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Gene Ontology Browser
Term Detail
GO term:extracellular space
Synonym: intercellular space
GO id:GO:0005615
Definition:That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
CommentsNote that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-acellular_component
                is-aextracellular region
                        part-ofextracellular region part
                                is-aactivin complex +
                                is-aanchoring collagen complex +
                                is-aangiogenin-PRI complex
                                is-aapical lamina of hyaline layer
                                is-aapoptotic body
                                is-abasal lamina +
                                is-abasement membrane +
                                is-abasement membrane collagen trimer +
                                is-ablood microparticle +
                                is-abursicon neuropeptide hormone complex
                                is-aclassical-complement-pathway C3/C5 convertase complex
                                is-aCNTFR-CLCF1 complex
                                is-acollagen and cuticulin-based cuticle extracellular matrix part +
                                is-acollagen type IV trimer
                                is-acollagen type XIX trimer
                                is-acollagen type XV trimer
                                is-acollagen type XXVI trimer
                                is-acollagen type XXVII trimer
                                is-acollagen type XXVIII trimer
                                is-acomplement component C1 complex
                                is-aCRLF-CLCF1 complex
                                is-aextra-invasive hyphal space
                                is-aextracellular ferritin complex
                                is-aextracellular isoamylase complex
                                is-aextracellular organelle +
                                is-aextracellular space [GO:0005615] (1171 genes, 1488 annotations)
                                        part-ofactivin complex +
                                        part-ofblood microparticle +
                                        part-ofbursicon neuropeptide hormone complex
                                        part-ofclassical-complement-pathway C3/C5 convertase complex
                                        part-ofCNTFR-CLCF1 complex
                                        part-ofcomplement component C1 complex
                                        part-ofCRLF-CLCF1 complex
                                        part-offibrinogen complex
                                        part-ofimmunoglobulin complex, circulating +
                                        part-ofinhibin complex +
                                        part-ofinsulin-like growth factor binding protein complex +
                                        part-ofinterleukin-12 complex
                                        part-ofinterleukin-23 complex
                                        part-ofinterleukin-27 complex
                                        part-ofinterleukin-35 complex
                                        part-oflarval serum protein complex
                                        part-ofplasma lipoprotein particle +
                                is-aextracellular space of host +
                                is-aextrahaustorial matrix
                                is-aextraorganismal space +
                                is-afemale germline ring canal inner rim
                                is-afemale germline ring canal outer rim
                                is-afibril +
                                is-afibrillar collagen trimer +
                                is-afibrinogen complex
                                is-afollicle-stimulating hormone complex
                                is-ahyaluranon cable
                                is-aimmunoglobulin complex, circulating +
                                is-ainhibin complex +
                                is-ainsulin-like growth factor binding protein complex +
                                is-aintercellular bridge +
                                is-ainterleukin-12 complex
                                is-ainterleukin-23 complex
                                is-ainterleukin-27 complex
                                is-ainterleukin-35 complex
                                is-alamina densa
                                is-alamina lucida
                                is-alamina reticularis
                                is-alaminin complex +
                                is-alarval serum protein complex
                                is-amucus layer +
                                is-aother organism part +
                                is-aplasma lipoprotein particle +
                                is-aproteinaceous extracellular matrix +
                                is-ascaffoldin complex
                                is-asheet-forming collagen trimer +
                                is-asublamina densa
                                is-aVEGF-A complex


Gene_Ontology
        is-acellular_component
                is-aextracellular region part
                        is-aactivin complex +
                        is-aanchoring collagen complex +
                        is-aangiogenin-PRI complex
                        is-aapical lamina of hyaline layer
                        is-aapoptotic body
                        is-abasal lamina +
                        is-abasement membrane +
                        is-abasement membrane collagen trimer +
                        is-ablood microparticle +
                        is-abursicon neuropeptide hormone complex
                        is-aclassical-complement-pathway C3/C5 convertase complex
                        is-aCNTFR-CLCF1 complex
                        is-acollagen and cuticulin-based cuticle extracellular matrix part +
                        is-acollagen type IV trimer
                        is-acollagen type XIX trimer
                        is-acollagen type XV trimer
                        is-acollagen type XXVI trimer
                        is-acollagen type XXVII trimer
                        is-acollagen type XXVIII trimer
                        is-acomplement component C1 complex
                        is-aCRLF-CLCF1 complex
                        is-aextra-invasive hyphal space
                        is-aextracellular ferritin complex
                        is-aextracellular isoamylase complex
                        is-aextracellular organelle +
                        is-aextracellular space [GO:0005615] (1171 genes, 1488 annotations)
                                part-ofactivin complex +
                                part-ofblood microparticle +
                                part-ofbursicon neuropeptide hormone complex
                                part-ofclassical-complement-pathway C3/C5 convertase complex
                                part-ofCNTFR-CLCF1 complex
                                part-ofcomplement component C1 complex
                                part-ofCRLF-CLCF1 complex
                                part-offibrinogen complex
                                part-ofimmunoglobulin complex, circulating +
                                part-ofinhibin complex +
                                part-ofinsulin-like growth factor binding protein complex +
                                part-ofinterleukin-12 complex
                                part-ofinterleukin-23 complex
                                part-ofinterleukin-27 complex
                                part-ofinterleukin-35 complex
                                part-oflarval serum protein complex
                                part-ofplasma lipoprotein particle +
                        is-aextracellular space of host +
                        is-aextrahaustorial matrix
                        is-aextraorganismal space +
                        is-afemale germline ring canal inner rim
                        is-afemale germline ring canal outer rim
                        is-afibril +
                        is-afibrillar collagen trimer +
                        is-afibrinogen complex
                        is-afollicle-stimulating hormone complex
                        is-ahyaluranon cable
                        is-aimmunoglobulin complex, circulating +
                        is-ainhibin complex +
                        is-ainsulin-like growth factor binding protein complex +
                        is-aintercellular bridge +
                        is-ainterleukin-12 complex
                        is-ainterleukin-23 complex
                        is-ainterleukin-27 complex
                        is-ainterleukin-35 complex
                        is-alamina densa
                        is-alamina lucida
                        is-alamina reticularis
                        is-alaminin complex +
                        is-alarval serum protein complex
                        is-amucus layer +
                        is-aother organism part +
                        is-aplasma lipoprotein particle +
                        is-aproteinaceous extracellular matrix +
                        is-ascaffoldin complex
                        is-asheet-forming collagen trimer +
                        is-asublamina densa
                        is-aVEGF-A complex


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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory