
|
increased bone trabecular spacing |
J:287256
|
|
osteoporosis |
J:287256
|
|
premature aging |
J:287256
|
|
premature death |
J:287256
|
|
weight loss |
J:287256
|
Lmnatm1Gbon/Lmna+
involves: 129S2/SvPas * C57BL/6
|
no abnormal phenotype detected |
J:95528
|
Lmnatm1Gbon/Lmnatm1Gbon
involves: 129S2/SvPas * C57BL/6
|
abnormal diaphragm morphology |
J:95528
|
|
abnormal gait |
J:95528
|
|
abnormal gastrocnemius morphology |
J:95528
|
|
abnormal hypaxial muscle morphology |
J:95528
|
|
abnormal impulse conducting system conduction |
J:95528
|
|
abnormal myocardial fiber morphology |
J:95528
|
|
abnormal soleus morphology |
J:95528
|
|
abnormal tibialis anterior morphology |
J:95528
|
|
bradykinesia |
J:95528
|
|
cardiac fibrosis |
J:95528
|
|
decreased body weight |
J:95528
|
|
decreased cardiac muscle contractility |
J:95528,
J:187399
|
|
decreased circulating glucose level |
J:95528
|
|
dilated cardiomyopathy |
J:187399
|
|
dilated heart atrium |
J:95528
|
|
dilated heart left ventricle |
J:95528,
J:187399
|
|
dilated heart right ventricle |
J:95528
|
|
dystrophic muscle |
J:95528
|
|
enlarged heart |
J:95528
|
|
hunched posture |
J:95528
|
|
impaired coordination |
J:95528
|
|
increased triglyceride level |
J:95528
|
|
myocardium necrosis |
J:95528
|
|
postnatal growth retardation |
J:95528
|
|
premature death |
J:95528
|
|
progressive muscle weakness |
J:95528
|
|
prolonged PR interval |
J:95528
|
|
prolonged QRS complex duration |
J:95528
|
|
sinoatrial block |
J:95528
|
|
skeletal muscle fibrosis |
J:95528
|
|
tachypnea |
J:95528
|
Lmnatm1Lgf/Lmna+
involves: 129P2/OlaHsd * C57BL/6
|
abnormal bone mineralization |
J:113119
|
|
abnormal bone structure |
J:113119
|
|
abnormal cell nucleus morphology |
J:100220,
J:141165,
J:146099
|
|
abnormal cranial suture morphology |
J:113119
|
|
abnormal rib morphology |
J:113119,
J:141165
|
|
abnormal zygomatic arch morphology |
J:113119
|
|
normal
behavior/neurological phenotype |
J:113119
|
|
decreased abdominal adipose tissue amount |
J:113119
|
|
decreased body weight |
J:141165,
J:146099
|
|
decreased bone mineral density |
J:141165
|
|
decreased percent body fat/body weight |
J:141165
|
|
decreased subcutaneous adipose tissue amount |
J:113119
|
|
kyphosis |
J:113119,
J:141165
|
|
micrognathia |
J:113119
|
|
premature death |
J:113119,
J:141165,
J:146099
|
|
rib fractures |
J:113119,
J:141165
|
|
weight loss |
J:113119
|
Lmnatm1Lgf/Lmnatm1Lgf
involves: 129P2/OlaHsd * C57BL/6
|
abnormal cell nucleus morphology |
J:113119,
J:141165
|
|
abnormal cranium morphology |
J:113119
|
|
abnormal skeleton morphology |
J:113119
|
|
decreased body size |
J:113119
|
|
decreased bone mineralization |
J:113119
|
|
decreased total body fat amount |
J:113119
|
|
micrognathia |
J:113119
|
|
premature death |
J:113119
|
|
wide cranial sutures |
J:113119
|
Lmnatm1Lgf/Lmnatm1Stw
involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6
|
abnormal skeleton morphology |
J:113119
|
|
premature death |
J:113119
|
Lmnatm1Otin/Lmnatm1Otin
involves: 129P2/OlaHsd * C57BL/6
|
no abnormal phenotype detected |
J:177632
|
Lmnatm1Rben/Lmnatm1Rben
involves: 129S1/Sv * 129X1/SvJ
|
abnormal chromosomal synapsis |
J:223056
|
|
abnormal double-strand DNA break repair |
J:223056
|
|
abnormal female meiosis |
J:223056
|
|
