Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UMOD
  • Mouse genes Umod
  • Rat genes Umod
  • Zfish genes si:ch211-226h7.3,si:dkey-239b22.2,zgc:153932
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Umod

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019864	IgG binding	UMOD	IDA		Human	PMID:20798515
Molecular Function	GO:0005515	protein binding	UMOD	IPI	UniProtKB:Q9BWP8:PRO_0000315044	Human	PMID:32045104
Molecular Function	GO:0005515	protein binding	UMOD	IPI	UniProtKB:P08191	Human	PMID:32616672
Molecular Function	GO:0005515	protein binding	Umod	IPI	UniProtKB:P20029	Mouse	PMID:28437467
Molecular Function	GO:0005515	protein binding	Umod	IPI	UniProtKB:P27773	Mouse	PMID:28437467
Molecular Function	GO:0005515	protein binding	Umod	IPI	UniProtKB:P35564	Mouse	PMID:28437467
Molecular Function	GO:0005515	protein binding	Umod	IPI	RGD:735082	Rat	PMID:18830570|RGD:2324702
Cellular Component	GO:0045177	apical part of cell	Umod	IDA		Rat	PMID:3910623|RGD:2324706
Cellular Component	GO:0016324	apical plasma membrane	UMOD	IDA		Human	PMID:18025791
Cellular Component	GO:0016324	apical plasma membrane	UMOD	IDA		Human	PMID:20798515
Cellular Component	GO:0016324	apical plasma membrane	UMOD	IDA		Human	PMID:7028707
Cellular Component	GO:0016324	apical plasma membrane	Umod	IDA		Mouse	PMID:30007527
Cellular Component	GO:0016324	apical plasma membrane	Umod	IDA		Mouse	PMID:21397062
Cellular Component	GO:0016323	basolateral plasma membrane	UMOD	IDA		Human	PMID:20798515
Cellular Component	GO:0016323	basolateral plasma membrane	UMOD	IDA		Human	PMID:7028707
Cellular Component	GO:0005929	cilium	UMOD	IDA		Human	PMID:20172860
Cellular Component	GO:0005929	cilium	Umod	IDA		Mouse	PMID:20172860
Cellular Component	GO:0031410	cytoplasmic vesicle	Umod	IDA		Rat	PMID:3910623|RGD:2324706
Cellular Component	GO:0005783	endoplasmic reticulum	Umod	IDA		Mouse	PMID:22237754
Cellular Component	GO:0070062	extracellular exosome	UMOD	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	UMOD	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	Umod	IDA		Mouse	PMID:22237754
Cellular Component	GO:0005615	extracellular space	Umod	IDA		Rat	PMID:16807540|RGD:2324704
Cellular Component	GO:0005794	Golgi apparatus	Umod	IDA		Rat	PMID:3910623|RGD:2324706
Cellular Component	GO:0016020	membrane	UMOD	IDA		Human	PMID:2249987
Cellular Component	GO:0045121	membrane raft	Umod	IDA		Rat	PMID:17082358|RGD:2324703
Cellular Component	GO:0005886	plasma membrane	Umod	IDA		Mouse	PMID:22237754
Cellular Component	GO:0000922	spindle pole	UMOD	IDA		Human	PMID:20172860
Biological Process	GO:0140367	antibacterial innate immune response	UMOD	IDA		Human	PMID:32616672
Biological Process	GO:0006915	apoptotic process	Umod	IMP		Mouse	PMID:29145399
Biological Process	GO:0097190	apoptotic signaling pathway	Umod	IMP		Mouse	PMID:28990932
Biological Process	GO:0006914	autophagy	Umod	IMP		Mouse	PMID:28990932
Biological Process	GO:0055074	calcium ion homeostasis	Umod	IMP		Mouse	PMID:20591941
Biological Process	GO:0055074	calcium ion homeostasis	Umod	IMP		Mouse	PMID:30007527
Biological Process	GO:0033554	cellular response to stress	Umod	IMP		Mouse	PMID:28785050
Biological Process	GO:0034620	cellular response to unfolded protein	Umod	IMP		Mouse	PMID:28437467
Biological Process	GO:0061077	chaperone-mediated protein folding	Umod	IMP		Mouse	PMID:28437467
