About   Help   FAQ
Gene Ontology Browser
Term Detail
GO term:inflammatory response
Synonym: Inflammation
GO id:GO:0006954
Definition:The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
CommentsThis term was improved by GO_REF:0000022. It was moved.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to stress
                                is-adefense response
                                        is-abehavioral defense response +
                                        is-acellular defense response +
                                        is-aclearance of foreign intracellular DNA +
                                        is-adefense response by callose deposition +
                                        part-ofdefense response by callose deposition in cell wall
                                        is-adefense response by cell wall thickening +
                                        is-adefense response to other organism +
                                        is-adefense response to tumor cell
                                        is-ainflammatory response [GO:0006954] (471 genes, 659 annotations)
                                                is-aacute inflammatory response +
                                                is-achronic inflammatory response +
                                                is-ainflammatory response to antigenic stimulus +
                                                part-ofleukocyte activation involved in inflammatory response
                                                part-ofleukocyte migration involved in inflammatory response +
                                                negatively-regulatesnegative regulation of inflammatory response +
                                                positively-regulatespositive regulation of inflammatory response +
                                                part-ofproduction of molecular mediator involved in inflammatory response +
                                                regulatesregulation of inflammatory response +
                                                part-ofwound healing involved in inflammatory response +
                                        is-ainnate immune response +
                                        negatively-regulatesnegative regulation of defense response +
                                        positively-regulatespositive regulation of defense response +
                                        regulatesregulation of defense response +
                                        part-ofrespiratory burst involved in defense response +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to stress
                                is-aresponse to wounding
                                        is-abehavioral response to wounding
                                        is-adetection of wounding +
                                        is-ainflammatory response [GO:0006954] (471 genes, 659 annotations)
                                                is-aacute inflammatory response +
                                                is-achronic inflammatory response +
                                                is-ainflammatory response to antigenic stimulus +
                                                part-ofleukocyte activation involved in inflammatory response
                                                part-ofleukocyte migration involved in inflammatory response +
                                                negatively-regulatesnegative regulation of inflammatory response +
                                                positively-regulatespositive regulation of inflammatory response +
                                                part-ofproduction of molecular mediator involved in inflammatory response +
                                                regulatesregulation of inflammatory response +
                                                part-ofwound healing involved in inflammatory response +
                                        is-ajasmonic acid and ethylene-dependent systemic resistance +
                                        negatively-regulatesnegative regulation of response to wounding +
                                        positively-regulatespositive regulation of response to wounding +
                                        regulatesregulation of response to wounding +
                                        is-aresponse to axon injury +
                                        is-aresponse to injury involved in regulation of muscle adaptation +
                                        is-awound healing +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/12/2014
MGI 5.19
The Jackson Laboratory