abnormal meiosis |
J:223056
|
|
abnormal reproductive system morphology |
J:223056
|
|
arrest of male meiosis |
J:223056
|
|
azoospermia |
J:223056
|
|
male infertility |
J:223056
|
|
normal
reproductive system phenotype |
J:223056
|
|
small testis |
J:223056
|
Lmnatm1Stw/Lmna+
involves: 129S1/Sv
|
abnormal cell nucleus morphology |
J:58702
|
Lmnatm1Stw/Lmna+
involves: 129S1/Sv * C57BL/6J
|
normal
adipose tissue phenotype |
J:75101
|
|
increased circulating insulin level |
J:75101
|
|
insulin resistance |
J:75101
|
|
normal
liver/biliary system phenotype |
J:75101
|
Lmnatm1Stw/Lmnatm1Stw
involves: 129S1/Sv
|
abnormal axon morphology |
J:75378
|
|
abnormal cell nucleus morphology |
J:58702
|
|
abnormal gait |
J:58702
|
|
abnormal myelination |
J:75378
|
|
abnormal sciatic nerve morphology |
J:75378
|
|
decreased body weight |
J:58702
|
|
decreased grip strength |
J:58702
|
|
decreased white adipose tissue amount |
J:58702
|
|
dystrophic muscle |
J:58702
|
|
kyphoscoliosis |
J:58702
|
|
muscle degeneration |
J:58702
|
|
postnatal growth retardation |
J:58702
|
|
premature death |
J:58702
|
|
small spleen |
J:58702
|
|
thymus atrophy |
J:58702
|
Lmnatm1Stw/Lmnatm1Stw
involves: 129S1/Sv * C57BL/6
|
arrest of male meiosis |
J:88595
|
|
azoospermia |
J:88595
|
|
muscle weakness |
J:95274
|
|
postnatal growth retardation |
J:95274
|
|
premature death |
J:95274
|
|
small seminiferous tubules |
J:88595
|
|
small testis |
J:88595
|
Lmnatm1Stw/Lmnatm1Stw
involves: 129S1/Sv * C57BL/6J
|
decreased circulating glucose level |
J:75101
|
|
decreased circulating triglyceride level |
J:75101
|
Lmnatm1Stw/Lmnatm2Lgf
involves: 129S1/Sv * 129S4/SvJae * C57BL/6
|
no abnormal phenotype detected |
J:106473
|
Lmnatm1Stw/Lmnatm7Lgf
involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6
|
abnormal cell nucleus morphology |
J:165928
|
Lmnatm2.1Gbon/Lmna+
involves: 129 * C57BL/6
|
abnormal heart echocardiography feature |
J:198526
|
|
abnormal heart morphology |
J:198526
|
|
abnormal sarcomere morphology |
J:198526
|
|
cardiac fibrosis |
J:198526
|
|
cardiac hypertrophy |
J:198526
|
|
cardiac muscle degeneration |
J:198526
|
|
congestive heart failure |
J:198526
|
|
decreased cardiac muscle contractility |
J:198526
|
|
decreased heart rate |
J:198526
|
|
dilated cardiomyopathy |
J:198526
|
|
dilated heart left ventricle |
J:198526
|
|
normal
homeostasis/metabolism phenotype |
J:198526
|
|
increased heart atrium size |
J:198526
|
|
normal
muscle phenotype |
J:198526
|
|
premature death |
J:198526
|
|
prolonged PR interval |
J:198526
|
|
prolonged QRS complex duration |
J:198526
|
|
pulmonary edema |
J:198526
|
Lmnatm2.1Gbon/Lmnatm2.1Gbon
involves: 129 * C57BL/6
|
abnormal behavior |
J:180603
|
|
abnormal cell differentiation |
J:180603
|
|
abnormal gait |
J:180603
|
|
abnormal heart development |
J:180603
|
|
abnormal muscle development |
J:180603
|
|
abnormal myocardial fiber morphology |
J:180603
|
|
abnormal urine homeostasis |
J:180603
|
|
centrally nucleated skeletal muscle fibers |
J:180603
|
|
decreased circulating insulin level |
J:180603
|
|
decreased heart weight |
J:180603
|
|
decreased skeletal muscle fiber size |
J:180603
|
|
decreased white adipose tissue amount |
J:180603
|
|
hypoglycemia |
J:180603
|
|
postnatal growth retardation |
J:180603
|
|
postnatal lethality, complete penetrance |
J:180603
|
|
slow postnatal weight gain |
J:180603
|
|
weight loss |
J:180603
|
Lmnatm2Lgf/Lmnatm2Lgf
involves: 129S4/SvJae * C57BL/6
|
no abnormal phenotype detected |
J:106473
|
Lmnatm2Lgf/Lmnatm7Lgf
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
|
abnormal cell nucleus morphology |
J:165928
|
Lmnatm2Stw/Lmnatm2Stw
involves: 129S1/Sv
|
abnormal cell nucleus morphology |
J:83382
|
|
abnormal esophageal smooth muscle morphology |
J:83382
|
|
abnormal gait |
J:83382
|
|
abnormal heart morphology |
J:83382
|
|
abnormal incisor morphology |
J:83382
|
|
abnormal scapula morphology |
J:83382
|
|
abnormal skin morphology |
J:83382
|
|
abnormal trabecular bone morphology |
J:83382
|
|
absent subcutaneous adipose tissue |
J:83382
|
|
cardiac muscle degeneration |
J:83382
|
|
decreased body height |
J:83382
|
|
decreased bone mineral density |
J:83382
|
|
decreased eccrine gland number |
J:83382
|
|
decreased hair follicle number |
J:83382
|
|
decreased myocardial fiber number |
J:83382
|
|
decreased myocardial fiber size |
J:83382
|
|
decreased sebaceous gland number |
J:83382
|
|
hyperkeratosis |
J:83382
|
|
normal
limbs/digits/tail phenotype |
J:83382
|
|
micrognathia |
J:83382
|
|
muscular atrophy |
J:83382
|
|
osteoporosis |
J:83382
|
|
postnatal growth retardation |
J:83382
|
|
premature aging |
J:83382
|
|
premature death |
J:83382
|
|
prominent ears |
J:83382
|
|
pulmonary hypertension |
J:83382
|
|
skeletal muscle degeneration |
J:83382
|
|
small gonad |
J:83382
|
|
small heart |
J:83382
|
|
small xiphoid process |
J:83382
|
|
thin dermal layer |
J:83382
|
Lmnatm3Lgf/Lmna+
involves: 129P2/OlaHsd * C57BL/6
|
decreased body weight |
J:141165
|
|
decreased percent body fat/body weight |
J:141165
|
|
kyphosis |
J:141165
|
|
premature death |
J:141165
|
|
rib fractures |
J:141165
|
|
normal
skeleton phenotype |
J:141165
|
Lmnatm3Lgf/Lmnatm3Lgf
involves: 129P2/OlaHsd
|
abnormal axial skeleton morphology |
J:167229
|
|
abnormal cell nucleus morphology |
J:167229
|
|
decreased body weight |
J:167229
|
|
decreased bone mineral density |
J:167229
|
|
decreased total body fat amount |
J:167229
|
|
premature death |
J:167229
|
|
rib fractures |
J:167229
|
Lmnatm3Lgf/Lmnatm3Lgf
involves: 129P2/OlaHsd * C57BL/6
|
abnormal cell nucleus morphology |
J:141165
|
|
decreased abdominal adipose tissue amount |
J:141165
|
|
decreased subcutaneous adipose tissue amount |
J:141165
|
|
premature death |
J:141165
|
|
rib fractures |
J:141165
|
|
weight loss |
J:141165
|
Lmnatm3Stw/Lmnatm3Stw
involves: 129S1/Sv * 129S4/SvJaeSor * C57BL
|
abnormal myocardial fiber morphology |
J:100393
|
|
cardiac interstitial fibrosis |
J:100393
|
|
cardiac muscle degeneration |
J:100393
|
|
decreased heart rate |
J:100393
|
|
decreased locomotor activity |
J:100393
|
|
decreased ventricle muscle contractility |
J:100393
|
|
dilated cardiomyopathy |
J:100393
|
|
disheveled coat |
J:100393
|
|
myocardial fiber degeneration |
J:100393
|
|
postnatal growth retardation |
J:100393
|
|
premature death |
J:100393
|
|
prolonged PR interval |
J:100393
|
|
thin myocardium |
J:100393
|
Lmnatm4Lgf/Lmna+
involves: 129P2/OlaHsd * C57BL/6
|
abnormal cell nucleus morphology |
J:146099
|
|
decreased body weight |
J:146099
|
|
premature death |
J:146099
|
|
rib fractures |
J:146099
|
Lmnatm4Stw/Lmnatm4Stw
Tg(Vil1-cre)997Gum/0
involves: C57BL/6 * C57BL/6J
|
no abnormal phenotype detected |
J:220874
|
Lmnatm4Stw/Lmnatm4Stw
Tg(Zp3-cre)93Knw/0
involves: C57BL/6J
|
abnormal gait |
J:220874
|
|
centrally nucleated skeletal muscle fibers |
J:220874
|
|
decreased body size |
J:220874
|
|
decreased body weight |
J:220874
|
|
decreased skeletal muscle fiber diameter |
J:220874
|
|
dystrophic muscle |
J:220874
|
|
kinked tail |
J:220874
|
|
postnatal growth retardation |
J:220874
|
|
postnatal lethality, complete penetrance |
J:220874
|
Lmnatm5Lgf/Lmnatm5Lgf
involves: 129P2/OlaHsd * C57BL/6
|
abnormal cell nucleus morphology |
J:160705
|
|
cardiac fibrosis |
J:160705
|
|
decreased body weight |
J:160705
|
|
decreased survivor rate |
J:160705
|
|
decreased ventricle muscle contractility |
J:160705
|
|
dilated cardiomyopathy |
J:160705
|
|
dilated heart left ventricle |
J:160705
|
|
premature death |
J:160705
|
|
normal
skeleton phenotype |
J:160705
|
Lmnatm6Lgf/Lmnatm6Lgf
involves: 129P2/OlaHsd
|
abnormal cell nucleus morphology |
J:165928
|
Lmnatm6Lgf/Lmnatm6Lgf
involves: 129P2/OlaHsd * C57BL/6
|
decreased body weight |
J:160705
|
Lmnatm7Lgf/Lmna+
involves: 129P2/OlaHsd * C57BL/6
|
abnormal cell nucleus morphology |
J:165928
|
Lmnatm7Lgf/Lmnatm7Lgf
involves: 129P2/OlaHsd * C57BL/6
|
abnormal cell nucleus morphology |
J:165928
|
|
normal
mortality/aging |
J:165928
|
|
normal
reproductive system phenotype |
J:165928
|
Lmnatm8Lgf/Lmnatm8Lgf
involves: 129P2/OlaHsd
|
abnormal cell nucleus morphology |
J:167229
|
|
abnormal heart left ventricle morphology |
J:167229
|
|
normal
adipose tissue phenotype |
J:167229
|
|
decreased ventricle muscle contractility |
J:167229
|
|
normal
growth/size/body region phenotype |
J:167229
|
|
normal
mortality/aging |
J:167229
|
|
normal
skeleton phenotype |
J:167229
|
Lmnatm9Lgf/Lmnatm9Lgf
involves: 129P2/OlaHsd * C57BL/6
|
normal
behavior/neurological phenotype |
J:207144
|
|
normal
mortality/aging |
J:207144
|
|
normal
nervous system phenotype |
J:207144
|
Lmnatm10Lgf/Lmnatm10Lgf
involves: 129P2/OlaHsd * C57BL/6
|
normal
behavior/neurological phenotype |
J:207144
|
|
normal
mortality/aging |
J:207144
|
|
normal
nervous system phenotype |
J:207144
|
Lmnatm11Lgf/Lmna+
involves: 129P2/OlaHsd * C57BL/6
|
abnormal cholinergic neuron morphology |
J:220988
|
|
abnormal colon morphology |
J:220988
|
|
abnormal enteric neuron morphology |
J:220988
|
|
abnormal esophageal smooth muscle morphology |
J:220988
|
|
abnormal esophageal squamous epithelium morphology |
J:220988
|
|
abnormal interstitial cell of Cajal morphology |
J:220988
|
|
dilated esophagus |
J:220988
|
|
distended cecum |
J:220988
|
|
esophageal achalasia |
J:220988
|
|
normal
nervous system phenotype |
J:220988
|
|
premature death |
J:220988
|
|
normal
skeleton phenotype |
J:220988
|
|
weight loss |
J:220988
|
Lmnatm11Lgf/Lmnatm11Lgf
involves: 129P2/OlaHsd * C57BL/6
|
decreased body size |
J:220988
|
|
normal
nervous system phenotype |
J:220988
|
|
premature death |
J:220988
|
Lmnatm12Lgf/Lmnatm12Lgf
involves: 129P2/OlaHsd * C57BL/6
|
abnormal aorta smooth muscle morphology |
J:234711
|
|
abnormal aorta tunica adventitia morphology |
J:234711
|
Excel File
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