Biological Process	GO:0048878	chemical homeostasis	Umod	IMP	MGI:MGI:3712284	Mouse	PMID:17264314
Biological Process	GO:0032602	chemokine production	Umod	IMP		Mouse	PMID:28785050
Biological Process	GO:0055064	chloride ion homeostasis	Umod	IMP		Mouse	PMID:29357410
Biological Process	GO:0046720	citric acid secretion	Umod	IMP		Mouse	PMID:20591941
Biological Process	GO:0072044	collecting duct development	Umod	IMP		Mouse	PMID:17898038
Biological Process	GO:0097709	connective tissue replacement	Umod	IMP		Mouse	PMID:28785050
Biological Process	GO:0097709	connective tissue replacement	Umod	IMP		Mouse	PMID:29145399
Biological Process	GO:0050829	defense response to Gram-negative bacterium	UMOD	IDA		Human	PMID:32616672
Biological Process	GO:0050829	defense response to Gram-negative bacterium	Umod	IMP		Mouse	PMID:14871399
Biological Process	GO:0050829	defense response to Gram-negative bacterium	Umod	IMP		Mouse	PMID:14665435
Biological Process	GO:0007029	endoplasmic reticulum organization	Umod	IMP		Mouse	PMID:28437467
Biological Process	GO:0010467	gene expression	Umod	IMP		Mouse	PMID:15522986
Biological Process	GO:0010467	gene expression	Umod	IMP		Mouse	PMID:22237754
Biological Process	GO:0010467	gene expression	Umod	IMP		Mouse	PMID:28437467
Biological Process	GO:0010467	gene expression	Umod	IMP		Mouse	PMID:28785050
Biological Process	GO:0010467	gene expression	Umod	IMP		Mouse	PMID:29145399
Biological Process	GO:0010467	gene expression	Umod	IMP		Mouse	PMID:29357410
Biological Process	GO:0010467	gene expression	Umod	IMP		Mouse	PMID:30007527
Biological Process	GO:0003094	glomerular filtration	Umod	IMP		Mouse	PMID:15522986
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	UMOD	IDA		Human	PMID:20798515
Biological Process	GO:0006954	inflammatory response	Umod	IMP		Mouse	PMID:28785050
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Umod	IMP		Mouse	PMID:17898038
Biological Process	GO:0030644	intracellular chloride ion homeostasis	Umod	IMP		Mouse	PMID:17898038
Biological Process	GO:0030644	intracellular chloride ion homeostasis	Umod	IDA		Mouse	PMID:21737451
Biological Process	GO:0030643	intracellular phosphate ion homeostasis	Umod	IMP		Mouse	PMID:17898038
Biological Process	GO:0006883	intracellular sodium ion homeostasis	Umod	IMP		Mouse	PMID:17898038
Biological Process	GO:0072051	juxtaglomerular apparatus development	Umod	IMP		Mouse	PMID:15522986
Biological Process	GO:0001822	kidney development	Umod	IMP		Mouse	PMID:28990932
Biological Process	GO:0001822	kidney development	Umod	IMP		Mouse	PMID:29145399
Biological Process	GO:0007159	leukocyte cell-cell adhesion	UMOD	IDA		Human	PMID:20798515
Biological Process	GO:0006629	lipid metabolic process	Umod	IMP		Mouse	PMID:28785050
Biological Process	GO:0072070	loop of Henle development	Umod	IMP		Mouse	PMID:15522986
Biological Process	GO:0072218	metanephric ascending thin limb development	Umod	IEP		Mouse	MGI:MGI:3806730|PMID:18618131
Biological Process	GO:0072221	metanephric distal convoluted tubule development	Umod	IEP		Mouse	MGI:MGI:3806730|PMID:18618131
Biological Process	GO:0072233	metanephric thick ascending limb development	Umod	IEP		Mouse	MGI:MGI:3806730|PMID:18618131
Biological Process	GO:0060073	micturition	Umod	IMP		Mouse	PMID:19214995
Biological Process	GO:0050801	monoatomic ion homeostasis	Umod	IMP		Mouse	MGI:MGI:5009417|PMID:15327412
Biological Process	GO:0033555	multicellular organismal response to stress	Umod	IMP		Mouse	PMID:19214995
Biological Process	GO:0048871	multicellular organismal-level homeostasis	Umod	IMP		Mouse	PMID:29145399
Biological Process	GO:0050891	multicellular organismal-level water homeostasis	Umod	IMP		Mouse	PMID:29357410
Biological Process	GO:1990266	neutrophil migration	UMOD	IDA		Human	PMID:20798515
Biological Process	GO:0002251	organ or tissue specific immune response	Umod	IMP		Mouse	PMID:28990932
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	Umod	IMP		Mouse	PMID:30007527
Biological Process	GO:0055062	phosphate ion homeostasis	Umod	IMP		Mouse	PMID:20591941
Biological Process	GO:0055075	potassium ion homeostasis	Umod	IMP		Mouse	PMID:29357410
Biological Process	GO:0072665	protein localization to vacuole	Umod	IMP		Mouse	PMID:21081491
Biological Process	GO:0006468	protein phosphorylation	Umod	IMP		Mouse	PMID:21737451
Biological Process	GO:0006468	protein phosphorylation	Umod	IDA		Mouse	PMID:21737451
Biological Process	GO:0044861	protein transport into plasma membrane raft	Umod	IMP		Mouse	PMID:29357410
Biological Process	GO:0008217	regulation of blood pressure	Umod	IMP		Mouse	PMID:29357410
Biological Process	GO:0051223	regulation of protein transport	Umod	IMP		Mouse	PMID:29145399
Biological Process	GO:0051223	regulation of protein transport	Umod	IMP		Mouse	PMID:29357410
Biological Process	GO:0035809	regulation of urine volume	Umod	IMP		Mouse	PMID:29145399
Biological Process	GO:0035809	regulation of urine volume	Umod	IMP		Mouse	PMID:29357410
Biological Process	GO:0070294	renal sodium ion absorption	Umod	IMP		Mouse	PMID:21737451
Biological Process	GO:0070294	renal sodium ion absorption	Umod	IDA		Mouse	PMID:21737451
Biological Process	GO:0097744	renal urate salt excretion	Umod	IMP		Mouse	PMID:29357410
Biological Process	GO:0003091	renal water homeostasis	Umod	IMP		Mouse	PMID:15522986
Biological Process	GO:0036270	response to diuretic	Umod	IMP		Mouse	PMID:29357410
Biological Process	GO:0034976	response to endoplasmic reticulum stress	Umod	IMP		Mouse	PMID:28990932
Biological Process	GO:0032496	response to lipopolysaccharide	Umod	IDA		Mouse	PMID:3356692
Biological Process	GO:0010033	response to organic substance	Umod	IEP		Rat	PMID:16807540|RGD:2324704
Biological Process	GO:0006986	response to unfolded protein	Umod	IMP		Mouse	PMID:29145399
Biological Process	GO:0009414	response to water deprivation	Umod	IMP		Mouse	PMID:15522986
Biological Process	GO:0009410	response to xenobiotic stimulus	Umod	IMP		Mouse	PMID:30007527
Biological Process	GO:0008380	RNA splicing	Umod	IMP		Mouse	PMID:28437467
Biological Process	GO:0055078	sodium ion homeostasis	Umod	IMP		Mouse	PMID:29357410
Biological Process	GO:0055078	sodium ion homeostasis	Umod	IMP		Mouse	PMID:30007527
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	Umod	IMP		Mouse	PMID:28990932
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	Umod	IMP		Mouse	PMID:28437467
Biological Process	GO:0015747	urate transport	Umod	IMP		Mouse	PMID:29357410
Biological Process	GO:0071918	urea transmembrane transport	Umod	IMP	MGI:MGI:3712284	Mouse	PMID:17264314

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern