About   Help   FAQ
Gene Ontology Browser
Term Detail
GO term:cellular response to unfolded protein
Synonym: heat shock protein activity
GO id:GO:0034620
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
CommentsNote that this term should not be confused with 'unfolded protein response ; GO:0030968', which refers to the signaling pathways that respond to the presence of unfolded proteins in the ER.
Number of paths to term: 11

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-acellular response to chemical stimulus
                                        is-acellular response to organic substance
                                                is-acellular response to topologically incorrect protein
                                                        is-acellular response to misfolded protein +
                                                        is-acellular response to unfolded protein [GO:0034620] (58 genes, 85 annotations)
                                                                part-ofendoplasmic reticulum unfolded protein response +
                                                                is-amitochondrial unfolded protein response +


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-acellular response to stress
                                        is-acellular response to topologically incorrect protein
                                                is-acellular response to misfolded protein +
                                                is-acellular response to unfolded protein [GO:0034620] (58 genes, 85 annotations)
                                                        part-ofendoplasmic reticulum unfolded protein response +
                                                        is-amitochondrial unfolded protein response +


obsolete Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-acellular response to chemical stimulus
                                        is-acellular response to organic substance
                                                is-acellular response to topologically incorrect protein
                                                        is-acellular response to misfolded protein +
                                                        is-acellular response to unfolded protein [GO:0034620] (58 genes, 85 annotations)
                                                                part-ofendoplasmic reticulum unfolded protein response +
                                                                is-amitochondrial unfolded protein response +


obsolete Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-acellular response to stress
                                        is-acellular response to topologically incorrect protein
                                                is-acellular response to misfolded protein +
                                                is-acellular response to unfolded protein [GO:0034620] (58 genes, 85 annotations)
                                                        part-ofendoplasmic reticulum unfolded protein response +
                                                        is-amitochondrial unfolded protein response +


obsolete Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-acellular response to chemical stimulus
                                        is-acellular response to organic substance
                                                is-acellular response to topologically incorrect protein
                                                        is-acellular response to misfolded protein +
                                                        is-acellular response to unfolded protein [GO:0034620] (58 genes, 85 annotations)
                                                                part-ofendoplasmic reticulum unfolded protein response +
                                                                is-amitochondrial unfolded protein response +


obsolete Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to organic substance
                                        is-acellular response to organic substance
                                                is-acellular response to topologically incorrect protein
                                                        is-acellular response to misfolded protein +
                                                        is-acellular response to unfolded protein [GO:0034620] (58 genes, 85 annotations)
                                                                part-ofendoplasmic reticulum unfolded protein response +
                                                                is-amitochondrial unfolded protein response +


obsolete Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to organic substance
                                        is-aresponse to topologically incorrect protein
                                                is-acellular response to topologically incorrect protein
                                                        is-acellular response to misfolded protein +
                                                        is-acellular response to unfolded protein [GO:0034620] (58 genes, 85 annotations)
                                                                part-ofendoplasmic reticulum unfolded protein response +
                                                                is-amitochondrial unfolded protein response +


obsolete Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to organic substance
                                        is-aresponse to topologically incorrect protein
                                                is-aresponse to unfolded protein
                                                        is-acellular response to unfolded protein [GO:0034620] (58 genes, 85 annotations)
                                                                part-ofendoplasmic reticulum unfolded protein response +
                                                                is-amitochondrial unfolded protein response +
                                                        is-adetection of unfolded protein


obsolete Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to stress
                                is-acellular response to stress
                                        is-acellular response to topologically incorrect protein
                                                is-acellular response to misfolded protein +
                                                is-acellular response to unfolded protein [GO:0034620] (58 genes, 85 annotations)
                                                        part-ofendoplasmic reticulum unfolded protein response +
                                                        is-amitochondrial unfolded protein response +


obsolete Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to stress
                                is-aresponse to topologically incorrect protein
                                        is-acellular response to topologically incorrect protein
                                                is-acellular response to misfolded protein +
                                                is-acellular response to unfolded protein [GO:0034620] (58 genes, 85 annotations)
                                                        part-ofendoplasmic reticulum unfolded protein response +
                                                        is-amitochondrial unfolded protein response +


obsolete Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to stress
                                is-aresponse to topologically incorrect protein
                                        is-aresponse to unfolded protein
                                                is-acellular response to unfolded protein [GO:0034620] (58 genes, 85 annotations)
                                                        part-ofendoplasmic reticulum unfolded protein response +
                                                        is-amitochondrial unfolded protein response +
                                                is-adetection of unfolded protein


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/18/2015
MGI 6.0
The Jackson Laboratory